이하선에 발생한 다형선종유래암종의 치험례

정진환,이상칠,김동우,박대송,이슬기,박철휘,염학렬,김현민,송민석,Jung, Jin-Hwan,Lee, Sang-Chil,Kim, Dong-Woo,Park, Dae-Song,Lee, Seul-Ki,Park, Chul-Hui,Yeom, Hak-Ryul,Kim, Hyeon-Min,Song, Min-Seok 대한구강악안면외과학회 2010 대한구강악안면외과학회지 Vol.36 No.1

Carcinoma ex pleomorphic adenoma is transformed at the incidence of 1-20% in pleomorphic adenoma and frequently recurred. It accounts for 10% of all malignant salivary tumors and its average age of occurrence is 60s. It will present in a large, long-standing pleomorphic adenoma or in one that was previously treated but has recurred. According to cell composition in malignant cell carcinoma, and clear cell adenocarcinoma. Most (75%) occur in parotid gland, while about 20% occur in the minor gland of the oral mucosa. The metastasis rate to regional lymph node is about 25%, and to distant organs about 33% and the 5-year survival rates are 40%. Though the treatment of the carcinoma ex pleomorphic adenoma is not established, it is treated ideally with and extensive resection, neck dissection, postoperative radiotherapy, and chemotherapy. When occurred in parotid gland, facial paralysis is reported. With a review of literatures, we report a case of carcinoma ex pleomorphic adenoma which operated with total parotidectomy and supraomohyoid neck dissection.

하악과두하 골절 시 후하악 접근법과 내시경을 이용한 구강 내 접근의 비교

김동우,박대송,이상칠,김성용,임호용,염학열,김현민,Kim, Dong-Woo,Park, Dae-Song,Lee, Sang-Chil,Kim, Sung-Yong,Lim, Ho-Yong,Yeom, Hak-Yeol,Kim, Hyeon-Min 대한악안면성형재건외과학회 2011 Maxillofacial Plastic Reconstructive Surgery Vol.33 No.6

Purpose: Patients who had a subcondylar fracture with a displaced or deviated condylar segment were treated with a retromandibular approach (RMA) or an endoscope-assisted transoral approach (EATA) in our department of oral and maxillofacial surgery. The clinical results of the approaches were compared. A comparative study of specific approaches for subcondylar fractures has not been published before in Korea. Methods: Twenty-one patients with subcondylar fractures of the mandible were included. Ten patients were treated with the retromandibular approach and 11 were treated with an endoscope-assisted transoral approach. We examined patient age, gender, fracture sites, classifications, period of maxillomandibular fixation, facial nerve (FN) or greater auricular nerve (GAN) injuries, maximal mouth opening, deflection, occlusal changes, number of plates, follow-up period, and other complications. Preoperative computed tomography and pre-operative, post-operative, and follow-up panoramic views were taken of each patient. Results: Mean maximal mouth openings were similar between the two approaches. FN and GAN injuries were more frequent in the RMA group but the deflective rate with mouth opening was higher in the EATA than that in RMA group. Two cases of post-operative infection occurred in the EATA group, and occlusal changes were observed in one case for both approaches. Conclusion: The RMA offers more direct access and visualization of the surgical field but it can cause scars and retractive injuries of the FN and GAN. But, EATA did not result in consequent nerve injuries or scars postoperatively, but unfavorable fractures such as $medial$ $override$ condyles were more difficult to reduce endoscopically. Except cases of an expected difficult reduction, the treatment of choice for a displaced subcondylar fracture may be an EATA.

치근단 감염 치아의 치근단 수술 후 예후에 관한 후향적 연구

김현민,박철휘,이상칠,김동우,박대송,정진환,이슬기,송민석,Kim, Hyeon-Min,Park, Chul-Hwi,Lee, Sang-Chil,Kim, Dong-Woo,Park, Dae-Song,Jung, Jin-Hwan,Lee, Seul-Ki,Song, Min-Seok 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.3

Purpose: The purpose of this retrospective clinical study was to monitor the outcomes of periapical surgery in periapically infected tooth with or without retrograde filling materials (MTA or IRM). Patients and Methods: A total of 85 teeth in 63 patients were included in the study between November 2004 and August 2008. Randomly, MTA or IRM was used as a retrograde filling material or only apical resection without retrograde filling. Teeth with advanced periodontal bone loss or presence of root fracture were excluded from the study. The patients were subjected to a minimum follow-up period of 12 months, with a mean of 17.1 months. Results: Successful healing was observed in 83.3% of the MTA-treated teeth, 80% of the IRM-treated teeth and 75% of the teeth which was not retrograde filling. Doubtful healing was seen 9.3% (MTA), 13.3% (IRM), 12.5% (no retro-filling). The success rate of upper incisors (92%) was higher than lower lincisor and molars (66.7% and 50%, respectively). Conclusion: In this study, periapical surgery including retrograde filling improves the prognosis. And, no statistically significant differences were found between retrograde filling materials (MTA or IRM).

낭종성 법랑모세포종으로 인하여 매복된 하악 구치의 교정-외과 치료: 증례보고

문철현,김현민,박대송,김동우,이상칠,김성용,임호용,염학열,Moon, Cheol-Hyun,Kim, Hyeon-Min,Park, Dae-Song,Kim, Dong-Woo,Lee, Sang-Chil,Kim, Sung-Yong,Lim, Ho-Yong,Yeom, Hak-Yeol 대한악안면성형재건외과학회 2011 Maxillofacial Plastic Reconstructive Surgery Vol.33 No.5

Ameloblastoma is an aggressive benign odontogenic epithelial tumour that may arise from the enamel organ, remnants of dental lamina, or the lining of an odontogenic cyst. It is usually categorized into solid or multicystic, unicystic, and peripheral types. Treatment ofameloblastomas include conservative methods such as marsupialisation, enucleation, and curettage; and radical treatments such as marginal or segmental resection. Radical treatments have resulted in lower recurrence rates; however, may also encounter esthetic, functional, and reconstructive problems. Unicystic ameloblastoma has been considered less aggressive and a lower recurrence tendency. Thus, many authors have recommended conservative treatment in cases of unicystic ameloblastoma. An 11 year-old boy presented with displaced second and third molars by luminal unicystic ameloblastoma in the mandible. Cyst enucleation, curettage, and third molar extraction were done. No signs of recurrence or esthetic problems such as facial asymmetry were seen radiologically and clinically, up to 8 years 2 months postoperatively.

대가중의 중금속 분석을 위한 여지의 전처리 방법에 관한 연구

김광래(Kwang-Rae Kim),이상칠(Sang-Chil Lee),어수미(Soo-Mi Eo),김민영(Min-Young Kim),신재영(Jae-Young Shin),이재영(Jai-Young Lee) 한국환경보건학회 2002 한국환경보건학회 학술대회 자료집 Vol.2002 No.-

혈액 투석 환자에서 혈전 생성에 의한 동정맥루 폐쇄와 Anticardiolipin Antibody 및 Lipoprotein ( a ) 와의 연관성에 관한 연구

장미경(Mi Kyung Chang),이상칠(Sang Chil Lee),차대룡(Dae Ryong Cha),권영주(Young Joo Kwon),조원용(Won Yong Cho),표희정(Hee Jeong Pyo),김형규(Hyoung Kyu Kim) 대한내과학회 1997 대한내과학회지 Vol.52 No.4

N/A Objectives: Arteriovenous fistula (AVF) is Achilles hill of patients receiving maintenance hemodialysis, but thrombosis of AVF is a frequently encountered problem in maintenance hemodialysis patients. AVF thrombosis or occlusion is known to be associated with old age, underlying diabetes mellitus, increased fibrinogen and factor VIII, short AVF maturation time, low dialyzer blood flow, etc. Recently, several reports suggested that high titer of IgG anticardiolipin antibody (IgG-ACA) is associated with single or repeated clotting of AVF and elevated Lp(a) level is associated with vascular access occlusion in patients under maintenance hemodialysis. This study is to investigate the relationship between AVF thrombosis and the presence of elevated titiers of LP (a) and IgG-ACA. Methods: This study included 20 patients with end stage renal disease under hemodialysis via AVF. Ten subjects have had one or more episodes of AVF obstruction (group A). Another 10 subjects without episodes of AVF obstruction (group B) were selected matching with age, sex, underlying disease, duration of hemodialysis, blood glucose level and lipid profile of subjects in group A. The IgG, IgM anticardiolipin antibody titers with indirect ELISA method and LP (a) level with turbidimetric assay were measured and analysed. Results: Four subjects in group A showed positive IgG-ACA titer what of all subjects in group B were negative titer (p=0.03). Only one subject in group A and two subjects in group B showed positive IgM-ACA titer (p>0.05). The median value of Lp (a) was 32.75 (mg/dl), 43.1 (mg/dl) in group A and group B respectively and was not significantly different each other (p>0.05). Conclusions: In end stage renal patients receiving hemodialysis, positive IgG-ACA titier seems to be an independent risk factor of AVF thrombosis.

한국인의 혈중 Lipoprotein ( a ) 농도와 Apolipoprotein ( a ) 유전적 표현형 분포특성

서홍석(Hong Seog Seo),오동주(Dong Joo Oh),이상칠(Sang Chil Lee),임도선(Do Sun Lim),박창규(Chang Kyu Park),김영훈(Young Hoon Kim),심완주(Wan Joo Shim),노영무(Young Moo Ro),김순덕(Soon Duk Kim),유재명(Jae Myung Yu) 대한내과학회 1996 대한내과학회지 Vol.50 No.5

N/A Lipoprotein(a)[Lp(a)] is a cholestryl ester-rich lipoprotein composed of two components' an LDL -like particle to which is attached a single large glycoprotein, apolipoprotein(a)[apo(a)]. Elevated concentrations of Lp(a) have been established as a geneticalqly controlled risk factor for atherosclerotic vascular disease. Variable alleles at the apo(a) gene locus determine, to a large extent, the Lp(a) concentration in the general population. To determine and compare the mean and distribution of Lp(a) concentration, apo(a) phenotypes and allele frequencies of Lp(a) in Korean people and other several esthnic groups, we investigated the Lp(a) plasma concentration, apo(a) phenotypes and other lipid profiles in 481 Korean People, who were consisted of 280 cases with non-atherosclerotic vascular disease and 201rases with atherosclerotic vascular disease. Mean concentrations of Lp(a) in Korean people were 27.3±28.6mg/dl in cases with non-atherosclerotic vascular disease an 29.9±31.2mg/dl in cases with atherocslerotic vascular disease. No differences was found in Lp(a) doncentration between the two groups. Lp(a) concentration of Korean people was simular to those of Indian, but far higher than those of Caucacian, Chinese or Japanese. Proportion of those below 5mg/dl of Lp(a) concentration was 26.6%, and those below 30mg/ dl was 68.0%. Frequency distribution patterns of Lp(a) concentrations in Korean population were similar to those of Chinese, Japanese and Malysian, but different from those of Caucacian, Indian of African. In apo(a) phenotype of Korean, the mode of single band was S3(44.3%), and the mode of double bank was S3S4(8.2%), which were similar to those of Chinese, Malysian and Indian. Order of allele frequencies of Lp(a) of Korean was Lps4, null(Lp0), Lps3, Lps2, and Lps1. Similar frequency was seen in those of Chinese, and other Asians execpt Japanese, but not in those of Caucacian and black people. Lp(a) concentration was not correlated with any other lipid profiles. Homology of study samples with Korean population was confirmed by Hardy-Weinberg equilibrium test. These results show that Korean people has higher concentration of Lp(a) in Asian, and has characteristics of apo(a) phenotype and Lp(a) allele frequences.

자기주도적 야외탐구활동에 대한 중학생의 인식 및 과학적 태도 분석

김창건 ( Chang Geon Kim ),고용철 ( Young Chul Ko ),이상칠 ( Sang Chil Lee ),강동식 ( Dong Shik Kang ) 부산대학교 과학교육연구소 2013 교사교육연구 Vol.52 No.3

이 연구의 목적은 자기주도적인 야외탐구활동에 대한 중학생들의 인식과 과학적 태도를 분석하기 위한 것이다. 연구대상은 2012년 7월 3박 4일간 제주대학교 과학영재교육원 주관으로 운영한 자기주도적 야외탐구활동에 참여한 50명의 중학생이다. 이 연구에서는 학생들의 야외탐구활동에 대한 인식과 과학적 태도를 조사했고, 기존 야외탐구활동 경험이 있는 집단과 야외탐구활동 경험이 없는 집단 간에 차이가 있는지를 t-검증을 통해 분석하였다. 자기주도적 야외탐구활동에 대한 흥미도를 조사한 결과 야외탐구활동 경험이 있는 학생 집단의 평균 점수가 경험이 없는 학생 집단에 비해 높게 나타났으며, t-검증 결과 통계적으로 유의미한 차이를 보였다. 또한 자기주도적 야외탐구활동과 교실수업과의 관계에 대해 야외탐구 활동 경험이 있는 학생들이 야외탐구 활동의 가치를 더 높게 인식하고 있는 것으로 나타났다. 자기주도적 야외탐구활동을 통한 과학적 태도에서는 야외탐구활동 경험이 있는 집단과 경험이 없는 집단 간의 유의미한 차이가 나타나지 않는다. 그러나 과학적 태도 영역별 검사에서는 자기주도적 야외탐구활동은 과학적 태도 하위요소 중 적극성, 솔직성, 준비성 영역에서 차이가 있었다. 따라서 지속적으로 자기주도적 야외탐구활동 프로그램을 운영한다면 학생들의 과학적 태도 향상에 긍정적인 영향을 줄 수 있을 것으로 본다. The purpose of this study was to analyze the perception and scientific attitudes of middle school students toward self-directed field inquiry activities. The subjects of this study consisted of 50 students who participated in self-directed field inquiry activities for three nights and four days in July, 2012, which were run by Jeju National University-Affiliated Gifted Education Center. In this study, the perception and attitudes of the students in relation to inquiry-based field activities were examined and the differences between a group with a prior experience of field inquiry activitiesi and a group with no experience of field inquiry activities were analyzed using t-tests. According to the investigation on the students` interest in self-directed field inquiry activities, the group with an experience of ifield inquiry activities exhibited a higher average score than the group with no such experience. A t-test confirmed that the above difference between the groups was statistically significant. Moreover, in terms of the relations between self-directed field inquiry activities and classroom teaching, the students with an experience of field inquiry activities were revealed to recognize the value of field inquiry activities more highly than the students with no such experience. In terms of scientific attitudes according to self-directed field inquiry activities, no statistically significant differences were observed between the group with an experience of field inquiry activities and the group with no experience. However, through a scientific attitude test by sub-categories, the group with an experience of field inquiry activities revealed differences in terms of activeness, truthfulness, and preparedness. Therefore, the consistent operation of self-directed field inquiry activities is expected to have a positive effect on the improvement in the scientific attitudes of students.

멘토링을 활용한 과학탐구프로그램에 대한 중,고등학생들의 인식 -제1회 제주과학탐구아카데미 참여 학생을 중심으로-

고용철 ( Yong Chul Ko ),김창건 ( Chang Geon Kim ),이상칠 ( Sang Chil Lee ),강동식 ( Dong Shik Kang ) 경북대학교 과학교육연구소 2014 科學敎育硏究誌 Vol.38 No.1

이 연구는 멘토링을 활용한 과학탐구프로그램인 제주과학탐구아카데미에 참가한 학생들을 대상으로 멘토링 및 제주과학탐구아카데미에 대한 인식을 조사하기 위한 것이다. 연구 대상은 탐구계획서를 제 출하여 심사를 통해 선발되어 본 프로그램에 참가한 중학생 50명과 고등학생 50명이다. 멘토링에 대한 조사 결과 학생들은 멘토와의 상호작용을 통해 탐구에 대한 자신감을 가지게 되었고, 탐구에 대한 새로운 관점을 구축하게 되었다고 응답했다. 또한 과학탐구프로그램에 대한 인식을 조사한 결과 학생들은 이 탐구프로그램 활동에 많은 흥미를 느꼈고 과학 개념을 이해하는 데에도 도움이 된다고 응답 했다. 이 연구의 결과는 과학탐구 프로그램 개발에 있어서 멘토링 도입을 적극적으로 검토할 필요가있음을 나타내고 있다. 후속 연구로 과학탐구 프로그램 참여 경험이 학생들의 과학탐구력, 개념 이해등에 어떻게 영향을 미치는지 다양한 영향 요인에 대한 분석이 이루어져야 할 것이다. This study aims to investigate the opinions of students who joined the Jeju Scientific Research Academy, a scientific research program with a mentoring system. The 50 middle school students and 50high school students in the study were chosen as participants after being judged on their research plans. According to the study, students became more confident in research activities and could have a new point of view on research through interaction with a mentor. They were also very interested in the scientific research program of the Jeju Scientific Research Academy and found it helpful to understand the scientific concepts. Therefore the study shows it is necessary to consider actively the introduction of the mentoring system for the scientific research program. The follow-up study should be done to determine which factors influence on the inquiring minds and the understanding of scientific concepts of the students during the experience of the program.

활동 중심 STEAM 프로그램이 중학생들의 과학 학습 흥미도에 미치는 효과

강창익 ( Chang Ik Kang ),강경희 ( Kyung Hee Kang ),이상칠 ( Sang Chil Lee ) 경북대학교 과학교육연구소 2013 科學敎育硏究誌 Vol.37 No.2

이 연구의 목적은 활동 중심 STEAM 교육 프로그램을 개발하고, 이 프로그램이 학생들의 과학 학습 흥미도에 미치는 효과를 알아보기 위한 것이다. 이 프로그램은 7학년 과학반을 대상으로 적용되었다. 이 연구는 단일집단 사전사후검사 설계로 이루어졌다. 검사도구로는 과학학습 흥미도 검사지를 활용했다. 대응표본 t 검정 결과 과학 학습 흥미에 대한 사전 검사와 사후 검사 사이에는 유의미한 차이가 나타났다. 또한 학습 흥미도의 하위 영역인과학에 대한 태도, 과학학습 인식, 과학학습 전략면에서도 유의미한 차이가 나타났다. 이와 같은 결과는 STEAM 교육 프로그램이 학생들의 과학 학습 흥미도를 높이는데 효과적임을 나타낸 것이다. 따라서 앞으로 활동 중심 STEAM 교육 프로그램의 효과에 관한 연구들이 지속적으로 이루어져야할 것이다. The purposes of this study were to develop the activity based STEAM education program and to investigate the effects of the developed program on students` interest in science learning. The program was applied to 7th grade science club. This study was planned to single group pre-post test design. Test tool was the questionnaire of interest on science learning . In the results of t-test, there was statistically significant difference on the pretest and posttest of interest in science learning. Also there was significant difference on attitude toward science, recognition and strategy on science learning that were subdomains of interest on science learning. The results indicated that activity-based STEAM education program was effective in improving students` interest in science learning. In future, studies should be conducted that examine the effect of STEAM program on creativity and problem-solving activity. Therefore studies on the effectiveness of activity-based STEAM education programs should be made continuously.