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폴리피롤을 이용한 능동형 약물전달시스템의 제작 및 평가
이상조 ( Lee Sang Jo ),이승기 ( Lee Seung Gi ),박정호 ( Park Jeong Ho ) 한국센서학회 2004 센서학회지 Vol.13 No.1
N/A This paper presents drug release properties of active drug system (DDS) using volume change of polypyrrole (PPy). The incorporation of various chemical substances into the PPy and controlling its release with the externally applied voltage to the PPy are possibel. In order to confirm possibility for drug delivery system qualitatively, indicator(phenolred) was examined as a dopant of PPy. The applied voltage to the PPy electrode was set to -2 V and this negative voltage makes the anionic indicator released in saline solution. After qualitative analysis, in order to confirm quantitative drug release characteristic of PPy, salicylate which is one of the aspirin substance was used as a dopant of PPy. As a result, the salicylate release characteristics with time was thoroughly investigated while varying the electrode area, polymerization time, the applied voltage for drug release. Based on these quantitative results, a preliminary experiment was carried out to check the feasibility of the PPy applicable to the neuronal system.
이상조,이용석,고정한,Lee, Sang-Jo,Lee, Yong-Seok,Go, Jeong-Han 대한기계학회 2001 大韓機械學會論文集A Vol.25 No.8
Recent noticeable advances of CNC machine tools have considerably improved productivity and precision in manufacturing processes. However, in the respect of productivity some defects still remain because selection of machining conditions entirely depends on the experiences of programmers. Usually, machining conditions such as feed rate and spindle speed have been selected conservatively by considering the worst cases, and it has brought the loss of machining efficiency. Thus, the improvement of cutting force controller has been done to regulate cutting force constantly and to maximize feedrate simultaneously in case that machining conditions change variously. In this study, sliding mode control with boundary layer is applied to milling process for cutting force regulation and in a commercial CNC machining center data transfer between PC and PMC (programmable machine controller) of CNC machine is done using a standard interface method. And in the cutting force measurement, an indirect cutting force measuring system using current signal of AC servo is adopted in order not to use high-priced equipment like tool dynamometer. The purpose of this study is to maximize the productivity in milling process, thus its results can be applied to cases such as rough cutting process.
Effect of Mg-Sulfate and Mg-Hydroxide on Growth of Chinese Cabbage
이상조,이승호,신현진,조현종,김복진,정종배,Lee, Sang-Jo,Lee, Sung-Ho,Shin, Hyun-Jin,Cho, Hyun-Jong,Kim, Bok-Jin,Chung, Jong-Bae Korean Society of Soil Science and Fertilizer 2003 한국토양비료학회지 Vol.36 No.4
최근 고토비료로 등록된 수산화고토는 황산고토와 비교할 때 용해도가 매우 낮으며 토양반응에 미치는 영향 측면에서도 다른 특성을 가지고 있다. 본 연구에서는 이들 두 가지 고토비료를 표준시비량인 $300kg\;MgO\;ha^{-1}$ 수준으로 처리한 경산통 토양에서 배추 재배하여 그 비효를 비교하였다. 수산화고토는 배추의 엽수와 생체중을 증가시키는 효과를 보였으나, 생육 전반에 미치는 효과에 있어서는 황산고토와 비교할 때 통계적으로 유의성 있는 차이를 보이지는 않았다 ($p{\leq}0.05$). 배추의 마그네슘 함량은 생육초기에는 황산고토 처리구에서 높았으나 수확기에 조사된 결과에서는 수산화고토 처리구에서 높았으며, Ca, P, 및 K 함량은 황산고토에 비하여 수산화고토 처리구에서 높았다. 그러나 비종간의 이들 양분 흡수의 차이는 통계적으로 유의하지 못하였다. 황산고토를 처리한 토양의 pH는 대조구에 비하여 낮아졌으나, 수산화고토 처리구에서는 pH가 높아졌고 유효인산 함량 또한 증가하였다. 침출성 Ca 함량은 수산화고토 처리구에 비하여 황산고토 처리구에서 낮게 나타났다. 토양반응과 양분의 유효도에 미치는 영향의 차이는 비종간의 화학적 특성 차이에 기인하는 것으로 판단된다. 따라서 동일한 수준으로 시용할 때, 수산화고토와 황산고토의 작물에 대한 비효는 대등한 것으로 결론지을 수 있으며, 산성토양이나 용탈이 쉽게 일어날 수 있는 사질 토양에서는 산성비료이며 수용성인 황산고토보다 수산화고토의 시용이 유리할 것으로 판단된다. Magnesium hydroxide, which recently registered as a Mg fertilizer, is greatly different from magnesium sulfate in its solubility and effect on soil pH. In this study, the effects of magnesium hydroxide and magnesium sulfate on growth of chinese cabbage were compared at the application rate of $300kg\;MgO\;ha^{-1}$ in a Gyeongsan clay loam soil. Although magnesium hydroxide was effective in increasing number of leaf and fresh weight, overall effects of magnesium hydroxide and magnesium sulfate on the growth of chinese cabbage were not significantly different ($p{\leq}0.05$). Comparing the two magnesium fertilizer treatments, magnesium content of chinese cabbage was relatively higher in the magnesium sulfate treatment in the early stage of growth, but it was higher in the magnesium hydroxide treatment at harvest. Contents of Ca, P, and K in chinese cabbage were relatively higher in the magnesium hydroxide treatment than those in magnesium sulfate treatment. But, the differences in nutrient uptakes by chinese cabbage between the treatments were not significant ($p{\leq}0.05$). Therefore, magnesium hydroxide is expected to be used with nearly the same effects on crops as magnesium sulfate at the same application rate of Mg. Soil pH in the treatment of magnesium sulfate was lower than that of control treatment, but magnesium hydroxide could increase pH. Magnesium hydroxide can be used preferentially in acid and/or sandy soils, where magnesium sulfate can induce further soil acidification and leaching loss of Mg is often a severe problem.