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이드보라 ( De Bo Rah Lee ),홍순권 ( Soon Kwon Hong ),전지승 ( Ji Sung Chun ),최준희 ( Jun Hee Choi ),성호석 ( Ho Suk Sung ),황선욱 ( Seon Wook Hwang ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.4
Benign symmetric lipomatosis is a very rare disease that`s characterized by a symmetric accumulation of excessive amounts of adipocytes. The lesions are located mainly on the neck, trunk and proximal extremities. Although its etiology is unknown, it has been described to be associated with a heavy alcohol intake. A 51-year-old woman presented with a two year history of ill-defined soft masses on both mandibular areas. We made the diagnosis of benign symmetric lipomatosis according to the histopathologic examination. As a difference from other reports of benign symmetric lipomatosis, our patient was non-drinker for her past history. We present here a case of benign symmetric lipomatosis at an unusual predilection site and this developed in a non-drinker. (Korean J Dermatol 2009;47(4):456~458)
이드보라 ( De Bo Rah Lee ),이현재 ( Hyun Jae Lee ),정소영 ( So Young Jung ),서종근 ( Jong Keun Seo ),황선욱 ( Seon Wook Hwang ),성호석 ( Ho Suck Sung ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.3
Large surgical defects are often difficult to repair and extensive adjacent skin transfer may be necessary. The purse-string suture can be used to reduce the size of large defects, but a second intervention may be necessary and requires several weeks for complete healing. Therefore, reconstruction of large defects is a challenge to the dermatologist. We report a case of basal cell carcinoma on the back in which the skin defect was reconstructed by a quadripolar advancement flap. Because the large O-shaped defect resulted in an X-shaped closure, we named this flap the O-X flap. (Korean J Dermatol 2010;48(3):217~219)
김정욱 ( Jung Wook Kim ),오두진 ( Doo Jin Oh ),박정훈 ( Jeong Hoon Park ),이드보라 ( De Bo Rah Lee ),황선욱 ( Seon Wook Hwang ),박성욱 ( Sung Wook Park ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.1
Recurrent cutaneous eosinophilic vasculitis (RCEV) is a rare cutaneous disease characterized by necrotizing vasculitis of small vessels, with exclusive eosinophilic infiltration and minimal, or no leukocytoclasis. It presents with recurrent erythematous or purpuric papules or plaques, or angioedema associated with peripheral eosinophilia. This disease follows a benign chronic course without evidence of systemic involvement. Systemic corticosteroid therapy is effective but the disease commonly pursues a relapsing and remitting course. Herein, we report a case of RCEV that was effectively treated with systemic corticosteroids and dapson(R) (diaminodiphenylsulphone). Furthermore, the patient did not show a relapse of the disease in spite the tapering the systemic corticosteroid dose. (Korean J Dermatol 2007;45(1):47~50)
전신성 홍반성 루프스와 이차성 항인지질 항체 증후군 환자에서 발생한 망상 청피반
김정욱 ( Jung Wook Kim ),오두진 ( Doo Jin Oh ),조경종 ( Kyung Jong Cho ),홍순권 ( Soon Kwon Hong ),이드보라 ( De Bo Rah Lee ),황선욱 ( Seon Wook Hwang ),박성욱 ( Sung Wook Park ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.6
Antiphospholipid syndrome is defined as the presence of lupus anticoagulant antibodies or anticardiolipin antibodies with vascular thrombosis or specific pregnancy complications. Antiphospholipid syndrome can be associated with autoimmune, malignant or infectious diseases. Cutaneous manifestations of antiphospholipid syndrome are variable and can be a first clue to the syndrome or other associated diseases. We report a case of systemic lupus erythematosus and secondary antiphospholipid syndrome presenting as livedo reticularis on both legs of a patient. We recommend that patients with livedo reticularis should be examined for systemic lupus erythematosus or antiphospholipid syndrome. (Korean J Dermatol 2007;45(6):622∼625)
아토피피부염 환자의 치료경과에 따른 중증도 평가에서 SCORAD Index와 기계적 측정값과의 상관관계
황선욱 ( Seon Wook Hwang ),강주현 ( Ju Hyun Kang ),설정은 ( Jung Eun Seol ),서종근 ( Jong Keun Seo ),이드보라 ( De Bo Rah Lee ),성호석 ( Ho Suk Sung ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.4
Background: Atopic dermatitis is a chronic relapsing inflammatory skin disease characterized by dry skin, pruritus, and typical distribution of the lesions. Because an objective tool for the assessment of disease severity of atopic dermatitis has yet to be agreed upon, many dermatologists are dependent on subjective history and clinical scoring. Recently, instrumental measurements have been used for the assessment of skin barrier function. Objective: The purpose of this study was to assess the correlation between SCORAD (scoring of atopic Dermatitis) index and the results of instrumental assessments of disease severity in atopic dermatitis. Additionally, we compared the values of instrumental measurements on normal and lesional skin. Methods: From February to April 2007, 44 patients with atopic dermatitis were treated with topical steroids, topical calcineurine inhibitors, oral antihistamine agents and systemic steroids. At initial visit, and after 1, 2, 3, and 4 weeks of treatment, the SCORAD index was measured, and instrumental measurements of skin surface hydration (SSH), transepidermal water loss (TEWL), and pH were performed on the antecubital fossa (lesional skin) and flank (normal skin) of the patients by Corneometer(R), Tewameter(R), and skin-pH-meter(R). Results: Significant correlation was found between SCORAD index and SSH (p<0.0001), TEWL (p<0.0001), and pH (p=0.1680). SSH and TEWL improved within 1 week of treatment but pH improved after 2 weeks of treatment. Instrumental assessments showed lesional skin had lower SSH, higher TEWL, and more alkaline pH than normal skin. Conclusion: Instrumental measurements showed correlation with SCORAD index. Therefore, we can use instrumental assessments as well as SCORAD index in the assessment of disease severity of AD. (Korean J Dermatol 2010;48(4):266~271)
황선욱 ( Seon Wook Hwang ),홍순권 ( Soon Kwon Hong ),조경종 ( Kyung Jong Cho ),서종근 ( Jong Keun Seo ),김지연 ( Ji Yeon Kim ),성호석 ( Ho Suk Sung ),이드보라 ( De Bo Rah Lee ) 대한피부과학회 2009 大韓皮膚科學會誌 Vol.47 No.1
Herpetic whitlow is a painful cutaneous infection that occurs on the fingers and toes, and it is caused by herpes simplex virus (HSV)-1 or -2. It is correlated with the immunocompromised state of patients or with occupations that are in frequent contact with the secretions or mucous membranes infected by HSV. We present here a 29-year-old woman who was referred to our department with recurrent vesicles and ulcerative lesion of the right 3rd finger. She was immunocompetent and did not have any occupational hazard of herpetic whitlow. We made the diagnosis of herpetic whitlow by the clinical features and the histopathologic examinations. In addition, we used polymerase chain reaction assay to detect the type of HSV and we confirmed she suffered with herpetic whitlow that was caused by HSV-2. (Korean J Dermatol 2009;47(1):98~100)