유방암의 감시림프절 검사에서 유방크기와 체질량지수에 따른 검사시간 변화

이다영,남궁혁,조석원,오신현,임한상,김재삼,이창호,박훈희,Lee, Da-Young,Nam-Koong, Hyuk,Cho, Seok-Won,Oh, Shin-Hyun,Im, Han-Sang,Kim, Jae-Sam,Lee, Chang-Ho,Park, Hoon-Hee 대한핵의학기술학회 2012 핵의학 기술 Vol.16 No.2

유방암 환자의 감시림프절 생검을 위하여 현재 방사성동위원소와 blue dye를 이용한 감시림프절 매핑(Mapping)이 선행되고 있다. 현재 모든 환자에 대하여 일괄적인 검사방법이 적용되므로 환자의 유방의 크기나 비만도와 같은 특성이 고려되지 않아 림프절의 흐름이 느린 환자의 경우, 림프절을 충분히 형성하지 못한 채 검사가 종료되는 경우가 종종 발생한다. 본 연구에서는 환자의 신체적 특성인 체질량지수와 유방의 크기에 따른 림프액의 속도차이를 관찰하였다. 이를 통해 방사성동위원소를 이용한 유방의 감시림프절 신티그래피 에서 환자의 특성을 고려한 최적의 검사시간을 도출하는데 목적을 두었다. 본 연구는 2011년 10월부터 2011년 12월까지 수술직전 유방의 감시림프절 신티그래피를 시행한 100명(여성 100명, 평균연령 $50.34{\pm}10.26$)를 대상으로 하였다. 장비는 감마카메라 Forte (Philips Medical Systems, Nederland B.V.)를 사용하였으며, 방사성의약품은 $^{99m}Tc$-Phytate 18.5 MBq, 0.5 ml를 피내주사하였다. 먼저 80명의 환자를 대상으로 기존의 5분 검사방법대신 충분히 림프절을 형성할 때까지 시간의 제한 없이 영상을 획득하였다. 이를 통해 환자의 유방크기와 체질량지수 별 그룹을 나누어 평균 검사시간을 구하였다. 이 결과를 바탕으로 검사시간을 변화시킨 변형 유방 림프신티그래피를 20명의 환자에게 시행하여 유용성을 확인하였다. 80명의 대상 중 유방의 크기에 따른 평균 검사시간은 A그룹 2.48분, B그룹 7.69분, C그룹 10.43분이었다. 80명의 대상 중 체질량지수에 따른 평균 검사시간은 저 체중 1.35분, 표준 2.56분, 과 체중 5.62분, 비만 15분이었다. 앞서 얻어진 정보를 바탕으로 각 그룹별 적절한 검사시간을 적용하여 검사를 시행하였다. 결과는 20명 중 성공평가를 받은 경우는 17회 실패평가를 받은 경우는 3회로 총 85% 성공률을 나타내었다. 유방의 크기와 체질량지수에 따른 총 검사 시간은 체질량지수가 높을수록, 유방의 크기가 클수록 증가하였으며, 얻어진 정보를 바탕으로 기존 검사방법에서 검사시간만을 변화시킨 변형 유방 림프신티그래피를 적용하였을 때 대부분의 경우 검사시간 내 림프절을 형성할 수 있었다. 이를 통해 모든 환자에게 일괄적으로 적용하던 검사방법보다 개인의 신체적 특성을 고려한 적절한 검사시간을 각각 다르게 적용하였을 때 검사에서 높은 성공률을 보임을 알 수 있었다. Purpose : At this time, the sentinel lymph node mapping using radioisotope and blue dye is preceded for breast cancer patient's sentinel lymph node biopsy. But all patients were applied the same protocol without consideration of physical specific character like the breast sizes and body mass indexes. The purpose of this study is search the optimized scan time in breast sentinel lymphangiography by observing how much the body mass index and breast size influence speed of lymphatic flow. Materials and Methods : The Object of this study was 100 breast cancer patients(Female, 100 persons, average age $50.34{\pm}10.26$ years old)at Severance hospital from October 2011 to December 2011. They were scanned breast sentinel lymphangiography before operation. This study was performed on Forte dual heads gamma camera (Philips Medical Systems, Nederland B.V.). All patients were intra-dermal injected $^{99m}Tc$-Phytate 18.5 MBq, 0.5 ml. For 80 patients, we have scanned without limitation of scan time until the lymphatic flow from the lymph node since injection. We measured how long the lymphatic flow time between departures from injects site and arrival to lymph node using stopwatch. After we calculated patient's Body mass Index and classified as 4 groups. And we measured patient's breast size and classified 3 groups. The modified breast lymphangiography that changing scan time according to comparison study's result was performed on 20 patients and was estimated. Results : The mean scan time as breast size was A group 2.48 minutes, B group 7.69 minutes, C group 10.43 minutes. The mean scan time as body mass index was under weight 1.35 minutes, normal weight 2.56 minutes, slightly over 5.62 minutes, over weighted 5.62 minutes. The success rate of modified breast lymphangiography was 85%. Conclusion : As the Body mass index became higher and breast size became bigger, the total scan time is increased. Based on the obtained information, we designed modified breast lymphangiography protocol. At the cases applying that protocol, most of sentinel lymph nodes were visualized as lymphatic pool. In conclusion, we found that the more success rate in modified protocol considering physical individuality than study carrying out in the same protocol.

화학, 생물, 방사능 사고의 정신적 영향

이다영,심민영,Lee, Da Young,Sim, Minyoung 대한불안의학회 2017 대한불안의학회지 Vol.13 No.1

We reviewed the scientific literature on psychological effects of Chemical, Biological, Radiological, Nuclear, Explosive (CBRNE) disaster, which is one of the biggest threat to modern society. CBRNE disaster has the potential to cause specific physical symptoms and psychological distress in victims ; moreover, various toxic symptoms and carcinogenesis/mutation would be an important issue. Bioterrorism can cause localized outbreaks of infectious disease or pandemic disaster. Somatization as well as posttraumatic stress symptoms and depression are the characteristic psychological symptoms in CBRNE disaster's victims. CBRNE disasters could lead to large-scale public fear and social chaos due to the difficulties involved in verifying the extent of exposure and unfamiliar area to the common people. In the evacuation process, problems associated with adjustment and conflict between victims and residents should be considered.

홍삼·복분자 혼합 발효물을 첨가한 치즈의 항비만 효과

이다영,김남석,김하림,김민선,이창현,오미진,오찬호,김종석,김명순,권진,Lee, Da young,Kim, Nam Seok,Kim, Ha Rim,Kim, Min Sun,Lee, Chang Hyun,Oh, Mi Jin,Oh, Chan Ho,Kim, Jong Suk,Kim, Myung Soon,Kwon, Jin 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.2

This study was investigating the anti-obesity effects of diets with a mixture of cheese, red ginseng and fermented mature fruit of Rubus coreanus Miquel. We fed the experimental diets (SC5, SC10) supplemented with 5% or 10% cheese containing of fermented mixture, then orally administered the extract of fermented mixture (RB100, RB300) at a concentration of 100 or 300 mg/kg body weight to SD rats with high fat diet (HFD). The results were as follows: Sample cheese groups decreased visceral fat mass and adipocyte size of stomach compared to that of HFD group. Additionally, lipid droplets of liver in sample cheese groups were smaller than that in HFD group. The serum triglyceride (TG), total cholesterol (tChol), glucose, leptin, and insulin levels in sample cheese group were lower than that in HFD group. But, the serum adiponectin and HDL-cholesterol (cHDL) levels were higher than that in HFD group. These results suggest that fermentation of red ginseng and Rubus coreanus mixed with cheese might be helpful in preventing obesity in high fat diet-fed rats.

20대 소비자의 기초화장품 구매 전 이용한 정보원천 활용도에 따른 구매 후 만족도

이다영 ( Da Young Lee ),이승신 ( Seung Sin Lee ),이영희 ( Young Hee Lee ) 대한가정학회 2017 Human Ecology Research(HER) Vol.55 No.6

Cosmetics market information is important due to advances in information communication technology and the growth of cosmetics market. This study analyzed the relationship between the pre-purchase utilization of information (commercial, neutral, personal and experiential) and the post-purchase satisfaction of skin care cosmetics, categorized as functionality, safety, economic feasibility, information reliability, purchase convenience, condition of purchase place, packaging/design of product and service. This study analyzed reliability, frequency, differences, correlation and regression analysis using SPSS ver. 24.0. The study results are summarized as follows. First, gender was a significant variable in the level of information source utilization. Women used commercial, neutral, and experiential information sources more actively than men. However, women had lower post-purchase satisfaction that could be understood through expectation disconfirmation theory. Women have very high expectations that can lower post-purchase satisfaction. Second, information source utilization can improve post-purchase satisfaction for cosmetics. The consumer post-purchase satisfact the lowest in the commercial information source; however, consumers were satisfied when the commercial informationinformation sourceenon and regre. Third, the consumeried itnformation sourceenon and regression analysis ial, neutral,source and reflected the characteristics of experiential goods. Therefore, companies should provide accurate commercial, personal and experiential information to increase consumervide accurate commercial, per as well as conduct experiential marketing

채팅 메시지 구성을 활용한 메신저 특성 분석

이다영(Da-Young Lee),조환규(Hwan-Gue Cho) 한국정보과학회 2022 한국정보과학회 학술발표논문집 Vol.2022 No.06

소셜커머스 카테고리 배열방식과 GUI에 따른 소비자 충성도

이다영(Lee, Da Young),이혁재(Lee, hurk Jae),김승인(Kim, Seung In) 한국디지털디자인협의회 2014 (사)한국디지털디자인협의회 conference Vol.2014 No.5

학교 기반 정신건강증진 및 학교폭력 예방 프로그램 단기적 실시의 효과에 대한 예비연구

이다영(Da-Young Lee),노은미(Eun-Mi Roh),김인영(In-Young Kim),고귀녀(Guy-Nueo Ko),최정원(Jung-Won Choi),이영렬(Young-Ryeol Lee),김예니(Yeni Kim) 대한소아청소년정신의학회 2014 소아청소년정신의학 Vol.25 No.4

Objectives:The purpose of this study is to evaluate the preliminary effects of school-based short term mental health awareness and school bullying prevention programs. Methods:From April to December 2013, the Child and Adolescent Mental Health Promotion team of Seoul National Hospital conducted school-based short term social skill training (N=56, 4 sessions), mental health awareness (N=84, 4 sessions) and school bullying prevention programs (N=171, 1 session) in elementary and junior high schools located in Seoul. The changes in the subjects before and after the program were assessed. Results:The a social skills training program improved the ‘helping’ behaviors in boys (t=-2.355, p<.05) and ‘sharing’ (t=-3.223, p<.01), ‘cooperation’ (t=-2.235, p<.05), and ‘comforting’ (t=-2.830, p<.01) behaviors in girls, assessed using the Prosocial Behavior Questionnaire. The mental health awareness program improved ‘general health awareness’ (t=2.620, p<.05), measured using the Korean General Health Questionnaire. The school bullying prevention program resulted in decreased ‘self esteem’ (t=3.769, p<.01), measured using the Self Esteem Scale and decreased ‘anger’ (t=4.198, p<.01), assessed using the Novaco Anger Scale. Conclusion:The results of our preliminary analysis suggest that school-based mental health awareness and school bullying prevention programs may be effective even when conducted for a short term. Future investigation is necessary in order to validate the long term effects of these programs.

우주선 : 발달장애 아동의 소근육 발달을 위한 음악치료 에듀테인먼트 서비스

이다영(Lee, Da Young),윤재영(Yun, Jae Young) 한국디자인학회 2017 한국디자인학회 학술발표대회 논문집 Vol.2016 No.10

노후공업지역의 노후 건축물과 음식업의 상권 분포 특성 분석 - 문래동을 중심으로 -

이다영(Lee, Da-Young),이현수(Lee, Hyunsoo),이진국(Lee, Jin-Kook) 한국실내디자인학회 2022 한국실내디자인학회 학술대회논문집 Vol.24 No.3

산업도금폐수 처리에 사용된 탄소폼 흡착소재의 중금속 탈착 및 회수에 관한 연구

이다영(Da-Young Lee),이창구(Chang-Gu Lee),김대운(Dae-Woon Kim),박상현(Sang-Hyen Park),권지향(Ji-Hyang Kweon),이상협(Sang-Hyup Lee) 대한환경공학회 2016 대한환경공학회지 Vol.38 No.11

본 연구에서는 탄소폼 흡착소재를 이용하여 산업도금폐수로부터 중금속을 흡착 제거한 후 탈착용액을 이용하여 제거된 중금속을 용출하고 회수하는 과정의 특성을 평가해 보고자 하였다. 용액의 조성에 따른 복합 중금속의 탈착 특성을 살펴본 결과 증류수 조건에서는 용출이 관측되지 않았으며, 탈착용액으로 HCl과 H₂SO₄를 이용한 경우 높은 중금속 농도를 나타내었다. 탈착 용액을 이용함과 더불어 물리적 기술인 초음파 처리를 이용한 경우 중금속의 용출이 증진되는 것을 확인하였으며, 초음파 장치의 출력이 높고 반응 시간이 길수록 효율도 증가하는 것으로 나타났다. 탄소폼 흡착소재를 구리도금 세척수 처리에 적용시켜본 결과 200 반응기부피(Bed volume) 동안 안정적인 제거 성능을 나타내었으며, 흡착된 구리는 탈착용액을 이용하여 용출시킨 후 직류 전원 장치를 이용하여 회수할 수 있었다. 또한 구리가 회수된 탈착용액은 재이용 효율은 84.2%로 나타났다. We investigated the characteristics of heavy metal desorption and recovery from carbon foam after plating wastewater treatment. The heavy metal desorption depends on solution chemistry because desorption occurred in HCl and H₂SO₄ solution but did not occur in distilled water. Heavy metal desorption efficiency was increased using ultrasonication with desorption solution. The higher ultrasonic power and the longer reaction time improve efficiency. The copper plating rinse solution was treated reliably by carbon foam adsorbent during 200 bed volume. The adsorbed copper was dissolved using desorption solution and recovered by DC power supply. After copper recovery, the reuse efficiency of desorption solution was 84.2%.