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오경진 ( Kyung Jin Oh ),이기병 ( Ki Byung Lee ),홍순원 ( Soon Won Hong ),정교태 ( Kyo Tae Jung ),최홍규 ( Hong Kyu Choi ),김형중 ( Hyung Jung Kim ),안철민 ( Chul Min Ahn ),장윤수 ( Yoon Soo Chang ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.5
Malignant rhabdoid tumors arise primarily from the kidney. Extrarenal malignant rhabdoid tumors are rare, with the liver, central nervous system, and skin reported as the primary sites. Malignant rhabdoid tumors of the mediastinum are extremely rare among extrarenal malignant rhadoid tumors; only 3 cases have been reported to date, all characterized by aggressive clinical behavior. We experienced a 35-year-old woman diagnosed with malignant rhabdoid tumor in the anterior mediastinum with multiple metastases. The tumor was surgically unresectable, and treated with palliative radiation therapy. Three-month after radiation treatment, she died from dissemination of the malignant rabdoid tumor.
증례 : 소화기 ; 내시경적 보툴리눔 독소 주입으로 치료한 윤상인두근이상증 1예
정교태 ( Kyo Tae Jung ),최홍규 ( Hong Kyu Choi ),이기병 ( Ki Byung Lee ),유정환 ( Jung Hwan Yu ),김지현 ( Jie Hyun Kim ),박윤길 ( Yoon Ghil Park ),이상인 ( Sang In Lee ) 대한내과학회 2010 대한내과학회지 Vol.79 No.3
보툴리눔 독소는 아칼라지아, 당뇨병성 위마비, 오디괄약근 장애, 만성 항문치열 등 다양한 소화기 질환에 사용되고 있다. 윤상인두근 기능이상은 이전에는 기계적 풍선 확장술이나 윤상인두근 절제술로 치료하였으나, 최근 윤상인두근 내 보툴리눔 독소 주입에 의해 안전하고 효과적으로 치료될 수 있음이 보고되고 있다. 본 환자는 뇌졸중에 의한 윤상인 두근 장애로 연하곤란을 호소하였으며, 내시경적 보툴리눔 독소주입 이후 호전을 보였기에 이를 보고하는 바이다. Botulinum toxin has been used to treat various gastrointestinal tract diseases such as achalasia, diabetic gastroparesis, sphincter of oddi dysfunction, and chronic anal fissures. Recently, it has also been used for the treatment of cricopharyngeal muscle dysfunction. Several studies have reported that botulinum toxin injections may be a safe and effective treatment. Previously, cricopharyngeal muscle dysfunction was treated by mechanical balloon dilation or cricopharyngeal myotomy. Here, we report a case of a 57-year-old man who presented with cricopharyngeal dysphagia due to cerebral infarction and who was successfully treated with endoscopic botulinum toxin injection. (Korean J Med 79:301-305, 2010)
자가 면역성 갑상선염 환자에서 발생한 쇼그렌 증후군과 원위 세뇨관 산증 1예
안혜림 ( Hye Rim An ),배성창 ( Sung Chang Bae ),이기병 ( Ki Byung Lee ),이용규 ( Yong Kyu Lee ),김좌경 ( Jwa Kyung Kim ),박형천 ( Hyeong Cheon Park ),하성규 ( Sung Kyu Ha ),이정은 ( Jung Eun Lee ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.1
A 52-year old woman, who had hypothyroidism associated with autoimmune thyroiditis for 5 years, was hospitalized for tingling sensation and muscle weakness of both lower extremities. Her initial laboratory findings showed severe hypokalemia, metabolic acidosis, and high titer of thyroid autoimmune antibodies. She was diagnosed of distal renal tubular acidosis by bicarbonate loading test (FEHCO3-<3.0%) and renal calcifications on pre-enhanced CT scan. Since she had other symptoms of xerostomia and xerophthalmia, primary Sjogren`s syndrome was diagnosed by Schirmer test, salivary scan, and serologic findings. She was treated with potassium citrate, potassium chloride, and hydroxychlorquine. Four months later, she has remained well with those treatments. There were only a few case reports about distal renal tubular acidosis associated with Sjogren`s syndrome and autoimmune thyroiditis. In Korea, there has not been any report of such cases. Therefore, we report a case of distal renal tubular acidosis and Sjogren`s syndrome in a patient with autoimmune thyroiditis.