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열간 조압연 공정에서 자동차 외판재용 강판의 소성변형거동 예측
정재환(J. H. Jeong),이경훈(K. H. Lee),이상호(S. H. Lee),김형진(H. J. Kim),임종협(J. H. Lim),이계영(K. Y. Lee),김병민(B. M. Kim) 한국소성가공학회 2012 한국소성가공학회 학술대회 논문집 Vol.2012 No.10
The aim of this study is to predict the plastic deformation behavior of automotive steel sheet during the hot rolling process. Material tracking technique was used to investigate material movement during hot rolling operation. Hot compression test is performed to obtain the effective stress-strain curve of initial slab, which is applied to FE-simulation. Tracked points of slab were calculated at each rolling stage such as sizing press and rough rolling process. FE-simulation results were compared with measured track points of rolled bar in the real hot rolling mill. FEA using material tracking technique is a suitable method for the prediction of the slab metal flow during the hot rolling process.
Pemetrexed/cisplatin 병합 2차 항암화학요법에 극적 반응을 보인 악성 흉막 중피종
이승민 ( Seung Min Lee ),고순영 ( Soon Young Ko ),서태호 ( Tae Ho Seo ),이정현 ( Jung Hyun Lee ),최승오 ( Seung Oh Choi ),이정근 ( Jeong Geun Lee ),김완섭 ( Wan Seop Kim ),이태훈 ( Tae Hoon Lee ),유광하 ( Gwang Ha Yoo ),이계영 ( K 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.62 No.5
Malignant pleural mesothelioma (MPM) is a rare tumor that is difficult to clearly distinguish from an adenocarcinoma but usually has a poor prognosis. Numerous cytotoxic agents have been used in the primary treatment of MPM with limited success. A complete response is unusual and a partial response occurs in less than one-third of patients. Recently, a phase III trial showed that a combination of pemetrexed with cisplatin resulted in a significantly higher response rate and median survival time than with cisplatin alone. We encountered a case of a dramatic tumor response to pemetrexed/cisplatin combination chemotherapy in patients with MPM, which was resistant to the 1st-line gemcitabine/cisplatin therapy. After six cycles of pemetrexed/cisplatin combination chemotherapy, the tumor volume had decreased dramatically with complete symptom relief. There was no chemotherapy-related toxicity or scheduled violation. The patient is under maintenance chemotherapy with the same regimen. (Tuberc Respir Dis 2007; 62: 432-436)