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윤숙정 ( Sook Jung Yun ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
A 10-month-old baby presented with brownish to orange colored papules and plaques of the face. The lesion started from the face at 6 months old and spread. Physical examination revealed brownish to yellowish orange-colored plaques at symmetric distribution on the both cheeks and eyelids. There were also scattered yellowish papules on the face and scalp. The trunk and extremities showed similar scattered papules, and a few confluent palques. Histologic evaluation revealed granulomatous infiltrates with some giant cells, macrophages, lymphocytes, and eosinophils. Immunohistochemical stains including CD68, S100 and CD1a were performed. What is your diagnosis?
Skin tumors that dermatologists should know
윤숙정 ( Sook Jung Yun ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
As a dermatologist, all of us should know skin tumors. Especially, we should not mis-diagnose malignant skin tumors. However, in reality, there are lots of skin cancers that mimicking benign skin tumors or inflammatory skin diseases. In this talk, I want to show various interesting skin cancers that dermatologists should know. In addition, I will introduce various benign mimickers of each skin cancers. Epidermal skin cancers Actinic keratosis Squamous cell carcinoma in situ, Bowen’s disease Squamous cell carcinoma, Verrucous carcinoma Basal cell carcinoma Melanoma Skin appendage tumors Eccrine and apocrine tumors Sebaceous tumors Paget’s disease and extramammary Paget’s disease Mycosis fungoides and Lymphoma Leiomyosarcoma Kaposi’s sarcoma Angiosarcoma Dermatofibrosarcoma protuberans Metastatic carcinoma
Hydroxyurea 장기복용 환자에서 발생한 광범위한 피부궤양과 편평세포암
윤숙정 ( Sook Jung Yun ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.4
Hydroxyurea, one of conventional chemotherapies in chronic myelogenous leukemia(CML) and polycythemia vera inhibits ribonucleotide reductase, which catalyzes the rate-limiting step in the de novo synthesis of deoxynucleotide triphosphates required for DNA synthesis. Various cutaneous side effects due to hydroxyurea have been reported as follows alopecia, diffuse hyperpigmentation, scaling, poikiloderma, atrophy of the skin and subcutaneous tissues, nail changes with multiple pigmented nail bands or brittleness, erythema and scaling of acral sites simulating chronic dermatomyositis, lichen plans-like lesions, or skin tumors on the UV-light exposed areas. A 72-year-old woman, receiving hydroxyurea for CML during 5 years, revealed hydroxyurea dermopathy such as scaly papules, poikilodermatous patches, and acral ulceration, and unusually developed squamous cell carcinoma. This is a rare case of hydroxyurea dermopathy, and the first case of squamous cell carcinoma by hydroxyurear in Korea.
Skin cancer: long-term management strategy for difficult patients
윤숙정 ( Sook Jung Yun ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2
Which skin cancer is the most difficult in terms of long-term management? Because most skin cancers are just widely excised, and that is the cure, except some invasive melanomas and other rare cancers. Among them, in this presentation, I will present a difficult extramammary Paget’s disease (EMPD) patient and review recent therapies on EMPD and present some patients from my experience. Then, I want to suggest long-term management strategy of EMPD.