여성 우울증 입원 환자에서 폐경 여부에 따른 인지기능의 차이

유지영,민정아,전양환,한상익,박이진,You, Ji-Young,Min, Jung-Ah,Jeon, Yang-Whan,Han, Sang-Ick,Park, E-Jin 대한생물정신의학회 2016 생물정신의학 Vol.23 No.4

Objectives Although forgetfulness is a common complaint among menopausal depressed women, there is still a debate about the relationship between memory impairment and menopause. The aim of this study is to examine whether menopause is related to cognitive decline among women with depressive disorders. We hypothesized that postmenopausal depressed women show generally poorer performance than premenopausal depressed women on various cognitive function tests. Methods With a retrospective chart review, we identified a total of 87 female patients (45 premenopausal patients and 42 postmenopausal patients) who were hospitalized with depressive disorders from 2000 to 2016. Demographic and clinical variables and cognitive test results were compared between two groups. Results Education year is longer in premenopausal group than postmenopausal group whereas clinical characteristics (illness duration, recurrence, and symptom severity) and mean Intelligence Quotient (IQ) were similar between two groups. The postmenopausal group took longer time for Bender-Gestalt Test (BGT) recall, Trail Making Test (TMT)-A, and TMT-B than the premenopausal group. After controlling for age and education, significant difference was remained for BGT recall (p = 0.029). Conclusions Postmenopausal state may be related with decline of visuospatial memory function, in particular, among depressed female patients. Other areas of cognitive function including complex attention, verbal memory, auditory memory, and working memory might be interpreted while considering age and education level.

조선후기 手本의 한 연구 : 慶州 驪州李氏 癡菴宗宅 소장 고문서를 중심으로

유지영(You Ji-young) 한국학중앙연구원 2005 장서각 Vol.0 No.14

In this thesis, I reviewed the document called 'Su-bon(手本)' which has never been introduced. There are many kinds of Su-bon, meanwhile we have known them as official document. But I would try to give another type of Su-bon a term of 'Sojihyung Su-bon (所志型 手本)' that have similar shapes of 'Soji(所志)' which had been submitted a petition to a local government. And looking into Su-bon, I studied what it had forms, contents, writings, processes of disposition. After through out all these analysis, I could reach the several conclusions below. First. Writers of Su-bon were peoples, servants, officials of the smallest unit of the administrative organization(ex. 風?, 上任, 洞任 etc.) When they submitted Su-bon, there were not in the name of an individual but a joint signature at least four persons. Second. Forms of Su-bon were similar to a kinds of 'So-ji' which had been submitted a petition to a local government. Besides a 'So-ji' of the most similar to 'Deong-jang(等狀, a petition which had been submitted to official government in many people's signatures), nothing but just replace Su-bon with So-ji. Third. The measuring organization of Su-bon were the competent authorities (本官) and Royal secret inspector(暗行御史). In spite of a same content of petition, submitted to the provincial authorities(監司), not written as Su-bon but Ui-song(議送, a petition which had been submitted to the provincial authorities) Forth. The contents of Su-bon were not concerned with personal dispute but a tax . Especially that was something to do with the tax which have relation to a local society's interests. Fifth. Based on forth, the matter was concerned with official affairs. So in the process of handling the matter, the government office should have intervened in it eagerly. According to the conclusion above, we can know another side of Su-bon which have a different style except for the side of Su-bon as 'a public report'. Generally there were many kinds of written petition, just like a group of So-ji (所志類), for instance So-ji(所志), Bal-gwal(白活, this is pronounced natively in Korea), Dan-ja(單子), Sang-seo(上書) and exceptionally in addition to another document, called 'Su-bon' that have never ever been known to.

한국과 미국, 독일의 초임교사 교육에 관한 비교연구

유지영 ( Ji Young You ) 충남대학교 교육연구소 2010 교육연구논총 Vol.31 No.1

초임교사는 직전 교육을 받고 교육 현장에 투입된 후 많은 어려움에 직면해 있으며 전문성 신장에도 어려움을 겪고 있다. 이에 본 연구는 우수한 초임교사를 확보하기 위해 평가라는 제도적 장치를 통하여 초임교사의 자격 기준을 강화하는 미국과 학교 현장을 중심으로 초임교사의 전문성을 체계적으로 개발하고 실행하는 독일을 대상으로 두드러진 특징들을 고찰하여 한국의 초임교사 교육에 도움이 될 만한 시사점을 발견하는 데 그 목적이 있다. 본 연구를 통해 얻은 결론은 다음과 같다. 첫째, 미국의 초임교사 교육은 학생들의 학습 결과를 향상시키는 일환으로 교사들의 자격 기준을 강화하고, 초임교사가 갖추어야 할 10가지 기준을 제시하여 초임교사 교육을 통해 전문성 신장을 유도하고 있다. 둘째, 독일의 초임교사 교육은 두 차례에 걸친 국가시험과 그 사이에 존재하는 수습 근무 기간을 두어 현장 중심 교육을 강화하여 교원의 질을 제고하고자 노력하고 있다. 이에 우리나라의 초임교사 교육은 교사 자격 기준을 정하여 평가하거나 초임교사가 당면한 가장 큰 문제인 교육현장에서의 교직수행 능력을 향상시키는 방안으로 현장 중심의 교육을 강화해야 할 것이다. The Purpose of this study was to find some suggestions to improve beginning teacher education for the beginning teachers at the elementary through a comparative study of three countries, Korea, United States of America, Germany, focused on their beginning teacher education. In this study, available data and literatures about beginning teacher education were gathered and analysed. In U.S.A, beginning teacher education based on ten standards of teacher certification, which beginning teachers have, leads to improve beginning teacher`s Professionality. In Germany, teacher education focused on the field is reinforced by two step state exam and internship between state exam. These are main difference of teacher certification system in Korea, which the 2nd class regular teacher, who is beginning teacher, becomes the 1st class regular teacher through the qualification training. Therefore, to improve the beginning teacher`s Professionality, teacher`s certification should be made and teacher education focused on the field should be reinforced.

메틸렌 블루

유지영 ( Ji Young You ) 대한임상독성학회 2010 대한임상독성학회지 Vol.8 No.1

Methylene blue is a very effective reducer of drug-induced methemoglobinemia. It has dose-dependent oxidation or reduction properties. In most cases, a dose of 1 to 2 mg/kg IV given over 5 minutes and immediately followed by a 15- to 30-mL fluid flush to minimize the local pain is both effective and relatively safe. The onset of action is quite rapid, and the effects are usually seen within 30 minutes. The dose may be repeated after 30 to 60 minutes and then every 2 to 4 hours as needed. The total dose should not exceed 7 mg/kg as a single dose or 15 mg/kg within 24 hours. Repeated treatment may be needed for treating compounds that have prolonged elimination or those compounds that undergo enterohepatic recirculation (e.g., dapsone). Methylene blue can cause dose-related toxicity. At high doses, methylene blue can also induce an acute hemolytic anemia and rebound methemoglobinemia. The reasons for treatment failure with methylene blue include ineffective GI decontamination, the existence of other forms of hemoglobin (e.g., sulfhemoglobin), a low or high dose of methylene blue and the toxicokinetics of some agents, such as aniline, benzocaine or dapsone.

학령전기 소아외상 환자의 연령별 비교 연구

유지영 ( Ji Young You ),이재일 ( Jae Il Lee ),유지영 ( Ji Yeong Ryu ) 대한외상학회 2004 大韓外傷學會誌 Vol.17 No.2

Background: Trauma is a leading cause of morbidity and mortality for children. This study was conducted to describe the characteristics of pediatric trauma and to compare the differences of two groups based on age. Methods: We performed a retrospective analysis of pediatric patients under 7 years of age admitted to our emergency department after a trauma from January 2003 through June 2003. The patients were divided into two groups based on age: group A (infant/toddlers, 0~3 years) and group B (preschool children, 4~6 years). Results: The most common cause of trauma was slip down in both groups. Fall down and burn were more frequent in group A, automobile and bicycle accident were more frequent in group B(p=0.000). The most common place of trauma was house in both groups, but other places were more frequent in group B(p=0.000). The most common trauma related device was furniture/electronics in group A, sporting goods in group B(p=0.002). Conclusions: From this study, we found statistically significant differences between the groups. Knowledge of age-related characteristics could result in improved diagnosis, treatment, and prevention of these injuries.

조선시대 임명관련 교지의 문서형식

유지영 ( Ji Young You ) 한국고문서학회 2007 古文書硏究 Vol.30 No.-

T1-2 림프절 음성 삼중음성유방암의 예후인자

유지영 ( Ji Young You ),이혜윤 ( Hye Yoon Lee ),이은숙 ( Eun Sook Lee ),배정원 ( Jeoung Won Bae ),우상욱 ( Sang Uk Woo ),박경화 ( Kyong Hwa Park ) 대한임상종양학회 2011 Korean Journal of Clinical Oncology Vol.7 No.2

배경: 삼중음성유방암은 비삼중음성유방암군에 비해 조기라 해도 더 나쁜 예후를 보이는 걸로 알려져 있다. 따라서 삼중음성유방암의 초기 치료를 위해서 정확한 예후인자를 찾는 것이 중요하다. 본 연구에서는, T1-2 림프절 음성인 삼중음성유방암의 나쁜 예후와 관련된 예후인자를 찾아 보고자 하였다. 방법: 1995년부터 2006년까지 고려대학교 의료원 안암병원에서 유방암으로 근치절제술을 시행받은 환자 중 림프절 전이나 원격전이가 없는 환자를 대상으로 하였다. 이 중에서 호르몬 수용체 및 HER2 수용체 여부에 대한 기록이 있는 환자들만을 포함시켰다. 의무기록의 후향적 분석을 통해 삼중음성유방암 및 비삼중음성유방암 환자들의 임상병리적 특징이 분석되었다. 결과: 79명 (22.9%) 의 환자들이 삼중음성유방암군으로 분류되었다. 삼중음성유방암군에서 p53 양성 환자군에서 p53 음성 환자군보다 더 낮은 무병생존율을 보였다 (p=0.028). 다변량 회귀분석에서는 35세 이하의 낮은 연령이 삼중음성유방암과 관련된 독립적인 예후인자로 나타났으며, Ki-67은 단변량 회귀분석에서 삼중음성유방암과 통계적으로 유의하게 관련성을 보였다. 결론: 본 연구에서, T1-2 림프절 음성인 삼중음성유방암에서 연령은 독립적인 예후인자이고 어릴수록 나쁜 예후와 연관됨을 알 수 있었고, Ki-67 은 통계적으로 증명되지는 않았지만, 삼중음성유방암의 예후인자가 될 수 있을 것으로 생각된다. Purpose Triple-negative breast cancer typically results in poorer prognoses compared to non-triple negative breast cancer, even in early stages. The initial management of triple negative breast cancer patients and detection of clear prognostic factors are therefore of great importance. We aimed to identify specific prognostic factors associated with unfavorable outcomes of triple negative breast cancer in T1-2 node-negative breast cancer. Materials and Methods We analyzed breast cancer patients without lymph node metastasis or distant metastasis who underwent curative surgery at the Anam Hospital of the Korea University Medical Center between 1995 and 2006. Among them, patients were eligible for analysis, only if the reports about hormone receptor and human epidermal growth factor receptor-2 status were available. Clinico-pathological features were reviewed by retrospective examination and comparison of medical records of triple negative breast cancer and non-triple negative breast cancer patients. Results Seventy-nine patients (22.9%) were categorized to the triple negative breast cancer group. The disease-free survival rate of TNBC p53-positive patients was significantly lower than that of p53-negative patients (p =0.028). In multivariate analysis, young age was an independent prognostic factor for disease-free survival of the triple negative breast cancer group. High Ki-67 expression was a significant prognostic factor in univariate analysis in triple negative breast cancer, but it was not significant in multivariate analysis. Conclusion We suggest that age is an independent prognostic factor of triple negative breast cancer in T1-2 and node-negative patients and that Ki-67 could also be a prognostic factor in these patients.

건강 보조 식품의 중독학적 관점에서의 고찰 글루코사민, 키토산

유지영 ( Ji Young You ) 대한임상독성학회 2011 대한임상독성학회지 Vol.9 No.1

Recently, westernized diet and lifestyles have led to obesity and various adult diseases resulting in a negative influence on the quality of life. There has been an increased interest in choosing proper diet and regular exercise in order to lead a healthy life. The number of people looking for dietary supplements has increased steadily. Dietary supplements are products intended to help maintain or improve the health of consumers. However, if customers take dietary supplements excessively, they may be harmful due to side effects, misuse, abuse and overdose. I performed a toxicologic review of the dietary supplements, glucosamine and chitosan, which are widely used in the country in order to provide the proper understanding of safety of these products.

갑상선 수술의 수술 중 신경모니터링의 적용에 관한 최신지견

유지영 ( Ji Young You ),김훈엽 ( Hoon Yub Kim ) 대한갑상선학회 2021 International Journal of Thyroidology Vol.14 No.1

Intraoperative neuromonitoring is a well-established method used to prevent intraoperative nerve damage, and many studies have been performed in thyroid surgery. We introduced the basic concept and practical application of intraoperative neuromonitoring, as well as its standardized techniques and detailed contents. In addition, the contents of this still yet relatively unknown field, such as its application in transoral robotic thyroidectomy and its application to the external branches of the superior laryngeal nerve, were summarized by referring to many previous studies.

음악치료 기법을 활용한 프로그램이 ADHD 아동의 문제행동 개선과 사회기술향상에 미치는 효과

유지영 ( Ji Young You ),김춘경 ( Choon Kyung Kim ) 한국정서.행동장애아교육학회(구.한국정서학습장애아교육학회) 2008 정서ㆍ행동장애연구 Vol.24 No.2