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정호영,서보영,유완식 대한소화기학회 2000 대한소화기학회지 Vol.36 No.5
Background/Aims: There is a significant weight change in most gastric cancer patients during the perioperative period. We studied the influence of perioperative body weight changes on the prognosis of gastric cancer patients. Methods: Eight hundred and forty-nine patients with gastric cancer underwent surgery between 1991 and 1995. Among them, 449 patient have lived for more than 5 years (survived group) and 400 died within 5 years, postoperatively (deceased group). We compared the perioperative body weight changes and prognosis of patients between the two groups. Results: Preoperative weight loss of the survived group was less than that of the deceased group (p$lt;0.001). In patients who underwent curative surgery, preoperative relative body weight of the survived group was 104.0±13.8% and that of the deceased group was 100.8±14.3% (p=0.001). After curative surgery, five-year survival rate of the patients whose preoperative relative body weight was above 90% was 75.9% and 5 year survival rate of the patients ose preoperative relative body weight was below 90% was 64.7% (p=0.0118). Conclusions: In gastric cancer patients who lose less weight preoperatively and maintain good relative body weight, the prognosis is good. Postoperative weight change has no influence on the prognosis.