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유승영 ( Seung Young Yu ) 경희대학교 경희의료원 2015 慶熙醫學 Vol.30 No.1
Age-related macular degeneration (AMD) is a deterioration of the central portion of the retina which facilitate central vision and permit high-resolution visual acuity. AMD is the third cause of irreversible severe visual loss in the gobal people and the prevalence of AMD has increased in Korea, according to increase a population of older age. AMD can be classified into early and late stages. The early stage is associated with minimal visual impairment and is characterized by large drusen and pigmentary abnormalities in the macula. There are two forms of late age-related macular degeneration: the atrophic form and the neovascular, exudative form. Accurate diagnosis combines clinical examination and investigations, including retinal photography, angiography, and optical coherence tomography. There is currently no completely cure for macular degeneration, but treatments may prevent severe vision loss or slow the progression of the disease considerably. Recently, intravitreal treatment with humanised monoclonal antibodies against vascular endothelial growth factor is used to ameliorate the acute manifestations of neovascular age related macular degeneration. In its earliest stages, people may not be aware they have macular degeneration until they notice slight changes in their vision or until it is detected during an eye exam. While there is little that can be done to improve the eyesight of someone who has AMD, with early detection, the rate of vision loss can be slowed. The important things to provide against AMD are to understand macular degeneration, monitor the symptoms and visit hospital regularly to test the vision.
당뇨황반부종의 종류에 따른 트리암시놀론 안내주입술의 임상분석
김영균,유승영,곽형우,Young Gun Kim,Seung Young Yu,Hyung Woo Kwak 대한안과학회 2005 대한안과학회지 Vol.46 No.1
Purpose: To determine if intravitreal injection of triamcinolone acetonide (IVTA) is effective for diabetic macular edema according to the type of macular edema. Methods: This prospective, clinical series study was carried out on 31 eyes with diabetic macular edema, which had received an intravitreal injection of 4 mg of triamcinolone acetonide. We analyzed the visual acuity and foveal thickness at post-treatment 1 week, 1, 3, and 6 months according to the type of diabetic macular edema by optical coherence tomography (OCT). Results: OCT showed 3 patterns of macular edema: cystoid type (18 eyes), sponge type (7 eyes), and serous detachment type (6 eyes). Visual acuity and foveal thickness improved in all patients. The cystoid types of macular edema show better response than the other types in visual acuity and foveal thickness. Conclusions: IVTA is a good therapeutic options for diabetic macular edema. IVTA is more effective in cystoid macular edema. Furthermore, study with more patients and focal laser treatment according to the type of macular edema may be necessary for further evaluation.
신재호,유승영,곽형우.Jae Ho Shin. M.D.. Seung Young Yu. M.D.. Hyung Woo Kwak. M.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.3
Purpose: To analyze the hyperacuity defects of preferential hyperacuity perimeter (PHP) in myopic CNV and correlate with the other macular anatomical or physiological properties obtained with fluorescein angiography (FA), Optical coherence Tomography (OCT), and central perimeter. Methods: Seven patients with myopic CNV diagnosed by FA underwent PHP, OCT, central visual field (VF). We examined the locational correlation among FA, central VF and PHP hyperacuity defect and then compared PHP hyperacuity defect with the CNV size by OCT. Also we made a comparison with macular sensitivity change in VF and hyperacuity defects change in PHP after PDT in 4 patients. Results: All the 7 eyes with myopic CNV tested positive for hyperacuity defects. 5 eyes showed locational correlation among PHP and FA, central VF. The size of hyperacuity defect of PHP and CNV size by OCT was positive correlation (p=0.007). Four eyes treated with PDT showed decrease of PHP hyperacuity defect size and changes in location according to decrease of CNV size after PDT. Conclusions: Our results suggest that the PHP may be used to detect myopic CNV and beneficial for analyzing functional effect following PDT in myopic CNV patients. These results require further validation in a larger population.