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유민건 ( Min Gun Yoo ),소병준 ( Byoung Joon So ),김희주 ( Hee Joo Kim ),손길수 ( Gil Soo Son ),박종웅 ( Jong Woong Park ),김일환 ( Il Hwan Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.4
Subungual melanoma is a variant of acral lentiginous melanoma and is thought to carry a poor prognosis due to difficulties in early diagnosis. Classical management of subungual melanoma is based on the radical surgery of distal phalanx amputation. Instead, conservative treatment with non-amputative wide excision of the nail unit followed by reconstruction has been insufficiently reported, especially in Korea. A 71-year-old woman presented with dark brownish longitudinal bands on her right thumbnail. Punch biopsies from the nail matrix and nail bed showed proliferation of atypical melanocytes without dermal involvement. We describe a case of subungual melanoma in situ of the right thumb, and a non-amputative surgical management which aims to provide adequate clearance of the lesion with minimal morbidity and satisfactory preservation of function for the patient. (Korean J Dermatol 2013;51(4):265∼267).
유민건 ( Min Gun Yoo ),박재범 ( Jae Beom Park ),장희원 ( Hee Won Jang ),이상근 ( Sang Geun Lee ),손상욱 ( Sang Wook Son ),김일환 ( Il Hwan Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.12
Background: The relationship between viral hepatitis and lichen planus (LP) remains as a matter of controversy. Geographical variations are suggested to be a major factor influencing such association. Reliable figures from Korean patients are still lacking. Objective: The aim of this study is to determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in Korean patients with lichen planus (LP) and to compare it with patients without LP. Methods: The retrospective study was performed on 45 LP patients and 45 controls with matching age and gender. We examined for serological evidences of hepatic disease, hepatitis B surface antigen (HBsAg), and anti-HCV seropositivity. Statistical analysis was calculated by using an unpaired t-test and Fisher`s exact test. Results: No significant differences between the serum levels of alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were observed between the two groups. The prevalence of HBsAg in LP patients (4.4%) was not significantly higher (p>0.05) than those of the control subjects (2.2%). None of the patients with LP nor the control subjects had Anti-HCV. Conclusion: Korean patients with LP did not have any significant associations with liver diseases or HBV, and HCV infections. Although a large-scale multicenter study is needed to support our results, it is not advisable for Korean patients with LP to be tested for liver functions or HBV, and HCV infections as part of a routine screening test. (Korean J Dermatol 2013;51(12):956∼959)
이지민 ( Ji Min Lee ),신정진 ( Jung Jin Shin ),장희원 ( Hee Won Jang ),유민건 ( Min Gun Yoo ),서수홍 ( Soo Hong Seo ),김일환 ( Il Hwan Kim ) 대한피부과학회 2016 대한피부과학회지 Vol.54 No.1
Cutaneous squamous cell carcinoma (SCC) is the second most common skin malignant neoplasm. Cutaneous SCC shows a broad spectrum, ranging from easily managed superficial tumors to highly infiltrative, metastasizing ones that can cause death. We have experienced two patients with SCC with intracranial extension. One case was an 88-year-old man with a tumor on the forehead treated with Mohs micrographic surgery who presented with local recurrence at the perilesional region of the primary site after 3 years. Wide excision was performed, and histologic findings showed a SCC that extended to the dura mater. The other case was a 69-year-old woman who presented with an erythematous 2×4 cm-sized plaque on the right temple, and a biopsy examination revealed SCC. The patient refused surgery and 7 months later, presented with a 5×10 cm-sized oozing plaque with multiple ulcers. Radiologic evaluation demonstrated intracranial invasion and right retropharyngeal metastatic lymph nodes. She was treated with radiotherapy for 4 months. (Korean J Dermatol 2016;54(1): 56∼61)