http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
활성산소에 의한 심근독성 및 공과의 보호효과에 관한 연구
유교상,손영우,이용석 대한동의생리학회,대한동의병리학회 2002 동의생리병리학회지 Vol.16 No.6
To examine the cardiotoxicity of glucose oxidase(GO) in cultured myocardial cells, cardiotoxicity was measured by MTT assay. Myocardial cells were treated with 1-50 mU/ml GO for 5 hours. The cardioprotective effect of Benincasae Semen(BS) was measured by MTT assay in these cultrures. Cell viability was significantly decreased in dose-and time-dependently after myocardial cells were exposed to 30mU/ml GO for 5 hours. In the cardioprotective effect of BS on the cardiotoxicity induced by GO, BS prevented the cardiotoxicity induced by GO in these cultures. From these results, it suggests that GO had cytotoxic effect in cultured myocardial cells and herb extraxt, BS showed protective effect on GO-induced cardiotoxicity.
관상동맥 조영술을 시행한 환자에서 신동맥 협착의 유병율과 이에 연관된 위험인자 분석
유교상(Kyo Sang Yoo),강재영(Jae Young Kang),장재원(Jae Won Jang),서장원(Jang Won Seo),정영옥(Young Ok Jung),유혜승(He Sung Yoo),박성욱(Seong Wook Park),박승정(Seung Jung Park),박정식(Jung Sik Park) 대한내과학회 1998 대한내과학회지 Vol.54 No.3
N/A Objectives: The distributive pattern of atherosclerotic vascular disease is known to be different among the races. In Caucasian population, renal artery stenosis (RAS) was reported to be a frequent finding in the patients with ischemic heart disease (IHD), ranging from 5% to 29%. We investigated the prevalence of RAS and the risk factors in Korean patients. Methods: Over a 12-month period, 574 patients (M:F, 407:167) with clinical ND underwent cardiac catheterization. Before the procedure, demographic data, medical history, physical findings, and blood chemistries were obtained. During the procedure, selective renal arteriogram was also obtained. The degree of renal artery stenosis was quantitated with automatic edge detection technique, and narrowing of diameter greater than 50% was considered to be significant. Results : RAS was identified in 42 patients (7%), of whom 5 patients (1%) had bilateral disease. Angiographically significant coronary artery disease was present in 473 patients. The prevalence of RAS in patients with single, double and triple vessel disease of coronary artery were 4% (9/235), 13% (20/154), and 12% (10/84), respectively, Among the 101 patients with normal coronary arteries, 3 (3%) had RAS. By univariate analysis, there was significant difference between RAS and non-HAS in age (66±8 yrs vs 59±10 yrs, p<0.0001), duration of hypertension (73±13 yrs vs 3.40.3 yrs, p=0.0002), and the frequency of double or triple ±coronary artery disease (p=0.004). However, no association was found between RAS and serum lipids, lipoprotein(a), creatinine, sex, smoking, diabetes mellitus, or peripheral vascular disease. By multivariate logistic regression analysis, the following parameters were independent risk factors for RAS: age over 65 years (p<0.001), duration of hypertension (p=0.003), and coronary artery disease involving double or triple vessels (p=0.004). Conclusion : The prevalence of RAS in Koreans is somewhat lower than in western population. However, in patients with high degree coronary heart disease, old age over 65 years, or long history of hypertension, the possibility of combined RAS should be considered.
유교상 ( Kyo Sang Yoo ) 대한내과학회 2008 대한내과학회지 Vol.75 No.6
Gallstones are often suspected on history and clinical examination alone but symptoms may be variable ranging from asymptomatic to complications such as biliary pain, cholecystitis, jaundice, cholangitis, or pancreatitis. The clinical presentation of gallstone disease may depend on ongoing complications. Patient with gallstone usually present with characteristic biliary pain which is often situated in the right upper quadrant or epigastrium lasting more than thirty minutes to several hours. Diagnostic investigations aimed to predict the presence and location of stones include history, laboratory tests, and imaging studies. Imaging studies such as transabdominal ultrasonography, computed tomography, magnetic resonance cholangiopancreatography, and endoscopic ultrasonography, frequently confirm the diagnosis and identify the location and etiology of the obstruction. (Korean J Med 75:616-623, 2008)
유교상 ( Sang Yoo Kyo ) 대한내과학회 2014 대한내과학회지 Vol.87 No.3
Pancreatic cystic neoplasms are frequently recognized on routine screening cross-sectional imaging studies, such as computed tomography (CT) and magnetic resonance imaging (MRI), which can be used in their diagnosis and management when characteristic features are present. However, not all such neoplasms can be evaluated completely with CT or MRI and the diagnosis and risk of malignancy are often unclear. Despite recent advances in these diagnostic modalities, the preoperative diagnosis of pancreatic cystic tumors remains difficult. Endoscopic ultrasonography (EUS) has been used increasingly for the diagnosis of pancreatic cystic tumors, as it provide high-resolution images of pancreatic cystic tumors and EUS-guided fine needle aspiration (EUS-FNA) can enable the analysis of cystic fluid for cytology and tumor markers. EUS-FNA provides useful information for the differential diagnosis of mucinous cystic lesions, although it has limited diagnostic accuracy. Other techniques and markers are needed to improve the diagnostic accuracy of mucinous cystic lesions. (Korean J Med 2014;87:251-260)