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      • KCI등재

        양측성 제1대구치 이소맹출 치료의 치험례

        오미희,이수언,최성철,김광철,최영철,박재홍,Oh, Mee Hee,Lee, Soo Eon,Choi, Sung Chul,Kim, Kwang Chul,Choi, Yeong Chul,Park, Jae-Hong 대한소아치과학회 2013 大韓小兒齒科學會誌 Vol.40 No.1

        제1대구치의 이소맹출은 치아가 비정상적 위치로 맹출하는 경우를 말하며 이 경우 제2유구치 원심면의 비정상적 조기흡수를 야기한다. 제1대구치의 이소맹출은 인구의 3~4% 정도에서 나타나며 주로 상악에서 호발한다. 이소맹출한 치아의 66% 정도는 별다른 치료 없이 자발적으로 맹출 경로를 개선하는데 반해 비가역적 이소맹출의 경우에는 능동적 치료가 필요하다. 치료 방법은 크게 두 가지로 나눌 수 있다: 치간이개와 원심경사. 치간이개는 매복 정도가 최소인 경우 시행할 수 있으며, 매복이 심한 경우에는 원심경사가 필요하다. 현재까지의 대부분의 보고들은 편측성 이소맹출의 치료방법에 대해 다루었으며 양측성 이소맹출의 치료에 관한 보고는 많지 않다. 본 증례들은 양측성 제1대구치 이소맹출을 보이는 환아들로 modified bilateral Halterman appliance를 이용하여 양호한 치료결과를 얻었기에 이를 보고하는 바이다. Ectopic eruption of the first permanent molar is an abnormal positioning of this tooth, causing a premature resorption of the distal surface of the second primary molar. It occurs in approximately 3~4% of the population and the maxillary arch is usually affected. While 66% of ectopically erupting permanent molars are corrected spontaneously without treatment (i.e. a reversible type), active treatment is necessary for irreversible ectopic eruption cases. The treatment modalities have been divided into two categories: interproximal wedging and distal tipping. Interproximal wedging is indicated for minimal impaction and when the impaction is severe, distal tipping techniques are required. Although much has been written about treatment modalities on unilateral ectopic eruption of the first permanent molar, few reports mention bilateral ectopic eruption cases. In this report, two cases of bilateral ectopic eruption of the first permanent molars in young patients are presented. We describe the use of a modified bilateral Halterman appliance for correction of these cases and the clinical results were satisfactory.

      • KCI등재후보

        심방중격결손증 환자에서 도플러심초음파와 심도자술을 이용한 폐혈류량과 체혈류량의 비교

        오미희(Mee Hee Oh),전근재(Geon Je Jeon),민병철(Byoung Chul Min),박금수(Keum Soo Park),최경훈(Kyung Hoon Choe) 대한내과학회 1989 대한내과학회지 Vol.37 No.3

        N/A The measurement of systemic flow (Qp) and pulmonary flow (Qs) is clinically important in the management of adult patients with an atrial septal defect. In clinical practice, this is usually assessed by oximetry, radionuclide technique. 1n previous experimental and pediatric studies, the ratio of pulmonary to systemic flow (Qp/Qs) was accurately estimated by Doppler echocardiography in various cardiac shunt lesions. The purpose of this study was to assess the accuracy of pulsed Doppler echocardiography in adult patients with atrial septal defect. In 10 patients and 10 normal persons, blood flow was measured in the right and left ventricular outflow tracts by pulsed Doppler echocardiography and compared with the oximetric measurement. The results were as follows; 1) In 10 patients without heart disease, the correlation (r) between systemic (Qs) and pulmonary (Qp) blood flow was 0.91 (y=0.88 x±0.8) and the Qp/Qs ratio ranged from 0.85 to 1.14 (mean 0.96±0.09). 2) In 10 patients with an atrial septal defect, the mean Qp/Qs ratio measured by oximetry was 1.68J0.46 and by pulsed Doppler echocardiography was 1.56±0.30 (p=NS). In these patients, the correlation between the Qp/ Qs ratio determined by oximetry and pulsed Doppler echocardiography was significant (r=0.89, y=0.58x±0.58). 1n adult patients with artial septal defect and high quality echocardiograms, the magnitude of the pulmonary to systemic flow ratio can be assessed by noninvasive and simple pulsed Doppler echocardiography.

      • SCOPUSKCI등재
      • KCI등재

        한국인 남성 알코올 의존증에서 나타난 도파민 D2 수용체의 대립유전자형 빈도

        이종섭(Jong Sub Lee),오미희(Mee Hee Oh),이창훈(Chang Hoon Lee),송경순(Kyoung Soon Song),배종훈(Jong Hoon Bae),기선완(Sun Wan Ki),이홍식(Hong Shick Lee),유계준(Kae Joon You) 한국중독정신의학회 1997 중독정신의학 Vol.1 No.1

        Dopamine D2 receptor(DRD2) gene is known to have a strong effect on susceptibility of alcohol dependence and to play an important role on appetite such as alcohol seeking behavior. It is known that alcohol induces excitatory effects on dopamine neurons and stimulates brain reward systems by which man craves euphorogenic reward effect of drug(such as alcohol). And it has been suggested that DRD2 has a direct role on alcohol seeking behavior. This study investigated polymorphic patterns of DRD2 gene of Korean male alcohol dependence by restriction fragment length polymorphism(RFLP) and associations of Korean character traits with susceptibility on alcohol. Also, this study examined allelic association of DRD2 gene in various chara cteristics and alcohol-related of alcohol dependence. Subjects of this study consisted of 71 patients with alcohol dependence and 139 healthy male subjects without alcohol dependence for the study of allelic association of DRD2 gene in Korean male alcohol dependence. Allelic association of DRD2 gene between two groups was tested by chi-square test, and those in severity and family history of alcohol dependence, age onset of alcohol drinking, and duration of alcohol drinking history were tested by ANOVA and t-test. The results were as followings; 1) A1A1, A1A2, A2A2 genotype frequency of DRD2 gene in Korean male alcohol dependence were 19.7%, 29.6%, 50.7% and those of control group were 15.8%, 51.8%, 33.1%. There was statistically significant difference between two groups. 2) Ratios of Korean male alcohol dependence with and without A1 allele were 0.49, 0.51 respectively, and those of control groups were 0.67, 0.33 respectively. The difference between two groups were statistically significant. But the difference between two groups on ratio of presence of A2 allele was not statistically insignificant. 3) A1 and A2 allelic frequencies of Korean male alcohol dependence were 0.35 and 0.65 and those of control group were 0.42, 0.58 respectively. So there was no evidence of DRD2 A1 allelic association in Korean alcohol dependence. 4) According to Diagnostic Criteria of National Council on Alcoholism(NCA) on severity alcohol dependence, the genotype of the most severe alcohol dependence was A1A1. on the other hand, the less severe type was A1A2, and the least severe type was A2A2. And A1 and A2 allele frequency of severe alcohol dependence were 0.46 and 0.54 respectively and those of less severe alcohol dependence were 0.18 and 0.72 respectively. Therefore, there was allelic association of DRD2 gene in severity of Korean male alcohol dependence. 5) There were statistically significant differences among subgroups with A1A1, A1A2, A2A2 genotypes on scores of NCA in total patients with alcohol dependence and also significant differences between patients with alcohol dependence with and without A1 allele on scores of NCA. Therefore, there was statistically significant possibility in allelic association of DRD2 gene in NCA scores of patients with alcohol dependence. 6) There were no allelic associations of DRD2 gene in the variable characteristics(age, family history of alcohol dependence, onset age of alcohol drinking, and onset age of alcohol problems). 7) In comparing A1 allelic frequencies of DRD2 gene in this study with those in other studies on various populations, there were no differences statistically among Asians in controls and statistically significant differences, however, in other populations elsewhere. And there were also higher in A1 allelic frequencies in Korean and Japanese with alcohol dependence than the whites. In summarizing above results, there was no allelic association of DRD2 gene in Korean male alcohol dependence, but there was the possibility of A1 allelic association in severity of alcohol dependence. So this study implied that Korean alcohol dependence were influenced by extenal factor like severity of alcohol dependence rather than genetic factor. Therefore

      • 폐결핵의 진단 및 치료반응의 평가에 있어 PCR의 임상적 유용성

        유종길,오미희 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

        Since its development by Saiki et al, polymerase chain reaction(PCR) has been very useful in the diagnosis of Mycobacterium tuberculosis. PCR was employed to detect Mycobacterium tuberculosis in 145 samples from patients with active tuberculosis, other pulmonary diseases and controls, and the results were compared with culture and clinical findings. None of culture negative samples from 20 healthy controls were PCR positive. Of 80 active tuberculosis patients, 65(81.3%) patients were PCR positive and it was significantly higher than the positive results by smear[46(60.0%)], and was similar to the positive results by culture [64(80.0%)]. 40(83.3%) of 48 smear positive and 25(78.1%) of 32 smear negative specimens were positive by PCR. 52(81.3%) of 64 culture positive and 13(81.3%) of 16 culture negative specimens were positive by PCR. In 25 specimens from inactive tuberculosis patients, 1(3.8%) gave PCR positive results, and 5(23.8%) of 21 specimens from patients with other pulmonary diseases (bronchitis, pneumonia etc) were PCR positive. Therefore, this study suggests that PCR could be a very rapid, sensitive and specific method for the early diagnosis of pulmonary tuberculosis, especially in the smear negative sputum. However, to minimize false negative results, getting high quality specimens and decontamination before analysis are very important. Also, the interpretation of PCR results in sputums of pulmonary diseases should be done carefully, and further studies should be performed in PCR positive and culture negative patients.

      • 여성 요실금에서 Kontinence™와 Compact Elite™의 치료효과 비교

        양상국,정상원,오미희,노용수,김홍섭,우응제,박승훈,이수열 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-

        Biofeedback and pelvic floor electrical stimulation are new modalities that have been advocated for the treatment of female urinary incontinence. The aim of this study was to compare prospectively the therapeutic effect of Kontinence™(HMT Co., Korea) with Compact Elite™(ECL Co., France) in female urinary incontinence. All patients were evaluated with a complete history, physical examination, urinalysis, urine culture and urodynamic study. Eighteen patients were treated with Compact Elite™, and thirteen patients with Kontinence™. Enrolled patients had completed 8 office sessions consisting of biofeedback and intravaginal electrical stimulation according to the program of each machines. Overall treatment response was graded by patients on a scale of complete cure to aggravation. At two weeks after last session, overall improvement rate was 78% in Compact Elite™group and 92% in Kontinence™group(p>0.05). Overall patients' acceptability during treatment course was greater than 80% in both machines(p>0.05). There were no unexpected clinical findings during Kontinence™ treatment. After Kontinence™treatment, there were no laboratory changes including electrocardiography, complete blood count, liver function profile, and chest PA. These results showed that the biofeedback and electrical stimulation with Kontinence™was safe and moderately effective for female urinary incontinence comparable to Compact Elite™. However, long-term results of a larger patients are needed to ensure the therapeutic effect of Kontinence™.

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