광대역 4-way 전력분배기 설계

엄태현(Tae Hyun Um),이민규(Min Gyu Lee),김현수(Hyun Soo Kim),한상민(Sang-Min Han) 한국통신학회 2023 한국통신학회 학술대회논문집 Vol.2023 No.2

연속 혈당 측정 데이터를 이용한 딥러닝 기반 저혈당 예측 모델

김현아(Hyun-A Kim),문지은(Ji-Eun Moon),윤영석(Yeong-Seok Yun),이현지(Hyeon-Ji Lee),장혜원(Hye-Won Jang),이혁준(Hyuk-Jun Lee),엄태현(Tae-Hyeon Um),이재선(Jae-Seon Lee),이승천(Seung-Chun Lee) 한국정보과학회 2021 한국정보과학회 학술발표논문집 Vol.2021 No.6

증례 : 혈액종양 ; 영지 섭취 후 일가족에게 발생한 후천재생불량빈혈 4예

정주혁 ( Joo Hyuk Jung ),이현우 ( Hyun Woo Lee ),이유진 ( Yoo Jin Lee ),이혜란 ( Hye Ran Lee ),엄태현 ( Tae Hyun Um ),박지연 ( Ji Yeon Park ),이성윤 ( Seong Yoon Yi ) 대한내과학회 2015 대한내과학회지 Vol.88 No.1

기존에 영지와 관련되어 발생한 후천재생불량빈혈에 대한 보고가 있어 왔다. 저자들은 자가로 영지를 포함한 생약제제로 만든 술을 2-4주 전에 복용한 후 집단적으로 발생한일가족 4예의 재생불량빈혈을 보고한다. 33세 남자 환자와이 환자의 아버지인 65세 남자 환자, 어머니인 63세 여자 환자, 남동생인 31세 남자 환자가 2-4주 전에 영지버섯, 칡, 감초, 대추, 인삼, 더덕을 함께 달여서 만든 추출액을 복용한후에 범혈구감소증을 보였다. 사망자 한 명을 제외하고 나머지 3명은 골수 검사 결과 재생불량빈혈으로 진단 받았다. 환자들은 수혈과 G-CSF 치료, 경험적인 항생제 치료를 받았으며 4-5주 후에 범혈구감소증이 정상으로 회복되었다. 본 4명의 증례 환자들의 임상경과는 영지가 재생불량빈혈의 원인이 될 수 있음을 강력히 시사하고 있다. We report four cases of Ganoderma lucidum-induced aplastic anemia involving members of the same family. A 33-year-old manand three family members were admitted to the hospital due to fever and pancytopenia. The illness arose after ingesting herbal winecontaining G. lucidum 2 weeks earlier. A bone-marrow biopsy showed hypocellularity in three of the four family members (the exceptionwas the one who died). They were treated with supportive management, including transfusions, granulocyte colony stimulatingfactor, and empirical antibiotics for neutropenic fever. The pancytopenia improved 4-5 weeks after the symptoms firstappeared.

담관 감염을 가진 환자에서 담즙배양의 미생물학 및 항균제 감수성에 대한 연구

배원기 ( Won Ki Bae ),문영수 ( Young Soo Moon ),김종훈 ( Jong Hoon Kim ),이석현 ( Seuk Hyun Lee ),김남훈 ( Nam Hoon Kim ),김경아 ( Kyung Ah Kim ),이준성 ( June Sung Lee ),엄태현 ( Tae Hyun Um ),조종래 ( Chong Rae Cho ) 대한소화기학회 2008 대한소화기학회지 Vol.51 No.4

목적: 담관계에서 발생하는 세균 감염은 패혈증을 유발하거나 치명적일 수 있어 즉각적이고 적절한 치료가 필요한 질환이다. 담즙배액과 적절한 항균제의 사용이 담관계 감염의 치료에 있어 매우 중요하다. 이에 이번 연구는 담관계 감염이 발생한 환자에서 시행한 담즙배양을 통해 최근의 담관감염의 원인균 분포 및 항생제 감수성 결과를 알아보고 이를 바탕으로 임상에서 어떤 항생제가 도움이 되는지를 알아보고자 하였다. 대상 및 방법: 2000년 1월부터 2007년 2월까지 인제대학교 일산백병원에서 담관계 감염으로 입원한 환자 중 담관배액술과 함께 담즙배양을 시행한 환자 212명을 대상으로 후향 조사하였다. 담즙의 채취는 환자의 상태와 질병에 따라 내시경 경비 담관배액술, 경피경간 담관배액술이나 경피경간 담낭배액술을 통해 시행하였다. 결과: 담즙배양을 실시한 환자 212명 중 152명에서 배양 양성을 보여 71.7%의 배양률을 보였다. 담관염 환자의 경우 163명 중 119명(73.0%), 담낭염 환자의 경우 49명 중 33명(67.3%)에서 배양 양성을 보였다. 간내 담석을 동반한 경우와 팽대부 주위암의 경우에 모든 환자에서 균배양 양성의 결과를 보였다. 배양된 균주를 보면 E. coli가 54예(25.0%)로 가장 많았으며, 다음으로 Enterococcus spp. 29예(13.4%), Klebsiella spp. 24예(11.1%), Pseudomonas spp. 24예(11.1%) 순이었다. 그람음성균에서는 amoxicillin/clavulanic acid, amikacin, imipenem, piperacillin/tazobactam 등이 높은 감수성을 보였다. 담즙배양을 시행한 환자 212명 중 160명에서 혈액 배양을 동시에 시행하였다. 그 중 50명에서 배양 양성을 보여 혈액 배양의 경우 31.2%의 배양 양성률을 보여 담즙배양의 경우보다 낮았으나 배양된 균주는 담즙배양과 큰 차이를 보이지 않았다. 결론: 담관계 감염을 가진 환자에 있어 초기의 경험적 항균제로는 광범위 penicillin/β-lactamase의 합성제제가 추천된다. 하지만 최근에는 Enterococcus spp나 methicillin-resistant Staphylococcus aureus 등과 같은 그람 양성균에 의한 감염이 늘어나고 있음을 고려하여야 한다. 배양을 통해 원인균이 확인되면 균에 맞는 적절한 항균제로 교체하여야 할 것으로 생각한다. Background/Aims: Bacterial infection of biliary tract may cause severe inflammatory response or sepsis. An immediate bile culture and appropriate antibiotic administration are important to control the biliary tract infection. The objective of the study was to identify organisms in bile and the features of antibiotic susceptibility in patients with biliary tract infection. Methods: We retrospectively reviewed the clinical records of 212 patients whose bile had been cultured for variable biliary tract diseases at Inje University Ilsan Paik Hospital from Jan. 2000 to Feb. 2007. Bile samples were obtained from percutaneous transhepatic biliary drainage (PTBD, n=89), percutaneous transhepatic gallbladder drainage (PTGBD, n=14) or endoscopic naso-biliary drainage (ENBD, n=49). Results: The overall positive rate of bile culture was 71.7% (152 cases). The organisms cultured were Escherichia coli (25.0%), Enterococcus spp. (13.4%), Klebsiella spp. (11.1%), Pseudomonas spp. (11.1%), and coagulase-negative Staphylococcus (9.7%) in decreasing order. Effective antibiotics for Gram-negative organisms were amoxicillin/clavulanic acid, amikacin, imipenem, and piperacillin/tazobactam in order of effectiveness. Of the cultured blood samples from 160 patients, fifty (31.2%) showed positive bacterial growth. The organisms isolated from blood were similar to those found in the bile. Conclusions: A broad spectrum penicillin/β-lactamase inhibitor is a recommendable antimicrobial for empirical treatment for biliary tract infection. However, Gram-positive bacteria such as Enterococcus spp. or methicillin-resistant Staphylococcus aureus are emerging as causative microorganisms. If these organisms are isolated, antimicrobial drugs should be replaced by narrower-spectrum antimicrobials. (Korean J Gastroenterol 2008;51:248-254)

재생불량성 빈혈 환자에서 rhGM-CSF 투여후 말초혈액과 골수소견의 변화

엄태현,윤종현,조한익,김병국 大韓血液學會 1995 大韓血液學會誌 Vol.30 No.3

Plasmodium falciparum 말라리아와 동반된 혈구탐식증후군 1례

엄태현,조종래 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Hemophagocytic syndrome(HPS) associated with malaria, Plasmodium falciparum has not been reported in Korea, although various infectous agents. such as virus, bacteria and fungus have been documented to be associated with HPS. We authors describe a 50-year old male patient with P. falciparum malaria. complicated by HPS. The patient visited emergency department with high fever, chill and mild splenomegaly. He had the history of malaria infection while living in Kenya 2 years ago Peripheral blood smear showed red blood cells infected with the ring forms and sausage-shaped gametocytes of p. falciparum. Bone marrow smear revealed proliferation of mature macrophages with hemophagocytosis of tri-lineage blood cells. The fever and chill disappeared after quinine and mefloquine treatment. Anemia and thrombocytopenia were recovered.

간경변증환자와 원발성간암환자에서의 human alpha-fetoprotein(hAFP)/Type Ⅳ collagen 비

엄태현,이도훈,홍영준,조성석,김진규 대한임상병리학회 1992 대한임상병리학회지 Vol.12 No.4

비예기항체 선별검사의 임상적 유용성

엄태현,신보문 인제대학교 2000 仁濟醫學 Vol.21 No.2

Objectives: Antibody screening test is done for the safer transfusion with minimization of transfusion reaction. We authors evaluated the clinical usefulness of the test by analyzing data of 4789 patients from April 1997 to April 1999 in Seoul Paik Hospital. Methods and Materials: Tube method was performed including saline room tempera Inure, 37℃ albumin, and antiglobulin phase for the antibody screening test using Sur giscreen (Ortho-Clinical Diagnostics, USA). The frequency of unexpected antibodies and its specificity are determined. The amount of blood transfusion and hemolytic transfuion reaction are analyzed by patient chart review. Results: Thirty six patients(0.75%) had the unexpected antibody(ies), with the frequency of anti-Lewis 50%, anti-Rhesus 21.4%, anti-Pl 21.4%, and anti-Hi 7%. RBC blood products were transfused to 9 patients after crossmatching including antiglobulin phase, without any hemolytic transfusion reaction. Conclusions: We concluded that antibody screening test should be done as a pretransfuion test for the safe and rapid RBC transfusion in non-emergency cases.

자동 화학 분석기 ADVIA^(�) 1650의 평가

엄태현,조종래 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Objective : ADVIA?? 1650(Bayer Inc., NY, USA) is an automated chemistry analyzer introduced into Korea in 1999. We evaluated the performance of ADVIA 1650 for precision, linearity, recovery, and compared it with CX7 autoanalyzer(Bookman Instruments, Inc., CA. USA). Methods and Materials : We used pool serum and commercial qualify control materials, such as Control 1 and Control 2(Bayer Inc., NY, USA). A total of 22 test items, such as glucose, blood urea nitrogen(BUN), creatinine, uric acid, total protein, albumin, aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phsphatase(ALP), total bilirubin, choesterol, triglyceride(TG), phosphorus(P), magnesium(Mg), creatine kinase(CK), lactate dehydrogenase(LD). ?-glutamyl transferase(GGT), amylase, sodium(Na), potassium(K), and chloride(Cl) were evaluated. Results : Within-run coefficients of variations(CVs) of all test items except total bilirubin were less than 5%. Between-day CVs were less than 5% except creatinine, AST, ALT, total bilirubin. All test items showed good linearity with CVs higher than 0.99. Recovery rates were in the range of 90% to 106%. The correlations with CX7 were good with CVs higher than 0.97 in most of the test items, except creatinine, total protein and sodium, which showed CVs lower than 0.90. Conclusion : We think that ADVIA 1650 is a useful automatic chemistry anaylzer for high-volume laboratories.

한국인에서 ABO 혈액형과 균혈증의 관련성

엄태현,조종래 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Objectives: There have been debates on the relationship between ABO blood groups and infectious diseases. It is known that blood type A has the tendency to have staphylococcus aureus bacteremia. We investigated this relationship in Koreans. Methods and Materials: We analysed the ABO blood groups in the bacteremia patients in Ilsan Paik hospital, from January 2000 to March 2001. The number of patients with S. aureus bacteremia is 30, coagulase negative Staphylococcus(CNS) 40, Escherichia coli 21, and blood culture negatives(BN) 104. We used the distribution of ABO blood groups of 1,018 patients as the control, for whom ABO blood typings were done in blood bank during December 2000. Results: The frequencies of blood group A, B, O and AB in blood bank controls were 32%, 28%, 28%, and 13%, respectively. For S. aureus bacteremia, they were 20%, 43%, 20%, and 17%; for CNS, 45%, 35%, 15%, and 5%; for E. coli, 24%, 24%, 43%, and 10%, respectively. For BN, they were 35%, 27%, 23%, and 15%, respectively. There were no statistically significant differences in ABO blood groups between control and each bacteremia including BN. But there was the tendency that CNS group had higher frequency of blood type A and lower frequency of blood type O. Conclusions: We concluded that there is no significant relationship between ABO blood groups and bacteremia, but can not deny its presence because of the room for further studios.