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        요오드화 조영제에 의한 고정약진 1예

        심지수 ( Jisu Shim ),정수지 ( Soojie Chung ),김건우 ( Gun Woo Kim ),손경희 ( Kyoung Hee Sohn ),김주영 ( Ju Young Kim ),강혜련 ( Hye Ryun Kang ) 대한천식알레르기학회(구 대한알레르기학회) 2015 Allergy Asthma & Respiratory Disease Vol.3 No.5

        Iodinated contrast media (ICM) can cause not only immediate onset hypersensitivity but also delayed onset hypersensitivity. While the most common form of delayed onset hypersensitivity reaction to ICM is exanthematous eruption, fixed drug eruption (FDE) can occur rarely related to ICM. A 70-year-old male with liver cirrhosis and hepatocellular carcinoma repeatedly experienced erythematous patches on his right forearm and hand 6 hours after exposure to iopromide for computed tomography scan. ICM induced FDE was diagnosed clinically. Intradermal test with 6 kinds of ICM (iobitridol, iohexol, iomeprol, iopamidol, iopromide, and iodixanol) was performed and showed the weakest positive reaction to iohexol compared to the others in 48 hours. After changing iopromide to iohexol based on these results, FDE did not recur. We report here a case of iopromide induced FDE which was successfully prevented by changing ICM to iohexol based on intradermal test results. (Allergy Asthma Respir Dis 2015;3:375-379)

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        한국인 음식물 의존성 운동유발 아나필락시스의 임상적 특성 분석

        정수지 ( Soo Jie Chung ),심지수 ( Jisu Shim ),김형준 ( Hyung-jun Kim ),손경희 ( Kyoung-hee Sohn ),강성윤 ( Sung-yoon Kang ),강민규 ( Min-gyu Kang ),박한기 ( Han-ki Park ),강혜련 ( Hye-ryun Kang ) 대한천식알레르기학회(구 대한알레르기학회) 2016 Allergy Asthma & Respiratory Disease Vol.4 No.6

        Purpose: Food-dependent exercise-induced anaphylaxis (FDEIA) is a rare subtype of food allergy in which both sensitization to food allergen and exercise as a trigger contribute to its development. However, its pathogenesis is still under investigation. This study compared clinical features, the causative foods, and the degree of sensitization to food between FDEIA and food anaphylaxis to characterize FDEIA more clearly. Methods: We retrospectively reviewed the medical records of patients who were diagnosed with FDEIA (n=89) or food anaphylaxis (n=115) between 2003 and 2015 at Seoul National University Hospital. Results: Subjects with FDEIA more frequently had urticaria than those with food anaphylaxis (88.8% vs. 76.5%, P=0.024). Whereas patients with FDEIA had less laryngeal edema than those with food anaphylaxis (12.4% vs. 30.4%, P=0.02). Wheat (67.4%) was the most common causative food allergen in FDEIA, whereas seafood (40.9%) was the most common culprit food allergen in food anaphylaxis. Also, subjects with FDEIA showed a lower atopic index score than those with food anaphylaxis (0.55±1.07 vs. 1.21±1.82, P=0.006). Conclusion: There were significant differences in clinical manifestation, causative food allergens and the degree of sensitization to food between FDEIA and food anaphylaxis. (Allergy Asthma Respir Dis 2016:4:436-441)

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        담화표지 ‘아’, ‘어’, ‘음’의 성별과 연령별 사용 양상

        송영숙(Youngsook Song),심지수(Jisu Shim),오재혁(Jeahyuk Oh) 한국음성학회 2020 말소리와 음성과학 Vol.12 No.4

        이 연구는 담화 표지 ‘아, 어, 음’의 출현 빈도와 발화 시간, 발화 위치 등을 계량적으로 관찰하여 성별과 연령별 차이를 보이고자 하였다. 이를 위해 대용량 음성 코퍼스인 서울코퍼스를 이용하였고, Praat(ver.6.1.31)으로 음길이와 실제 발화를 확인하고, Emeditor(ver.17.6.1)로 코퍼스를 분석하고, R(ver.3.4.4)로 통계 분석하여 결과를 제시하였다. 성별에 따라 보면 여성의 경우 남성보다 단독 발화에서 ‘음’이 고빈도로 사용되었고, 발화 종결 위치에서의 평균 음길이 또한 길었다. 연령에 따라 보면 발화 시작 위치에서 10대에서는 ‘아’가, 40대는 ‘어’가 고빈도로 출현하는 것이 특징적이었다. This paper quantitatively calculated the speech frequency of the discourse markers ‘a’, ‘eo’, and ‘eum’ and the speech duration of these discourse markers using the Seoul Corpus, a spontaneous speech corpus. The sound durations were confirmed with Praat, the Seoul Corpus was analyzed with Emeditor, and the results were presented by statistical analysis with R. Based on the corpus analysis, the study investigated whether a particular factor is preferred by speakers of particular categories. The most prominent feature of the corpus is that the sound durations of female speakers were longer than those of men when using the ’eum’ discourse marker in a final position. In age-related variables, teenagers uttered ‘a’ more than ‘eo’ in an initial position when compared to people in their 40s. This study is significant because it has quantitatively analyzed the discourse markers ‘a’, ‘eo’, and ‘eum’ by gender and age. In order to continue the discussion, more precise research should be conducted considering the context. In addition, similarities can be found in “e” and “ma” in Japanese(Watanabe & Ishi, 2000) and ‘uh’, ‘um’ in English(Gries, 2013). afterwards, a study to identify commonalities and differences can be predicted by using the cross-linguistic analysis of the discourse.

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