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심재만(Jae-Man Sim),이형욱(Hyeong-Wook Lee),신주용(Joo-Yong Shin),김기원(Ki-Won Kim),한영오(Young-Oh Han) 한국전자통신학회 2019 한국전자통신학회 논문지 Vol.14 No.6
본 논문에서는 시각장애인들이 보행 시 장애물이나 위험요소로부터 보다 안전하게 보행 할 수 있도록 보조 장치를 구현하였다. 초음파 센서를 통해 전방에 있는 장애물을 감지하여 거리별, 각도별로 부저의 소리의 간격과 진동의 세기를 다르게 울리도록 했으며 그에 따라 보행자가 상황을 인지할 수 있게 설계하였다. 조도 센서의 CdS 저항값을 이용해 설정해놓은 빛의 밝기보다 주변이 어두워 졌을 시 LED가 자동 점등 되어 주변 보행 자들이 시각장애인을 쉽게 인식할 수 있게 하였으며, 또한 자이로 센서의 기울기를 이용해 보행자가 보조 장치를 놓쳤을 시 부저를 통하여 보조 장치의 위치를 인식할 수 있게 하였다. 그리고 GPS와 블루투스를 이용하여 시각장애인의 위치 및 상황을 보호자에게 전송하여 안전보행을 확인할 수 있게 구현하였다. In this paper, an auxiliary device was implemented to help blind people more safely from obstacles or risk factors while walking. The ultrasonic sensors detect obstacles in the front, so that the noise gap and the vibration intensity of the buzzer can be heard differently by distance and angle, and so the situation can be perceived by pedestrians. When the ambient light becomes darker than the light intensity set using the CdS resistance value of the light sensor, the LED automatically turns on, makes it easier for pedestrians to recognize the position of the auxiliary device through buzzer if the pedestrian misses the aid using the gyro sensor s slope. Moreover, the location and situation of the blind were transmitted to the caregiver to check safety and behavior using GPS and Bluetooth.
TMA로 유도된 접촉성 과민 반응 마우스 질환모델에서 해양성 광천수 도포시의 치료효과
김재진 ( Jae Jin Kim ),김완재 ( Wan Jae Kim ),심재만 ( Jae Man Sim ),최선강 ( Seon Kang Choi ),권순성 ( Soon Sung Kwon ),김정득 ( Jung Duk Kim ),이광호 ( Kwang Ho Lee ) 한국식품영양학회 2010 韓國食品營養學會誌 Vol.23 No.4
Effect of brine mineral water(BMW) on contact hypersensitivity reaction(CHR) was estimated using trimellitic anhydride (TMA) induced CHR in the mouse. BMW exhibited potent inhibitory activity on TMA induced CHR. BMW treatment suppressed the ear swelling, and attenuated hyper-activated lymph nodes stimulated by TMA challenge, thereby reduced their weight. The immunological index was analyzed after BMW administration in CHR. The level of serum IGE was significantly down regulated after BMW treatment. Furthermore, BMW showed inhibitory property of cytokine production. BMW treatment suppressed not only Th2 type cytokine, IL-4 but also pro-inflammatory cytokines such as TNF-α and IL-6. From the histological analysis, the inflammatory context appeared by atopic dermatitis lesion after challenging with TMA are diminished by BMW treatment. Our results suggest that BMW may attenuate the development of CHR, and can be available for functional ingredient.
해양성 광천수의 암세포 성장, 전이 및 신생 혈관 생성 억제 효과
김완재 ( Wan Jae Kim ),리화 ( Hua Li ),윤택준 ( Taek Joon Yoon ),심재만 ( Jae Man Sim ),최선강 ( Seon Kang Choi ),이광호 ( Kwang Ho Lee ) 한국식품영양학회 2009 韓國食品營養學會誌 Vol.22 No.4
Brine mineral water(BMW) has recently gained attention as a new water resource due to its biological activities. In this study, BMW from the Geumjin area(Gangneung-city, Korea) was evaluated for its growth inhibition, anti-metastasis and anti-angiogenesis activity against cancer cells. The in vitro cytotoxicity was measured by CCK assay, and the anti-metastasis activity was estimated by lung metastasis in vivo. The in vitro incubation of mouse splenic cells with BMW that had been diluted more than 4-fold showed no effect on the cell growth when compared to a control group. Additionally, BMW inhibited the growth of the EL-4, L5178Y-R and colon26-M3.1 cancer cell lines in a dose-dependent manner. In vivo evaluation of the anti-metastasis activity of BMW in BALB/c mice inoculated with the colon26-M3.1 cell line revealed dose-dependent inhibition in response to treatment with samples that were diluted by up to 9 times. Finally, treatment with BMW effectively suppressed the growth of vascular endothelial growth factor(VEGF) added human umbilical vein endothelial cells. Overall, these results suggest that BMW has anti-cancer activity.
가공조건과 천연항균제의 처리가 황태양념구이의 품질에 미치는 영향
조순영 ( Jo Sun Yeong ),심재만 ( Sim Jae Man ),최용석 ( Choe Yong Seog ),김옥선 ( Kim Og Seon ) 한국수산과학회 2003 한국수산과학회지 Vol.36 No.5
N/A This research investigated the effects of processing conditions and natural antimicrobial materials on quality of freeze-dried, seasoned and roasted Alaska pollack (Theragra chalcogramma). The optimum dipping time and moisture contents of freeze-dried Alaska pollack were 1 sec in 1% salt solution, 48.6% respectively. The freeze-dried, seasoned and roasted Alaska pollack product showed high sensory value. As sterilization time increased over 30 mins in water bath at 100℃, the browning degree of the freeze-dried, seasoned and roasted Alaska pollack product increased. Among various antibrowning agents, 3% corn starch was better in preventing browning than sporix treatment. The freeze-dried, seasoned and roasted Alaska pollack product added with lactate Ca and catechin had the antimicrobial, and the VBN contents of the product showed low level.