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신영주,문준웅,위원량,Young Joo Shin,Joon Woong Moon,Won Ryang Wee 대한안과학회 2006 대한안과학회지 Vol.47 No.1
Purpose: To investigate the relationship between corneal neovascularization (CNV), corneal hypesthesia and dry eye syndrome. Methods: From July 2003 to November 2004, patients who had history of weraing soft contact lenses were selected and administered the Schirmer test; those with conjunctival inflammation and corneal complications were tested using an esthesiometer, and were given a dry eye questionnaire. Results: A longer period of soft contact lens wear was related to CNV and corneal hypesthesia (p<0.01), and theses two complications showed a significan relationship with symptoms of dry eye syndrome (p<0.01). Conclusions: Corneal neovascularization and corneal hypesthesia should be considered in cases of long term wear of soft contact lenses. The eyes with CNV and corneal hypesthesia had more severe symptoms of dry eye syndrome.
신영주,김남희,김대환,Young Joo Shin,Nam Hee Kim,Dae Hwan Kim 대한안과학회 2007 대한안과학회지 Vol.48 No.5
Purpose: To compare the corneal measurements of orbscan and pentacam in normal subjects. Methods: From April 10 th 2006 to May 10 th 2006, subjects were tested by automated refractokeratometry (Canon RK-1, Japan), Pentacam (OCULUS, Germany), and Orbscan (Orbtek Inc, USA). Measurements included central, superior, nasal, inferior and temporal corneal thickness, radius of anterior elevation and posterior elevation, keratometric value and axis of the 4 mm zone, and anterior chamber depth. Results: A total of 96 eyes from 48 patients were included, with 13 men and 35 women. Average age was 25.4 years old. In comparing the Orbscan and Pentacam, central, superior and temporal corneal thicknesses of the Pentacam were significantly thicker than those of the Orbscan (paired t-test, p=.000, p=.000, p=.003). The mean K value of the 4mm zone of the Orbscan was steeper than that of the Pentacam (paired t-test, p=.000). The anterior chamber depth of the Pentacam was deeper than that of the Orbscan (paired t-test, p=.000), but all of the Pentacam measurements were strongly correlated to those of the Orbscan. Conclusions: The measurements of the Pentacam and the Orbscan were significantly different, but they were strongly correlated. Both machines can be useful in clinical applications with partial compensation.
신영주,김상진,위원량,장윤석,Young-Joo Shin,Sang-Jin Kim,Won-Ryang Wee,Yun-Suk Chang 대한안과학회 2005 대한안과학회지 Vol.46 No.8
Purpose: To report a case of the keratoconjunctivitis sicca (KCS) associated idiopathic hypereosinophilic syndrome (IHES). Methods: We present a report and review of a 53-year-old man who suffered from IHES and KCS. The ocular examination showed conjunctival papillary hypertrophy, interpalpebral corneal and conjunctival punctate staining with fluorescein dye, and peripheral corneal neovascularization. His Schirmer I test results were nearly zero mm of wetting in both eyes. Impression cytology showed squamous metaplasia. Results: He had treated with low dose systemic steroid since October 2003. Because he showed a side effect of steroid induced myopathy, we could not increase the dosage. We added topical steroid (Pred Forte?), conservative free artificial tear and topical antibiotics, after which his ocular condition improved. Neovascularization was regressed, punctate staining decreased, and his visual acuity increased to 20/25 2 months later. Conclusions: This case demonstrates that the KCS can be associated with IHES and be treated with systemic and topical steroid.
신영주,전혜원,최병민,유기환,홍영숙,이주원,김순겸,Shin Young-Ju,Cheon Hae-Won,Choi Byung-Min,Yoo Kee-Hwan,Hong Young-Sook,Lee Joo-Won,Kim Soon-Kyum 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.1
목적 : 혈청전해질 분석기의 종류에 따라 anion gap(이하 AG)의 새로운 참고치가 외국에서 발표되고 있으며, 현재 사용되고 있는 참고치보다 낮게 측정된 연구가 보고되고 있다. 따라서 저자들은 현재 사용되고 있는 분석기에 따른 새로운 AG의 참고치가 필요하였기에 연구를 시행하게 되었다. 방법 : 1997년 3월부터 1997년 7월까지 본원 소아과에 입원한 환아와 이비인후과 수술을 받기 위해 수술전 검사를 시행한 환자중 정상 혈청 알부민과 크레아티닌 수치를 가진 환자 395명을 대상으로 하였다. Na, Cl은 Hitachi 747 analyzer를 이용하여 측정하였고, $TCO_2$는 CX-3 analyzer를 이용하여 측정하였다. 결과 : AG은 한달이내, $11.2{\pm}3.2$ mEq/L; 한달${\sim}1$세미만, $11.8{\pm}2.7$ mEq/L; 1세${\sim}5$세미만, $12{\pm}2.7$ mEq/L; 5세${\sim}10$세미만, $11.7{\pm}3.2$ mEq/L; 10세${\sim}20$세미만, $9.6{\pm}2.7$ mEq/L ; 20세${\sim}60$세, $9.0{\pm}2.7$ mEq/L이며, 10세 이상에서 AG이 현재 사용되고 있는 참고치보다 낮게 측정되었으나 10세미만 그룹에서는 차이점이 업었다. 결론 : 각 병원마다 사용중인 분석기에 따라서 나이별로 AG의 새로운 정상 범위가 결정되어야 할 것으로 생각된다. Purpose: The old reference range of serum anion gap(AG) may be excessive compared with value measured by new electrolyte analyzers. Therefore, we studied to establish a new reference range of AG using an autoanalyzer. Methods: With the use of analyzer(Hitachi 747 by enzymatic methods), serum Na and Cl were measured, and with the use of analyzer(CX-3 by differental rage pH), serum $TCO_2$ was measured. We measured AG(=Na-($Cl+HCO_3$)) in 395 stable patients with normal serum albumin and creatinine levels of the pediatric in-patients and out-patients for preoperative examination from march 1997 to July 1997. Results: The normal serum$ AG(mean{\pm}SD)$ were neonate, $11.2{\pm}3.2$ mEq/L; infancy, $11.8{\pm}2.7$ mEq/L; early childhood, $12{\pm}2.7$ mEq/L; late childhood, $11.7{\pm}3.2$ mEq/L; adolescence, $9.6{\pm}2.7$ mEq/L; adult, $9.0{\pm}2.7$ mEq/L. Normal serum AG in more than 10 years of age was significantly lower than the previous normal value and also the difference of AG between more than 10 years and less than 10 years was statistically significant(P<0.05). Conclusions: We suggest to measure serum AG according to each type of analyzers.
신영주,위원량,이진학,양승지,노용만,Young Joo Shin,Won Ryang Wee,Jin Hak Lee,Seung Ji Yang,Yong Man Ro 대한안과학회 2006 대한안과학회지 Vol.47 No.10
Purpose: to study the utility of a program which diagnoses and compensates for color defects on computer monitors according to the severity and type of color vision deficiency (CVD). Methods: Twenty-eight patients with congenital CVD completed Seohan computerized hue test, color compensated Seohan computerized hue test and questionnaire for preference of color compensated images. The relation between results of the Seohan computerized hue test and the degrees of color compensation was investigated. HRR test and Nagel anomaloscope were used for determining the severity and type of CVD. Results: In applying the color compensation program, the total error score (TES) of the Seohan computerized hue test was significantly reduced. In cases of milder color vision defect, the TES of the color compensated Seohan computerized hue test was reduced at lower color compensations, while it was reduced at higher color compensations in cases of more severe color vision defect. In the color compensation of images, patients with milder color vision defects preferred images with lower color compensation and patients with more severe color vision defect preferred images with higher color compensation. Conclusions: The color compensation program for CVD effectively reduced the TES of Seohan computerized hue tests and improved the recognition of colors. This suggests that the program can be helpful to actual life in patients with CVD.