"삼국사기(三國史記)"에 기록된 의약내용(醫藥內容) 분석

신순식,최환수,Shin, Soon-Shik,Choi, Hwan-Soo 제3의학회 1997 제3의학 Vol.2 No.1

We tried to observe the features of ancient medical practice by analysing the records related to medicine in the book, ${\ulcorner}$the Historical Records of the Three Kingdom${\lrcorner}$ of which content includes the features of medicine in mythology, plague, delivery of twins, drugs, medical system, shamanism, constitutional medicine, psychiatry, forensic medicine, deformity, a spa, medical phrase, health and welfare work, religion, death. physiological anatomy, Taoist medicine, acupuncture, the occult af of transformation and etc. Our initial concern was about where to draw line as of medical field and we defined medicine in more broad meaning. The book ${\ulcorner}$the Historical Records of the Three Kingdoms${\lrcorner}$ describes the world of mythology by way of medicine which is not clearly a conventional one. There appears records of birth of multiple offsprings 7 times in which cases are of triplets or more. Delivering multiple offsprings were rare phenomenon though such fertility was highly admired. This shows one aspect of ancient country having more population meant more power of the nation. Of those medical records conveyed in that book includes stories of childbirth such as giving birth to a son after praying, giving birth to Kim Yoo-shin after 20 months after mother's dream of conception, and a song longing for getting a laudable child. Plagues were prevalent throughout winter to spring season and one can observe various symptoms of plagues in the record. Of these epidemic diseases, cold type might have been more common than the heat one. Appearance of epidemic diseases frequently coincided with that of natural disasters that this suggests a linkage between plague and underlying doctrine on five elements' motion and six kinds of natural factors. There exists only a few names of diseases such as epidemic disease, wind disease, and syndrome characterized by dyspnea. Otherwise there appeared only afflictions that were not specified therefore it remains cluless to keep track of certain diseases of prevalence. Since this ${\ulcorner}$Historical Records of the Three Kingdoms'${\lrcorner}$ wasn't any sort of medical book, words and terms used were not technical kind and most were the ones used generally among lay people. Therefore any mechanisms of the diseases were hardly mentioned. Some of medicinal substances such as Calculus Bovis, Radix Ginseng, Gaboderma Luciderm, magnetitum were also in use in those days. 53 kinds of dietary supplies appears in the records and some of these might have been used as medicinal purpose. Records concerning dicipline of one's body includes activities such as hunting, archery, horseback riding etc. In Shilla dynasty there were positions such as professor of medicine, Naekongbong(內供奉), Kongbong's doctor(供奉醫師), Kongbong's diviner(供奉卜師). As an educational facility, medical school was built at the first year of King Hyoso's reign and it's curricula included various subjects as ${\ulcorner}$Shin Nong's Herbal classic${\lrcorner}$, ${\ulcorner}$Kabeul classic of acupuncture and moxbustion${\lrcorner}$, ${\ulcorner}$The Plain Questions of the Yellow Emperor's Classic of Internal Medicine${\lrcorner}$, ${\ulcorner}$Classic of Acupuncturer${\lrcorner}$, ${\ulcorner}$The Pulse Classic${\lrcorner}$, ${\ulcorner}$Classic of Channels and Acupuncture Points${\lrcorner}$ and ${\ulcorner}$Difficult Classic${\lrcorner}$. There were 2 medical professors who were in charge of education. To establish pharmacopoeia, 2 Shaji(舍知), 6 Sha(史), 2 Jongshaji(從舍知) were appointed. In Baekje dynasty, Department of Herb was maintained. Doing praying for the sake of health, doing phrenology also can be extended to medical arena. Those who survived over 100 years of age

고지방식이 마우스 비만모델에서 감비경신환(減肥輕身丸)(2)에 의한 혈중 중성지방 농도와 내장지방의 변화

신순식,이희영,이혜림,윤미정,이용태,Shin, Soon-Shik,Lee, Hee-Young,Lee, Hye-Rim,Yoon, Mi-Chung,Lee, Yong-Tae 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.2

Objectives : We investigated the effects of gambigyeongsinhwan2(GGH(2)) on body weight and examined whether blood triglyceride levels and visceral fat are inhibited by it in high fat diet-fed obese male mice. Methods : 8 weeks old, high fat diet-fed obese male mice were divided into 5 groups: C57BL/6N normal, control, GGH(2)-1, GGH(2)-2 and GGH(2)-3. After mice were treated with GGH(2) for 8 weeks, we measured body weight gain, food intake, feeding efficiency ratio, fat weight, plasma leptin and lipid levels. We also did histological analysis for liver and fat on the mice. Results : 1. Compared with controls, GGH(2)-treated mice had lower body weight gain and adipose tissue weight, the magnitudes of which were prominent in GGH(2)-3. 2. Compared with controls, GGH(2)-treated mice had lower feeding efficiency ratio, the magnitude of which was prominent in GGH(2)-3. 3. Compared with controls, GGH(2)-treated mice had lower blood plasma triglyceride level. 4. Blood plasma AST and ALT concentrations were not changed by GGH(2), indicating GGH(2) do not show any toxic effects. 5. Consistent with their effects on body weight gain, the size of adipocytes were significantly decreased by GGH(2), whereas the adipocyte number per unit area was significantly increased, suggesting that GGH(2) decreased the number of large adipocytes. Hepatic lipid accumulation was decreased by GGH(2). Conclusions : These results demonstrate that GGH(2) effectively reduces body weight gain, feeding efficiency ratio, blood plasma triglyceride level and improves abdominal fat.

"임증지남의안(臨證指南醫案)"권일(卷一) "현운(眩暈)"에 대한 고찰

신순식,Shin, Soon-Shik 제3의학회 1996 제3의학 Vol.1 No.2

${\ulcorner}Volume\;1{\lrcorner}$ of ${\ulcorner}$Medical Records as a Guide to Clinical Works${\lrcorner}$, written by Ye Tian Shi, showed some clinical cases of dizziness. In this study, his diagnosis and treatment was studied with 16 clinical cases of dizziness with pathogenic factor, pathogenesis and symptoms of dizziness. Ye Tian Shi thought that phlegm, fire, wind and insufficiency were the causes of dizziness and phlegm-fire, phlegm-fire-wind, wind-phlegm and insufficiencyfire-wind were the causes of dizziness, clinically. Dizziness is caused when the body is in condition of excess in the upper and deciency in the lower. The acompanying clinical symptoms of dizziness are endogenous wind, fire of deficiency type, phlegm wind and phelegm fire. For the treatment of dizziness, Ye Tian Shi used the combination of medicines with some modifications by the cases for phlegm, fire, wind and insufficiency. He also encouraged the mental therapy for the treatment of dizziness. He emphasized the early treatment of dizziness to prevent hemiplegia after apoplexy. It can be postulated from Volume 1 of ${\ulcorner}$Medical Records as a Guide to Clinical Works${\lrcorner}$, diagnosis and treatment of symptoms and illness of Ye Tian Shi was strictly based on actual clinical cases.

"동의림상방제학(東醫臨床方劑學)"의 편집체제와 특징

신순식,Shin, Soon Shik 대한한의학방제학회 2013 大韓韓醫學方劑學會誌 Vol.21 No.1

Objectives : Examined the editing system and the characteristics of "Clinical Formula Science of Korean Medicine" to establish a basis for compilation system of the common formula science textbook for colleges of Korean medicine nationwide. Methods : Comprehended the "Clinical Formula Science of Korean Medicine" published by professor Hyeongok(1911-1987) in 1985 and analyzed its configuration system. Results : "Clinical Formula Science of Korean Medicine" has made it possible to understand the formula systematically by establishing and classifying 24 kinds of treatment method [the three treatment methods of cold-dampness, dryness-heat and interior deficiency and its subdivision, 19 kinds of treatment method (stomach, phlegm, eum, yang, spirit, essence, ki, blood, blood stasis, exterior, interior, half-exterior half-interior, water, wind, cold, heat, dampness) combined with reducing and vomiting] and main formula. These can be considered as professor Hyeongok's own method of classification, which is distinctive from the existing formula science system. Also, it suggests that a Korean medicine doctor should not use a biased formula science that is limited to some schools but apply the formula widely and synthetically because it is believed to pursue perfection in cure if the main formulas related to a physical disorder, pregnancy and childbirth, invigorating and purging five viscera, and Four-Constitution Medicine are added. Conclusions : "Clinical Formula Science of Korean Medicine" is seen as a formula science book which is to be consulted when compiling a common formula science textbook for colleges of Korean medicine by forming a Korean formula science system that is distinctive from that of China.

방제학 공통교재에 수재할 곽향정기산(藿香正氣散)의 배오(配伍) 분석

신순식,Shin, Soon Shik 대한한의학방제학회 2013 大韓韓醫學方劑學會誌 Vol.21 No.1

Objectives : Proposed a formula analysis standard about the individual formula which is to be put in the specific discussions in order to increase the effect of formula education at the college of Korean medicine. Methods : Examined the ingredient combination analysis written in Agastache Powder to Rectify the Ki which was put in the 27kinds of formula science book published in both Korea and China. Results : Must analyze the formula according to the existing formula. The combination of the ingredients should be analyzed into herb pairs such as seven different combinations. The effect and disease for which medicine is efficacious, should be analyzed and tabulated by Agastache Powder to Rectify the Ki. The formula should be anlayzed and schematized by the sytem of Chief, Deputy, Assistant and Envoy. The basic formula should be analyzed and schematized by the combination of formula, adding and removing the ingredients. Analyzing Agastache Powder to Rectify the Ki into the system of Chief, Deputy, Assistant and Envoy shows the following: chief herb is Agastaches Herba; deputy herb is Perillae Folium and Angelicae dahuricae Radix; assistant herb is Pinelliae Rhizoma preparatum, Magnoliae officinalis Cortex, Citri reticulatae Pericarpium, Arecae Pericarpium, Platycodi Radix, Atractylodis macrocephalae Rhizoma, Poria, and envoy herb is Glycyrrhizae Radix preparata, Zingiberis Rhizoma recens, Jujubae Fructus. Conclusions : In conclusion, it is believed that the formula education at colleges of Korean medicine would be effectively achieved if it is processed according to the standardized formula analysis and its rule about individual formula that is to be decided.

현곡(玄谷) 오장(五臟) 보방(補方)의 조성 약물과 그 기미배오(氣味配伍) 분석

신순식,Shin, Soon-Shik 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.1

Objectives : The objective of this study lies in theoretical establishment of formulas for invigorating five viscera for curing the asthenic syndrome of five viscera through analyzing the component medicines and combination principles of Hyeongok's formulas for invigorating five viscera, and furthermore, maximizing the clinical use of them. Methods : This study analyzed the component medicines and combination principles of Hyeongok's formulas for invigorating five viscera based on the theory for properties and tastes of herbal medicines from the "Yellow Emperor's Canon of Internal Medicine", the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine, and the five elements doctrine. Hyeongok's formulas for invigorating five viscera are Bogantang, Boseemtang, Bobeetang, Bopyeotang, and Boshintang. Results : There are three methods for curing the asthenic syndrome of five viscera according to the five elements doctrine: in case of Bogantang invigorating the liver, invigorating the kidney and purging the lung; Boseemtang, invigorating the heart, invigorating the liver and purging the kidney; Bobeetang, invigorating the spleen, invigorating the heart and purging the liver; Bopyeotang, invigorating the lung, invigorating the spleen and purging the heart; Boshintang, invigorating the kidney, invigorating the lung and purging the spleen. Conclusions : First, to cure the asthenic syndrome of five viscera, the methods of invigorating five viscera, and purging five viscera should be used according to the five elements doctrine. Secondly, herbal medicines appropriate for those treatment methods should be chosen according to the theory for properties and tastes of herbal medicine and thirdly, the combination of those herbal medicines should be carried out according to the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine. As a good example, Hyeongok's formulas for invigorating five viscera are combined according to the above theories. In conclusion, this formula was created by applying to the theory for properties and tastes of herbal medicines.

"임증지남의안(臨證指南醫案)"에 관한 연구

신순식,홍원식,Shin, Soon-Shik,Hong, Won-Sik 한국한의학연구원 1995 한국 한의학연구소 논문집 Vol.1 No.1

A proper understanding of 'diagnosis and treatment based on overall analysis of symptoms and signs' can result in efficient clinical effect. Studies on the ${\lceil}$Medical Recoreds as a Guide to Diagnosis${\rfloor}$ can be expected to achieve a part of this purpose. In this study, the period, author, xylographica, contents and influence of next generation of ${\lceil}$Medical Records as a Guide to Diagnosis${\rfloor}$were investigated. Tian shi and his 12 followers completed thsis Medical recoreds with clinical experiences and data obtained throughout their lives. These books were first published in 1764. Since then these books have been published twenty times based on the first edition. These books are comprised of 10 volumes, from ${\lceil}$volume 1${\rfloor}$to ${\lceil}$volum 8${\rfloor}$are internal medicine, ${\lceil}$volum 9${\rfloor}$ is gynecology, ${\lceil}$volum 10${\rfloor}$ is pediatrics. The contents are as follows; 'method of regluating astenia-syndrome' , 'diagnosis and treatment based on overall analysis of symptoms and signs on eight extra meridians', 'theory of Yang forms endogenous wind-syndrome', 'theory of spleen-energy rise up and stomach-energy descend', 'theory of stmach-Yeum', 'diagnosis and treatment based on overall analysis of symptoms and signs on collaterals'. Tian shi completed his work by compling the previous medical theories and through clinical studies. It is expected that his theories are effectively applied to improve clinical medicine.

문헌, 병증(病證)과 방제(方劑)에 근거한 반치법(反治法)에 대한 고찰

신순식,Shin, Soon Shik 대한한의학방제학회 2016 大韓韓醫學方劑學會誌 Vol.24 No.1

Objectives Based on related literature, cold and heat, deficiency and excess, true and false, and actually used formulas, paradoxical treatments presented in the 『Plain Questions of Inner Canon of Yellow Emperor』 including ‘treating pseudo-heat symptoms and real cold syndrome with cold herbs, treating pseudo-heat symptoms and real cold syndrome with cold herbs’ were analyzed.Methods Out of literature, paradoxical treatment related classics and papers were investigated and analyzed. Among diseases and syndromes, real cold syndrome with pseudo-heat symptoms, real heat syndrome with pseudo-cold symptoms, real deficiency syndrome with pseudo-excess symptoms, and real excess syndrome with pseudo-deficiency symptoms were reviewed. Among formulas, typical examples of the above mentioned paradoxical treatments were used as examples to analyze paradoxical treatments.Results Treating pseudo-heat symptoms and real cold syndrome with cold herbs is a method that uses herbs with cool and cold nature to treat real cold syndrome with pseudo-heat symptoms and Tongmaeksayeokgajeodamjeuptang is suitable for this method. Treating pseudo-cold symptoms and real heat syndrome with hot herbs is a method that uses herbs with warm and hot nature to treat real heat syndrome with pseudo-cold symptoms and Baekhogainsamtang is suitable for this method.Conclusions Based on the related literature, cold and heat, deficiency and excess, true and false, and actually used formulas examined as mentioned above, the paradoxical treatments presented in the 『Plain Questions of Inner Canon of Yellow Emperor』 are thought to be reasonable paradoxical treatments that fit the diseases and syndromes that actually appeared in our bodies.

고대(古代)의 한(韓).중(中).일(日) 의약교류(醫藥交流) -"일본서기(日本書紀)"를 중심으로

신순식,최환수,양영준,홍원식,Shin, Soon-Shik,Choi, Hwan-Soo,Yang, Young-Jun,Hong, Won-Sik 한국한의학연구원 1996 한국 한의학연구소 논문집 Vol.2 No.1

${\ulcorner}$Ilbonseogi${\lrcorner}$(edited A.D. 720) )was studied to investagate the medical and pharmaceutical exchange among ancient Korea, China and Japan. It seemed that Korean and Chinese traditional medicine was introduced to Japan through Korea. It was also shown in ${\ulcorner}$Ilbonseogi${\lrcorner}$ that Koreans who lived in china and Japan during that time seemed to hove active medical idea exchange. From various facts indicated in ${\ulcorner}$Ilbonseogi${\lrcorner}$, it was believed that Korean and Chinese traditional medicine was the basis for the foundation of Japanese traditional medicine.

한·중·일 동양삼국의 氣 학술 연구동향 분석 및 데이터베이스 구축

신순식(Soon Shik Shin),강희정(Hee Jung Kang),정용석(Yong Seok Chung),송광빈(Kwang bin Song),엄현섭(Hyun Sup Eom) 한국정신과학학회 2018 韓國精神科學學會誌 Vol.20 No.-

Most of research on Ki in the region of Asia(Korea·China·Japan) is concerned with human health, disease and bio-information. The study of health and bio-information in view of Ki is investigated through theoretical and practical methods for mediation, qigong, bio energy(life energy), psychic response and physical response. A tendency analysis of research group can prevent error in research experiments, and improve the efficiency of research by knowing previously tried methods. So we analyze the equipments and the “Ki-ology” trends of Asia(Korea Korea JungSin Science Association, China : Chinese Society of Somatic Science, Japan : International Society of Life Information Sciences(ISLIS)), and then established an electronic documentary journal for 3 countries in the form of a DB.