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외부 물질의 주입에 의해 발생한 이물 육아종의 임상 및 병리조직학적 고찰
심우행 ( Woo Haing Shim ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 大韓皮膚科學會誌 Vol.49 No.9
Background: Various foreign materials injected into the skin can cause foreign body granuloma, which can cause severe disfigurement. Objective: To describe the clinicopathological characteristics of injection-induced foreign body granuloma. Methods: We did a retrospective study of 27 cases of injection-induced foreign body granuloma. Factors investigated included sex, age, injected material, purpose of injection, operator who gave the injection, number of injections, onset time of the granuloma after the injection, affected parts of the body, cutaneous manifestations, associated symptoms, histopathologic findings, treatment modalities and clinical course. Results: The male-female ratio was 2 to 25. Twenty five patients received injection for cosmetic improvement and 2 patients for treatment of musculoskeletal disease. Twenty patients were treated by unlicensed practitioners. The injected materials were unknown in 14 cases, whereas silicone (n=5) was most common among known injected materials. On average, foreign body granuloma occurred 131.3±136.3 months after injection. The face was the most frequently affected site and usually presented as skin-colored or erythematous plaques. The histopathologic exam revealed variable infiltration of inflammatory cells, including lymphocytes, histiocytes, multinucleated giant cells, plasma cells, neutrophils, and eosinophils. A swiss cheese appearance was observed in 19 cases. Complete response was achieved in four patients: those who had been treated with surgical excision (n=2) and those treated with systemic corticosteroids with antibiotics (n=2). Conclusion: Foreign body granuloma can arise from injection of various foreign materials. Dermatologists should be aware of the clinical manifestations of injection-related foreign body granuloma to make an appropriate diagnosis and to provide proper treatment. Moreover, there should be great social concern about injection-related foreign body granuloma, because many cases are caused by unlicenced practitioners. (Korean J Dermatol 2011;49(9):801~808)
스파르가눔증 스파르가눔증 진단에서 초음파 검사의 유용성
진현주 ( Hyun Ju Jin ),문제호 ( Je Ho Mun ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ),김훈수 ( Hoon Soo Kim ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.12
Sparganosis is a kind of parasitic skin disease caused by sparganum, the plerocercoid larvae of the taper worm of the genus Spirometra. Sparganosis usually manifests as migrating or fixed subcutaneous nodules; therefore, it should be differentiated from lipoma, cysts, and cutaneous malignancies. Although the final diagnosis of sparganosis in humans depends on the identification of the worm in an infected tissue, suspicion for the presence of the parasite and careful history taking are important before making the diagnosis. However, it might be difficult for a clinician to suspect the existence of sparganosis because the incidence of this disease is extremely low. Therefore, an effective method for differentiating sparganosis from other skin disorders is needed. We suggest that ultrasonography could be an answer to this problem, on the basis of our experience of a case of cutaneous sparganosis in a 65-yearold woman showing very characteristic ultrasonographic findings. (Korean J Dermatol 2014;52(12):907∼910)
손발톱주위 사마귀에 대한 Bleomycin 병변내 주사요법 후 발생한 손발톱위축증 5예
김태욱 ( Tae Wook Kim ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.3
Onychatrophy is the processes in which the nail has initially formed satisfactorily and then shows total or partial regression. The causes of onychatrophy with pterygium include lichen planus, acrosclerosis, Stevens-Johnson syndrome, and cicatrical pemphigoid, and those without pterygium include severe paronychia, Stevens-Johnson syndrome, epidermolysis bullosa, and drugs. Bleomycin is an antitumor, antibacterial, and antiviral agent used in many dermatologic diseases such as warts, vascular anomalies, hemangioma, and cutaneous malignancies. Cutaneous adverse effects of bleomycin strongly depend on the route of administration and dosage. Bleomycin intralesional injection for periungual warts could result in permanent Raynaud phenomenon, nail dystrophy, and nail loss. We report five cases of onychatrophy following bleomycin intralesional injections for periungual warts. We remind that if bleomycin intralesional injection near the nail matrix is inevitable in recalcitrant periungual warts, the performer must manipulate precisely to avoid adverse effects. (Korean J Dermatol 2012;50(3):262~265)
특징적인 Dermoscopy 소견을 보이며 국소 Tacalcitol 치료에 의해 호전된 천공성 광택태선
심우행 ( Woo Haing Shim ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.12
Perforating lichen nitidus is an unusual variant of lichen nitidus. It is clinically characterized by umbilicated papules and histopathologically characterized by transepidermal elimination of inflammatory debris from granulomatous infiltrates. Most cases of perforating lichen nitidus are treated with topical corticosteroids, but long-term use of topical corticosteroids could provoke several side effects. Herein, we report a case of perforating lichen nitidus treated effectively and safely with topical tacalcitol ointment. We performed a dermoscopic examination for the perforating lichen nitidus lesion and found the characteristic frogspawn dermoscopic feature. (Korean J Dermatol 2011;49(12):1083~1086)
유향석 ( Hyang Suk You ),문제호 ( Je Ho Mun ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.7
Various modalities have been used for the treatment of psoriasis, including phototherapy. The choice of psoriasis treatment is based on the characteristics of the lesions, locations and amount of involved body surface area. Narrowband ultraviolet (UV) B therapy is a widely used and highly efficient method for psoriasis. But, large areas of unaffected skin may be irradiated along with the psoriatic lesions during phototherapy. The 308-nm excimer laser is a further development of narrowband UVB and was reported to be an effective and safe treatment for localized psoriasis. We experienced an excellent effect without significant adverse reactions of 308-nm excimer laser in a 9-year-old patient with palmoplantar psoriasis who was recalcitrant to oral cyclosporine and topical calcipotriol/ betamethasone treatment. (Korean J Dermatol 2013;51(7):527∼530)
김태욱 ( Tae Wook Kim ),김정원 ( Won Jeong Kim ),문제호 ( Je Ho Mun ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.3
Disseminated and recurrent infundibulo-folliculitis is an infrequent entity of unknown etiology that was first described in 1968, by Hitch and Lund. Most patient reports have been on young black male adults. It is rarely reported in Asian, and there has been only 1 case reported in the Korean medical literature in the year 1984. The syndrome has been characterized as tiny uniform, skin-colored papules similar to ``goose-bumps`` of skin. These papules predominantly involve the trunk and proximal extremities, and are usually accompanied by mild pruritus. In this report, we presented a 33-year-old man with a 10-year history of generalized skin-colored, follicular papules on the chest and back with intermittent pruritus. The clinical initial differential diagnosis included keratosis pilaris, lichen spinulosus, lichen nitidus, folliculitis, and disseminated and recurrent infundibulo-folliculitis. A histopathologic examination showed predominant mononuclear cell infiltration around the infundibular portion of hair follicles, follicular spongiosis and lack of hyperkeratosis. Herein, we reported a rare case of disseminated and recurrent infundibulofolliculitis with typical clinical and histopathological findings in a 33-year-old Korean man. (Korean J Dermatol 2013;51(3):202∼205