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고빈도 120 Hz 전침이 Carrageenan으로 유발된 흰쥐의 Prostaglandin E2와 척수 N-Methyl-D-Aspartate Receptor 발현에 미치는 영향
손인석,최병태,장경전,Son, In-seok,Choi, Byung-tae,Jang, Kyung-jeon 대한침구의학회 2003 대한침구의학회지 Vol.20 No.3
Objective : The role of high frequency 120 Hz electroacupuncture(EA) in carrageenan-induced pain was studied by examining the alnalgesic effects, and prostaglandin $E_2(PGE_2)$ levels measurement and spinal N-methyl-D-aspartate(NMDA) receptor expression. Inflammation was induced by an intraplantar injection of 1% carrageenan into the right hind paw. Method : Bilateral EA stimulation with 120 Hz were delivered at those acupoints corresponding to Zusanli and Sanyinjiao in man via the needles for a total of 30 min duration in carrageenan-injected rats. Results : EA stimulation showed significant analgesic effects as measured by analgesy-meter at all time points tested compared with controls. Three hours after carrageenan injection, PGE2 levels were measured by commercial kit. EA significantly inhibited PGE2 production in the right paw. The number of NR1 and NR2A, NMDA receptor, immunoreactive neurons was significantly increased in the superficial dorsal horn(laminae I-II) and nucleus proprius(laminae III-IV) of ipsilateral spinal cord at L4-5. But the number of carrageenan-induced NR1 and NR2A immunoreactive neuron, especially NR1 immunoreaction in the superficial dorsal horn, was reduced by 120 Hz EA stimulation. Conclusions : These results indicate that NMDA receptors may mediate transmission of nociceptive information originating in tissue inflammation of hind paw and high frequency 120 Hz EA stimulation have an alleviating action against local inflammatory pain.
이론적인 시트-인체 모델과 실차시험을 이용한 차량 승차감의 비교분석
손인석(In Suk Son),김정훈(Jung Hoon Kim),강연준(Yeon June Kang) 대한기계학회 2007 대한기계학회 춘추학술대회 Vol.2007 No.10
The purpose of this study compares human vibration on car seat through theoretical seat-human body model and vehicle test. Ride comfort has mostly been evaluated by the vehicle test, but it contains many problems such as weather, equipments and costs. The method using theoretical model for evaluation of ride comfort can complement these defects appearing in vehicle test. In this research, theoretical seat-human body model consists of 7 DOF, and acceleration values of this model are obtained entering measured excitation. Finally, ride values for 12 axis defined in BS 6841 were acquired in theoretical model. The theoretical results were found to agree well with experimental results. So the proposed method can be used for evaluating and improving ride comfort.
조태성,손인석,권혜연,윤현민,장경전,송춘호,안창범,서정철,Cho, Tae-Sung,Son, In-Suk,Kwon, Hae-Yon,Youn, Hyoun-Min,Jang, Kyung-Jeon,Song, Choon-Ho,Ahn, Chang-Beohm,Seo, Jung-Chul 대한약침학회 2001 Journal of pharmacopuncture Vol.4 No.3
Objective: The aim of this study was to assess the effect of CF herbal acupuncture for low back pain by Oswestry Disability Index Methods: Ten patients with back pain were selected and CF herbal acupuncture was administered one time per 5 days after admission. The degree of improvement was evaluated by Oswestry Disability Index and visual analogue scale(VAS). Oswestry Disability Index consisted of eleven items and they were scored as 5 or 6 points per one item. Results: All of the 10 patients, after CF herbal acupuncture, showed decreased score by Oswestry Disability Index and VAS. It means that the patient's satisfaction increased after treatment. Conclusion: These results suggest that the CF herbal acupuncture was effective for low back pain
동씨침(董氏鍼)을 가미(加味)한 치료(治療)가 중풍환자(中風患者)의 NIH Stroke Scale과 MBI상의 기능 회복에 미치는 영향
조태성,손인석,김철홍,서정철,윤현민,장경전,송춘호,안창범,Cho, Tai-sung,Son, In-seok,Kim, Cheol-hong,Seo, Jung-chul,Youn, Hyoun-min,Jang, Kyung-jeon,Song, Choon-ho,Abn, Chang-beohm 대한침구의학회 2002 대한침구의학회지 Vol.29 No.6
Objective : The aim of this study was to investigate the effect of tong's acupuncture on recovery of motor disorders in stroke patients. Methods : Twenty two patients with poststroke-hemiplegia were randomized into two groups. Ten patients(test group) treated by 2 methods-tong's acupuncture and body acupuncture. The other twelve patients(control group) treated only by body acupuncture. The activity of daily living was measured with a National Institutes of Health stroke scale(NlHSS) and Modified Barthel Index(MBI). The therapy was performed one a day for 2 weeks. Results: In terms of score of NIHSS. the test group showed statistically meaningful decrease after 2 week treatment. but the control group showed statistically meaningful decrease after I week(p<0.05). And in terms of score of MBI. the test group showed statistically meaningful increase after 2 week treatment. but the control group showed statistically meaningful increase after I week(p<0.05). There was no statistically meaningful difference after 1 and 2 week treatment between the groups. Conclusions: These results support that test group has almost same effectness compared with control group in improvement of the activity of daily living of poststroke-hemiplegic patients.
뇌졸중(腦卒中) 환자(患者) 형태(形態)에 관(關)한 임상연구(臨床硏究)
윤현민,안창범,송춘호,손인석,장경전,Youn, Hyoun-min,Ahn, Chang-beohm,Song, Choon-ho,Son, In-seok,Jang, Kyung-jeon 대한침구의학회 2003 대한침구의학회지 Vol.20 No.2
Clinical observation was made on 52 cases of Stroke that were confined through brain CT, MRI scan. The Stroke cases wee classified into the following kinds cerebral infarction, cerebral hemorrhage, cerebellar or brain stem infarction, cerebellar or brain stem hemorrhage. And among the 52 cases of Stroke cerebral infarction was noticed in 75.00%, cerebral hemorrhage in 11.54%, cerebellar or brain stem infarction in 9.52%, cerebellar or brain stem hemorrhage in 3.85%. The ratio between males and females was 1.74:1 in the whole groups of Stroke and most cases were over 60 of age. As the time of hospitalization, most patients hospitalized from 1 day after stroke to 7 days after stroke. And as the course of hospitalization, most patients hospitalized first. Among the preceding disease at the onset of Stroke hypertention was noted in 32.69%, and deabetes mellitus or heart problem was noted frequently(15.39%). Electrocardiography findings were as follows: The normal was noted in 53.85%, the abnormal in 46.15%. And as the abnormal, left ventricular hypertrophy was noted in 17.54%. The predisposing factors or conditions at the onset of brain infarction were usually initiated during the time of sleeping and those of brain hemorrhage chiefly during the time of exercising like overwork or walking etc. It was noted that smoking a pack of cigarette showed highest disease rate(33.33%) among the average of smoking amount of one day in case of man. Prior to attack, the most chiefly complain was dyspnea or discomfort on chest region. And 30.70% of patients had no previous sign. There were a large number of recurrent cases. The first attack was noted in 71.15%, the 2nd attack in 23.08%, the 3rd attack in 5.77%.