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      • SCOPUSKCI등재

        소아 균상 식육종 14 예의 임상 양상

        김상태,서기석,성재영 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.4

        Background: Mycosis fungoides(MF) is a representative of cutaneous T cell lymphoma and progresses through clinical stages, such as initial pre-mycotic(macule or patch), plaque, and tumor stage. MF is usually thought of as a disease of old adults, but it can develop at any age, including childhood. Despite the recognition that MF may occur in pediatric patients, there is scant 1iterature regarding clinical feature, histopathologic finding and prognosis specially related to childhood onset. The purpose of this study was to examine the clinical, histopathologic and follow up observation of MF in children, Methods: This study has been reviewed in the clinicopathologic findings of 14 MF patients who visited the Kosin University Gospel Hospital during about 10 years from January, 1991 to June, 2000. Results: 1. Duration of cutaneous lesions was from 6 months to 10 years, with mean duration of 3.6 years. 2. The morphology of skin lesions showed various features(pityriasis lichenoides-like, hypopigmented, hyperpigmented, ichthyosis-like, inflammatory linear verrucous epidermal nevus-like). 3. Histopathologic features revealed epidermotropism, a perivascular infiltrate in all cases, haloed lymphocytes, lymphocytes aligned in the basal layer, and coarse collagen in the papillary dermis in most cases. Pautrier's microabscess was shown in 3 cases (23%). 4. In T cell receptor γ gene arrangement using PCR (polymerase chain reaction), monoclonality was detected in 13 out of 14(93%). 5. Treatment including PUVA (psoralen and UVA), UVB, topical steroid agents and calcipotriol had good a response. 6. No patients had progressed to a more advanced disease. Conclusion: MF in children of this study showed a wide variety of skin lesions. Although no case of MF in this study progressed to a more aggressive status, MF in children should be carefully followed for development of more advanced cutaneous lesions and visceral involvement.

      • SCOPUSKCI등재

        하지절단 원위부에 발생한 림프부종을 동반한 우췌상 과증식증 1 예

        김상태,서기석,성재영,최태식,도기승 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.8

        Verrucous hyperplasia shows multiple warty like lesion on the amputation stump, but the pathologic findings of viral verrucae has not been discovered. A verrucous plaque on the amputation stump of the right leg was found in 31-year-old man. He had suffered from a traumatic amputation of right leg since 8 years ago. A leg prosthesis had been worn since that time. Histopathologic findings shows hyperkeratosis, acanthosis, papillomatosis, superficial dermal edema and dilated thick-walled venules oriented vertical to the skin surface. Verrucous hyperplasia was diagnosed with lymphedema on the basis of clinical and histological findings.

      • SCOPUSKCI등재

        판의 양상을 보인 융기성 피부 섬유육종

        김상태,서기석,장민수,성재영,최태식 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.8

        We report a case of plaque stage of dermatofibrosarcoma protuberans(DFSP). A 36-year-old female visited our clinic with a 10-year history of solitary deep seated palpable erythematous plaque on right anterior chest. There was no history of previous trauma at the site of the lesion. Histopathologic findings are characterized by a flat surface, lower cellularity and slender spindle-shaped neoplastic cells diffusely infiltrated dermis and subcutaneous tissue. The slender neoplastic cells have uniform nuclei with no evidence of cytologic atypia. Especially earlier plaque or nonprotuberans stage of the DFSP could be confused with benign lesions such as dermatofibroma or diffuse neurofibroma. Because plaque areas are strongly positive for CD34, this antibody is very helpful in differentiating other benign tumors.

      • SCOPUSKCI등재

        색소성 방추세포 모반 1예

        김상태,허준,서기석,성재영 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.12

        We report a case of pigmented spindle cell nevus which occurred in a 4-year-old male. Several months earlier, his mother noticed a 3×3mm sized annular, hyperpigmented macule on his right thigh. Histopathologic findings showed nests of spindle cells with sharply defined lateral margins in the dermoepidermal junction and cleft around the spindle cell nests with heavy melanin pigmentation.

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