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남관우 ( Kwan Woo Nam ),백명기 ( Myong Ki Baeg ),권정현 ( Jung Hyun Kwon ),조성훈 ( Soung Hoon Cho ),나수진 ( Soo Jin Na ),최명규 ( Myung Gyu Choi ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.5
tissue lymphoma. This study was to determine whether H. pylori was associated with colorectal neoplasms in Korean subjects undergoing routine checkup. Methods: A total of 10,082 subjects underwent routine checkups from January 2004 to April 2005. A H. pylori IgG test and stool occult blood test were included in the routine checkup program. Colonoscopy was performed if the stool occult blood test was positive or under subject request. Patients who underwent colonoscopy and had histologically confirmed cases of colorectal neoplasms were designanted as the subject group and those without as the control group. Results: Of the 10,082 subjects, 597 had full colonoscopy. The results identified 9 colorectal carcinomas and 118 adenomas. H. pylori seropositivity was identified in 6 (66%) subjects with colorectal carcinoma, 81 (68.6%) with colorectal adenoma and 248 (52.8%) controls. Subjects having colorectal neoplasms had a significantly higher H. pylori seropositivity rate compared with the controls (OR 1.94, 95% CI 1.28-2.95). This remained significant after adjusting for age, sex, body mass index, HbA1c and total cholesterol (OR 1.90, 95% CI 1.23-2.93). Patients with distal neoplasms also had a significantly higher H. pylori seroposivity rate (OR 1.88, 95% CI 1.17-3.01) which persisted after multivariate adjustment (OR 1.79, 95% CI 1.10-2.94). Conclusions: Subjects with colorectal neoplasms present an increased H. pylori seroprevalence compared with controls. (Korean J Gastroenterol 2013;61:259-264)
황현중 ( Hyunjung Hwang ),백명기 ( Myong Ki Baeg ),김범수 ( Pumsoo Kim ),김유진 ( Yu Jin Kim ),강석형 ( Seok Hyung Kang ) 대한소화기학회 2018 대한소화기학회지 Vol.72 No.4
Splenic abscess is a rare disease that generally occurs in immunocompromised patients. It is difficult to distinguish between splenic abscesses and cysts using imaging studies, especially if they are asymptomatic. A 50-year-old asymptomatic man who had received steroid therapy for underlying rheumatoid arthritis was referred to a university hospital due to presence of several splenic cysts, with the largest being 3.5 cm in diameter. Percutaneous aspiration was performed, and fluid analysis showed cysts infected by extended- spectrum, beta-lactamase-producing Escherichia coli. The patient was treated with ertapenem for four weeks, and the lesion disappeared on follow-up imaging studies. Splenic abscess should be included as a differential diagnosis of splenic cystic lesions in immunocompromised patients. (Korean J Gastroenterol 2018;72:209-212)
김혜원 ( Haewon Kim ),백명기 ( Myong Ki Baeg ),김지현 ( Jie-hyun Kim ) 대한내과학회 2019 대한내과학회지 Vol.94 No.5
Obesity is a critical target for public health interventions worldwide. There are many causes of obesity, and the importance of the gut microbiota in its pathogenesis has recently been recognized. The composition and function of the gut microbiota play a role in obesity and metabolic disease, yet the underlying mechanisms are unclear. Advances in our understanding of the link between obesity and the gut microbiota have suggested the potential of its manipulation for treating obesity. In this review, we summarize current knowledge of the interactions between the gut microbiota and obesity as well as the therapeutic potential of its modulation. (Korean J Med 2019;94:410-413)
반우호 ( Woo Ho Ban ),강현희 ( Hyeon Hui Kang ),백명기 ( Myong Ki Baeg ),김재경 ( Jae Gyung Kim ),김현진 ( Hyun Jin Kim ),백인운 ( In Woon Baek ),김은오 ( Eun Oh Kim ),고선혜 ( Sun Hye Ko ),이상학 ( Sang Haak Lee ),문화식 ( Hwa Si 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.70 No.4
Herein we report the case of a 71-year-old woman who complained of fatigue and enlarged right axillary lymph nodes for 18 months. At her first visit, her chest X-ray showed diffuse nodular opacities in both lung fields. Initial excisional biopsy of the axillary lymph nodes showed granulomatous lesions and acid fast bacilli were seen on Ziehl-Neelsen staining. However, even after 15 months of anti-tuberculosis (TB) medication, her right axillary lymph nodes were enlarged. We re-performed an excisional biopsy of the nodes, which showed Hodgkin`s lymphoma (HL). A retrograde review of the biopsy before anti-tuberculous medication, revealed HL coexisting with TB. HL and TB cause difficulties in differential diagnosis due to similarities in clinical course, imaging procedures and histopathological analysis of the involved tissue. Therefore, it is important to consider the possibility of concurrent HL and TB when patients who undergo treatment for TB or chemotherapy for lymphoma complain of persistent systemic symptoms or enlarged lymph nodes.
권태근 ( Tae Geun Gweon ),임철현 ( Chul Hyun Lim ),변성욱 ( Seoug Wook Byeon ),백명기 ( Myong Ki Baeg ),이종율 ( Jong Yul Lee ),문성진 ( Sung Jin Moon ),김진수 ( Jin Su Kim ),최명규 ( Myung Gyu Choi ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.6
Celiac disease is a chronic absorptive disorder of the small intestine caused by gluten. The prevalence rate of celiac disease is 1% in Western countries. But, it is rare in Asian countries, and there is no celiac disease reported in Korea. Here, we report a case of celiac disease. An 36-years-old woman complained non-specific abdominal pain and diarrhea. She had anemia and was taking medication for osteoporosis. Colonoscopy showed no abnormality except shallow ulcer at the terminal ileum. Gastroduodenoscopy showed micronodularity at the duodenum 2nd and 3rd portion. Capsule endoscopy and enteroscopy showed villous atrophy and blunting of villi from the duodenum. Small intestinal pathology showed villous atrophy with lymphocyte infiltration. After gluten free diet, diarrhea, abdominal pain, anemia and osteoporosis were improved. And, she felt well-beingsensation. This is a first case of celiac disease in Korea.
증례 : 순환기 ; 우관상동맥에서 기원하는 영양혈관을 갖는 거대 좌심방 점액종 1예
김혜강 ( Hye Kang Kim ),이동현 ( Dong Hyeon Lee ),권태근 ( Tae Geun Gweon ),송미애 ( Mi Ae Song ),백명기 ( Myong Ki Baeg ),김정호 ( Jeong Ho Kim ),전희경 ( Hui Kyung Jeon ) 대한내과학회 2010 대한내과학회지 Vol.78 No.1
심방 점액종은 심방 중격에서 발생하여 좌심방 혹은 우심 방으로 천천히 점진적으로 커지며, 대부분은 좌회선 관상동맥에서 혈관 공급이 이루어지나 우관상동맥에서의 혈관공급은 드문 일차성 양성 종양이다. 본 증례에서 저자들은 경·중등도의 호흡곤란을 주소로 내원한 여자 환자에서 관상동맥조영술을 통해 진단된 우관상동맥에서 기시한 거대 심장 종양의 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. A 55-year-old woman was referred to our hospital with a 6-month history of dyspnea (NYHA II-III). The physical examination revealed a grade 2/6 "tumor plop," i.e., a low-pitched sound heard during early or mid-diastole. The chest X-ray showed mild cardiomegaly with lung congestion in both lower lung fields. Two-dimensional echocardiogram showed a large myocardial mass, prolapsing into the left ventricle during diastole. Chest computed tomography showed a multi-lobulated mass (6.8×4.1 cm) attached to the interatrial septum during systole and prolapsing into the left ventricle during diastole. Coronary angiography demonstrated large tumor vessels arising from and surrounding the posterior lateral branch of the right coronary artery. The mass was excised and the patient recovered uneventfully. (Korean J Med 78:104-108, 2010)