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난치성 백반증에 대한 흡입물집을 이용한 비배양 표피세포이식술 20례
배정민 ( Jung Min Bae ),정한미 ( Han Mi Jung ),이한나 ( Han Na Lee ),이로우 ( Ro Woo Lee ),은성혜 ( Sung Hye Eun ),권혁선 ( Hyuck Sun Kwon ),이지혜 ( Ji Hae Lee ),김경문 ( Gyong Moon Kim ) 대한피부과학회 2018 대한피부과학회지 Vol.56 No.7
Background: As nonsurgical interventions for vitiligo are not always successful, various surgical modalities have been used in patients with refractory vitiligo. Of these, non-cultured epidermal suspension transplantation (NCES) was recently introduced to treat large recipient sites using cells from small donor tissue. Objective: We assessed the effectiveness and safety of NCES as a surgical treatment for patients with refractory vitiligo. Methods: We retrospectively reviewed 20 cases in 17 patients (11 females; median age 25 years) who underwent NCES from July 2015 through March 2018. Suction blisters (20 mm in diameter) were collected from the patient’s inner thigh at a donor-to-recipient area ratio of 1:5. After the addition of 5 mL recombinant trypsin solution to the suction blisters, followed by incubation at 37°C for 60 min, epidermal cells were manually scraped off the blister surface, and epidermal cell suspension was obtained by centrifugation at 1,500 RPM for 5 min. The suspension was applied to the vitiligo regions after epidermal ablation of those regions. Phototherapy resumed 1 month later. Treatment success was defined as ≥75% repigmentation of the surgical site, and all adverse events were noted. Results: Overall, 85.0% of cases (17/20) exhibited treatment success. Adverse events included hyperpigmentation (20%) and surgical site infection (5%), but the treatment was tolerable in all cases. Conclusion: NCES is a reliable surgical option for patients with vitiligo refractory to nonsurgical treatment. Large areas of vitiligo can be treated by NCES, and use of this technique should be encouraged in Korea. (Korean J Dermatol 2018;56(7):426∼432)
배정민(Jung Min Bae),이대형(Dae Hyung Lee),정기훈(Ki Hoon Jung) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.4
Necrotizing fasciitis is a progressive soft tissue infection involving the superficial fascia which can be a lethal disease without proper treatment. The predisposing factors of necrotizing fasciitis are diabetes mellitus, alcohol abuse, drug abuse, obesity, malnutrition and immunocompromised state. Most of the recently reported cases of necrotizing fasciitis were caused by perianal disease. We treated a young woman with necrotizing fasciitis secondary to infected bedsore who had been held in hospital for 15 years due to schizophrenia and epilepsy. Here, we emphasize the specific concern when treating patients with bedsore.
배정민 ( Jung Min Bae ),김세원 ( Se Won Kim ) 대한소화기학회 2009 대한소화기학회지 Vol.54 No.2
The stomach is the most frequent site of gastrointestinal stromal tumor (GIST). The common clinical manifestation of GIST are melena and hematochezia caused by gastointestinal bleeding. However, hemoperitoneum due to GIST rupture is a very rare condition. We describe a 33-year-old man with gastric GIST causing hemoperitoneum. A preoperative CT scan demonstrated large amount of fluid collection and extraluminal mass lesion in gastric antral area. He underwent an emergent laparotomy. The antral mass was polypoid shaped and showed ruptured focus. We performed a distal gastrectomy. The tumor was revealed as GIST with intermediate malignant risk by pathologic examination. The patient had an uneventful postoperative course and remains well. (Korean J Gastroenterol 2009;54:123-125)
배정민 ( Jung Min Bae ),김미연 ( Mi Yeon Kim ),박영민 ( Young Min Park ),김형옥 ( Hyung Ok Kim ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.5
Cement is increasingly used in the construction industry, however the occurrence of cement burns has rarely been reported. Exposure to wet cement may cause severe alkaline and thermal burns due to the exothermic reaction of calcium oxide with water which forms calcium hydroxide. Furthermore, alkalinity of calcium hydroxide in wet cement, combined with the effect of pressure and occlusion against skin, may result in cement burn. We herein report a case of cement burn in a 42-year-old male, who had wet cement trapped in his boots and presented with 3rd degree burns on both lower legs. He was treated with wet dressings and the burns healed after two weeks of treatment. (Korean J Dermatol 2006;44(5):586~588)