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배인규 ( In Gyu Bae ),정용근 ( Yong Geun Jeong ),마정은 ( Jeong Eun Ma ),이승준 ( Seung Jun Lee ),김현옥 ( Hyun Ok Kim ),김동욱 ( Dong Wook Kim ),박진용 ( Jin Yong Park ),조유지 ( Yu Ji Cho ),박동준 ( Dong Jun Park ),정이영 ( Yi Y 대한천식알레르기학회 2006 천식 및 알레르기 Vol.26 No.3
The usual reactions after an insect sting are mild redness and swelling at the stinging site, and the most serious reaction is anaphylaxis. There have been isolated reports of late- onset reactions, such as vasculitis, nephritis, neuritis, and serum sickness, occuring in association with an insect sting. Late-onset reactions, including serum sickness, occur much less frequently. We report 2 individuals who developed serum sickness reaction after bee stings. A 35-year-old male, a family member of beekeeper, had stung frequently. About 10 days after bee stings, he complained of fever, migratory polyarthralgia, erythematous skin rash, and myalgia. High levels of specific IgE to bee venom were detected by the radioallergosorbent test (RAST). The other patient was a 25-year-old male who presented with urticaria, angioedema, arthralgia, myalgia, fever, and skin rash about 7 days after a bee sting. He also had high titers of specific IgE to bee venom. We here report two cases of serum sickness reaction caused by bee stings. (Korean J Asthma Allergy Clin Immunol 2006;26:254-258)
류마티스관절염으로 오인된 Mycobacterium Marinum 감염에 의한 다발성 관절염
김현옥 ( Hyun Ok Kim ),배인규 ( In Gyu Bae ),허상택 ( Sang Taek Heo ),나재범 ( Jae Boem Na ),김재희 ( Jae Hee Kim ),강민규 ( Min Gyu Kang ),전대홍 ( Dae Hong Jeon ),김나영 ( Na Young Kim ),이상일 ( Sang Il Lee ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.2
Mycobacterium marinum (M. marinum) is a nontuberculosis mycobacterium that is normally associated with cutaneous lesions. Most cases occur after an individual has suffered minor trauma in association with contaminated fresh or salt water. In immunocompromised patients, M. marinum can cause osteomyelitis, synovitis and/or disseminated infection, which can be mistaken for rheumatoid arthritis (RA) or remitting seronegative symmetrical synovitis with pitting edema (RS3PE). Therefore, precise history taking and specimen culture are very important for early diagnosis and appropriate treatment. We report an unusual case of septic polyarthritis due to M. marinum that was diagnosed by culture and improved with antibiotic therapy.
고동한 ( Dong Han Ko ),배인규 ( In Gyu Bae ),윤태진 ( Tae Jin Yoon ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.10
Lues maligna (malignant syphilis), also called noduloulcerative syphilis, is a kind of cutaneous secondary syphilis, which presents virulent clinical features and is frequently associated with an immunosuppressed state. Though there are many possible debilitative diseases, it has recently been more frequently presented in the human immunodeficiency virus (HIV)-infected patients. Other causes are diabetes and chronic alcoholism. Prompt diagnosis and early treatment can result in a desirable recovery and prevent spread of the disease. We report two cases of lues maligna associated with the underlying diseases of HIV-infection and diabetes. The skin lesions in these cases showed favorable results after treatment with benzathine penicillin. (Korean J Dermatol 2006;44(10):1238~1241)
증례 : 감염 ; 다이어트 약물 치료 후 Candida guilliermondii에 의한 칸디다 혈증
임민희 ( Min Hee Lim ),허상택 ( Sang Taek Heo ),배인규 ( In Gyu Bae ),정용근 ( Yong Geun Jeong ),김현옥 ( Hyun Ok Kim ),고관수 ( Kwan Soo Ko ),김선주 ( Sun Joo Kim ) 대한내과학회 2009 대한내과학회지 Vol.77 No.2
최근 우리나라의 경우 다이어트에 대한 관심이 많아짐에 따라 검증되지 않은 다이어트 보조 약물을 복용하는 사례가 많은데 이러한 다이어트 약물을 복용하는 사람들에서 원인이 불분명한 발열 소견을 보일 때는 만약 다른 특별한 원인을 찾을 수 없을 경우 이러한 약물에 의한 면역 기능의 감소로 발생할 수 있는 전신 칸디다 혈증과 같은 기회 감염에 대해서 고려해 보아야 할 필요가 있을 것이다. 저자들은 면역기능에 특별히 이상이 없던 건강한 성인에서 다이어트 약물 치료 후 C. guilliermondii에 의한 전신 칸디다 혈증을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Candida guilliermondii is found in sea water, animal feces, buttermilk, and beer and has been isolated from human infections, mostly of cutaneous origin. It usually causes skin and soft tissue infections and has decreased susceptibility to fluconazole. Systemic infections occur mostly in immunocompromised patients. A 38-year-old female was admitted with a 4-day fever. Her cal and family histories were unremarkable, except for obesity. She had been taking diet pills for 3 months and had undergone injection therapy into her abdomen for lipolysis for 1 month. She did not respond to empirical antibiotics. A Candida species was isolated from blood cultures and identified as C. guilliermondii based on partial LSU rRNA gene sequence analyses. She was treated with amphotericin B, and recovered completely. (Korean J 77:251-254, 2009)
Load Flow 탐색 알고리즘을 적용한 부하차단 방지 시스템
이완석(Wan-Seok Lee),김병헌(Byeong-Heon Kim),이병창(Byoung-Chang Lee),배인규(In-Gyu Bae),주정민(Jeong-Min Joo) 대한전기학회 2021 대한전기학회 학술대회 논문집 Vol.2021 No.7
본 연구는 System Operater(SO, 급전원)에 의해감시·제어가 이루어지는 전력 시스템 운영의 신뢰성을 높이기 위해 SO의 전력계통 제어 시 자동화된 알고리즘을 SCADA에 적용해 제어의 신뢰성을 검증하는 방안에 대한 연구이다. 실시간으로 변화하는 부하의 흐름에 따라 전력시스템 운영을 변경하고 설비점검을 위한 정지 그리고 운전을 위해 SO는 빈도 높은 시스템 제어 업무를 수행하고 있다. 이 과정에서 판단착오 또는 단순 과실에 의해 정상적으로 공급중인 전력부하의 차단 개연성이 얼마든지 발생할 수 있는 현재의 시스템을 보완하기 위한 해결방안을 제시하고자 본 연구를 수행하게 되었다.
Vibrio vulnificus에 의한 급성 세균성 뇌수막염 1예
김현식 ( Hyeon Sik Kim ),허상택 ( Sang Taek Heo ),배인규 ( In Gyu Bae ),임민희 ( Min Hee Lim ),김재희 ( Jae Hee Kim ),윤성은 ( Seong Eun Yun ),김선주 ( Sun Joo Kim ) 대한내과학회 2010 대한내과학회지 Vol.78 No.4
연부조직 감염증과 패혈증을 동반하는 V. vulnificus에 의한 감염증은 치사율이 높은 중증의 감염 질환으로 12시간에서 24시간의 잠복기 이후 수일 이내에 사망하는 빠른 임상경과를 가진다. 본 증례는 연부조직감염이 동반된 패혈증의 소견은 전혀 관찰되지 않았던 예로서 전형적인 뇌수막염의 임상적, 검사실 소견과 함께 혈액에서 V. vulnificus가 배양되어 급성 세균성 뇌수막염으로 진단 후 적합한 항생제 치료로 완치된 경우이다. 문헌고찰 결과 V. vulnificus에 의한 급성 세균성 뇌수막염은 매우 드물고, 본 증례처럼 후유증 없이 호전된 것 또한 매우 드물다고 하겠다. Vibrio vulnificus infects susceptible individuals who eat contaminated seafood or have an open wound that is exposed to seawater. The common symptoms are necrotizing wound infection, primary septicemia, and gastroenteritis. A 52-year-old man visited the emergency department complaining of drowsiness. Based on a cerebrospinal fluid analysis, he was diagnosed with acute bacterial meningitis. V. vulnificus was isolated from a blood culture. The patient responded to treatment with ceftriaxone and ciprofloxacin. We report a rare case of acute bacterial meningitis caused by V. vulnificus that was treated successfully. (Korean J Med 78:523-526, 2010)
증례 : 감염 ; 보존적 치료로 호전된 시력소실을 동반한 급성 A형 간염 1예
임민희 ( Min Hee Lim ),허상택 ( Sang Taek Heo ),김차영 ( Cha Young Kim ),배인규 ( In Gyu Bae ),김재희 ( Jae Hee Kim ),천윤홍 ( Yun Hong Cheon ),하창윤 ( Chang Yoon Ha ) 대한내과학회 2011 대한내과학회지 Vol.80 No.2S
Hepatitis A is usually a mild, self-limiting illness, but in certain cases it can develop into a severe or fatal disease. The most common symptoms of acute hepatitis A virus (HAV) infection are fever, myalgia, nausea, vomiting, jaundice, and abdominal pain. Extrahepatic symptoms are rare, especially neurologic manifestations. We investigated a 34-year-old male who presented after suffering two days of fever, chills and general myalgia. His condition gradually deteriorated and he developed sudden blindness on day nine. This blindness lasted for 20 min and at this point abnormal brain images were observed. Initial tests for immunoglobulin M anti HAV were negative. These tests were repeated, later confirming acute HAV infection. After conservative management, the individual fully recovered. We report this extremely rare acute HAV infection case with metabolic encephalopathy exhibiting transient blindness. (Korean J Med 2011;80:S305-S309)
감염의 진단에 있어 Tc-99m Ciprofloxacin의 유용성
배인규,최선영,김양수,이미숙,오승준,류진숙,류지소,이희경,우준희 대한감염학회 2001 감염 Vol.33 No.2
Background : For the evaluation of infectious or inflammtory disease, Tc-99m HMPAO WBC scan has been used. But techniques involving radiolabelled leukocytes scan were difficult, and have failed to distinguish between bacterial infection and non-bacterial inflammation. To overcome this difficulty, we evaluated Tc-99m Ciprofloxacin in clinically suspected bacterial infection. Methods : We used this agent for 31 patients who had suspected sites of infection. And then we compared the imaging results of these patients with those of radiolabelled leukocyte scan. Results : There was no adverse effect. 29 patients was involved for the interpretation. Infective spondylitis was the most common suspected disease (41%). Bacteriologic culture was positive in 10 patients. The most common organism was meticillin-susceptible S. aureus (5 cases). The sensitivity and specificity of Tc-99m Ciprofloxacin was 83.3% and 66.6%, and those of Tc-99m HMPAO WBC was 62.5% and 83.3%, repectively. For the diagnosis of infective spondylitis the sensitivity of Tc-99m Ciprofloxacin was 80.0% and that of Tc-99m HMPAO WBC was 40.0%. Conclusion : Tc-99m Ciprofloxacin shows relatively high sensitivity and specificity. Tc-99m Ciprofloxacin was superior to Tc-99m HMPAO WBC for the diagnosis of infection in axial skeleton. (Korean J In-fect Dis 33:128∼132, 2001)