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박형진,홍은지,권효정,박성준,박주민,송근호,서경원,Park, Hyoung-Jin,Hong, Eun-Ji,Kwon, Hyo-Jung,Park, Seong-Jun,Park, Joo Min,Song, Kun-Ho,Seo, Kyoung-Won The Korean Society of Veterinary Clinics 2015 한국임상수의학회지 Vol.7 No.2
A 7-year-old spayed female Somali-cross cat was admitted with a 4-week history of anorexia, vomiting, weight loss, and lethargy. The cat was diagnosed with hepatic lipidosis. With intensive care and nutritional support via a nasogastric feeding tube for 3 weeks, the clinical signs of hepatic lipidosis were improved. However, skin lesions were found in the left and right scapular regions during the treatment that were suspected to be due to feline skin fragility syndrome (FSFS). Intensive wound healing therapy with granulated sugar, laser therapy, and a surgical flap was conducted. Skin lesions improved uneventfully without other clinical signs or recurrence of any skin lesion for a year. To our knowledge, this is the first report of a good prognosis in a hepatic disorder and concurrent FSFS. 7년령의 불임 암컷 소말리 교잡종 고양이가 4주 동안 지속된 식욕부진, 구토, 체중감소, 무기력을 주증으로 내원하였다. 환자는 지방간으로 진단 되었으며, 3주 동안 집중치료와 더불어 비위 영양관을 통해 유동식을 공급하였다. 치료기간 중, 지방간으로 인한 임상증상은 개선 되었지만 고양이 피부유약증으로 인한 것으로 의심되는 피부병변이 왼쪽과 오른쪽 어깨 부위에서 발견되었다. 과립당치료, 레이저치료 및 외과적 피판술을 통한 집중적인 상처 치유를 실시하였으며, 그 결과 환자는 다른 임상 증상이나 피부 병변의 재발 없이 성공적으로 치료되었다. 보고된 바에 따르면, 본 증례는 간질환과 고양이 피부유약증이 동반한 환자에서 좋은 예후를 보인 첫 번째 증례이다.
음이항회귀식을 이용한 도로표지의 인지반응시간 추정모형 개발
박형진,이기영,김정룡,Park, Hyung-Jin,Lee, Ki-Young,Kim, Jung-Young 대한인간공학회 2006 大韓人間工學會誌 Vol.25 No.4
The purpose of this study is to determine the economical standard of road signs by verifying the difference of driver's recognition and reaction time according to the space rate of letters on the road signs. For this reason, indoor simulations was conducted to confirm difference of recognition and reaction time on six sign-targets having different space rate. Also, a negative binomial regression model was used to find the main factors which could lower the rate of misreading. For this model, increasing of legibility of sign is not only simple enlargement of sign, but also suitable match of letters and sign. The result of this study is capable of verifying the importance of the space rate in road signs, and being utilized as a effective method to determine the standard of the road signs.
박형진,오원식,Ae-Na Park,Kyung-Rae Rho,Jong-Ho Shin,Yeongjeon Kim,Sung-Chan Jo 한국자기공명학회 2011 Journal of the Korean Magnetic Resonance Society Vol.15 No.1
We have performed Liquid Chromatography–Solid Phase Extraction–NMR (LC–SPE–NMR) analysis for liquid crystalline mixture and elucidated the structures of selected components by NMR spectra. Combining the results of one-dimensional 1H experiments as well as homonuclear and heteronuclear two-dimensional experiments, we could analyze the molecular structure of the liquid crystal singles whose structure had not been interpretable by mass spectrometry alone.
Molecular Identification of Adoxophyes orana complex (Lepidoptera: Tortricidae)in Korea and Japan
박형진,Ik Ju Park,So Young Lee,한경식,Chang Yeol Yang,부경생,박규택,Jong-wook Lee,조수원 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol.11 No.1
Species identification in the Adoxophyes orana complex has historically posed a problem, due to marked morphological similarities among the members. Although pheromonal studies have often been suggested as a better indicator for ecological distinctions among species than morphological similarities, no molecular proof has yet been provided in this regard. Here, we have sequenced the COI barcoding region (~660 bp) as well as another COI region (~940 bp) and 18S rDNA (~ (~1820 bp) for species in Korea and Japan. We determined that the specimens recently collected in Korea were A. orana, which is identical to the Japanese A. orana fasciata; the Korean A. honmai is identical to the Japanese A. honmai; the Korean Adoxophyes sp., which has previously been identified as A. orana in Korea, is not actually A. orana but a third, possibly new, species; and the Japanese A. dubia is identical to A. honmai in Japan and A. honmai in Korea. p-distances among the species and their phylogenetic trees are also provided herein. Species identification in the Adoxophyes orana complex has historically posed a problem, due to marked morphological similarities among the members. Although pheromonal studies have often been suggested as a better indicator for ecological distinctions among species than morphological similarities, no molecular proof has yet been provided in this regard. Here, we have sequenced the COI barcoding region (~660 bp) as well as another COI region (~940 bp) and 18S rDNA (~ (~1820 bp) for species in Korea and Japan. We determined that the specimens recently collected in Korea were A. orana, which is identical to the Japanese A. orana fasciata; the Korean A. honmai is identical to the Japanese A. honmai; the Korean Adoxophyes sp., which has previously been identified as A. orana in Korea, is not actually A. orana but a third, possibly new, species; and the Japanese A. dubia is identical to A. honmai in Japan and A. honmai in Korea. p-distances among the species and their phylogenetic trees are also provided herein.
듀얼 반응표면법을 이용한 V-그루브 GMA 용접공정 최적화에 관한 연구
박형진,안승호,강문진,이세헌,Park, Hyoung-Jin,Ahn, Seung-Ho,Kang, Mun-Jin,Rhee, Se-Hun 대한용접접합학회 2008 대한용접·접합학회지 Vol.26 No.2
In general, the quality of a welding process tends to vary with depending on the work environment or external disturbances. Hence, in order to achieve the desirable quality of welding, we should have the optimal welding condition that is not significantly affected by these changes in the environment or external disturbances. In this study, we used a dual response surface method in consideration of both the mean output variables and the standard deviation in order to optimize the V-groove arc welding process. The input variables for GMA welding process with the dual response surface are welding voltage, welding current and welding speed. The output variables are the welding quality function using the shape factor of bead geometry. First, we performed welding experiment on the interested area according to the central composite design. From the results obtained, we derived the regression model on the mean and standard deviation between the input and output variables of the welding process and then obtained the dual response surface. Finally, using the grid search method, we obtained the input variables that minimize the object function which led to the optimal V-groove arc welding process.
강원도 지역에 서식하는 무당개구리에서 생물학적 활성을 지닌 Bombesin 유사 Peptide 에 관한 연구
박형진,이윤렬,권혁일,김일,유일재,D . R . Marshak ( Hyoung Jin Park,Yun Lyul Lee,Hyeok Yil Kwon,Yil Kim,Il Je Yu,Daniel r . Marshak ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.3
The present study was performed to purify a BLI from the skin of frogs, B. orientalis inhabiting Kangwon-Do, Korea, and then determine its physiological activities and amino acid sequence. A substance that shows bombesin-like immunoreactivity (BLI) was partially purified from crude methanol extract of the frog skin by using a column of alkaline alumina and Sephadex G-10. BLI was further purified by using RP C18 preparative HPLC in which BLI was separated into 5 peaks. The major peak (BLI-K1) containing 65% of total BLI was subjected to purify as a single component by using sequential HPLC of SP-ion exchange and RP C18. Content of BLI in each fraction was monitored by RIA for which bombesin antiserum with a high titer and affinity to BBS was raised in a guinea pig. Eventually, 890 ㎍ of BLI-K1 was homogeneously purified from 420g of the skin of B. orientalis and it was not differentiated from synthetic BBS in RP C18, gel permeation and SP-ion exchange HPLC. In the physiological activities, BLI-K1 was identical to synthetic BBS in stimulation of gastrin release and exocrine pancreatic secretion including volume, protein, bicarbonate, amylase and chymotrypsin output in anesthetized rats. Furthermore, molecular weight and partial amino acid sequence of BLI-K1 was revealed to be identical to synthetic BBS. Therefore, it is concluded from the above results that the skin of B. orientalis contains the same BBS that has been isolated from the skin of European Bombina.
미생물이 고정화된 반응성 피복재의 유기물, 질소 및 인 용출 차단성능 평가
박형진,김영기,Park, Hyungjin,Kim, Young-Kee 한국물환경학회 2017 한국물환경학회지 Vol.33 No.4
This study aims to evaluate the effect of capping materials on blocking pollutant elution from contaminated sediment to water body. Experiments were carried out under conditions in which the elution rate was intensified artificially using compost with high concentration of organic compound and nutrient salts instead of sediments. Activated carbon (AC), modified activated carbon (MAC), P. putida immobilized activated carbon (PBAC) and effective microorganisms immobilized activated carbon (EBAC) were used as capping materials. Zeolite (ZT) and two kinds of commercially available microorganisms immobilized zeolite products (ZC, ZN) were used for comparison experiment. The elution rate of organic compound, nitrogen and phosphorus were compared with that of control experiment. The experiments were conducted for 56 days. Concentrations of chemical oxygen demand, total nitrogen, and total phosphorus were measured to use the comparison of release rate of organic compound, nitrogen and phosphorus. From the experimental results, AC based materials showed better performance to block the elution of organic compound and nitrogen than ZT based materials. Although ZT based materials were more effective than AC and PBAC to block phosphorus, MAC and EBAC showed the best performance of phosphorus elution blocking among the all candidate materials. In conclusion, EBAC is considered as the most effective capping materials, because organic compound, nitrogen and phosphorus will be degraded continuously by EM in the long term.