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朴相熙 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.1
Present study was carried out to determined the preferable approach for prevention of childhood tuberculosis, 117 cases of tuberculous meningitis who were admitted to the department of Pediatrics of Korea University Hospital during the period of 4 years from January 1974 to December 1978 were studied. The results obtained were as followings. 1. The annual incidence of patient was not decreased and which was consisted 3.3% of the total admission, however there was little dicreasement in 1978. 2. The highest age incidence was in the age of 2 to 5 years and 93.2% were under the age of 8 years, besides 24.8% were under 1 year of age. 3. The seasonal incidence in order of frequency were spring (32.5%) summer (26.5%), autumn (23.9%) and winter (17.1%). 4. One third (35.1%) of the patients were admitted to the hospital between 1-2 weeks after onset but 15.4% was more than 1 month. 5. At the time of admission, vomiting, convulsion fever and headach were the most common complaints. 6. During hospitalization clinically favorable responses were obtained in 63 cases (53.8%) and 6 cases (5.1%) died, but 27.4% were discharged against advice. Most of patients (87.2%) stayed in hospital less than 2 weeks, and more than half (54.7%) were discharged within 1 week of hospital day. 7. 29.1% out of 117 cases had the source of infection in family members and most of them both parents. 8. B.C.G. vaccination were vaccinated in 25.6% of the total patients and no one had the history of preventive therapy with INH. 9. The annual cost of preventive approach with INH was estimated as about ￦1,000 to ￦1,500 per infant. Because of the cost benefit, lost of follow up observation, side reaction of neural or hepatic damage and producing resistant strain of the bacteria, it is considered that B.C.G. vaccination is the preferable approach for prevention of tuberculous meningitis in childhood at the moment.
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두부 안면 형성에 미치는 Isotretinoin의 기형원적 효과에 관한 고찰
朴相熙,崔平和,全容赫 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.3
Isotretinoin, newly synthesized analog of vitamin A and prescribed for severe recalcitrant cystic acne, has recently proved to be implicated in human congenital malformation. Teratogenicity of a single dose of 200 ㎎/㎏ of this compound, administered orally to pregnant ICR mice on day 7.8 or 9 of gestation, on craniofacial development were investigated. Day 8 of gestation proved to be the most sensitive period to the drug; resorption rates were 46% and 88% of the treated embryos and 100% of litters developed malformations, such as microtia, hydrocephalus, agnathia/micrognathia, microglossia, anophthalmia, malformed CNS and facial dysmorphia; treatment on day 9 affected 9 litters out of ten and 75% live fetuses mostly on their paiate and ear auricle but normal range of resorption rate, whereas none of the fetuses, treated on day 7, were affected which indicate a strong evidence of developmental stage-dependent susceptibility to the drug and stagespecific pattern of malformation. The susceptibility to the drug on day 9 is more selective and limited, that is, 75% of fetuses treated on day 8 had multiple anomalies and 18% had a single, while the ratio was reversed on day 9. Skeletal defect/or hypogenesis usually coincided with those seen in external or section findings and defect of ear ossicles and tympanic ring usually associated with microtia. The results indicate that the malformation produced in human with fetal exposure to the drug can be induced in mice and in seems that the target of the drug at these stage of development might be neural crest and developing neuroepithelium.
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몇 가지 藥劑가 枇杷의 種子發芽 및 生長에 미치는 影響
朴相熹 圓光大學校大學院 1982 學位論叢 Vol.8-2 No.-
I made this experiment so as to enhance its coldproof charactor after promoting seed germination of loquats using chemicals of NAA, IAA, GA₃, Ethrel, and NaN0₃ The result is as follows: 1. Plant heights of NAA in 50ppm, IAA in 100ppm, GA₃ in 500ppm and Ethrel in 200ppm are high, compared with those of check plot. 2. Though the number of leaves in check plot is 6.0 and that of each area is more than one or two, the number of Ethrel in 500ppm is 10.4 and the differential variance of leaves is 4.4 more than the number of check plot leaves. 3. NAA in 50ppm reduced germination period to 7days, IAA in 100ppm to 10 days, GA₃ in 500ppm to 12 days, Ethrel in 200ppm to 9 days, and NaN0₃ in 2500 ppm to 12 days. NAA, IAA, GA₃, Ethrel, NaNO₃의 몇 가지 藥劑를 處理하여 枇杷의 種了發芽를 促進시켜 耐寒性을 높이고자 本試驗을 實施한 結果는 다음과 같다. 1) 草長은 NAA는 50ppm, IAA는 100ppm, GA₃는 500ppm區 Ethrel은 200ppm區에서 가장 促進되었다. 2) 葉數는 標準區가 6.0枚인데 處理區는 標準區보다 1~2區 많았으나 Ethrel은 500ppm에서 10.4枚로서 4.4枚가 더 많았다. 3 發牙日數는 NAA는 50ppm區에서 7日間, IAA는 100ppm區에서 10日間 GA₃는 500ppm區에서 12日間, Ethrol은 200ppm區에서 9日間, NaN0₃는 2500ppm區에서 12日間 促進되었다.
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施設園藝에 있어서 菜蔬의 品質向上을 위한 人工堆肥의 肥效에 關한 硏究
朴相熹,梁承列,陳英旭,丁蓮圭 順天大學校 1983 論文集 Vol.2 No.1
魚粉, 骨粉 및 기타 有機物로 構成된 人工堆肥의 施用이 葉根菜類의 生育에 미치는 影響을 究明하기 위하여 試驗을 遂行하였던 바, 그 結果를 要約하면 다음과 같다. 1. 人工堆肥의 施用은 배추의 球重과 무우, 당근의 根重을 현저하게 增加시켰다. 2. 배추의 球高나 葉數에는 人工堆肥 施用의 效果가 없었다. 3. 무우에 있어서 人工堆肥 施用이 生育初期의 根長과 地上部 生體重에 影響을 미치지는 못하나 根長의 差異를 나타냈다. 4. 당근에 있어서도 根長에는 有意性이 없었으나 根莖에는 有意性이 認定되었다. This study was carried out to investigate the effects of Artificial compost application on the growth of chinese cabbage, radish and carrot. The results were summarized as follows: 1. Artificial compost application promoted the weight of head of chinese cabbage, root weight of radish and carrot. 2. There were not differences between treatments on the height of head and No. of leaves in chinese cabbage. 3. Root diameter of radish was promoted by Artificial compost application, but was not promoted the root length and fresh weight and fresh weight of top on early growing stage. 4. In radish, there were non-significant on the root length, but were significant on the root diameter.
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공공기관 임원의 정치적 임명에 관한 연구 : 법제도 및 대통령의 영향을 중심으로
김병섭(金秉燮),박상희(朴相姬) 韓國行政學會 2010 韓國行政學報 Vol.44 No.2
공공기관 임원에 대한 정치적 임명(소위 ‘낙하산 인사’) 문제는 오랫동안 논란이 되어온 문제이나, 그 중요성에 비해 연구가 부족하다는 점에 주목하여, 본 연구는 1993년 2월부터 2009년 12월 사이에 임명된 공공기관 임원의 임명을 분석하였다. 즉, 소위 낙하산 인사를 줄이기 위해서 도입된 기관장 및 임원추천위원회 제도가 그 의도한 효과를 가져왔는지를 분석하였다. 결과 추천위원회라는 제도의 효과를 확인할 수 없었다. 반면, 최고정책결정자(대통령)의 교체는 공공기관 임원의 대표경력 변화에 유의미한 차이를 가져왔다. 이러한 결과를 통해 제도 그 자체도 중요하지만, 그 변화를 적극적으로 이끌어내는 행위자(대통령)의 역할이 중요함을 확인하였다.
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