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우리나라 만성 C형간염 환자에서 페그인터페론과 리바비린의 병합치료에 대한 효과
강명주 ( Myoung Joo Kang ),정은욱 ( Eun Uk Jung ),박상원 ( Sang Won Park ),최바울 ( Pa Ul Choi ),김지현 ( Ji Hyun Kim ),박성재 ( Sung Jae Park ),박은택 ( Eun Taek Park ),이연재 ( Youn Jae Lee ),이상혁 ( Sang Hyuk Lee ),설상영 ( Sa 대한간학회 2008 Clinical and Molecular Hepatology(대한간학회지) Vol.14 No.3
벼의 무기성분에 대한 양적형질좌 확인과 이온체 간 상호작용에 관한 연구
김경진 ( Gyeong-jin Kim ),이상범 ( Sang-beom Lee ),임성진 ( Sung-jin Lim ),이유지 ( Yu-ji Lee ),최근 ( Geun-hyoung Choi ),류송희 ( Song-hee Ryu ),이효섭 ( Hyo-sub Lee ),신중두 ( Jung-du Shin ),박용진 ( Yong-jin Park ),박상원 ( Sa 한국환경농학회 2019 한국환경농학회 학술대회집 Vol.2019 No.-
Minerals have been a subject of study in crops to solve nutrient and protein deficiencies as well as food safety problems. However, the interactions between functional minerals and toxic minerals, and their mechanisms have not yet been fully clarified. For this purpose, interactions among inorganic components were analyzed through ecotypes of a rice core population with diverse genetic characteristics in this study. Inorganic components in the rice core population were analyzed by inductively coupled plasma mass spectrometry (ICP-MS 7700E, Agilent Technologies, U.S.), and statistical analysis was conducted by SAS (Statistical Analysis System University Edition). In addition, candidate genes involved in functional minerals as well as Cd, As, and Pb were identified by genome-wide association studies (GWAS). In both non-contaminated and contaminated soils, interaction of inorganic elements was more active in Japonica than in Indica and Aus. Mg, Fe, Cu, Zn, Mn, Co, Ca and Na have a significant correlation at the p <0.01 level in both Japonica and Indica. In addition, quantitative traits loci for Mg, Fe, Cu, Zn, Mn, Co, Ca, Na and heavy metal were identified from GWAS results. According to the results of this study, interactions between functional and non-functional minerals with toxicity were dependent on ecotype. Therefore, further study is required on the genetic factors and their mechanism, which are specific interaction of the inorganic components in Indica and Japonica.