소승기탕(小承氣湯)으로 호전된 기분 장애 환자 1례

민준홍,임현택,Min, Joon-Hong,Lim, Hyeon-Taek 대한상한금궤의학회 2014 대한상한금궤의학회지 Vol.6 No.1

Objective : This case report evaluated the effect of Soseungki-tang(小承氣湯) on mood disorder. Methods : A patient of mood disorder was treated with Soseungki-tang(小承氣湯) in accordance with Shanghanlun(傷寒論) six meridian patterns diagnostic system. Results : After a series of Soseungki-tang treatment, the symptoms of mood disorder patient improved. Conclusions : According to Shanghanlun(傷寒論) six meridian patterns diagnostic system, this case study shows that Soseungki-tang is effective on mood disorder. However further clinical studies in depth are needed.

변병진단체계(辨病診斷體系)에 근거하여 회역산(回逆散)을 투여하여 호전된 우울증 1례

민준홍,Min, Joon Hong 대한상한금궤의학회 2015 대한상한금궤의학회지 Vol.7 No.1

Objective : This case report aims to show the effect of Huini-san on depressive disorder. the patient was diagnosed with Soeum-byung based on Shanghanlun provisions. Methods : According to Diagnostic system based on Shanghanlun provisions, the patient was diagnosed with Soeum-byung and the patients are treated with Huini-san. We evaluated the results of treatment by Korean Version of the Remission from Depression Questionnaire. Results : After taking Huini-san decoction for 2 month, the symptoms of patients improved Conclusions : This case report shows that effectiveness of using Huini-san according to Diagnostic system based on Shanghanlun provisions on depressive disorder.

『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 소시호탕(小柴胡湯)을 투여한 양명병(陽明病) 아토피 피부염 치험 1례

민준홍,조소현,Min, Joon-Hong,Jo, So-Hyun 대한상한금궤의학회 2015 대한상한금궤의학회지 Vol.7 No.1

Objective : This case report presents the effect of Soshiho-tang on Atopic Dermatitis. The patient was diagnosed with Yangmyung-byung based on Shanghanlun provisions. Methods : According to Shanghanlun six meridian patterns diagnostic system, we dianosed the patient as Yangmyung-byung and he had trouble getting out of bed and nighttime itch. The patient was treated with Soshiho-tang. We evaluated the results of treatment by Objective SCORAD Index and pictures. Results : After the treatment, Objective SCORAD Index decreased from 61 to 21.5. And he became to have no trouble in getting up and also nighttime itch vanished. Conclusions : This case report sowed and effectiveness of using Soshiho-tang according to Diagnostic system based on Shanghanlun provisions on Atopic Dermatitis.

대상포진 발병 후 발생한 난치성 소양증

민준홍 ( Joon Hong Min ),박지혜 ( Ji Hye Park ),최종원 ( Chong Won Choi ),이가영 ( Ga Young Lee ),박수홍 ( Soo Hong Park ),김원석 ( Won Serk Kim ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.4

Herpes zoster is an infective skin disease that is encountered commonly in dermatologic field. The best known complication of herpes zoster is postherpetic neuralgia (PHN). Also, many patients with herpes zoster experience neuropathic itch with or without pain. Those postherpetic itches (PHI) are rare, but some patients injure themselves by scratching skin with severe itching sensation, and with the loss of the protective sensation. So, PHI should be considered when evaluating a patient after an occurance of herpes zoster. Gabapentin has been successfully used to treat PHI in some cases. We report a case of postherpetic itch that has been successfully treated with gabapentin, as an unusual clinical presentation. (Korean J Dermatol 2012;50(4):337∼340)

미만성 피부 혈관종증

민준홍 ( Joon Hong Min ),서현민 ( Hyun Min Seo ),이현주 ( Heun Joo Lee ),박지혜 ( Ji Hye Park ),최종원 ( Chong Won Choi ),이가영 ( Ga Young Lee ),김원석 ( Won Serk Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.2

Diffuse dermal angiomatosis is an acquired, benign vascular proliferation with poorly circumscribed, violaceous, and livedoid plaques with frequent ulceration. Histologically, there is diffuse and interstitial proliferation of CD31- positive endothelial cells and myofibroblasts within the dermis. Endothelial atypia, mitoses, and vasculitis are lacking. Here we describe a 52-year-old male who presented with erythematous and purpuric patches on the trunk and lower extremities for 2 years. Histologic examination demonstrated a dense proliferation of endothelial cells in the papillary and reticular dermis. Small vascular spaces and extravasated erythrocytes were noted. Immunohistochemical staining using anti-CD31 antibody was positive. (Korean J Dermatol 2013;51(2):144∼147)

한국산 진달래과 식물에 관한 본초학적 연구

민준홍 ( Joon Hong Min ),김진호 ( Jin Ho Kim ),이숭인 ( Soong In Lee ),정종길 ( Jong Gil Jeong ) 대한본초학회 2013 大韓本草學會誌 Vol.28 No.4

Objectives : For the purpose of developing Korean herbalogy of the plants to Iridaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. Methods : The examined herbological books and research paper which published at home and abroad. Results : A list was made about Eriaceae plant which are cultivated or grew naturally in Korea, after investigate the data on domestic and foreign Eriaceae plants. Out of those lists, serviceable plants were selected and with those available plants, their distributions were analysed and parts which can be used as medicines were divided into 3 categories such as oriental medicine name, scientific name and non-official name. Eriaceae`s properties flavor, channels they use, effects, and toxicity were also noted. Eriaceae (grew in Korea) was divided into 9 classes with 48 species. Out of those, 3 classes with 14 species were found serviceable which indicates 29% of all. Out of all 48 specified Eriaceae plants, Rhododendron plants were found 26 species, which were shown the most. And 7 classes of Rhododendron plants were also selected the most in serviceable Eriaceae. Out of all serviceable parts in Eriaceae, leaf parts took first place as 12 species. Conclusion : There were totaled to 9 genera and 48 species in Iridaceae in Korea and among them medicinal plants are 3 genera, 14 species, some 29% in total.

『상한론(傷寒論)』 육경(六經) 진단체계에 근거하여 대양병(大陽病) 감초건강탕(甘草乾薑湯), 회역탕(回逆湯)을 투여한 과민성 방광 1례

이래춘,민준홍,Lee, Lae Chun,Min, Joon Hong 대한상한금궤의학회 2013 대한상한금궤의학회지 Vol.5 No.1

Objective : This case report aims to show the effect of Gamchogungang-tang, Hoiyeok-tang on an overactive bladder. The patient was diagnosed with Taeyang-byung based on Shanghanlun provisions. Methods : According to Diagnostic system based on Shanghanlun provisions, the patient was diagnosed with Taeyang-byung. So He was treated with Gamchogungang-tang, Hoiyeok-tang decoction for 70 days. We evaluated the results of treatment by Overactive Bladder Symptom Score(OBASS). Results : After taking Gamchogungang-tang, Hoiyeok-tang decoctions for 70 days, the patient's OBASS and symptoms was decreased from 12(severe) to 5(mile). Conclusions : This case report showed an effectiveness of using Gamchogungang-tang, Hoiyeok-tang according to Diagnostic system based on Shanghanlun provisions on overactive bladder.

공격성과 충동 조절 문제를 가진 자폐장애 환자 1례(例)에 관한 임상적 고찰

이성준 ( Seong-joon Lee ),민준홍 ( Joon-hong Min ) 대한상한금궤의학회 2011 대한상한금궤의학회지 Vol.3 No.1

Objective : The study was designed to report the clinical effects of herbal medicine on autistic disorder patient with aggression and impulse control problem. Method : The patient was treated with herbal medicine and evaluated by observation of parents and teacher. Results : By using herbal medicine, The patient's aggression and impulse control problem were significantly decreased Conclusion : This study shows that herbal medicine is effective on aggression and impulse control problem of autistic disorder patient. However, further clinical studies are needed.

피부 전이로 진단된 횡문근양 표현형을 동반한 대세포 폐암

서현민 ( Hyun Min Seo ),김정인 ( Jung In Kim ),김윤환 ( Yoon Hwan Kim ),민준홍 ( Joon Hong Min ),이승재 ( Seung Jae Lee ),박지혜 ( Ji Hye Park ),김원석 ( Won Serk Kim ),이가영 ( Ga Young Lee ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.4

Large cell carcinoma with a rhabdoid phenotype is very rare. We report the case of a 53-year-old man who presentedwith multiple nodules on the scalp, face, and trunk. A skin biopsy revealed large cell carcinoma with a rhabdoidphenotype throughout the dermis. Tumor cells had abundant cytoplasm, eccentric nuclei, and prominent nucleoliand did not adhere to each other. Immunohistochemical tests showed positive reactions for vimentin, epithelialmembrane antigen (EMA), and thyroid transcription factor-1 (TTF-1) and weakly focal reactions for pan-CK, CK7,and p63. Imaging studies and a percutaneous lung biopsy were performed and the results were consistent with alarge cell lung carcinoma with a rhabdoid phenotype. Based on these clinical and histopathological findings, weconcluded that his condition was a cutaneous metastasis from a large cell lung carcinoma with a rhabdoidphenotype, which occurs very rarely.

CDS 스프레드의 결정요인에 대한 연구

강장구 ( Jang Koo Kang ),민준홍 ( Joon Hong Min ),이창준 ( Chang Jun Lee ) 한국금융학회 2010 금융연구 Vol.24 No.2

CDS 스프레드는 회사채 스프레드를 대신하여 신용위험을 측정하는 대용치로 최근에 많이 사용되고 있다. 이에 본 논문에서는 CDS 스프레드의 결정요인에 대한 실증분석을 시도하였으며 연구의 주요 실증분석결과는 다음과 같다. 첫째, 각 회사별 CDS 스프레드 및 CDS 스프레드 차이에 대한 회귀분석에서 추정된 주요 설명변수 계수의 부호가 이론과 일치하였으며 이는 CDS 스프레드가 신용위험을 측정하는 좋은 대용치가 될 수 있음을 시사한다. 둘째, 설명변수 중에서 주가 변동성, 부채비율, 절대 매도-매수 스프레드, 외평채 CDS 스프레드의 설명력이 특히 높았으며 이들 변수만으로 회사채 CDS 스프레드의 약 95%를 설명할 수 있었다. 한편, 이들 변수는 CDS 스프레드 차이의 약 21%를 설명하였는데 이는 잡음(noise)이 있는 CDS 스프레드를 차분하면 설명력의 큰 감소가 발생한다는 Ericsson et al.(2009)의 연구결과와 일치한다. 셋째, 2008년 하반기에 발생한 금융위기를 기점으로 각 부표본에 대하여 회귀분석을 실시한 결과에서도 주요변수의 부호가 이론과 일치하여 이론에서 제시된 변수들의 설명력이 재확인되었다. Estimating and explaining the credit risk has long been a central research question in finance. Structural and reduced-form models are the two most popular approaches in credit risk literature. Both approaches have advantages and disadvantages: while explicitly explaining the mechanism of default, structural models do a poor job in explaining the prices of corporate bonds. On the other hand, the reduced-form models lack of economic rationale for determining the default process despite of the empirical success in pricing the corporate bonds. As an alternative, Collin-Dufresne et al.(2001) identify the determinants of the credit spreads from the structural models, and regress the credit spreads on these determinants to examine the explanatory power of these variables. Following the approach used by Collin-Dufresne et al. (2001), and employing credit default swap (CDS) spread as a proxy of credit risk, this paper investigates the determinants of CDS spreads by regressing the CDS spreadsin level (CDS) and spreads differences (?CDS) on the variables such as leverage ratio (Lev), equity volatilities (Vol), jump risk (Jumps), past stock returns (Ret), absolute bid-ask spread (Liq), risk-free rate (Macro), and CDS premium on foreign exchange stabilization bonds issued by Korean government (Macro). Specifically, we use the following regressions. CDSi,t=c(i)+β1(i,1)Lev(i,t)+β1(i,2)Vol(i,t)+β1(i,3)Jumps(i,t)+β1(i,4)Ret(i,t)+β1(i,5)Liq(,t)+β1(i,6)Macro(t)+ε(i,t), △CDS(i,t)=c(i)+βd(i,1)△Lev(i,t)+βd(i,2)△Vol(i,t)+βd(i,3)△Jumps(i,t)+βd(i,4)△Ret(i,t)+βㅇ(i,5)△Liq(,t)+βd(i,6)△Macro(t)+ε(i,t). Our main findings can be summarized as follows: First, the estimated signs for the explanatory variables are consistent with the theory, which justifies the use of CDS spread as a proxy for the credit risk. For example, while CDS spreads covary positively with equity volatilities, leverage ratios, absolute bid-ask spreads, the estimated signs for the past returns on stocks and risk-free rate are negative. Second, equity volatilities, leverage ratios, absolute bid-ask spreads, and CDS premium on foreign exchange stabilization bonds issued by Korean government are the most powerful variables: they account for approximately 95% of the CDS spreads, and explain 21% of the differences in CDS spread. The reduced explanatory power in difference regressions is consistent with Ericsson et al. (2009), who document that the maximum R2 is less than 100% given the presence of noise in the CDS data. Third, the estimated signs for the sub-sample regressions are also consistent with the theory. Sub-sample regressions are performed since the Chow (1960) test implies that there is a structural break in parameters in Oct 24, 2008 when the KOSPI 200 index declined more than 10%. Finally, the estimated coefficients of the volatility, leverage ratio, absolute spread, and CDS premium on foreign exchange stabilization bonds issued by Korean government remain positive when we investigate the stability of the regression coefficients over time using rolling-window regressions. The key distinction in this paper is that we use the credit default swap (CDS) spread as a proxy of the credit risk, while most researchers have used the corporate bonds in credit risk literature. The advantages of CDS spreads over corporate bond spreads are as follows. First, CDS spreads measure the credit risk better than corporate bond spreads because the CDS spreads are traded on standardized terms while corporate bond spreads varies from the coupon rates, seniorities. Second, CDS spreads are independent of the specification of risk-free rates. Finally, CDS spreads may better reflect the short-term credit conditions since it is known that the CDS spreads lead corporate bond spreads (Zhu, 2006). We perform the regressions using the CDS spread levels and CDS spread differences. While Campbell and Taksler (2003), Cremers et al. (2004) conduct the level regressions, Collin-Dufresne et al. (2001) perform the regressions in spread differences. Pedrosa and Roll (1998) argue that high R2 may be attainable with level regressions since the CDS spreads are highly persistent. However, given that the power of unit root test is quite weak, we conduct both regressions following Ericsson et al. (2009).