A Case of Encephalitis Caused by Epstein-Barr Virus Infection

Hyun-Jeong Do(도현정),Jong-Geun Baek(백종근),Jung-Sook Yeom(염정숙),Ji-Sook Park(박지숙),Eun-Sil Park(박은실),Ji-Hyun Seo(서지현),Jae-Young Lim(임재영),Chan-Hoo Park(박찬후),Hyang-Ok Woo(우향욱),Hee-Shang Youn(윤희상) 대한소아신경학회 2009 대한소아신경학회지 Vol.17 No.2

발열을 동반한 경련 이후 의식 저하를 주소로 내원한 환아에서 전형적인 전염성 단핵구증의 증상 및 비정형 림프구 혈증, 혈청학적 검사에서 양성 소견을 보여 EBV 감염에 의한 전염성 단핵구증의 합병증으로 발생한 뇌염으로 진단한 증례가 있어 보고하는 바이다. An 11-year-old girl was diagnosed with encephalitis due to Epstein-Barr virus(EBV). She was admitted to our hospital due to convulsion and decreased consciousness after several days of fever, sore throat and headache. Cerebrospinal fluid analysis showed lymphocyte-dominant pleocytosis and markedly elevated levels of protein. Magnetic resonance imaging(MRI) finding was normal, except for marked leptomeningeal enhancement. Even though she had signs and symptoms of infectious mononucleosis, EBV infection could not be considered as the underlying cause of the encephalitis until IgM for the viral capsid antigen of EBV had been detected in her blood. After treatment with acyclovir, a high dose of methylprednisolone and intravenous immunoglobulin, the neurological symptoms improved rapidly. She has not suffered from any neurological complications in the four months since being discharged. EBV infection should be considered as the main etiology in cases of childhood encephalitis, although there is no evidence of infectious mononucleosis existed.

곤륜(BL60) 자침 후 발생한 족부의 봉와직염 및 족관절 윤활막염: 증례 보고

도현정 ( Hyun Jeong Do ),이은주 ( Eun Ju Lee ),박경훈 ( Gyung Hun Park ),박윤령 ( Yun Leong Park ),서종철 ( Jong Cheol Seo ),김철홍 ( Cheol Hong Kim ),윤현민 ( Hyun Min Yoon ) 경락경혈학회 2021 Korean Journal of Acupuncture Vol.38 No.4

훈침 등 침 시술의 이상 반응은 대부분 경미하고 일시적인 경과를 보이므로 그 위험성을 간과하기 쉽다. 하지만 20만분의 1의 확률로 침 시술 이후 감염이나 신경계 손상 등의 심각한 합병증이 발생하며 이는 치명적인 경과로 진행하기도 한다. 따라서 시술후 이상반응이 발생할 시에는 예방적 차원의 적극적 처치를 고려하는 것이 합당할 것으로 사료된다. 본 증례 또한 자침 직후의 이상반응이 가벼운 동통으로 나타나며, 발생 당시 뚜렷한 피부증상을 확인하지 못하였으므로 그 위험성을 낮게 판단하여 진단 및 처치가 늦어진 사례로 볼 수 있다. 환자가 고령 혹은 만성 질환자로 염증을 발전시킬 수 있는 소인이 있는 경우 침첨이 피부를 자극하는 수준의 가벼운 자침을 시행하더라도 피부 상재균주에 의한 봉와직염 발생의 위험성이 높다. 따라서 반드시 시술 전 소독 등의 감염예방을 철저히 하고, 시술 후하지 및 족부에 발적이나 열감, 통증 등의 이상반응 발생 시 적극적인 양방 처치 또한 고려할 필요가 있다. 본 증례가 동료 임상의들의 주의를 환기시키는 데 도움이 되었으면 하는 바이다. The purpose of this study is to report a case diagnosed with cellulitis and ankle joint synovitis after acupuncture treatment. An 85-years old female suffering from low back pain was managed by acupuncture including BL60. After treatment, unintended ankle pain occurred. The pain was diagnosed with cellulitis and synovitis by MRI. The patient was transferred to the Western medical hospital, and ankle joint arthroscopic synovectomy was performed. It was difficult to find a clear relationship between acupuncture and ankle joint synovitis. But it would be reasonable to assume that cellulitis was associated with acupuncture needling and synovitis was followed. Serious adverse effects, such as septic arthritis, are rare, but need significant attention. For acupuncture treatment on the ankle, especially using BL60, the depth and manipulation should be carefully performed along with sterilization.

위장관 ; 건강한 20대 성인에서 Helicobacter pylori 감염과 십이지장의 위화생

서지현 ( Ji Hyun Seo ),도현정 ( Hyun Jeong Do ),박찬후 ( Chan Hoo Park ),우향옥 ( Hyang Ok Woo ),윤희상 ( Hee Shang Youn ),고경혁 ( Gyung Hyuck Ko ),백승철 ( Seung Chul Baik ),이우곤 ( Woo Kon Lee ),조명제 ( Myung Je Cho ),이광호 대한소화기학회 2013 대한소화기학회지 Vol.61 No.4

Background/Aims: Duodenal ulcers occur relatively frequently in adolescents, like in adults, and may relate to Helicobacter pylori infection and duodenal gastric metaplasia (DGM). This study investigated the association between H. pylori infection and DGM in healthy adults aged 20-29. Methods: Between 1995 and 2005, endoscopic biopsies of the duodenum, antrum and body were taken from healthy, young volunteers, who were first-year medical students, faculty staff, residents, and research assistants of Gyeongsang National University in Jinju, Korea. Urease tests were performed and the extent of DGM and histopathological grades according to the Updated Sydney System were determined. Results: In total, 662 subjects were enrolled (429 males and 233 females). The median age was 22.3 years. The overall incidence of DGM was 11.5% but DGM was more frequent in males (15.4%) than in females (4.3%) (p<0.0001). While H. pylori positivity rates changed significantly during the 1995-2005 period (p<0.01), the incidences of DGM did not. DGM was observed in 7.2% and 14.9% of subjects who were and were not colonized with H. pylori, respectively. DGM was also associated with less severe chronic gastritis and the absence of active gastritis in both the antrum and body, and the absence of follicles in the antrum (p<0.05). Conclusions: These findings suggested that DGM is not rare in healthy young adults and is unrelated to gastric H. pylori infection. (Korean J Gastroenterol 2013;61:191-195)

턱관절음양균형요법과 도침치료를 병행한 한방치료를 이용한 경부 근긴장이상증 치험 1례

박정현(Jung Hyeon Park),도현정(Hyun Jeong Do),정수은(Su Eun Jung),박송미(Song Mi Park),이영준(Young Jun Lee),김철홍(Cheol Hong Kim) 턱관절균형의학회 2020 턱관절균형의학회지 Vol.10 No.1

Objectives: The purpose of this study is to report the effect of Korean medical treatment with FCST and Miniscalpel- Acupuncture on patient with cervical dystonia. Methods: In this study, A patient with cervical dystonia was admitted to ○○ Korean medicine Hospital from Oct 20th, 2020 to Nov 28th, 2020. During the admission period, the patient was treated by Korean medical treatment (acupuncture, pharmacopuncture, herb medicine, etc.), especially using FCST and Miniscalpel-Acupuncture. The Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), the Tsui score and CDIP (Cervical Dystonia Impact Profile)-58 were used for measuring the Cervical Dystonia. Results: After treatment for 40 days, the TWSTRS showed a decrease from 52.75 to 13.75, the Tsui score also decreased from 17 to 3 and the CDIP-58 score decreased from 64.1 to 25.5. Conclusions: These results showed that Korean medical treatment especially using FCST and Miniscalpel-Acupuncture may have an effect on reducing symptoms of cervical dystonia. But the further researches are needed.

초극소 저체중 출생아에서 태반 병리와 신경발달의 예후 -예비적 경험

오성희 ( Seong Hee Oh ),김종재 ( Jong Jae Kim ),도현정 ( Hyun Jeong Do ),이병섭 ( Byong Sop Lee ),김기수 ( Ki Soo Kim ),김애란 ( Ai Rhan Kim ) 대한주산의학회 2015 Perinatology Vol.26 No.1

Objective: To investigate the relationship between placental pathology and neurodevelopmental outcomes among extremely low birth weight (ELBW) infants Methods: Pathology of placentas from ELBW infants born at a tertiary neonatal intensive care unit from January 2007 to December 2012 were reviewed and placental histology was grouped into 3 categories by a designated pathologist: acute chorioamnionitis (ACA), maternal vascular underperfusion (MVU), and control group. Matched ELBW infants were tested for significant neurodevelopmental delays defined as mental developmental index (MDI) or psychomotor developmental index (PDI) <70, using Bayley Scales of Infant Development-II (BSID-II). Results: The mean gestational age and birth weight of 175 infants were 27.1±2.5 weeks and 764.7±152.3 g respectively. Placental histology revealed MVU (48.0%), ACA (25.1%) and control (26.9%) in distribution. There were less significant patent ductus arteriosus in MVU group than in control group [adjusted odds ratio (OR)=0.331, P=0.011]. The frequencies of other neonatal diseases and mortality were similar in 3 groups. Sixty four of 175 infants were examined for BSID-II at mean corrected 19.9±3.2 months. MVU was associated with significant mental developmental delay (OR=5.185, P=0.036), but after adjustment for head circumference/weight at birth, the statistically significance of association disappeared (adjusted OR=4.391, P=0.075). ACA did not affect neonatal and neurodevelopmental outcomes. Conclusion: The result of placenta biopsy could be a useful tool in counseling parents for future neurodevelopmental outcome, however, further studies are required to define definitive association in between placenta biopsy and neurodevelopmental outcomes.

이상근증후군의 도침치료에 대한 체계적 문헌고찰 및 메타 분석

박송미 ( Song-mi Park ),정수은 ( Sue-un Jung ),박정현 ( Jung-hyeon Park ),도현정 ( Hyun-jeong Do ),조성우 ( Sung-woo Cho ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.2

Objectives This study was conducted to analyze the effect of using acupotomy for piriformis muscle syndrome. Methods The databases used for the search were PubMed, Embase, Cochrane library, China National Knowledge Infrastructure (CNKI), Koreanstudies Information Service System (KISS), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), KMbase, and National Digital Science Library (NDSL). The literature was searched using a total of 9 domestic and foreign databases. randomized controlled trial using only acupotomy as an intervention was selected. The selected studies are analyzed the risk of bias through Cochrane risk of bias, and meta-analysis was performed using Revman. Results As a result of meta-analysis of 11 selected studies, acupotomy was more effective than nerve block and acupuncture. In terms of visual analog scale and immediate analgesic effect, acupotomy did not have statistically significant results compared to other treatment methods. meta-analysis of electro-acupuncture and acupotomy showed no significant results. Conclusions When acupotomy is applied as a treatment for piriformis muscle syndrome, it is more effective than nerve block and acupuncture. but most of the studies have been judged as 'unclear' in the risk of bias assessment. Due to characteristics of treatment group and control group's intervention, It is judged that the blinding of the participant was not properly implemented. Therefore, it is considered that high-quality studies are necessary to supplement the problems in the future. (J Korean Med Rehabil 2021;31(2):25-40)