Bell's Palsy와 Ramsay Hunt Syndrome 환자군의 치료 기간에 따른 호전도의 비교 연구

김희철,김정호,김영일,Kim, Hee-Chul,Kim, Jeong-Ho,Kim, Young-Il 대한침구의학회 2008 대한침구의학회지 Vol.25 No.4

Objectives : The aim of this study is comparing the improvement of Bell's palsy and Ramsay hunt syndrome according to treatment duration. Methods : The 11cases diagnosed as Ramsay hunt syndrome and 30cases of Bell's palsy who visited Cheong-ju Oriental Medical hospital from February 2006 to June 2008 were evaluated. We used Yanagihara's unweighted Grading System to confirm the improvement. Results : In the analysis of cause, except the "none", the most common cause was "Overwork" in both two group. After 5-day treatment the score was getting worse but after 10-day treatment score was improved in both group. The improvement of Bell's palsy group was better than that of Ramsay hunt syndrome group after 5-day and 10-day treatment, but there was no significance. Conclusions : In comparison of Yanagihara's unweighted grading score checked before treatment, after 5-day, 10-day and 15-day treatment between Bell's palsy and Ramsay hunt sundrome, there was no statistical significant difference.

몬테카를로 시뮬레이션을 이용한 다면 공간의 조도계산

김희철,김훈,지철근,Kim, Hee-Chul,Chee, Chul-Kon,Kim, Hoon 한국조명전기설비학회 1993 조명.전기설비 Vol.7 No.6

In order to improve complicated construction and complex control which are didvantage of optimal PWM technique aimed at harmonic elimination method, this paper presented MRA(Mode1 Reference Adaptive) PWM technique that gating signal of inverter is generated by comparing the reference signal with the induced feedback signal at the reference model of load. Design of controller is composed of microprocessor and analog circuit. MRA PWM technique used in the paper is able to compensate the degradation of voltage efficiency to be generated by the ratio of the output voltage to the DC supply voltage being low for using conventional sinusoidal PWM technique. When the trapezoidal signal is employed as the reference signal. the low order harmonics of line current can be reduced and the switching pattern is made by on-line computation using comparatively simple numerical analysis. 본 논문에서는 몬테카를로 시뮬레이션을 이용하여 복잡한 다면 실내공간에서 조도분포를 예측하는 방법을 제안하였다. 광원으로부터 방사하는 빛을 배광분포에 따른 가중치를 가지고 진행하는 입자로 가정하였으며 광원에서 방출된 빛의 경로를 추적하여 반사면과의 교점을 구한다. 그리고 반사면의 반사율을 고려하여 이자가 반사 또는 흡수될 것인가를 판단하고 그 입자가 흡수될 때까지 입자의 진행을 반복한다. 무수히 많은 입자에 대해 위와 같은 과정을 반복하면 실내면의 조도분포를 얻을 수 있다. 보다 세밀한 측정을 위하여 각 실내면은 매우 작은 미소면적으로 분할하였다. 그리고, 실제공간에서도 응용될 수 있도록 실제의 공간과 유사한 다면 실내공간에 대해서 시뮬레이션을 하였으며, 조도분포에 따라 이차원의 등조도 곡선과 삼차원의 조도분포곡선을 그렸다. 실제로 모델공간을 제작하여 조도를 측정해 본 결과, 실험치와 계산치의 오차가 평균 2.3% 이내로 되었다.

곽령탕을 투여한 자가면역질환 환자 1례에 대한 임상적 고찰

김희철,이영수,유형천,Kim, Hee-Chul,Lee, Young-Soo,Ryu, Hyung-Cheon 대한한의학방제학회 2005 大韓韓醫學方劑學會誌 Vol.13 No.1

About the case of the patient who has diagnosed Systemic Lupus Erythematosus and admissed to our hospital from 27. January. 2005 to 28. February 2005, we could controll by herb medications userd differently patients-to-patients. SLE does not exactly correspond to any specific category of oriental medicine. But, according to previous reports, it can be controlled by oriental differential diagnosis of symptoms and signs. Because we diagnosed and treated her as at the point of Oriental Medicine and got the improvement, so we report. We think that the patient must get the screen test exactly and treat the disease proper ly, and if we apply this result to clinical cases at the point of Oriental Medical base from gathering and researching more cases, it will arouse sympathy-the excellence of Oriental Medicine and make the necessity of the further research and report from now on.

매괴화(玫瑰花) 잎, 줄기, 뿌리가 streptozotocin으로 유발(誘發)된 당뇨(糖尿)흰쥐에 미치는 영향(影響)

김희철,김정상,Kim, Hee-Chul,Kim, Jung-Sang 대한한방내과학회 1996 大韓韓方內科學會誌 Vol.17 No.1

This paper aims to probe the effect of Rosa rugosa, Thunbergii which streptozotocin induced hyperglycemic rats was examined by glucose contents, body weight, kidney weight and histological observation. The results obtained were as follows: 1. The glucose level is decreased in the adminstered group of the Rosa rugosa compared with control group. These effects are in order named root group, stem group and leaf group group. BUN is increased fold of 1.52 in the control group compared with normal group, but the administered group of Rosa rugosa are decreased., in order named leaf group, root group and stem group. 2. The kidney hypertrophy to body weight is the higest in the control group compared with the other group in rats, and glucose contents are in order named stem group, leaf group and root group. 3. The loss of body weight is the highest in the control group, and the loss is in order named stem group, leaf group and root group in rats. 4. In histological observations, pancreatic pancreatic islets of control group shows disrupted or condensed nuclei, and the intercellular space between acini are enlarged. In the experimental group, histological damages of the acini and pancreatic islet are recovered compared with control group. Thes results suggest that the extracts of Rosa rugosa are effected to diabetes mellitus, root extract correlated with the function of kidney, and leaf extract is decreased plasma glucose.

심부전(心不全)에의한 흉막삼출증(胸膜渗出症)으로 의심되는 환자(患者) 1례(例)에 대(對)한 임상적(臨床的) 고찰(考察)

김희철,이강녕,이동준,이영수,임진훈,이용운,김일렬,최창원,Kim, Hee-Chul,Lee, Kang-Nyung,Lee, Dong-Joon,Lee, Young-Soo,Lim, Jin-Hoon,Lee, Young-Yoon,Kim, Il-Ryul,Choi, Chang-Won 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.4

Pleural effusion is a state, retention of a mount of liquid in pleural cavity. Main causes of pleural effusion is Congestive Heart Failure that is caused by left ventricular heart failure. And that of Congestive heart failure is caused by increase of pleural capillary pressure or remain of effusion in pleural cavity. Bilateral venous pressure of pleura make worse pleural effusion and one way of venous pressure of that bring out pleural effusion. The purpose of this study is to examine the efficacy of oriental treatment for pleural effusion is caused by heart failure. One woman of 86 years old complained the symptom of general weakness, dyspnea, flank pain, anorexia, insomnia, coughing, secretion mixed blood. The symptom is caused by effusion that is brought out acute pneumonia, heart failure. At the time of Admission, in the diagnosis of Admission, in the diagnosis of Hyuneum(懸飮) she had taken Kungha-tang hap pleurisy-bang,(芎夏湯合助膜炎方), so improved dyspnea, flank pain, insomnia, coughing. In views of examination, decrease of heart failure' s symptom and pleural effusion. After 13days of admission, she had taken palmul-tang.(八物湯). As a conseguence of that, the symptom of general weakness. anorexia is improved and she was discharged.

건강한 기상을 위한 최적의 렘 수면기 알람기능 베개의 센싱 장치 개발

김희철,Kim, Hee-Chul 한국전자통신학회 2016 한국전자통신학회 논문지 Vol.11 No.2

사람은 하루 7~8시간 잠자는 동안 20~30번 자세를 바꿈으로 해서 최적의 수면 활동을 유지하려 한다. 최적의 수면을 제공하기 위해서는 베개 내부에 코골이 습관은 물론이고 개인의 수면 패턴을 감지할 수 있는 Sensing시스템과 Sensor에서 출력되는 정보를 분석 가공하는 프로그램 및 정보를 제공하는 디스플레이 장치를 통해 파악된 각종 수면 데이터를 효과적으로 활용하기 위한 센싱 장치의 개발이 필요하다. 본 논문에서는 수면 중 인 사람의 뒤척임을 감지해 수면 패턴을 분석하고 분석된 자료를 바탕으로 수면 건강에 대한 적극적인 관리 할 수 있는 웰빙 베개를 개발하고자 한다. People try to maintain optimal sleep activity to a changing attitude 20-30 times while sleeping 7-8 hours a day. In order to provide optimal sleep, we need to develop sensing device for apply effective various sleep data acquired through display device that can provide program and information which process and analyze information printed out from sensor and sensing system. In this paper, we analyze sleep pattern to detect the toss and turn while a person's sleeping and we develop a wellness pillow that can be active on sleep health management based on the analyzed data for sleep patterns.

파레토 및 어랑 형상모수에 의존한 수명분포를 따르는 소프트웨어 신뢰성 모형에 대한 신뢰도 특성요인 비교 연구

김희철,문송철,Kim, Hee Cheul,Moon, Song Chul 한국데이터전략학회 2017 Journal of information technology applications & m Vol.24 No.2

Software reliability is one of the most elementary and important problems in software development In order to find the software failure occurrence, the instantaneous failure rate function in the Poisson process can have a constant, incremental or decreasing tendency independently of the failure time. In this study, we compared the reliability performance of the software reliability model using the parameters of Pareto life distribution with the intensity decreasing pattern and the shape parameter of Erlang life distribution with the intensity increasing and decreasing pattern in the software product testing. In order to identify the software failure environment, the parametric estimation was applied to the maximum likelihood estimation method. Therefore, in this paper, we compare and evaluate software reliability by applying software failure time data. The reliability of the Erlang and Pareto life models is shown to be higher than that of the Pareto lifetime distribution model when the shape parameter is higher and the Erlang model is more reliable when the shape parameter is higher. Through this study, the software design department will be able to help the software design by applying various life distribution and shape parameters, and providing basic knowledge using software failure analysis.

1 포인트 드래그 연동 스마트 터치 제어용 다이나믹 모터 개발

김희철,Kim, Hee-Chul 한국전자통신학회 2015 한국전자통신학회 논문지 Vol.10 No.3

교육용 로봇은 과학의 기초 원리를 배우고 과학적 창의성을 키우는 것에 효과적인 교육 도구로 소개되면서 방과 후 학습에 적용되어 과학 교육을 위한 교육용 키트의 구성이 바뀌고 있다. 중소기업을 중심으로 과학적 창의성을 키우는 도구로서 다양한 교육용 로봇 기술과 학생들을 위한 다양한 범주의 게임로봇기술이 개발되고 있고, 기존의 mp3 음악이나 e-Learning 콘텐츠의 제공과 같이 로봇용 전문콘텐츠를 다운받아 학습에 활용하는 기술을 개발 중에 있으나 아직 전문 커뮤니티 형성이 미흡한 편이다. 현재는 사용자가 손쉽게 제어가 가능한 인터페이스 모듈용 모터가 개발이 되어있지 않아 1포인트 드래그 연동 스마트터치 제어용 다이나믹 모터 개발이 필요하다. Educational robot was introduced as an effective educational tool is to foster scientific creativity and learn the basic principles of science are applied to change the configuration of the educational after-school learning kits for science education. SMEs as a tool to foster scientific creativity center and a variety of educational robot technology and the wide range of games for students and robotic technology development, existing e-Learning by downloading mp3 music or learning content for the robot, such as the provision of specialized content Although the technology is still being developed to take advantage of the professional community formation is insufficient side. Currently, one-point linkage drag Smart Touch control dynamic motor development does not need this motor development is possible for users to easily.

보폐양영전(保肺養營煎)이 흰쥐의 기관지평활근(氣管支平滑筋) 장력(張力)과 면역에 미치는 영향(影響)

김희철,이강녕,Kim, Hee-Chul,Lee, Kang-Nyoung 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3

It has been reported that Bopheyangyoungjeon(BYJ) has an effect on deficiency asthma(喘虛) clinically. The aim of this study was to determine an appropriate dosage of BYJ to treat asthma. In order to study the effects of orally administered BYJ on allergic asthma, mice were pretreated with three oral doses of the herbal solution of BYJ before antigen sensitization. 2 days later Mice were actively sensitized with a subcutaneous injection of ovalbumin and 13 day later ovalbumin aerosols were used to provoke asthmatic reaction. Serum level of IgE, IL-4, WBC, RBC, HGB, cell numbers in bronchoalveolar lavage fluid(BALF), and in vitro isometric contractile responses of the isolated tracheal smooth muscle(TSM) to acetylcholine(ACh, 0.1-1000uM), KCl were measured. The results were as follows ; 1. Contractile responses of TSM to ACh significantly increased in C group at Ach 0.3, 1, 3, 10, 30, 100, 300, 1000uM(P<0.05, P<0.01) and increased in D at 0.1, 0.3, 3, 30, 30, 100, 300, 1000uM. 2. The sensitivity of TSM to Ach increased more in A, B group, but it was not significant. 3. The maximal contractile response of TSM to ACh decreased more significantly in C group(P<0.01) and D group(P<0.05) the control group. 4. The maximal contractile response of TSM to KCI decreased more significantly in B group and C group(P<0.001) than in the control group. 5. The counts of lymphocytes in BALF decreased more significantly in B group and D group(P<0.05) than in the control group. 6. The counts of macrophages in BALF decreased more significantly in B group, C(P<0.05) than in the control group. 8. Serum IgE level increased more significantly in B group and C group(P<0.05) than the control group. 9. The counts of WBC, RBC, HGB in blood increased more significantly in A group than the control group. The above results support a role for BYJ orally administered in treatment of deficiency allergic Asthma.

한국인 정신분열병 환자에서 항정신병 약물의 치료 반응과 도파민 D2, D3 및 D4 수용체 유전자 다형성

김희철,정성원,김대광,정철호,Kim, Hee-Cheol,Jung, Sung-Won,Kim, Dae-Kwang,Jung, Chul-Ho 대한생물정신의학회 2007 생물정신의학 Vol.14 No.3

항정신병 약물의 치료 반응을 예측해 줄 수 있는 유전자 지표를 찾기 위한 최근의 많은 약물유전학 연구들은 일관된 결과를 보고하지 못하고 있다. 본 연구는 항정신병 약물의 치료 반응과 도파민 D2, D3 및 D4 수용체 유전자 다형성과 관련성을 조사하였다. 연구 대상은 18~60세에 해당되면서 정신분열병의 DSM-IV 진단기준을 만족하고 본 연구에 대해 서면 동의한 국립부곡병원의 입원 환자 200명이었다. 연구는 대상자들의 입원 당시 병록지를 검토하여 후향적으로 이루어졌다. 대상자들은 퇴원할 당시를 기준으로 약물치료 반응 정도에 따라'반응군'과'비반응군'으로 구분되었으며 양군 사이의 도파민 수용체 유전자 다형성 차이를 비교하였다. 대상자 200명 중에서 188명(94%)이 비전형 항정신병 약물을 사용하였고 반응군은 141명(70.5%)이었다. 도파민 D2 수용체 유전자 Ser311Cys 다형성, 도파민 D3 수용체 유전자 Ser9Gly 다형성, 도파민 D4 수용체 유전자 exon III의 48개 염기반복 다형성에서 반응군과 비반응군 사이의 대립유전자 및 유전자형 빈도의 차이를 보이지 않았다. 결론적으로 본 연구에서는 항정신병 약물의 치료 반응과 도파민 D2 수용체 유전자 Ser311Cys 다형성, 도파민 D3 수용체 유전자 Ser9Gly 다형성, 그리고 도파민 D4 수용체 유전자 exon III의 48개 염기반복 다형 성과는 연관성이 없었다. 향후에는 단일의 항정신병 약물에 대한 전향적인 방법의 통제된 연구가 필요하다. Objectives:A considerable number of pharmacogenetic studies have been performed in recent years to define the association of antipsychotic drug response with dopamine receptor polymorphisms. The purpose of this study was to investigate the relationship between the therapeutic response to antipsychotic drugs and the polymorphisms of the dopamine D2, D3, and D4 receptor genes(DRD2, DRD3 and DRD4, respectively). Methods:We conducted retrospective chart review of 200 consecutively hospitalized patients with the diagnosis of schizophrenia(DSM-IV) who were treated with various antipsychotics(94% atypical antipsychotics) at Bugok National Hospital, Korea. The patients were divided into two groups, responders and non-responders, by responsiveness to antipsychotic drugs according to a four-point scale used in previous studies; responders included moderate to marked responded patients and non-responders included none to minimal responded patients. We analyzed the Ser311Cys polymorphism in the DRD2, the Ser9Gly polymorphism in the DRD3, and the exon III 48 bp repeat polymorphism in the DRD4. Results:Among the total patients of 200, 141(70.5%) were categorized as responders. There were no significant differences in the frequencies of the DRD2, DRD3, and DRD4 alleles and genotypes between responders and non-responders. Conclusion:These results suggest that the Ser311Cys polymorphism in the DRD2, the Ser9Gly polym- orphism in the DRD3, and the exon III 48bp repeat polymorphism in the DRD4 are not associated with the therapeutic response to antipsychotic drugs in Korean schizophrenic patients. A larger prospective study is needed to elucidate the association between antipsychotic response and dopamine receptor gene polymorphism.