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      • SCIESCOPUSKCI등재

        기계적 자극에 대한 백서 치주인대 섬유아세포의 변화

        김태균,김창성,조규성,채중규,김종관,최성호,Kim, Tae-Gyun,Kim, Chang-Sung,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2001 Journal of Periodontal & Implant Science Vol.31 No.2

        Periodontal disease is characterized by inflammation and subsequent loss and/or damage to tooth-supporting tissues such as bone, cementum,and periodontal ligament. Periodontal ligament and cementum are the key tissues in the initial process of regeneration following periodontal disease. Therefore, studies on cementoblasts, which form cementum are emphasized. It is still unclear which cells cementoblast differentiate from. This study was conducted under the hypothesis that PDL fibroblast can differentiate into either cementoblast or osteoblast depending on the conditions of surrounding tissue. Clinically, with excessive traction force of orthodontic appliances or excessive occlusion hypercementosis is observed, and this has been confirmed histologically. Consequently, activation of cementoblast can be expected in rats when mechanical stimuli are given to PDL fibroblast. Therefore, the purpose of this article is to prove that PDL fibroblast differentiates into cementoblast in rats under mechanical stimuli using histologic and molecular methods. In this study, twenty rats were given hard diet. Ten of them were sacrificed after 1 week, and the others were sacrificed after two weeks. Slides were made from tooth specimen, and they were studied under the microscope. In addition, PDL fibroblast and cementum from the extracted teeth were analyzed with Northern blotting. In histologic examination, as time passed, PDL fibroblast migrated to the dentin side, differentiated into cementoblast, and formed new cementum. In Northern blotting, it was found that mRNA expression of cementoblast-specific proteins such as BSP, OC, OPN, and type I collagen were more prominent in rats sacrificed after 2 weeks of hard-diet than rats sacrificed after 1 week. From these findings we can conclude that PDL fibroblast can differentiate into cementoblast under mechanical stimuli. We think that 'Rat Models' used in this study will be beneficial to future studies regarding cementoblast.

      • KCI등재

        수학사적 관점에서 오일러 및 베르누이 수와 리만 제타함수에 관한 탐구

        김태균,장이채,Kim, Tae-Kyun,Jang, Lee-Chae 한국수학사학회 2007 Journal for history of mathematics Vol.20 No.4

        베르누이가 처음으로 자연수 k에 대하여 합 $S_n(k)=\sum_{{\iota}=1}^n\;{\iota}^k$에 관한 공식들을 유도하는 방법을 발견하였다([4]). 그 이후, 리만 제타함수와 관련된 베르누이 수와 오일러 수에 관한 성질들이 연구되어왔다. 최근에 김태균은 $\mathbb{Z}_p$상에서 p-진 q-적분과 관련된 확장된 q-베르누이 수와 q-오일러 수, 연속된 q-정수의 멱수의 합에 관한 성질들을 밝혔다. 본 논문에서는 연속된 q-정수의 멱수의 합에 관한 역사적 배경과 발달과정을 고찰하고, 오일러 및 베르누이 수와 관련된 리만 제타함수가 해석적 함수로써 값을 가지는 문제를 q-확장된 부분의 이론으로 연구되어온 q-오일러 제타함수에 대해 체계적으로 논의한다. J. Bernoulli first discovered the method which one can produce those formulae for the sum $S_n(k)=\sum_{{\iota}=1}^n\;{\iota}^k$ for any natural numbers k. After then, there has been increasing interest in Bernoulli and Euler numbers associated with Riemann zeta functions. Recently, Kim have been studied extended q-Bernoulli numbers and q-Euler numbers associated with p-adic q-integral on $\mathbb{Z}_p$, and sums of powers of consecutive q-integers, etc. In this paper, we investigate for the historical background and evolution process of the sums of powers of consecutive q-integers and discuss for Euler zeta functions subjects which are studying related to these areas in the recent.

      • SCOPUSKCI등재

        동맥경화유발 토끼와 형질전환 마우스에서 산마늘 추출물의 항동맥경화 효과

        김태균,김승희,강석연,정기경,최돈하,박용복,류종훈,한형미,Kim, Tae-Gyun,Kim, Seung-Hee,Kang, Soeg-Youn,Jung, Ki-Kyung,Choi, Don-Ha,Park, Yong-Bok,Ryu, Jong-Hoon,Han, Hyung-Mee 한국생약학회 2000 생약학회지 Vol.31 No.2

        Atherosclerosis is emerging as one of the major causes of death in Korea as well as Western societies. In the present study; hypocholesterolemic and antiatherogenic effects of the ethanol extract of Allium victorialis Makino was investigated using the conventional rabbit and the cholesteryl ester transfer protein (CETP)-transgenic mouse model. Hypercholesterolemia was induced by feeding high cholesterol diet to the animals for 30 days and they were then fed with high cholesterol diet containing 0.5% of the A. victorialis extract for additional 30 (or 40) days. In the experiment using rabbits, treatment with the A. victorialis extract significantly decreased plasma total cholesterol, low density lipoprotein (LDL)-cholesterol, triglyceride levels and lipid peroxidation compared to those in the control group. Total cholesterol contents in the liver and the heart were also significantly decreased. Lipid staining of the aorta isolated from the rabbits showed that treatment with the A. victorialis extract decreased formation of atheromatous plaques on the intima of the aorta. In the experiment employing CETP transgenic mouse model, treatment with the A. victorialis extract decreased the levels of plasma total cholesterol and the tissue triglyceride levels in the heart. These results demonstrated that the ethanol extract of A. victorialis lowered serum cholesterol levels, tissue lipid contents and accumulation of cholesterol in the artery.

      • KCI등재후보

        초음파 비이컨을 사용한 이동로봇 실내 주행용 파티클 필터 SLAM

        김태균,고낙용,노성우,Kim, Tae-Gyun,Ko, Nak-Yong,Noh, Sung-Woo 한국전자통신학회 2012 한국전자통신학회 논문지 Vol.7 No.2

        본 논문에서는 파티클 필터 방법을 이용한 이동로봇의 SLAM(Simultaneous Localization and Mapping) 방법을 제안한다. 이동로봇의 SLAM은 지도가 주어지지 않는 환경에서 로봇 스스로 자신의 위치를 파악하는 것과 동시에 지도를 만드는 것이다. 제안된 방법은 로봇의 위치를 추정함과 동시에 특징점인 외부 비이컨들의 위치를 추정하는 방법을 다루고 있다. 특히 파티클 필터 방법을 적용하여 이동로봇과 특징점 위치를 파티클의 분포에 의해 확률적으로 표현한다. 제안된 SLAM방법은 이동로봇의 동작 뿐 아니라 특징점 위치의 불확실성을 고려한다. 따라서 매 샘플링 시각에 특징점의 위치 정보도 불확실성을 고려하여 예측되어진다. 제안된 방법의 성능을 시뮬레이션과 실험을 통하여 평가하였다. 제안된 방법은 비이컨으로 부터의 거리 정보에 불규칙한 잡음이 있는 환경에서도 실질적으로 사용가능한 지도 정보를 제공하였다. 또한 통상의 최소자승법이나 데드레크닝 방법에 비해서 보다 정확하고 강건하게 로봇의 위치를 추정하였다. This paper proposes a particle filter approach for SLAM(Simultaneous Localization and Mapping) of a mobile robot. The SLAM denotes estimation of both the robot location and map while the robot navigates in an unknown environment without map. The proposed method estimates robot location simultaneously with the locations of the ultrasonic beacons which constitute landmarks for navigation. The particle filter method represents the locations of the robot and landmarks in probabilistic manner by the distribution of particles. The method takes care of the uncertainty of the landmarks' location as well as that of the robot motion. Therefore, the locations of the landmarks are updated including uncertainty at every sampling time. Performance of the proposed method is verified through simulation and experiments. The method yields practically useful mapping information even if the range data from the landmarks include random noise. Also, it provides more accurate and robust estimation of the robot location than the usual least squares methods or dead-reckoning method.

      • KCI등재후보

        A note on the values of Euler zeta functions at positive integers

        김태균,J. Choi,Y. H. Kim 장전수학회 2012 Advanced Studies in Contemporary Mathematics Vol.22 No.1

        Recently, Euler zeta function is introduced by [수식]In this paper, we consider the values of Euler zeta function at positive integers.

      • KCI등재
      • SCOPUSKCI등재

        수종 생약재의 간염 B형 바이러스 증식 억제 활성 검색

        김태균,한형미,강석연,정기경,김승희,Kim, Tae-Gyun,Han, Hyung-Mee,Kang, Seog-Youn,Jung, Ki-Kyung,Kim, Seung-Hee 한국생약학회 1999 생약학회지 Vol.30 No.3

        This study was undertaken to test for anti-hepatitis B virus (HBV) activity of the aqueous extracts prepared from 9 medicinal plants of Korea (Cornus officinalis, Caesalpinia sappan, Rubus coreanus, Lycium chinense, Artemisia capillaris, Isatis tinctoria, Phyllanthus urinaria, Lysimachia christinae, Lonicera japonica). Aqueous extracts were tested for cytotoxicity and assayed for inhibition of HBV replication by measurement of HBV DNA and surface antigen (HBsAg) levels in the extracellular medium f HepG2 2.2.15 cells. The extract from Rubus coreanus, Artemisia capillaris, Phyllanthus urinaria decreased the levels of extracellular HBV virion DNA at concentrations ranging from 128 to $256\;{\mu}g/ml$ and inhibited the production fo HBsAg dose-dependently without showing cytotoxicity. Our findings suggest that these three hebal medicinal plants may have potential to develop as specific anti-HBV drugs in the future.

      • PSS 튜닝을 위한 기본 연구 PART II : PSS 실계통 최적 정수 선정을 위한 튜닝기법

        김태균,신정훈,윤용범,김동준,문영환,백영식,Kim, Tae-Gyun,Sin, Jeong-Hun,Yun, Yong-Beom,Kim, Dong-Jun,Mun, Yeong-Hwan,Baek, Yeong-Sik 대한전기학회 2000 전기학회논문지A Vol.49 No.7

        Based on the results in the first-part paper, PSS tuning methods including the determination of PSS gain and compensation of phasor lagging are investigated in this second part. In the phase compensation, PSS should compensate phase lagging, resulted from power system-generator-excitation system loop, to provide damping torque in equal phase with the generator speed. Also, PSS gain should be determined to provide maximum damping torque as much as possible without the other modes unstable. In this paper, gain tuning method using the root-locus and the phase compensation of PSS at the one machine with infinite bus system are presented. The differences between PSS tuning at the tuning condition and at the least-stable condition are also discussed.

      • KCI등재

        유체$\cdot$구조물 상호 작용 기법을 이용한 오일 펜스의 변형 예측

        김태균,김욱,허남건,Kim T. G.,Kim W.,Hur N. 한국전산유체공학회 2000 한국전산유체공학회지 Vol.5 No.3

        In the present study a method of computing fluid-structure interaction is presented to simulate the deformation shape of an oil fence which is used to contain or to divert the split oil in sea water. The computation is performed by taking into account of the force and moment balance in each computational element of the oil fence. The forces and moments acting on each element of the structure is computed from the flow analysis, which in turn is used to predict deformed shape of the structure until the procedure converges. The flexibility of the oil fence was also considered in the analysis. It is shown from the present study that the predicted deformed shapes agree quite well with the available experiment data.

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