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비전형적인 세침흡인 세포학적 소견을 보인 후복막강 부신경절종 - 1례 보고 -
김진아,김영신,강창석,이안희,김병기,심상인,김선무,Kim, Jean-A,Kim, Young-Shin,Kang, Chang-Suk,Lee, An-Hi,Kim, Byung-Kee,Shim, Sang-In,Kim, Sun-Moo 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.1
A case of retroperitoneal paraganglioma is presented with fine needle aspiration cytologic features. A 57-year-old woman complained of abdominal discomfort and left flank pain for 2 years. The abdominal CT scan revealed an ovoid mass left to the abdominal aorta. Percutaneous fine needle aspiration was performed from the mass. The smear revealed cellular sheets or groups on hemorrhagic background. The tumor cells were ovoid, round to spindle shaped with mild to moderate cellular pleomorphism. The nuclei were round to ovoid and had evenly dispersed chromatin and small nucleoli. The cytoplasm was amphophilic, finely granular and poorly defined. Cells having large or spindle nuclei were quite frequently observed, however, mitosis was not present The cytologic findings suggested paraganglioma, but the frequent spindle cell pattern and the pleomorphism made it difficult to exclude other endocrine tumors and sarcomas. The clinical, histological and ultrastructural findings as well as cytologic findings contributed to confirmatory diagnosis.
뺨 점막에 발생한 충실성 선양낭성암종의 세침흡인 세포학적 소견 - 1예 보고 -
김진아,김영실,이안희,심상인,김병기,김경미,Kim, Jean-A,Kim, Young-Sill,Lee, An-Hi,Shim, Sang-In,Kim, Byung-Kee,Kim, Kyoung-Mee 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.2
Adenoid cystic carcinoma constitutes 4 percent of ail benign and malignant epithelial salivary gland tumors and is a highly malignant tumor of the salivary glands. The cytologic presentation in aspirates is usually characteristic with spherical clusters(balls) of small tumor cells filled with hyaline material. But in case of the poorly differentiated variety(solid type), it is difficult to differentiate from other tumors because sheets of small, fairly monotonous malignant cells, with somewhat larger and more conspicuous nuclei are only seen. The cytologic findings of fine needle aspiration of solid type adenoid cystic carcinoma of buccal mucosa in a 51-year-old man are presented. On cytologic findings, solid sheets of monotonous tumor cells with focal necrosis was noted on a hemorrhagic background and the characteristic cytologic features of adenoid cystic carcinoma was absent.
김진아,김영실,이안희,심상인,김병기,김경미,Kim, Jean-A,Kim, Young-Sill,Lee, An-Hi,Shim, Sang-In,Kim, Byung-Kee,Kim, Kyoung-Mee 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.1
Pulmonary hamartoma is an uncommon benign tumor consisting of a mixture of loose fibromyxoid tissue, cartilage, fat, and cleft-like spaces lined by cuboidal or ciliated epithelium. Cytologically, the presence of a mesenchymal component is essential for the diagnosis of pulmonary hamartoma. We report the fine needle aspiration cytologic findings of two cases of pulmonary hamartoma. Case 1 was a 71-year-old woman with a mass, measuring $1.8{\times}1.5cm$ in the upper lobe of the right lung. Case 2 was a 51-year-old woman with a mass, measuring $2.3{\times}2.0cm$ in the lower lobe of the right lung. Fine needle aspiration cytology of both pulmonary masses revealed several sheets of loose fibromyxoid tissue fragments with focal cartilaginous differentiation and a few clusters of bland cuboidal epithelial cells on the bloody background. The diagnosis was histologically confirmed by needle biopsy.
김민정 ( Min Joung Kim ),김사진 ( Sa Jin Kim ),정문영 ( Moon Young Jeong ),김진휘 ( Jin Hwi Kim ),이연정 ( Yun Jung Lee ),김은중 ( Eun Jung Kim ),김진아 ( Jean A Kim ),서경윤 ( Kyoung Yun Seo ),박종섭 ( Jong Sup Park ),허수영 ( So 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.12
Although parovarian cysts constitute 10-20% of all adnexal masses, malignant parovarian tumors are extremely rare. Due to the rarity of this lesion, there are controversies concerning the origin, clinical behavior, and prognosis of these tumors. Currently
류마티스 관절염 양상으로 발현된 Churg-Strauss 증후군
김홍기 ( Hong Gi Kim ),박성환 ( Sung Hwan Park ),최민호 ( Min Ho Choi ),강미자 ( Mi Ja Kang ),고동훈 ( Dong Hoon Ko ),조철수 ( Chul Soo Cho ),김호연 ( Ho Youn Kim ),김진아 ( Jean A Kim ) 대한류마티스학회 1998 대한류마티스학회지 Vol.5 No.1
Churg-Strauss syndrome (CSS) or allergic angiitis and granulomatosis is a disorder characterized by pulmonary and systemic small-vessel vasculitis, extravascular granulomas, and hypereosinophilia. It occurs in individuals with asthma and allergic rhinitis. The diagnosis of CSS is made on the basis of clinical and pathologic features. According to 1990 American College of Rheumatology(ACR) criteria for the classification of CSS, 6 criteria were developed. The presence of 4 or more of these criteria yielded a sensitivity of 85% and a specificity of 99.7%. We describe a case of CSS in a 62-year-old female who met all of 1990 ACR criteria, but presented as like a as rheumatoid arthritis initially. Clinical symptoms, laboratory and roentgenographic findings gradually responded to high dose prednisolone treatment and resolved 3 weeks later. After discharge, she has been treated with oral prednisolone in a tapering course. Although polyarthritis with eosinophilia, vasculitis, and neuropathy are clinical manifestations of rheumatoid arthritis, those maniestations frequently occur during the vasculitic phase of the CSS. This case suggests that thorough differentiation of extra-articular manifestations of RA from clinical manifestations of CSS is considered when we meet a patient who have polyarthritis and vasculitis.
조근종 ( Keun Jong Cho ),김진수 ( Jin Soo Kim ),김창환 ( Chang Whan Kim ),김재광 ( Jae Kwang Kim ),한석원 ( Sok Won Han ),정인식 ( In Sik Chung ),김진아 ( Jean A Kim ) 대한내과학회 2006 대한내과학회지 Vol.71 No.5
유암종은 장크롬친화성 세포에서 발생하는 비교적 드문 내분비 종양으로 그 중 위유암종은 위내시경 검사의 증가로 발생률이 점차 증가하고 있다. 위유암종은 고가스트린혈증을 동반한 만성 자가면역성 위축성 위염이나 가스트린종에 동반된 경우에 대부분 다발성이며, 예후는 고가스트린혈증이 없이 단일 종괴를 형성하는 경우에 비하여 양호하다. 위유암종은 흔히 내분비질환이나 다른 종양에 병발하나 자가면역성 위축성 위염 외에 자가면역성 질환에 동반되는 예는 드물다. 쇼그렌 증후군은 주로 타액선을 침범하는 자가면역성 외분비병증으로 거의 모든 장관을 침범할 수 있으며 만성 위축성 위염은 가장 흔히 동반되는 위장관계 질환으로, 이로 인한 고가스트린혈증과 창자크롬친화세포의 과형성으로 유암종이 발생할 수 있으나 국내외적으로 아직까지 이에 대한 보고는 없다. 저자들은 44세의 여자 환자에서 쇼그렌 증후군에 동반된 다발성 위유암종을 1예 경험하였기에 문헌고찰과 함께 보고하는 바이다. Carcinoid tumors are rare endocrine neoplasms arising from the enterochromaffin or enterochromaffin-like cells. Gastric carcinoids associated with autoimmune atrophic gastritis and hypergastrinemia, are usually multiple and the prognosis are better compared to solotary lesions with out hypergastrinemia. Gastric carcinoids are commonly associated with other endocrine disorders or tumors, but any associations with autoimmune disorders other than autoimmune atrophic gastritis have rarely been reported. Sjogren`s syndrome is an autoimmune exocrinopathy that primarily affects the salivary glands, but it can also involve almost any other part of the gut. The most common form of gastrointestinal involvement in Sjogren`s syndrome is chronic atrophic gastritis, which can lead to hypergastrinemia and the subsequent development of carcinoid. However, gastric carcinoid tumor associated with Sjogren`s syndrome has not yet been reported on. To the best of our knowledge, this is the first such case in the world. We report on this case along with review of the related literature.(Korean J Med 71:551-557, 2006)
소아의 견갑골에 생긴 투명세포연골육종 - 1예 보고 -
이경지,이안희,김진아,김형민,이교영,Lee, Kyung-Ji,Lee, An-Hi,Kim, Jean-A,Kim, Hyoung-Min,Lee, Kyo-Young The Korean Musculoskeletal Tumor Society 2009 대한골관절종양학회지 Vol.15 No.2
투명세포연골육종은 모든 연골육종의 2%를 차지하는 매우 드문 저등급성 종양이다. 주로 긴뼈의 뼈끝에서 발생하며 대퇴골과 상완골의 근위부에서 가장 흔하고, 견갑골을 포함한 납작뼈에는 드물다. 25-50세 사이의 연령에서 호발하며, 20세 이전의 발생은 흔치 않다. 조직학적으로 종양 세포는 소엽상 무리를 지어 관찰되며, 투명하고 풍부한 세포질을 특징적으로 가진다. 저자들은 8세 여아의 견갑골에서 발생된 투명세포연골육종을 보고하고자 한다. Clear cell chondrosarcoma is a rare, low-grade variant of chondrosarcoma that comprises approximately 2% of all chondrosarcomas. This tumor usually involves the epiphysis and epimetaphysis of long bones, especially the proximal part of the femur or humerus, whereas involvement of the scapula is rare. It occurs at any age, but the peak is third to fifth decade, and is rarely seen in the first and second decades of life. Histologically, tumor cells with abundant clear cytoplasm and benign giant cells are usually found. We report on a case of clear cell chondrosarcoma of the scapula in an 8-year-old girl.
천골미골부에 발생한 연골양 척삭종의 세침흡인 세포학적 소견 - 1예 보고 -
김영실,김경미,김진아,이은정,이안희,심상인,Kim, Young-Sill,Kim, Kyoung-Mee,Kim, Jean-A,Lee, Eun-Jung,Lee, An-Hi,Shim, Sang-In 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.2
Chordoma is an uncommon neoplasm that accounts for approximately 1% to 4% of all primary bone neoplasms and thought to originate from remnants of the fetal notochordal elements. It usually occurs in adults and has a predilection for the sacrococcygeal and spheno-occipital areas. Chondroid chordoma, first described by Heffelfinger et al, is a rare variant of chordoma; it contains both chordomatous and chondromatous features, and has a considerably better prognosis than either chordoma or chondrosarcoma. The cytologic findings of fine needle aspiration of sacrococcygeal chondroid chordoma in a 57-year-old man are presented. Aspiration cytology showed many sheets and cords of neoplastic cells in a thick amorphous blue-purple mucinous background. The cells had small too medium sized round nuclei with coarse granular chromatin and abundant eosinophilic or bubbly cytoplasm. Some cells had pleomorphic and hyperchomatic nuclei with prominent nucleoli. Cytologic findings were compared to histologic findings. Histologically, areas of chondroid differentiation were noted which were absent in the cytologic smear. Immunohistochemically, both the chondroid and chordoid areas had an epithelial phenotype and stained for cytokeratin, epithelial membrane antigen and S-100 protein. This is the first case of cytologic findings of chondroid chordoma to our knowledge in literature.