유산소운동과 복합운동이 비만 여고생의 혈중지질과 적혈구 침강속도에 미치는 영향

박근양 ( Keun Yang Park ),김정수 ( Jung Soo Kim ),이미영 ( Mi Young Lee ),오광훈 ( Kwang Hoon Oh ),김일형 ( Il Hyung Kim ),인치석 ( Chi Seok In ),김종원 ( Jong Won Kim ) 한국운동생리학회(구 한국운동과학회) 2011 운동과학 Vol.20 No.4

박근양 · 김정수 · 이미영 · 오광훈 · 김일형 · 인치석 · 김종원. 유산소운동과 복합운동이 비만 여고생의 혈중지질과 적혈구침강속도에 미치는 영향. 운동과학, 제20권, 제4호, 441-448. 2011. 본 연구의 목적은 비만 여고생을 대상으로 12주간의 운동프로그램 유형별적용에 따른 혈중지질과 적혈구침강속도에 미치는 영향을 고찰하는데 그 목적이 있다. 본 연구 대상자는 BMI가 25 kg/㎡이상인 비만 여고생 16명을 대상으로 유산소운동군과 복합운동군에 12주간 참가하게 하였다. 신장(p<.001)과 체질량지수(p<.05)에서 유산소운동군과 복합운동군 모두 통계적으로 유의한 증가를 나타냈다. 체중과 체지방률에서는 유산소운동군과 복합운동군 모두 감소하였으나 통계적으로 유의한 차이가 나타나지 않았다. 유산소운동군에서 HDL-C(p<.05)은 유의하게 증가하였고, LDL-C(p<.01)은 유의하게 감소하였다. 복합운동군은 LDL-C(p<.01)에서만 유의하게 감소하였고, TC, TG에서는 두 운동군 모두 통계적으로 유의한 차이가 나타나지 않았다. 적혈구침강속도에서 유산소운동군(p<.001)과 복합운동군(p<.01) 모두 통계적으로 유의하게 감소하였으나 복합운동군에서 유산소운동군 보다 더 높은 감소율을 나타냈다. 이상의 결과를 살펴볼 때 신체조성과 혈중지질에서 유산소운동군과 복합운동군 모두 유사한 결과를 나타냈으나, 적혈구침강속도에서는 복합운동군이 유산소운동군보다 높은 감소율을 보이는 것으로 나타났다. 이는 신체조성과 혈중지질에서는 유산소 운동과 복합운동 모두 유의한 운동효과를 나타냈지만, 적혈구침강속도에서는 복합운동이 유산소운동 보다 감소율이 높게 나타난 것으로 볼 때 복합운동이 혈관 내 염증상태 변화에 더욱 긍정적인 영향을 미치는 것으로 나타났다. Park, K. Y., Kim, J. S., Lee, M. Y., Oh, K. H., Kim, I. H., In, C. S., Kim, J. W. Effects of Aerobic Exercise and Combined Exercise on Serum Lipid and Erythrocyte Sedimentation Rate in Obese High school Girls. Exercise Science, 20(4), 441-448. 2011. The purpose of this study is to examine the effect of the application of exercise program types on serum lipid and erythrocyte sedimentation rate in obese high school girls for 12 weeks. 16 obese female students with BMI over 25 kg/m2 took part in either the aerobic exercise or combined exercise group. Each group has reached statistical significant increase in height (p<.001) and BMI (p<.05). Both groups have reduced weight and the fat percentage but do not show significant decrease statistically. The aerobic exercise group has increased HDL-C (p<.05), but simultaneously decreased LDL-C (p<.01), which are read as a statistical significant change. The combined exercise group has only presented statistically significant decrease of LDL-C (p<.01). Both TC and TG has presented little statistical significant difference. Both the aerobic and combined exercise groups demonstrated the decrease of erythrocyte sedimentation rate. but the combined exercise group showed steeper decline. both groups have presented positive outcome on the body composition and blood level of HDL-C, LDL-C. When we consider that the positive decrease of erythrocyte sedimentation rate through combined exercise group came out to be higher than the aerobic one, combined exercise group had a more positive impact on the condition of blood inflammation.

월남전 참전 노인에서 한글판 외상후 스트레스 장애 체크리스트-5의 정신측정학적 특성

김종원,정혜경,최진희,소형석,강석훈,김동수,문정윤,김태용,Kim, Jong Won,Chung, Hae Gyung,Choi, Jin Hee,So, Hyung Seok,Kang, Suk-Hoon,Kim, Dong Soo,Moon, Jung Yoon,Kim, Tae Yong 대한불안의학회 2017 대한불안의학회지 Vol.13 No.2

Objective : The PTSD Checklist (PCL) is a self-report screen for posttraumatic stress disorder (PTSD) that can be scored for both diagnostic assessment and symptom severity measurement. The most recent revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) contains a number of changes to the definition of PTSD, and the aim of this study was to assess the psychometric properties of the Korean version of the PCL for the DSM-5 (PCL-5-K). Methods : The participants were 204 Korean veterans of the Vietnam War who completed the PCL-5-K, the Mini Mental Status Examination (MMSE), PTSD module of Structured Clinical Interview for DSM-5, Research Version (SCID5-RV PTSD module), Korean version of Impact of Event Scale-Revised (IES-R-K) and Combat Exposure Scale (CES-K). Results : The PCL-5-K demonstrated good internal consistency (${\alpha}=0.972$) and test-retest reliability (r=0.96); the suggested cut-off score for PTSD diagnosis was ${\geq}37$ with 0.88 sensitivity and 0.96 specificity. The PCL-5-K scale correlated highly with the IES-R-K and CES-K. Factor analysis identified only one factor. Conclusion : Among elderly Korean veterans of the Vietnam War, the PCL-5-K demonstrated similar psychometric qualities to those of both the original PCL and subsequent versions. It is expected that the PCL-5-K will be a useful PTSD screening tool.

신경성 식욕부진 유사 환자 1례에 대한 증례보고

김종원,심재철,김민상,오병열,이지영,조현경,최영,김윤식,설인찬,유병찬,Kim, Jong-Won,Shim, Jae-Chul,Kim, Min-Sang,Oh, Byeong-Yeol,Lee, Ji- Young,Jo, Hyun-Kyung,Chai, Young,Kim, Yoon-Sik,Seol, In-Chan,Yu, Byeong-Chan 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3

Anorexia nervosa is a serious, often chronic, and life-threatening eating disorder defined by a refusal to maintain minimal body weight (within 15% of an individual s normal weight). Other essential features of this disorder include an intense fear of gaining weight, a distorted body image, and amenorrhea(absence of at least three consecutive menstrual cycles when they are otherwise expected to occur). With anorexia nervosa, the nails and hair become brittle, and the skin may become dry and yellow. In addition to depression, hypothermia, lanugo, nausea, vomiting, anxiety and dehydration from sweating can appear. Starvation, weight loss, and related medical complications are quite serious and can result in death. Recently one patient was admitted with anorexia nervosa-like symptoms. The patient is a 18-year-old girl with complaints of weight loss, amenorrhea, anorexia, nausea, vomiting, tremor, and sweating. After treatment through oriental medicine for 2 weeks, most of the symptoms improved. Therefore, this application of oriental medicine is reported with a plea for further investigation.

뇌경색과 뇌출혈의 초기 혈액학적 소견 비교 연구

김종원,심재철,김정근,김정현,백경민,이현의,오병열,조현경,유호룡,김윤식,설인찬,Kim, Jong-Won,Shim, Jae-Chul,Kim, Jeong-Keun,Kim, Jung-Hyun,Baek, Kyung-Min,Lee, Hyun-Eui,Oh, Byeong-Yeol,Jo, Hyun-Kyung,Yoo, Ho-Rhyong,Kim, Yoon-Sik,Seol, 대한중풍순환신경학회 2005 대한중풍.순환신경학회지 Vol.6 No.1

1. Purpose : The purpose of this study was done to compare the sex, past history, hematologic relationship between the Cerebral infarction patients and the Cerebral hemorrhage patients. 2. Methods : We selected the two study groups. The one is 20 Cerebral infarction patients and the other 20 Cerebral hemorrhage patients with confirmed by Brain CT or MRI. We made an investigation into past history. We examined and made a comparative study of CBC, LFT, Na, K, Cl in the both group. 3. Result & Conclusion : In the Cerebral hemorrhage group, there were many patients with Hypertension and Diabetes mellitus than the Cerebral infarction group. In the Cerebral infarction group, there were many patients with abnormal RBC count with no significant. Also, ESR is higher than the other group. Between the Cerebral infarction and the other group, we discovered significant cases with abnormal triglyceride, ALP in the Cerebral infarction group(p<0.05). Abnormal triglyceride is known one of important risk factor of Cerebral infarction, but this study was significant in the Cerebral hemorrhage group. Also, ALP was significant in the Cerebral hemorrhage group. Therefore more extensive research is needed.

두툽상어 matrix metalloproteinase 유전자 cDNA의 클로닝

김종원,조원진,천광호,김규원,김영진,이상준,신혜자,임운기,Kim, Jon Won,Cho, Won Jin,Chun, Kwang Ho,Kim, Kyu-Won,Kim, Yung-Jin,Lee, Sang-Jun,Shin, Hae-Ja,Lim, Woon Ki 한국생명과학회 1998 생명과학회지 Vol.8 No.3

Matrix metalloproteinases(MMP)는 배발생 및 재조직화 등의 정상적인 생체형성과 관절염, 암전이, 치근막염, 골조송증 등의 질병과정에서 collagen이나 proteoglycan과 같은 세포외기질의 구성성분을 분해하는 아연(zinc)효소군이다. 지금까지 다양한 종에서 mmp의 유전자가 클로닝되고 그 기능이 연구되어 왔지만 아직 어류에서는 연구결과가 보고된 바가 없다. 본 연구에서는 한국의 부산연안에 많은 연골어유 투툽상어(Scylliorhinus toraxzame)로부터 RT-PCR(reverse transcriptase dependent polymerase chain reaction)의방법으로 mmp cDNA의 일부를 클로닝하였다. 이것은 염기서열에서 인간, 쥐 및 닭의 membrane type matrix matalloproteinase-3(mt3-mmps)의 염기서열과 74% 동일성을 보이며, 아미노산서열에서는 90%이상의 동일성을 갖고 있다. 또한 MMP에 나타나는 cysteine switch domain, zinc binding domain(HExGH motif), propeptide cleavage site, and RRKR motif등을 가지고 있다. 이러한 결과로부터 본 연구에서 클로닝된 RT-PCR단편은 두툽상어의 mt3-mmp 또는 이와 유사한 유전자의 cDNA이라 믿어진다. Matrix metalloproteinases(MMPs) are a group of zinc enzymes responsible for degradation of the matrix components such as collagen and proteoglycans in normal embryogenesis and remodeling and in many disease processes such as arthritis, cancer, periodontitis, and osteprocess. Genetically distince MMPs have been characterized and their genes have been cloned thus far from a variaty of species but not from fishes. In this stydy, a mmp cDNA was cloned by using RT-PCR(reverse transcriptase dependent polymerase chain reaction) from Scylliorhinus toraxzame(shark), agroup of cartilaginous fish, abundant in the coast of Pusan, Korea. It has 74% base homologue with membrane type matrix matalloproteinase-3 genes(mt3-mmps) from human, rat and chick, and also shows more than 90% residue homologue with them. In addition, it has cysteine switch domain, zinc binding domain(HExGH motif), propeptide cleavage site, and RRKR motif, which are present in MMPs. This result indicates that cDNA fragment cloned here may be mt3-mmp or its analogous gejne cDNA fragment of Scylliorhinus torzame.

Guillain-Barre Syndrome 환자의 한방 치험 1례

김종원,김민상,오병열,유병찬,조현경,김윤식,설인찬,심재철,Kim, Jong-Won,Kim, Min-Sang,Oh, Byeong-Yeol,Yu, Byeong-Chan,Jo, Hyun-Kyung,Kim, Yoon-Sik,Seol, In-Chan,Shim, Jae-Chul 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4

The Guillain-Barre Syndrome(GBS), also called acute inflammatory demyelinating polyneuropathy and Landry's ascending paralysis, is an inflammatory disorder of the peripheral nerves - those outside the brain and spinal cord. It is characterized by the rapid onset of weakness and, often, paralysis of the legs, arms, breathing muscles and face. Finally, it leads to respiratory embarrassment and death. There is often a history of antecedent respiratory or gastrointestinal infection. Recently one patient was admitted with GBS. This patient was a 30 year-old man with quadriparesis, both facial palsy, numbness of hands and feet, and gait disturbance. After two weeks of oriental medicine and acupuncture treatment most symptoms improved. Therefore, this application of oriental medicine is reported with a plea for further investigation.

고열전도성 카본나노튜브-고분자 소재의 응용 기술

김종원,송병갑,김미경,염정현,김해식,Kim, Jong-Won,Song, Byeong-Gap,Kim, Mi-Gyeong,Yeom, Jeong-Hyeon,Kim, Hae-Sik 한국염색가공학회 2011 염색가공 Vol.6 No.-

가족력을 동반한 다발성 치성각화낭종

김종원,김유진,변영남,김종철,김명진,이종호,명훈,Kim, Jong-Won,Kim, Yu-Jin,Pyun, Yung-Nam,Kim, Jong-Chull,Kim, Myung-Jin,Lee, Jong-Ho,Myoung, Hoon 대한악안면성형재건외과학회 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.1

본 교실에서는 가족력을 가지며, 하악에 다발성으로 재발된 치성각화낭종의 증례가 있어 보고하는 바이다. 환자들은 한 가족의 어머니와 두 자녀였으며 그중 어머니와 딸의 경우 낭종적출후 수차례의 재발을 보여 딸은 앞으로도 수술을 예정하고 있다. 낭종이외의 다른 기저세포모반증후군의 증거는 보이지 않았다. 처치로서 어머니와 딸의 경우 낭종적출술을 시행하였고 아들의 경우 낭종적출후 결손부의 크기가 커서 동종골이식을 시행하였다. 현재 어머니와 아들의 경우 재발은 보이지 않고 있으나 향후 지속적인 구강검사를 통해 관리예정이며 유전학적인 검사도 고려하고 있다. A family is presented in which multiple odontogenic keratocysts have been expressed. 3 members of the two generations of family with features of multiple keratocysts, suspected basal cell nevus syndrome have been investigated. The proband, 19-year-old woman and her mother, and her brother suffered from these cysts and two female patients' disease have been recurred multiply though careful treatments. Close attention to the family and routine follow up will alert the clinician to its recurrences and genetic counseling and serial screening for the development of other symptoms, that is malignant skin carcinoma etc.

장상논(臟象論)과 어조주갑류(魚鳥走甲類)에 대한 고찰

김종원,전수형,지규용,김경철,이인선,이광영,김규곤,이용태,Kim, Jong-Won,Jun, Soo-Hyung,Ji, Gyu-Yang,Kim, Kyung-Chul,Lee, In-Sun,Lee, Kwang-Young,Kim, Kyu-Kon,Lee, Yang-Tae 대한동의생리학회 2009 동의생리병리학회지 Vol.23 No.1

After a research on appearance diagnosis and fish, bird, horse, and turtle types, this study concluded as following. Appearance diagnosis is a technique that exams five jang organs by color and shape of eye, nose, mouth, and ear. Four HyungSang types-including fish, bird, horse and turtle types-are evaluated upon the external shape that are created while type of seed changes. Appearance diagnosis focuses on five jang organs. Four HyungSang types focus on external shape, but are eventually related to five jang organs. Thus, two different techniques possess a point in common; five jang organs. The assignment of nose, eye, ear and mouth to the Five elements varies between two techniques. On the viewpoint of formation, appearance diagnosis assigns them to metal-water-wood-fire-earth and movement, and four HyungSang types do to wood-fire-earth-metal-water and constitution. On the viewpoint of body/use and static/dynamic, appearance diagnosis assigns them to metal-water-wood-fire-earth and constitution, and four HyungSang types do to wood-fire-earth-metal-water and movement. If nose, eye, ear, and mouth are assigned by on four HyungSang types, which are based on external shape, the assignment can be utilized in diagnosis. If, however, they are assigned by appearance diagnosis, it can be focus on treatment. Five jang organs and six fu organs are affected by internal conditions because they are located inside of human body, while four HyungSang types are affected by external conditions because it deals with external shape. If a disease occurs in the developed part of the body, it would be difficult to be cured because four HyungSang types depend on external shapes.

뇌졸중(腦卒中)에 대(大)한 한방치료법(韓方治療法) 연구(硏究)(증치의학(證治醫學)과 사상의학(四象醫學)) 및 한방(韓方), 양방(洋方), 양(洋)·한방(韓方) 협진치료(協診治療) 효과(效果)에 관(關)한 연구(硏究)

김종원,김영균,김법영,이인선,이인선,장경전,권정남,이원외,송창원,박동일,Kim, Jong-won,Kim, Young-kyun,Kim, Beob-young,Lee, In-seon,Lee, In-seon,Jang, Kyung-jeon,Gwon, Jeong-Nam,Lee, Won-oe,Song, Chang-won,Park, Dong-il 사상체질의학회 1998 사상체질의학회지 Vol.10 No.2

The Purpose of Study 1. Inspection of clinical application on TCD to CVA 2. Objective Comparement and analysis about treatment effect of Western-Medicine, Korean Medicine, Cooperative consultation of Korean and Western medicice for CVA The Subject of Study We intended for the eighty six patient of CVA who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center from 1997. 8. I to 1998. 7. 31 1. View of CT, MRI : the patient of Cb infarction 2. Attack Time : The patient who coming hospital falling ill within the early one week The method of study 1. Treat four group of Korean medicine, Constitution medicine, Western medicine, cooperative consultation of Korean medicine and Western medicine. 2. Application of TCD Check the result for three times, immediatly after the attack, two months later, four months later 3. Comparative analysis of each treatment effect by clinical symptoms and pathologic examination 4. The Judgement of the patient The Result From 8/1/1997 to 7/31/1998, We have the following result by clinical analysis intended for CVA 86 patients who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center from 1997. 8. 1 to 1998. 7. 31 in 1. Analysis according to Age The first stage of thirties, forties, seventies is heavier than forties, fifties in improvement and Index of improvement of symptom 2. Analysis according to sex We have no special relation in an average of symptom and improvement, Index improvement 3. Analysis according to Family History We have the better result in first stage and improvement, index improvement when no family history. 4. Analysis according to Past History We have no special relation in past history like hypertension, DM, heart problem 5. Analysis devided two group, above group and under group on the basis of the average in first stage of all patient. We have the better result when the first stage is light, that the first score of barthel index and CNS is high. 6. Analysis of the effect of treatment about Korean medical treatment, Western medical treatment, cooperative treatment. In this study, the highest group of rate of treatment at four contrast groups (Korean medicine, Constitution medicine, Western medicine, cooperative treatment according to dyagnosis and range of treatment was the patient group of doing dyagnosis and method of treatment based on constitution medicine theory. This is that of doing demostation, A-Tx, po-herb-medication according to dyagnosis and treat method of constitution of Lee Je-ma In case of left, the case of dyagnosis any disease according to doctor view but, normal in TCDwas 22-beginning of attack, 20- two weeks later, 11 case-four weeks later in case of right, 15-beginning of attack, 12-two weeks later, 9 case four weeks later. So left vessel compares to right vessel is more interference, in fact more than a 1/2 of the patients of MCA disease can't do dyagnosis. In rate of imparement, the state of pacient improved but there isn't the improved case of result in TCD. 7. In TCD dyagnosis, between the case of inconsus the doctor view specially MCA in brain blood vessel is in large numbers and in total 86's patient, impossible case of dyagnosis according to interferiance of temporal is 21 case. 7. Result study about application of Kreaan medical treatment 1) The impossible patient of observation MCA blood vescular for interference temporal bone happened in large numbers. 2) There is the case having difference result to CT,MRI, MRA result. 3) Because individual difference is large, excluding to ananalogy of symptom. This is normal numerical value that has possibility of being checked as abnormal numerical value 4) there are a lot of cases that the speed of normal part is as similarly measured as that of abnormal part. It means that we cannot judge the disease by this measure 5) It is rare that this measure represent degree of improvement in patient's condition of disease. When we observe patient's condition become better, but w