성장장애(成長障碍)에 관(關)한 임상적(臨床的) 연구(硏究)(I)

김장현,Kim Jang-Hyun 대한한방소아과학회 1998 대한한방소아과학회지 Vol.12 No.1

I intended to be helpful to understand significant cause for treated patients comed to Dept of Pediatrics growth clinic in short stature of delayed growth and effect of oriental medical therapy. I studied at first 54 patients(36 men and 18 women) comed to Dept. of Pediatrics growth clinic of Dongguk Pundang Oriental Hospital and investigated characteristics, remidial value and side effect which 20 patients(1l men and 9 women) treated oriental medical therapy in short stature of delayed growth between June 1997 and October 1998. First study resulted the average was 8.37 year(chronological age), 6.96 year(bone age), 15.43 (height percentile by age), 164.2 cm(mid parental height) and the ratio of using the prescription was Bojunggunatang-derivative at first. second study resulted the distribusions of remedial values were improved(55.0%) and no improved(45.0%) patients. remedial values was affected by appetite.

소아설사(小兒泄瀉)에 대한 가감전씨백출산(加減錢氏白朮散)의 임상효능(臨床效能)에 관한 연구(硏究)

김장현,Kim, Jang-Hyun 대한한방소아과학회 2004 대한한방소아과학회지 Vol.18 No.2

Objectives: The objective of this study is to assess the clinical effect of Gagamjeonsibaekchulsan on child diarrhea. Methods: This clinical study was carried out with 42 cases(31male, 11female) of children aged 0 to 14 years old who visited the Department of Pediatrics, Dongguk University Bundang Oriental Hospital and were diagnosed as the diarrhea. Assessments were made with reference to sex, age, the duration of symptoms and physical history. To assess the impact of Gagamjeonsibaekchulsan, the complicated signs, the duration of treatment, the correlation between the use of Gagamjeonsibaekchul- san and the duration of symptom were examined before and after the treatment. Results: There were 31 males and 11 females in the incidence by sex. It showed that males were more than females. The most numerous age group was 0-2(19) followed by 3-7 (11) and 9-12 (12). According to the duration of symptom, 12 children have symptom for 0-7 days, 10 for 8-14 days, 11 for 15-20 days, 4 for 22-28 days and 5 over 28 days. With regard to the physical history of the sample, 5 children had atopic dermatitis, 3 children had enteritis, 3 children had rhinitis, 2 children had tonsillitis, 1 child had otitis media, 1 child had asthma and 1 child had pneumonia. The children also had the complicated signs: 22 children had anorexia, 17 children had abdominal pain, 13 children had vomiting and 8 children had nausea in digestive organ. In addition 11 children had dizziness, 7 children had general weakness, 1 child had enuresis and 1 child had sweat in general symptoms. For the duration of the treatment, 14 children were treated for 7 days, 13 for 8-10 days, 8 for 11-14 days, 3 for 15-21 days, 2 for 22-28 days and 2 for 29-40 days. No distinct relationship between the use of Gagamjeonsibaekchul-san and the duration of the symptom was found. Conclusion: Gagamjeonsibaeichul-san is effective in the treatment of intestine mucous membrane and improves the function of digestive system. It is also an effective short-term treatment for child diarrhea.

소아폐렴(小兒肺炎)의 한의학적(韓醫學的) 연구(硏究)에 대한 고찰(考察) -중의학(中醫學) 문헌(文獻)을 중심(中心)으로-

김장현,권혁란,Kim, Jang-Hyun,Kwon, Hyuk-Ran 대한한방소아과학회 2003 대한한방소아과학회지 Vol.17 No.1

Pneumonia is an acute or recurrent infection of the parenchyma of the lung causing cough, fever, and respiratory distress. Pneumonia was named 'Feiyanchuansou(肺炎喘嗽)' in chinese medicine. This study was progressed for oriental medical treatment for pediatric pneumonia in china. The purpose of this study is current oriental medical approach to pediatric pneumonia In this study, the authors tried to figure out the cause of the pediatric pneumonia and its treatment and came to the conclusion as follows: 1. The study for pediatric pneumonia consists of basic, clinical and experimental study. 2. Basic study consists of etiology and pathogenesis(病因病耭), the rule of treatment(治療原則) and method of treatment(治法). 3. Clinical study consists of symptoms-based treatment(辨證論治), adequate prescription treatment(專病專方), acupuncture(鍼灸治療), and western diagnosis based treatment. 4. The majority of experimental study was pharmacology that consists of antiviral and antibacterial effect, removing heat(淸熱), releasing pulmonary qi(宣肺), dissipating phlegm(化痰).

청소년기(靑少年期)에서 척추체형(脊椎體形)과 자각증(自覺症)과의 임상적(臨床的) 고찰(考察)

김장현,Kim, Jang-Hyun 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.2

Objectives : The purpose of this study was to investigate the spine distortion and self-conscious pain in high school students. Method : Using the phase-shifting moire developed by KAIST(Korea Advanced Institute of Science and Technology) we measured the back surface distortion, and using questionnaire investigation, we investigated the self-conscious pain in 30 high school students(17 boy students and 13 girl students). Results : This study show that low back pain was most cases, and next headache, upper back pain, abdominal pain, neck pain, shoulder pain, leg pain, chest pain and gluteal pain. The ratio of each self-conscious pain was 90.0%, 86.7%, 83.3%, 83.3%, 80.0%, 76.7%, 66.7%, 33.3%, 33.3%, 30.0%. In remainder value of left and right shoulder, above of 3.0 were three students., above 2.0 to bellow 3.0 were 10 students, bellow 2.0 were 17 students. In remainder value of left and right gluteal, above of 2.0 was one students, above 1.0 to bellow 2.0 were 18 students, bellow 1.0 were 10 students. In remainder value of cervical vertical line to left and right axillae, above 4.0 was 1 student, above 3.0 to bellow 2.0 were 2 students, above 2.0 to bellow 3.0 were 3 students, above 1.0 to bellow 2.0 were 16 students, bellow 1.0 were 7 students. In remainder value of gluteal vertical line to left and right axillae, above 6.0 was 1 student, above 5.0 to bellow 6.0 were 7 students, above 4.0 to bellow 5.0 were 3 students, above 3.0 to bellow 4.0 were 2 students, above 2.0 to bellow 3.0 were 5 students, above 1.0 to bellow 2.0 were 7 students, bellow 1.0 were 5 students. In remainder value of cervical vertical line to gluteal vertical line, above 40 was 1 student, above 3.0 to bellow 4.0 were 4 students, above 3.0 to bellow 3.0 were 6 students, above 1.0 to bellow 2.0 were 8 students, bellow 1.0 were 11 students. Conclusion : It is suggested that the significant correlation exist between the spinal distortion and self-conscious pain. And we can find many cases as spinal distortion in high school students also. We have to study further more about juvenile postural distortion and it's prevention.

전산화(電算化) 진단(診斷)의 Database 구축을 위한 소아(小兒) 관형찰색(觀形察色)에 관한 연구(硏究)

김장현,Kim Jang-Hyun 대한한방소아과학회 2001 대한한방소아과학회지 Vol.15 No.1

In oriental medicine, diagnostic method was the four examination(四診) which was composed of inspection(望診), inquiring(問診), listening and smelling(聞診), palpation(切診). Inspection of skin color(望色) indicated the observation of patient's complexion(色診). In oriental medical theory, complexion of face was related to meridians(經絡) and zang-fu(贓腑). The change of complexion was reflected the ups and downs of qi(氣) and blood(血), the relative seriousness of an illness. especially, observation of complexion was essential in children, because of diagnostic difficulty and positive change according to each disease. The purpose of this study was to construct for standard measurement and invent for computerizing diagnostic system which was based on observation of complexion. It was objectively measured complexion using spectrophotometer and chroma meter. Measurement of complexion should make an offer the index of diagnosis.

주의력결핍 과잉행동장애 치료에 대한 문헌적 고찰 -최근 중의 잡지를 중심으로-

김장현,김희은,Kim, Jang-Hyun,Kim, Hee-Eun 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.2

Objective : The aim of this study was to investigate treatment of Attention Deficit Hyperactivity Disorder(ADHD) in current Traditional Chinese Medical Journals. Methods : From January 2000 to December 2005, we searched Traditional Chinese Medical Journals. Results : 21 articles were selected and classified into two large groups, case report and comparison study. Totally 1137 cases, complete cures are 276, significant improvements and some improvement 1028, complete cure rate 24.27%, total improvement rate 90.41%. Conclusion : Oriental medical treatments for ADHD were investigated to be effective in most trials. But there remains a debate about outcome criteria. Further studies are needed. Treatment methods were herbal medicine, acupuncture, auricular acupuncture, family consult.

새로운 인간(人間) 태반(胎盤)유래의 항응고(抗凝固) 단백질(蛋白質) PP27 (annexin Ⅴ형(型) 단백질(蛋白質))의 정제(精製)와 특성(特性)

김장현,Kim Jang-Hyun 대한한방소아과학회 2000 대한한방소아과학회지 Vol.14 No.2

It has long been known that Jahage(紫河車) extracts of Placenta hominis are effective for immunological and vascular diseases in human body and thus, was used a major constituent of traditional oriental medicines. From full-term human placenta, we have purified a new type anticoagulant protein, PP27, using different chromatographic techniques of a phenyl TSK gel 650M column, DEAE, HA and Mono-Q columns. PP27 showed single band on SDS-PAGE with a molecular mass (Mr) of 27 kDa under denaturing conditions and a calibrated Sepharose 4B column chromatography indicated a molecular mass of 23 kDa, indicating that the value is similar to those of other PP4 enzyme reported to date. Isoelectric point of PP27 was p15.2. The protein was found to inhibit the coagulation time in a concentration-dependent manner. PP27 was acted as a vascular anticoagulant of annexin type, inhibits the blood clotting process by binding of the essential lipids in a reaction which is dependent on $Ca2^+$ ions. In the presence of $Ca2^+$ ions, PP27 combines with platelet membranes neutralizing their procoagulant effect. Coagulation triggered by the addition of thromboplastin/ lipid- mixtures is extinguished by PP27.

PubMed를 통한 소아질환에 대한 침술치료 연구의 최신 동향

김장현,박보경,Kim, Jang-Hyun,Park, Bo-Kyoung 대한한방소아과학회 2005 대한한방소아과학회지 Vol.19 No.1

Objectives : We aimed at reviewing the studies related to the treatment of children by acupuncture therapy. Methods : We referred to PubMed by using searching words of acupuncture and the terms of pediatrics, such as child, children, adoiescence, baby, infant, juvenile. 22 journals with 23 paper were searched and reported. Results : 1. We found 23 articles in 22 journais, whose authors were in China, Japan, Germany, Russia, America, Brazil, etc. 2. Clinical trial was the method which these studies had used mostly the pattern of the rest were reviews, case reports of undetermined articles. 3. We analysed articles and found many articles of nocturnal enuresis, postoperative vomiting, etc. 4. The result of clinical studies represented the significant cure rate. 5. The acupuncture instruments on children's diseases were laser acupuncture, acupressure. and herbal skin sticking as well as body acupuncture,. Conclusion : Study of pediatric acupuncture was increasing and effective result was reported.

소아를 주요 대상으로 하는 한의원 웹사이트의 분석 및 고찰

김장현,서영민,Kim, Jang-Hyun,Seo, Young-Min 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.2

Objectives : The Internet is closely related to the live of modern people in the 21st Century. With increasing interest in health and disease of children, the public has access to a growing supply of information on oriental pediatrics clinic through Internet. The purpose of this study is to collect and analyze the Internet web sites concerning oriental pediatrics clinic in Korea, and study the effectiveness of internet toward oriental pediatrics. Methods : We selected 42 web sites by searching for such keyword as child and oriental Medical clinic at korea major web search engine. The sites were evaluated and analyzed on the basis of 24 is under three evaluation criteria such as quality of contents, the easy of use, reliability of web sites. Results: Study results indicated that 34% of web sites were built in 2004, 58% of oriental pediatrics clinic was located in Seoul & Kyunggi and 84% of them was connected network medical system. About health information was supplied in oriental pediatrics clinic web sites, the growth was high frequent information, 50% of web sites supplied high quality information and 19% of them was supplied high diversity information. Conclusions: It is necessary to control system as information certification system in the area of oriental pediatrics clinic web sites.

뇌성마비(腦性痲痺)의 한의학적(韓醫學的) 접근(接近)에 관한 최신(最新) 동향(動向)

김장현,한윤정,Kim, Jang-Hyun,Han, Yun-Jeong 대한한방소아과학회 2003 대한한방소아과학회지 Vol.17 No.2

Back ground : Cerebral palsy(CP) is a static encephalopathy caused by an insult to the brain during the prenatal, perinatal, or postnatal period (ie, up to 2 years). CP can lead to global dysfunction but always includes motor problems Objective : The purpose of this study is to investigate the current tendency of oriental approach to the CP and promote oriental treatment of CP in Korea Method : Investigation of current literature and clinical paper in Korea and Chinese Result and Conclusion : 1) CP fall under the category of wu-chi(five kinds of retardations : 五遲), wu-ruan(five kinds of flaccidity : 五軟), wu-ying(five kinds of Stiffness : 五硬) in oriental medicine and correspond to naoxing-tanhuan in current chinese medicine. 2) CP is mainly caused by weakness of the liver and kidney(肝腎不足), weakness of the spleen and stomach(脾胃虛弱), and the method of treatment is tonify the liver and kidney(補益肝腎), tonify the spleen and replenish qi(補脾益氣), but yu-chi(the faculty of speech : 語遲) is caused by deficiency of the heart(心虛) so that treated with method of invigorating the heart and nourishing blood(補心養血). Recently blood stagnancy the stagnation of qi(氣滯血瘀) is considered as the cause of CP, promoting qi circulation to invigorate blood(行氣活血) is mentioned the treatment of method. 3) In addtion to a herbal medication and acupuncture, the various treatments of scalp acupuncture(頭鍼), acupoint injection(穴位注射), catgut embedding therapy(埋鍼) etc. had been applicated to CP and for the objective evaluation of remedial value, TCD, EEG, BMD have been used.