화영지통탕(和營止痛湯)의 혈관신생억제효과(血管新生抑制效果)에 관한 실험적(實驗的) 연구(硏究)

김인석,박준혁,강희,김성훈,유영법,심범상,최승훈,안규석,Kim, In-Seok,Park, Joon-Hyuck,Kang, Hee,Kim, Sung-Hoon,Yu, Young-Beob,Shim, Bum-Sang,Choi, Seung-Hoon,Ahn, Koo-Seok 대한암한의학회 2001 大韓癌韓醫學會誌 Vol.7 No.1

The purpose of this study is to prove the angiogenesis effects of WhaYoungJiTongTang (hereinafter referred to as the 'WYJTT'). For the study, by utilizing liver cancer cell line; SK-HEP-1, lung cancer cell line: A549, stomach cancer cell line: AGS and bovine capillary endothelial cell: BCE, the effects of the WYJTT on toxicity and proliferation ability of cells and the effects on anti-angiogenesis of bovine capillary endothelial cell and of mice's aorta were studied. 1. Cell viability assay In comparison with the control group, when $100{\mu}g/ml$ of WYJTT was injected, the viability was reduced in SK-Hep-1, $400{\mu}g/ml$ in A549 and $200{\mu}g/ml$ in AGS. 2. Cell proliferation assay In comparison with the control group, when $600{\mu}g/ml$ of WYITT was injected, DNA synthesis was reduced to 35.1% in the SK-Hep-1, 56.0% in A549, and 25.8% in BCE (bovine capillary endothelial cell); and when $400{\mu}g/ml$ was injected, DNA synthesis was reduced to 12.1 in AGS. 3. Tube formation assay In the event that BCE is injected with WYJTT in each of its content gradient, the anti-angiogenesis was effective in amounts of $400{\mu}g/ml$ with 6 hours of the treatment. 4. Aortic ring assay In comparison with the control group, the angiogenesis was restricted to the remarkable degree in amount of $200{\mu}g/ml$: 10% in $400{\mu}g/ml$; and fully inhibited in each of $800{\mu}g/ml$ and $1600{\mu}g/ml$. As a result of the experiments mentioned above, WYJTT showed its anti-angiogenesis effects against cancer cell line.

영어말하기 교육과정 현황 및 운영에 관한 실태연구

김인석(Kim In Seok),김봉규(Kim Bong Gyu) 한국영어학학회 2017 영어학연구 Vol.23 No.1

The purpose of this study is to report on the current status for the English speaking curriculum and instruction in the Korean middle schools through the nation-wide online survey conducted to students, parents, and teachers. This study attempts to provide an in-depth analysis of schools’ reponses to the 9 survey question items on the English speaking curriculum in schools and those of students(1,372), teachers(1,584) and parents(1,294) on the English speaking instruction for improving its effectiveness. The results showed that various types of English programs were designed and implemented in order to enhance students’ motivations for learning English as a foreign language such as after-school programs, differentiated classroom instruction, multimedia based language teaching, and so on. It was revealed that a majority of all three groups favorably responded to items that asked their satisfaction about the school’s English speaking instruction. A number of methodological and environmental improvements affecting English language learning were called for, which ranged from improving teachers’ English teaching methodology, reducing the class size, developing the multifarious materials such as workbooks, digital contents for students and teachers, and to using interesting school text books. Based on the results of the study, pedagogical implications for improving the English speaking programs in school classrooms are suggested.

철근콘크리트와 강을 합성한 복합 단면보의 구조거동평가

김인석,김학수,Kim, In Seok,Kim, Hak Soo 한국강구조학회 2008 韓國鋼構造學會 論文集 Vol.20 No.5

최근 장대 건설 구조물에 사용이 증가되고 있는 합성형 구조물에서 나타나고 있는 예기치 못한 일부 균열 현상의 구조적 원인을 분석하기 위하여, 강재복부의 수직보강재, stud 및 dowel bar의 유무, 전단철근의 간격과 콘크리트 강도 등을 실험변수로 하여 4점 재하 휨시험을 통해 강재와 철근콘크리트간의 구조적 합성거동 효과를 분석 하였다. 실험결과, 수직보강재는 강재의 국부좌굴 방지와 파괴시 강재와 콘크리트의 부착파괴를 방지하여 구조적 합성거동에 따른 단면내력(파괴하중)의 증진에 효과적인 것으로 나타났으나, 추가적으로 설치한 stud 및 dowel bar, 콘크리트의 강도와 전단철근량 등은 합성보의 휨거동에 큰 영향을 주지 않는 것으로 나타났다. The composite structures of steel and reinforced concrete, which have been widely used in large-scale concrete structures, werestudied to investigate the cause of unexpected cracks and to verify the composite actions between the two materials. Vertical stiffeners between flanges, studs and dowel bars, stirrups, and concrete strength were chosen as experimental variables in afour-point loading test. The results showed that the vertical stiffener prevented not only the local web buckling, but also bond failures between steel and concrete. It increased the flexural resistance (fracture loads) due to the composite action of two materials, compared withthose of any experimental variable. However, the composite behavior of steel reinforced concrete beam was not affected seriously by additional studs, dowel bars, stirrups, and concrete strength.

단국대학교 천안캠퍼스 제3과학관

김인석,Kim, In-Seok 대한건축사협회 2004 建築士 Vol.2004 No.9

건축사 보수의 허와 실

김인석,Kim, In-Seok 대한건축사협회 1979 建築士 Vol.1979 No.6

회원작품 - 대한교원공제회 광주회관

김인석,Kim, In-Seok 대한건축사협회 1996 建築士 Vol.1996 No.11

자매에서 발생하는 Leigh 병 (아급성 괴사성 뇌척수병증)

김준현(Jun Hyeon Kim),김인정(In Jeong Kim),김인석(In Seok Kim),윤원상(Won Sang Yoon),김은영(Eun Young Kim),김성호(Sung Ho Kim),우영종(Young Jong Woo) 대한소아신경학회 1997 대한소아신경학회지 Vol.5 No.1

In two female siblings, growth and developmental retardation, poor sucking, anorexia, floppiness and respiratory difficulty developed around 2 and 4 monthes of age in each, and the respiratory symptoms rapidly aggravated to comatose states and finally into death one month later, On admission at emergency room, severe acidosis and high lactate and pyruvate levels in serum and cerebrospinal fluid were revealed in one. Brain computed tomography and magnetic resonance imaging revealed identical bilateral involvement of putamen in both of the sibs, which made the diagnosis of Leigh disease(subacute necrotizing encephalomyelopathy) possible. There is also a family history of early death in infancy period: an elder sister and a brother of mother died with unknown cause at their 5 and 10 months of age. Mitochondrial enzyme functions could not be assayed.

야전운용자료를 활용한 항공무기체계의 RAM 목표값 비교분석

김인석(In Seok Kim),정원(Won Jung) 한국신뢰성학회 2015 신뢰성응용연구 Vol.15 No.4

Purpose : The purpose of this study is to compare the RAM (reliability, availability and maintainability) value in the acquisition phase with operational period for air weapon systems. The objective is to determine if the value of RAM is sufficient in the field, and look for any difference from the target value to some extent. Methods : For a case study, the ○○ training aircraft is selected. Data from the two acquisition sources are utilized. One is the operational data in domestic aircraft through research and development, and the other is the data from imported aircraft. The two different sources were collected independently and distinctly. Results : According to the analysis, the domestic aircraft shows high deviation in RAM value compare to the imported systems. This is due to the effort of continuous reliability improvement. In the aspect of maintainability, the result shows a slight deviation, and the availability meets the requirement. Conclusion : The results of this study can be used in finding a way that can be effectively applied to the sustainability in the weapon system. If the RAM performance is significantly lower than the target value, then it is necessary to improve the design activities so that they can achieve the RAM target value.

인공지능형 대화형 챗봇 현황과 영어교육용 챗봇 개발 방안

김인석 ( In-seok Kim ),김봉규 ( Bong-gyu Kim ) 21세기영어영문학회 2020 영어영문학21 Vol.33 No.2

The purpose of this study is to explore the current state of interactive AI chatbot development, focusing on ICT based new technology trends, and suggest ways of applying this chatbot technology to develop English education chatbots. First, this study explains the major principles of AI-based interactive chatbot development in recent years. Second, it also presents the basic structure of the AI-based chatbot system and its application of intelligent learning processes in English language education. In addition, with the development of future technologies, interactive AI chatbots can be expected to be used in many fields such as personal assistant service, interactive commerce, and the entertainment industry. Especially, the chatbot system is expected to enhance learners’ foreign language competence and motivation in language education settings.

비디오 컨퍼런싱을 통한 중학교 정규수업 및 방과 후 영어 수업에 관한 연구

김인석 ( In Seok Kim ),김봉규 ( Bong Gyu Kim ) 한국중등영어교육학회 2012 중등영어교육 Vol.5 No.2

The purpose of this research is to find out Korean middle school students’ attitudes toward English learning via videoconferencing co-taught by native teachers of English and Korean English teachers. It was carried out from July, 2011 to February, 2012 with 200 middle school students from 4 English schools designated by the MEST and 11,354 students from 113 other middle schools. A questionnaire was given to all these students to find out their attitudes toward the videoconferencing English classes. Data analyses showed that students were satisfied with English lessons via videoconferencing to a large extent. In addition, students showed positive attitudes towards the native English teachers`` model of classes as well as the co-teaching model. Based on the questionnaire from the teachers who co-taught with their foreign counterparts, the research illustrates a number of useful practices by schools who made the videoconferencing Englishlanguage teaching more effective. The research has suggested such features as technical difficulties and collaboration between Korean and foreign English teachers for improvement in order to provide well designed videoconferencing English classes in Korean middle schools.