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강윤미 ( Yun Mi Kang ),김경숙 ( Kyung Sook Kim ),이주영 ( Ju Young Lee ),이정화 ( Jung Hwa Lee ),김이슬 ( E Sle Kim ),이봉 ( Bong Lee ),박영환 ( Young Hwan Park ),고재훈 ( Jae Hoon Ko ),강길선 ( Gil Son Khang ),이해방 ( Hai Bang 한국조직공학과 재생의학회 2008 조직공학과 재생의학 Vol.5 No.4
Various gene transfer play important roles in the development of the controlled release of nucleic acid. In this review, we describe a relatively new approach to the immobilization and release of DNA from surfaces and detailed overview of the state of the art. First, methods based on the layer-by-layer assembly of thin multilayered films will be discussed. The applications of layer-by-layer assembly to the fabrication of DNA-containing surfaces will be then presented. We believe this approach can contribute potential method for spatial and/or temporal control over the delivery of DNA.