마찰접합 된 A6063 합금의 미세조직과 기계적 특성 평가

김은혜,조형환,송국현,Kim, Eun-Hye,Cho, Hyung-Hwan,Song, Kuk-Hyun 한국재료학회 2017 한국재료학회지 Vol.27 No.5

This study was carried out to evaluate the developed microstructures and mechanical properties of friction welded A6063 alloy. For this work, specimens were prepared at a size of 12 mm ${\O}{\times}80mm$, and friction welding was carried out at a rotation speed of 2,000 RPM, friction pressure of $12kgf/cm^2$ and upset pressure of $25kgf/cm^2$. To perform an analysis of the grain boundary characteristic distributions, such as the grain size, orientation and misorientation angle distributions, the electron back-scattering diffraction method was used. In addition, in order to identify the dispersed intermetallic compounds of the base and welded materials, transmission electron microscopy was used. The experimental results found that the application of friction welding on A6063 led to significant grain refinement of the welded zone relative to that of the base material. Besides this, intermetallic compounds such as AlMnSi and $Al_2Cu$ were found to be dispersed with more refined size relative to that of the base material. This formation retains the mechanical properties of the welds, which results in the fracture aspect at the base material zone. Therefore, based on the developed microstructures and mechanical properties, the application of friction welding on A6063 could be used to obtain a sound weld zone.

불로 구기 부위별 자유라디칼 소거효과에 관한 연구

김은혜,김현위,김수동,이보희,이철호,고경희,Kim, Eun-Hae,Kim, Hyeon-Wee,Kim, Su-Dong,Lee, Bo-Hee,Lee, Cherl-Ho,Koh, Kyung-Hee 한국식품과학회 2005 한국식품과학회지 Vol.37 No.1

Free radical-scavenging activities of Korean Bulro Kugi (Lycium chinense Mill) fruit, leaf, and root were evaluated. Total phenolic contents of fruit, leaf, and root were $1,078.4{\pm}61.0$, $939.9{\pm}19.8$, and $3,792.2{\pm}106.6mg/L$, and their flavonoids were $396.7{\pm}15.2$, $1,952.9{\pm}21.3$, and $425.3{\pm}13.5mg/L$, respectively (p<0.001). HPLC revealed main polyphenolic compounds in fruit were p-coumaric and syringic acids in fruit, p-coumaric, syringic, and procatechuic acids in leaf, and p-coumaric, syringic, caffeic, and procatechuic acids in root. Highest radical-scavenging activities of superoxide anion and hydroxyl were found in leaf and root, respectively (p<0.001). 불로 구기의 부위별 열매, 잎, 뿌리의 라디칼 소거 효과를 연구하였다 총 페놀함량은 불로 구기열매, 잎, 뿌리에서 각각 $1,078.4{\pm}61.0mg/L$, $939.9{\pm}19.8mg/L$, and $3,792.2{\pm}106.6mg/L$의 함량은 나타내었으며 총 플라보노이드 함량은 구기열매, 잎, 뿌리에서 각각 $396.7{\pm}15.2$, $1,952.9{\pm}21.3$, and $425.3{\pm}13.5mg/L$의 함량을 나타내었다(p<0.001) 열매에서는 p-coumaric acid 0.018 mg/100g, syringic acid 0.006 mg/100g이 검출되었고, 잎에서는 p-coumaric acid 0.068 mg/100g, syringic acid 0.064 mg/100 mg, procatechuic acid 0.05 mg/100 mg이 검출되었다. 뿌리에는 p-coumaric acid 0.178 mg/100 mg, syringic acid 0.046 mg/100 mg, caffeic acid 0.043 mg/100 g과 procatechuic acid 0.022 mg/100 mg이 검출되었다. 불로구기의 주요 폴리페놀 성분들은 p-coumaric acid과 syringic acid이었으며 잎에서는 열매에서 확인되지 않은 caffeic acid가 뿌리에서는 caffeic acid procatechuic acid 성분이 함유되어 있었다. 총 폴리페놀 함량은 뿌리 0.29 mg/100 g, 잎 0.18 mg/100 g, 열매 0.03 mg/100 g의 순으로 뿌리에 가장 많이 함유되어 있는 것으로 나타났다. 불로 구기의 부위별 superoxide anion radical 소거능력은 잎, 뿌리, 구기열매가 각각 $60{\pm}0.1%$, $47.7{\pm}0.1%$, $21.6{\pm}0.1%$의 순으로 잎에서 가 장 높은 소거효과가 나타났으며, hydroxyl radical 소거능력은 superoxide anion radical 소거능력에 비해 효과가 약하나 뿌리에서 $34.6{\pm}0.1%$로 높은 소거효과를 나타내었다(p<0.001).

겹치기 마찰교반접합 된 Al6061/HT590 합금의 기계적 특성 평가

김은혜,이광진,송국현,Kim, Eun-Hye,Lee, Kwang-Jin,Song, Kuk-Hyun 대한용접접합학회 2015 대한용접·접합학회지 Vol.33 No.2

This study was carried out to evaluate mechanical properties of the jointed Al6061/HT590 alloys by friction stir welding (FSW). FSW was conducted under the conditions with tool rotating speed of 500 RPM and traveling speed of 300 mm/min., where Ar gas was introduced to prevent the materials from corrosion during the welding process. Electron back-scattering diffraction (EBSD) was used to characterize microstructures such as grain size, misorientation angle and crystal orientation. Evolution of intermetallic compounds in Al6061 during the process were examined in terms of morphology, size and aspect ratio at three distinct zones Al base material, heat affected zone and stir zone, where transmission electron microscope (TEM) was used. It was revealed that FSW gave rise to refinement of grains as well as growth of intermetallic compounds in Al6061. The morphological changes of intermetallic compounds exerted an influence on mechanical properties, resulting in occurrence of fracture in the part of the base material instead of the jointed parts (heat affected zone and stir zone). This study systematically evaluated the microstructural evolutions during the FSW for joining Al6061 with HT590 and their effect on mechanical properties.

전이 췌장암 환자의 Gemcitabine과 방암탕 가감방 및 건칠단 병용투여 치험 1례

김은혜,윤성수,이지영,윤성우,Kim, Eun Hye,Yoon, Sung Soo,Lee, Jee Young,Yoon, Seong Woo 대한암한의학회 2018 大韓癌韓醫學會誌 Vol.23 No.2

Objectives: This study was aimed to report a patient with metastatic pancreatic cancer treated with modified Bangam-tang and Gunchil-dan in conjunction with gemcitabine. There were better survival-related outcomes compared to gemcitabine alone. Methods: The patient with metastatic pancreatic cancer received gemcitabine as palliative chemotherapy since June 2016 concurrent with modified Bangam-tang and Gunchil-dan since October 2016 to October 2017. To evaluate the effect of treatment, tumor markers (carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA)), Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1, and overall survival were checked. Adverse events were evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) version 5.0. Results: After 12 months with the combination treatment, levels of CA19-9 were decreased from 8747 to 265.7 ng/ml and CEA from 42.2 to 6.5 U/ml. Clinical partial response state was shown until May 2, 2017 and stable disease state was maintained from August 4, 2017. In March 2018, the patient got an operation including pancreatectomy and diagnosed with no evidence of disease state in September, 2018. In conclusion, it showed the overall survival of 29 months from June, 2016 to November, 2018. Serious adverse events were not identified. Conclusions: This study suggested that combined treatment with modified Bangam-tang and Gunchil-dan may show better outcome in patient with metastatic pancreatic cancer than gemcitabine alone.

항암화학요법 유발 말초신경병증에 대한 한약의 치료 효과: 체계적 문헌고찰 및 메타 분석

김은혜,윤지현,이지영,윤성우,Kim, Eun Hye,Yoon, Jee-hyun,Lee, Jee Young,Yoon, Seong Woo 대한암한의학회 2020 大韓癌韓醫學會誌 Vol.25 No.2

Objective: This study was aimed to report the therapeutic effects of herbal medicine on chemotherapy-induced peripheral neuropathy (CIPN). Methods: The prior studies were searched from the databases included PubMed, Cochrane Library, EMBASE, CNKi, CiNii, KISS, NDSL, KMBASE, and OASIS until September 2020. The main search keywords were chemotherapy, peripheral neuropathy, and herbal medicine, and only randomized controlled trials that analyzed the therapeutic efficacy of herbal medicine were included. The Cochrane's Risk of Bias was used for assessment of the risk of bias and the Review Manager 5.3 program was used for meta-analysis. Meta-analyses were grouped by the administration routes of herbal medicines (oral administration or topical use). Results: Nine studies with a total of 563 participants were included. Compared with usual care, the effective rate was higher in oral administrated herbal medicine (RR 1.67, 95% CI 1.25 to 2.23; p<0.001, I2=31%). In addition, topical herbal medicine showed an significantly higher effective rate than placebo (RR 2.20, 95% CI 1.52 to 3.18; p<0.001, I2=0%) and usual care (RR 2.24, 95% CI 1.74 to 2.89; p<0.001, I2=66%). There was no severe adverse effect in all participants. Conclusions: Herbal medicine appears to improve neuropathy caused by chemotherapy in cancer patients more than conventional therapy of CIPN. However, as there is heterogeneity between the included studies and a lack of blinding, further well-designed researches are more needed.

청소년이 지각한 사회적 자본이 유데모니아에 미치는 영향: 인권의식을 매개로

김은혜,손한결,Kim, Eun Hye,Sohn, Han Gyeol 한국학교ㆍ지역보건교육학회 2021 한국학교지역보건교육학회지 Vol.22 No.3

Objectives: The purpose of this study was to examine the mediating effect of human rights consciousness on the relationship between social capital and eudaimonia perceived by adolescents. Methods: The participants of this study were 9,021 adolescents, with data taken from the 6^th year(2018) panel survey. All variables were evaluated by self-report of adolescents. The data were analyzed by SPSS 21.0 and AMOS 21.0. Results: First, social capital perceived by adolescents had a direct effect on eudaimonia. Second, social capital perceived by adolescents had an indirect effect on the eudaimonia through human rights consciousness. Conclusions: This study highlighted that human rights consciousness was identified as important mediator in the relationship between capital perceived by adolescents and eudaimonia. These results can be used as an important contribution to further research and educational practices for promoting the eudaimonia in adolescents.

파클리탁셀을 함유한 지질나노입자의 제조와 인공 소화액에서의 안정성 평가

김은혜 ( Eun Hye Kim ),이정은 ( Jung Eun Lee ),임덕휘 ( Deok Hwi Lim ),정석현 ( Suk Hyun Jung ),성하수 ( Ha Soo Seong ),박은석 ( Eun Seok Park ),신병철 ( Byung Cheol Shin ) 한국약제학회 2008 Journal of Pharmaceutical Investigation Vol.38 No.2

코로나 19 상황에서 성인 발달장애인의 미래설계 지원프로그램을 통한 사회적 관계망 변화

김은혜(Kim Eun-hye),한정은(Han Jeong-Eun),정은주(Jung Eun-Jue) 학습자중심교과교육학회 2021 학습자중심교과교육연구 Vol.21 No.20

목적 본 연구의 목적은 코로나 19 상황에서 진행된 성인 발달장애인의 미래설계 지원프로그램을 통한 참여자들의 사회적 관계망 변화를 파악하는데 있다. 방법 이를 위하여 2020년 6월부터 7개월간 프로그램을 진행하였으며, 20대에서 50대까지 성인 발달장애인 12명이 최종 사회적 관계망 연구에 참여하였다. 연구는 사회적 관계망 척도를 사용한 양적연구와 개별인터뷰 및 관찰기록지를 활용한 질적연구의 혼합연구방법론을 사용하여 진행되었다. 결과 양적연구 결과, 프로그램에 참여한 성인 발달장애인의 사회적 관계망은 정서적 지지, 정보적 지지, 친밀도, 접촉빈도의 부분에서 증가하였고, 물질적 지지는 감소한 것으로 나타났다. 또한 연령별(35세 기준)로 청년 그룹과 중장년 그룹의 사회적 관계망 변화를 살펴본 결과, 중장년 그룹이 청년 그룹에 비해 사회적 관계망이 더욱 뚜렷하게 변화된 것을 알 수 있었다. 질적연구 결과, 프로그램에 참여한 성인 발달장애인의 사회적 관계망 변화로 ‘다양한 경험을 통한 사회적 관계망의 긍정적 변화’와 ‘사회 환경 변화에 따른 사회적 관계망 구축 및 지속적인 지원 필요’의 상위주제가 도출되었다. 결론 성인 발달장애인의 미래설계 지원프로그램이 사회적 관계망의 변화에 효과적인 것으로 나타나, 향후 이들에 대한 평생과정설계로서 체계적이고 지속적인 지원정책이 마련되어야 함을 제안하였다. Objectives The purpose of this study is to identify the change in the social network of future design support program participants who are adults with developmental disabilities, which took place during COVID-19 situation. Methods The program went on for 7 months from June 2020, and 12 adults with developmental disabilities in their 20s to 50s participated in the final study of social network. The study was conducted by both quantitative method using social network criteria and qualitative method using individual interview and observation records Results The quantitative research method showed that the social network of adults with developmental disabilities who participated in the program increased in the parts of emotional support, informational support, closeness and contact frequency whereas material support decreased. Additionally, when the change in social network of youth and middle age group was studied (age 35 as the dividing point), middle age group showed more evident change in their social network compared to the youth group. The qualitative research showed that the change in social network of participants who are adults with developmental disabilities led to higher topic of ‘positive change in social network through various experiences’ and ‘need for continuous support and construction of social network according to changes in the society’. Conclusions It was shown that future design support program was effective in change of social network of adults with developmental disabilities, and thus it can be proposed that systematic and continuous support policy as lifelong course design should be arranged.

무용전공자를 위한 고등교육 진로개입 실태분석

김은혜 ( Kim Eun Hye ),남진희 ( Nam Jin Hee ),박재근 ( Park Jae Keun ) 한국무용과학회 2018 한국무용과학회지 Vol.35 No.3

대학 무용전공자의 다각화된 진로개발을 위해서는 직업지도, 진로교육, 진로상담을 포함하는 진로개입(Career Intervention)을 교육현장에서 체계적으로 수행하는 것이 필수적이다. 이에 본 연구의 목적은 대학 무용전공자를 위한 진로개입 실태를 확인하고 발전 방향을 제시하는 것이다. 이를 위하여 최근 무용전공 졸업생들의 취업 실태를 분석하였으며, 무용학과 내 진로·취업 관련 교과목의 현황과 특성을 분석하였다. 이 연구는 현재 무용학과 또는 무용 전공이 개설된 4년제 대학 36개교를 연구의 대상으로 조사하였고, 이 중 30개교(83%)를 대상으로 진로개입에 관한 설문조사를 실시하였다. 분석결과를 바탕으로 도출된 결론은 다음과 같다. 대학 무용전공자를 위한 진로개입은 외형적으로 확대된 모습을 보이고 있으나 체계적인 진로개입을 위한 접근 방안은 미비한 것으로 나타났다. 먼저, 무용전공자를 위한 직업지도를 충분히 지원할 수 있는 정보나 프로그램이 부족한 것으로 나타났다. 다음으로, 대학 무용전공자를 위한 진로교육은 실천적인 형태로 학생들의 진로의사결정에 실재적이고 직접적인 기여를 하기 보다는 형식적인 절차에 의해 이루어지고 있는 것으로 나타났다. 마지막으로 대학무용 전공자를 위한 진로상담은 직업지도와 진로교육에 비해 비교적 잘 이루어지고 있는 것으로 나타났다. 이를 토대로 이 연구는 대학 무용전공자를 위한 진로개입 발전 방안으로 무용직업군 직업표준체계 및 진로흥미검사를 위한 도구, 진로교육을 위한 체계적인 콘텐츠와 진로상담 가이드라인의 개발이 절실하다는 것을 제안하였다. The purpose of this study is to examine the actual status of career intervention for university dance majors and present a direction for development. The employment rate of dance major graduates was analyzed through literature analysis, and the characteristics of the curriculum subjects in dance departments related to career path and employment were analyzed. In addition, a survey on career intervention was conducted with administrative professionals working in university dance departments. Findings drawn from the analysis of the current state of career intervention for dance majors are as follows: Career intervention for dance majors appears to have expanded, but results showed that approaches to systematic career intervention are still lacking. First, there were not enough information or programs that fully support Vocational guidance for dance majors. Next, career education for dance majors were being carried out merely as formality. Finally, career counseling for dance majors were being conducted at a better level compared to career guidance and career education. Based on these findings, this study suggested career intervention development measures for dance majors.

말하기 평가에 구현된 한국어 초급 학습자의 의사소통 전략 양상

김은혜 ( Eun Hye Kim ) 국어교육학회 2011 國語敎育學硏究 Vol.40 No.-

본고는 한국어 초급 학습자의 말하기 평가에서 의사소통 전략이 구체적으로 어떤 양상을 보이는가를 논의하기 위해 의사소통 전략이 무엇이며 의사소통 전략은 의사소통 능력과 어떤 관계를 맺고 있으며 그 유형은 무엇인지에 대해 살펴보았다. 의사소통 과정에 관여하는 여러 요인을 의사소통 모형으로 만들어 보고 화자의 전달 능력과 청자의 이해 능력에 초점을 두어 의사소통 전략의 평가 요소를 추출하였다. 의사소통 전략이 실제 평가에 구현되려면 평가 목적, 대상, 평가 내용에 따라 선별될 필요가 있음에 착안하여 실제 평가를 인터뷰, 대화, 발표라는 각기 다른 말하기 표현 양식으로 구상하였고 인터뷰와 대화, 발표의 각기 다른 양식에서 사용하는 전략에 차이가 있음을 보였다. The purpose of this study is to investigate the aspects of communication strategies in speaking evaluation for beginner level of Korean learners. For this purpose, the definition of communication strategies, the relations between communicative competence and communication strategies, and types of communication strategies were discussed. A communication model and the evaluation criteria of communication strategies were extracted through this process, focusing on speaker`s productive abilities and listener`s receptive abilities. This study included various speaking evaluation tasks such as interviews, dialogues, and presentations because communication strategies should be served differently according to the purpose, subjects, and contents of evaluation. The research showed learners practised different communication strategies according to the context.