B형간염바이러스 및 C형간염바이러스의 표식자 양성율과 원발성 간세포 암의 연관성에 대한 환자-대조군 연구

안형식,김민호,김영식,김정순,Ahn, Hyeong-Sik,Kim, Min-Ho,Kim, Young-Sick,Kim, Joung-Soon 대한예방의학회 1997 예방의학회지 Vol.30 No.1

To investigate the association between hepatocellular carcinema(HCC) and infection of hepatitis B virus(HBV) and hepatitis C virus(HCV) in an HBV endemic area, a case-control study of 254 patients with HCC and of 1,270 age and sex matched health control subjects was done. Among the 254 HCC patients 166(65.4%) were positive for hepatitis B surface antigen(HBsAg), 49(19.3%) were positive for HCV antibody (anti-HCV Ab). The crude odd ratio of patients with HBsAg was 36.1(95% CI :22.4-58.2) and with anti-HCV Ab was 9.0(95% CI :5.5-14.6). In an analysis, which HBsAg(-), HBcAb(-), anti-HCV Ab(-) group was chosen as referent group, odd ratio of HBsAg(+) group was 14.4(95% CI: 7.2-28.9) and of anti- HCV Ab(+) was 10.7(95% CI: 2.9-40.0). odd ratio of anti-HCV Ab(+), HBsAg(+) group and anti-HCV Ab(+), HBsAg(-), HbcAb(+) group for HCC were elevated to 27.3(95% CI : 9.0-82.9), 15.9(95% CI:7.1-35.8) respectly, The odd ratio of anti-HCV Ab(-), HBsAg(-), HBcAb(+) group was 2.4(95% CI : 1.1-5.0). These result suggested that HBV and HCV were associated with HCC. In HBV endemic area patients with HBcAb alone should be considered risk group for HCC.

아스팔트 개질제 변경에 의한 소음저감 연구

김병준(Joon-Byeong Kim),김영식(Young-Sik Kim),김기선(Gi-Sun Kim),남인식(In-Sick Nam),최원식(Won-Sik Choi) 한국산학기술학회 2014 한국산학기술학회 학술대회 Vol.- No.-

본 연구는 도로교통소음을 줄이기 위하여 RSBS(Radial type SBS) 개질제를 이용하여 공극률과 내 구성을 동시에 확보하고자 하였다. RSBS 개질제는 Radial type의 SBS를 주원료로 개발되어 기존의 Linear type의 SBS보다는 한 단계 진보된 재료로 알려져 있다. RSBS는 Styrene과 Butadiene이 사방 으로 연결되어 아스팔트와 용해시 골재간의 결합력, 피복두께, 내구성 등 품질을 향상시켜 저소음∙배 수성 아스팔트의 가장 큰 문제점인 탈리를 막을 수 있으며, Linear type의 SBS를 사용한 포장체에서 구현할 수 없었던 22%이상의 공극률이 가능한 장점이 있다. 소음도의 경우 5분등가소음도, 근접음의 세기측정, 포장면의 통과소음도등 여러 방법으로 소음측정을 실시하여 확인결과, RSBS저소음 복층포 장과 일반포장의 소음도차는 평균 9.7dB(A), RSBS저소음 복층포장과 저소음 단층포장의 소음도차는 평균 3.2dB(A)임을 확인하였다. 안정도는 기존 소재 제품에 비해 안정성이 우수한 수준으로 조사되어 소음 및 내구성, 도시미관 등 기존 도로 포장제의 단점을 줄일 수 있을 것이다.

고온에서 천연산 망간광석과 황화수소의 반응특성

손병현(Byung-Hyun Shon),오광중(Kwang-Joong Oh),김영식(Young-Sick Kim) 한국청정기술학회 1996 청정기술 Vol.2 No.1

혼합 망간계 탈황제에 의한 고온 황화반응에 관한 연구

손병현(Byung Hyun Shon),오광중(Kwang Joong Oh),김영식(Young Sick Kim) 大韓環境工學會 1997 대한환경공학회지 Vol.19 No.8

電氣泳動法에 依한 犬 齒根膜의 銀染色

金永植 中央醫學社 1968 中央醫學 Vol.14 No.4

The silver stain ability of the periodontal ligament in the mandible of the mature dog was observed by means of the electrophoresis of Monroe, Spector and Harris. In these experimental results, it was found that the periodontal ligament had primarily brownish black fibers, and there were yellowish brown fibers in the cemental side and bone forming side of the periodontal ligament, and among brownish black fibers.

응급센터내에서의 Do-Not-Resuscitate Order

김영식,황성오,이부수,안무업,임경수,강성준 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Do-not-resuscitate(DNR) decision in certain patients is a important part of patient management. The use of DNR order has been widely recognized in hospitalized patients, but there has been little discussion of the use of DNR order in emergency department. DNR decision in emergency department is difficult because there is no previous contact between physician and patient. To identify the medical reasons of the DNR decision and the process of the DNR in the emergency department, 293 DNR patients in emergency department during 1 year and 36 physicians having experienced DNR decision were studied. Reasons for DNR are irreversible states from brain damage or acute illness(63%), chronic irreversible illness(15%), prolonged cardiac arrest over 30 minutes(16%), physical injuries including decapitation(1%) and family's hope(5%). Almost DNR(72%) were decided by physicians. 72% of DNR decision were not documented. Cardiopulmonary resuscitation was attempted before DNR decision in 38% of the patients and 17% of CPR attempts were unnecessary. Almost physician(88%) replied that physician should discuss resuscitation with family and process of DNR decision should be documented.

Pyridoxine 投與한 白鼠琺瑯質形成에 있어 組織化學的 燐酸反應에 關한 硏究

金永植 대한치과의사학회 1989 대한치과의사학회지 Vol.10 No.4

Pseudomonas sp. TPP 63을 이용한 PVA 폐수의 생물학적처리에 관한 연구

김영식,조상원,오광중,임주원 부산대학교 환경문제연구소 1994 環境硏究報 Vol.12 No.-

The purpose of this study is increasing the microbiological treatment efficiency of PVA wastewater using selected bacteria. The bacteria which showed high decomposition rate of PVA was separated as TPP 63 bacteria decomposing PVA of 91.3% when the bacteria have cultured at 0.5% PVA minimum culture medium for 5 days. This bacteria was identified as Pseudomonas putida. It showed a maximum decomposition rate of PVA at culture temperature of 37℃ and pH 7.5-7.8. In case 0.2% PVA wastewater was treated with this culture of 3500 mg/L MLSS, the efficiency was improved with increasing HRT. At HRT of 5 days and 0.4% PVA concentration, the treatment efficiency was dropped down more seriously when the culture medium was not supplied.

稀有한 癒合齒例

金奭潤,金永植 醫藥係社 1955 綜合 醫學 Vol.12 No.9

토마토의 Allelopathy에 關한 硏究

姜成庸,金永植 조선대학교 농업연구소 1986 農業硏究 Vol.1986 No.1

토마토 식물의 allelopathy 效果를 究明하기 위하여 토마토 식물 기관의 물 추출액과 휘발성 물질이 다른 식물의 다른 식물의 발아와 생장을 억제함을 확인하고 그 원인을 Paper chromatography, High performance liquid chromatography 및 gas chromatography를 이용하여 검출 분리한 후 관계하는 물질의 標品으로 상치와 가지의 발아와 생장 억제를 확인함으로써 ferulic acid와 vanillic acid가 관계하는 것으로 나타났다. 실험결과를 要約하면 다음과 같다. 1. 토마토 식물의 잎 抽出液은 줄기나 뿌리의 抽出液보다 발아 억제 작용이 컸고 상치, 조, 참소리쟁이의 생장을 억제하였으나 무우와 배추는 큰 영향을 받지 않았고 맨드라미는 오히려 생장이 촉진되었다. 다만 추출시간이 길어짐에 따라 실험에 사용된 식물에게 억제효과가 크게 나탄났다. 2. 토마토 식물의 leachate는 가지와 상치의 伸張을 約 50% 억제하고 건중량도 감소시켰다. 3. U자관화분에서 토마토 식물과 다른 식물을 한쌍으로 組合하여 재배한 결과 토마토 식물의 뿌리에서 배추, 수수, 들깨 및 옥수수의 생장을 억제하는 물질을 분비하는 것이 관찰되었다. 4. Paper chromatography로 토마토 식물의 잎 추출물을 분석한 결과 gallic acid, ferulic acid. p-hydroxybenzoic acid 및 salicylic acid의 5종이 검출되었고 high performance liquid chromatography로 토마토 식물의 잎, 줄기 및 뿌리 추출물을 분석하면 tannic acid, hydroquinone, p-hydorxybenzoic acid, vanillic acid 및 ferulic acid의 5종이, gas chromatography로 추출물에서 hydroquinone과 tannic acid의 2종이 검출되었다. 5. 검출된 phenolic compounds로 상치와 가지의 발아와 생장을 측정한 결과, 5×10^3M 농도에서 두 식물이 모두 발아되지 않았고 5×10^(-4)M 농도에서도 생장이 억제되었다. 6. 화분 재배한 상치는 5×10^(-3)M의 hydroquinone과 p-hydroxybenzoic acid에서 전혀 발아되지 않았고, ferulic acid, vanilic acid 및 tannic acid에서 발아는 되었지만 枯死시키고, 5×10^(-4)M 농도에서도 생장억제가 크게 나타났다. 7. 토마토 식물 옆에 재배한 상치의 乾重量이 감소되고 포도나무는 伸張과 乾物量生長이 억제되었다. 8. 토마토 식물의 휘발성물질은 ferulic acid와 vanillic acid이며 특히 前者는 발아와 생장실험에 의하여 토마토의 allelopathy에 관계되는 原圖物質이라고 생각된다. These studies were to verify allelopathy of tomato plant, that inhibits germination and growth of other plants than the tomato plant treated with the water extract and volatile substance from the tomato plants. The experiments were consisted of three steps: first, effects of the water extract from the tomato plant on the germination and growth of another plants, second, phenolic compounds as allelochemicals of tomato plant were isolated and identified by procedures of paper chromatography (PC), high performance liquid chromatography (HPLC) and gas chromatography (GC), third, inhibition of the germination and growth of lettuce and egg plant were certified by treatment with phenolic compounds identified above. Inhibition of the germination of lettuce seed is greater than those of another plants by treated with tomato leaf extract and the germination percentage is decreased by treatment with both stem and root extracts as extracting time elapses. The leaf extract more inhibits the germination of the seeds than both stem and root ones. The leaf extract decreases the growths of Setaria italica, Laduca sativa and Rumex japonicus but not Raphamus sativus var. hortensis and Brassica campestrtis subsp. napus var. pekinensts, opposirely, rather accelerates the growth of Celosia cristata. Leachate collected from the tomato plants decreases as much as 50 % of the growths in elongation as well as in dry weight of seedlings of lettuce and egg plant. It is observed that with a paired-plants grown in U tube pot the tomato roots excrete allelochemicals to inhibit. the growth of Sorghum bicolor, perilla frulescens var. japonica, Zea mays and Brassica campestris subsp. napus var. pekinensis. With the extract from tomato plant phenolic compounds such as gallic acid, ferulic acid, p-hydroxybenzoic acid, vanillic acid and salicylic acid are separated by procedure of the PC, tannic acid, hydroquinone, p-hydroxybenzoic acid, vanillic acid and ferulic acid by the HPLC and only the former two compounds by the GC. It is certified that such phenolic compounds with concentration of 5×10^ 3M inhibit the germination and growth of lettuce and egg plant grown in a Petri dish culture for short period. In contrast with the 5×10^-3M solution of hydroquinonc and p- hyd roxybcnzoic acid completely inhibit the germinations, of both plants and ferulic acid, vanillic acid and tannic acid with the same concentration are able to germinate the seeds but to wilt the seedlings in pot culture for long period. Both lettuce and grape vine grown near the tomato plants in vinyl house were inhibited the growth in elongation as well as in dry weight. It would be due to volatile substances perfuming the tomato plants, 'which are both ferulic acid and vanillic acid to be detected by HPLC. It is possible that these volatile substances may be a par t of the allelochemicals of the tomato plants.