치조골 신장술 후 발생한 문제점의 해결책 및 예방법 : 증례보고

김영란,김여갑,이백수,권용대,윤병욱,최병준,유용재,오정환,Kim, Young-Ran,Kim, Yeo-Gab,Lee, Baek-Soo,Kwon, Yong-Dae,Yoon, Byung-Wook,Choi, Byung-Joon,Yu, Yong-Jae,Oh, Jung-Hwan 대한악안면성형재건외과학회 2008 Maxillofacial Plastic Reconstructive Surgery Vol.30 No.5

For the successful placement of dental implants, adequate alveolar bone height and width are required. Alveolar distraction osteogenesis is an effective method that resolves insufficient alveolar bone height for dental implant placement, and thus has been clinically applied with satisfactory results. But, minor and major problems may occur during the treatment. In the following report, we studied for such problematic cases. The problems are as follows: 1) sharp edges of the transport segment, 2) infection, 3) soft tissue dehiscence, 4) limitation of distraction, 5) numbness, 6) insufficient bone formation. But, most of them were answered by simple solutions and did not jeopardize the final outcomes. Distraction osteogenesis can be considered a safe and predictable procedure for lengthening the alveolar bone.

3가지 형태의 백악질-골성 이형성증에 대한 증례보고

김영란(Young Ran Kim),김여갑(Yeo Gab Kim),이백수(Baek Soo Lee),권용대(Yong-Dae Kwon),최병준(Byung Joon Choi) 대한구강악안면외과학회 2009 대한구강악안면외과학회지 Vol.35 No.6

Cemento-osseous dysplasias are a group of disorders known to originate from periodontal ligament tissues and involve, essentially, the same pathological process. They are usually classified, depending on their extent and radiographic appearances, into three main groups. Periapical cemental dysplasia predominantly involves the periapical region of the anterior mandible. Florid cemento-osseous dysplasia presents with multifocal lesions in the tooth bearing or edentulous areas of the maxilla and mandible, often occurring bilaterally with symmetric involvement. Focal cemento-osseous dysplasia exhibits a single site of involvement in any tooth bearing or edentulous area of the mandible or maxilla, with the posterior mandible representing the most common site. We report the clinical, radiographic and histological findings of 3 types of cemento-osseous dysplasia with a review of literatures.

소프트웨어 재사용 시스템을 위한 인덱스 - 릴레이션 구조 설계

김영란(Yong-Ran Kim),구연설(Yeon Seol Koo) 한국정보과학회 1990 한국정보과학회 학술발표논문집 Vol.17 No.2

소프트웨어 개발 능력 및 생산성을 향상시키기 위한 방법론중의 하나가 소프트웨어 재사용론이며, 효율적인 재사용을 위해서는 분류와 검색과정이 매우 중요하다. 따라서, 본 연구에서는 소프트웨어 재사용 시스템을 위해 component를 효율적으로 분리하여, 사용자 요구사항에 가장 밀접한component를 제공할 수 있는 인덱스-릴레이션 구조(IRS Index-Relation Scheme)를 고안하였으며, 이를 이용한 소프트웨어 재사용 시스템을 설계하였다.

Alendronate와 Pamidronate가 인간 골수유래 간엽줄기세포의 증식과 알칼리성 인산분해효소 활성에 미치는 영향

김영란(Young Ran Kim),류동목(Dong-Mok Ryu),권용대(Yong-Dae Kwon),윤영필(Yong PilYun) 대한구강악안면외과학회 2009 대한구강악안면외과학회지 Vol.35 No.6

The purpose of this study is to investigate the effects of alendronate and pamidronate on proliferation and the alkaline phosphatase activity of human bone marrow derived mesenchymal stem cells and to relate the results with bisphosphonate related osteonecrosis of the jaw(BRONJ). With the consent of patients with no systemic disease and undergoing iliac bone graft, cancellous bone was collected to obtain human bone marrow derived mesenchymal stem cells through cell culture. 96 well plate were prepared with a concentration of 104cell/ well. Alendronate and pamidronate were added to each well with the concentration of 10-6M, 10-8M and 10-10M, respectively. Then proliferation capacity of each well was evaluated with the cell counting kit. 24 well plates were prepared with a concentration of 105cell/ml/well and with the bone supplement, alendronate and pamidronate were added with the concentration of 10-6M, 10-8M and 10-10M, respectively on each plate. The plates were cultured for either 24 or 72 hours. Then the cells were sonicated to measure the alkaline phosphatase activity and protein assay was done to standardize the data for analysis. As the concentration of alendronate or pamidronate added to the culture increased, the proliferation capacity of the cells decreased. However, no statistical significance was found between the group with 10-10M of bisphophonate and the control group. Pamidronate was not capable of increasing the alkaline phosphatase activity in all trials. However, alkaline phosphatase activity increased with 24 hours of 10-8M of alendronate treatment and with 48 hours of 10-10M of alendronate treatment. Cell toxicity increased as the bisphosphonate concentration increased. This seems to be associated with the long half life of bisphosphonate, resulting in high concentration of bisphosphonate in the jaw and thus displaying delayed healing after surgical procedures. Alendronate has shown to increase the alkaline phophatase activity of human bone marrow derived mesenchymal stem cells. However, this data is insufficient to conclude that alendronate facilitates the differentiation of human bone marrow derived mesenchymal stem cells. Further studies on DNA level and animal studies are required to support these results.

한국인 치과의사의 비스포스포네이트 관련 악골괴사에 대한 인식 연구

박용덕(Yong-Duck Park),김영란(Young-Ran Kim),김덕윤(Deog-Yoon Kim),정윤석(Yoon-Sok Chung),이정근(Jeung-Keun Lee),김여갑(Yeo-Gab Kim),권용대(Yong-Dae Kwon) 대한구강악안면외과학회 2009 대한구강악안면외과학회지 Vol.35 No.3

Recently, an increasing number of bisphosphonate related osteonecrosis of the jaw(BRONJ) is being reported. A guideline has been already established in the US, but it does not seem to be fully recognized by clinicians in Korea. Therefore, a survey study was done to inform and have clinicians realize the seriousness of BRONJ. 1,341 practitioners were randomly selected out of 13,405 practitioners(by Feb of 2008, KDA) in Korea. A questionnaire was given to them between May to July in 2008. Questions were designed to investigate each respondent’s experience term years in the clinic, occupation, speciality, awareness on risk of bisphosphonate, experience on treating osteonecrosis patients, awareness about the guideline on BRONJ suggested by AAOMS and whether if they ask about bisphosphonate medication history to patients before invasive treatment. 45.1% of the clinicians have reported on experiencing delayed healing on bone exposed site after extraction both in the maxilla and the mandible. However, clinicians have asked the patients whether if they are on bisphosphonate or not in only 15.1% of these cases. 56.5% of the clinicians simply knew about BRONJ but only 28.9% of the clinicians were aware that bisphosphonate can cause osteonecrosis after invasive dental treatment. Only 19.3% knew about the contents of guideline on BRONJ and 57.2% were aware of the seriousness of BRONJ. Clinicians with shorter clinical experience term were more aware of BRONJ and the guideline on BRONJ than the experienced clinicians. But awareness of the possibility of BRONJ after invasive dental treatment were about the same regardless of their clinical experience. The results show that Korean clinicians need to be more aware about BRONJ. Data on BRONJ cases in Korea should be collected and provided with additional education to let Korean clinicians know and be more aware about BRONJ.

카페인 섭취가 흰쥐의 혈청내 지질과 무기질 함량에 미치는 영향

김명희 ( Myung Hee Kim ),김영란 ( Yong Ran Kim ),이종완 ( Jong Wan Lee ),박병권 ( Byung Kwon Park ),김민규 ( Min Kyu Kim ),최미경 ( Mi Kyeong Choi ),김애정 ( Ae Jung Kim ) 한국식품영양학회 2008 韓國食品營養學會誌 Vol.21 No.3

This study was conducted to investigate the effects of caffeine on lipid and mineral content in the serum of rats given a caffeine free diet(FC), a low caffeine diet(LC), a medium caffeine diet(MC), a high caffeine diet(HC) or a super-high caffeine diet(SHC) for 5 weeks. Thirty male Sprague-Dawley rats(body weight, 110±0.3 g) were blocked into 5 groups and fed diets with or without pure caffeine. Caffeine intake models showed a lower mean-weight gain, food intake and food efficiency in the high caffeine diet groups(MC, HC and SHC groups) than the groups receiving a caffeine free or low caffeine diet(FC and LC groups). Serum total lipid, total cholesterol and LDL-cholesterol levels decreased, but the serum HDL-cholesterol level increased according to the increase in caffeine intake. Serum total lipid, HDL-cholesterol and serum triglyceride were significantly lower in the HC and SHC groups than the FC group. All of the serum minerals decreased as caffeine intake increased. Serum iron, calcium, magnesium and phosphorus significantly decreased in the HC and SHC groups compared to the FC group. Caffeine intake was associated with less weight gain and reduced serum total cholesterol, triglyceride and total lipid. The results suggest that rats fed high amounts of caffeine may be susceptible to osteoporosis due to their low levels of calcium, magnesium and phosphorus.

복강경하 자궁각절제술과 자궁경부이형성증 병력있는 환자에서 임신 제3분기에 일어난 연속적인 자궁파열사례

김영란 ( Young Ran Kim ),문명진 ( Myung Jin Moon ),장성운 ( Sung Woon Chang ),안은희 ( Eun Hee Ahn ),장항용 ( Hang Yong Jang ),이경미 ( Gyong Mi Lee ),정상희 ( Sang Hee Jong ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.12

Uterine rupture during the course of pregnancy is an uncommon obstetric event. Rupture of an unscarred uterus is rare, whereas rupture of a scarred uterus is more common and is usually the result of a Cesarean section. Uterine rupture during pregnancy usually occurs in patient with a scarred uterus, and recurrent uterine rupture usually occurs at a prior ruptured site. However, recurrent uterine rupture that occurs at a different site, regardless of prior rupture site, has yet to be reported. The patient described in this case report had cervical dysplasia with positive for human papilloma virus (HPV) type 16. As the presence of a precancerous lesion in the cervix is reported to increase the risk of preterm birth and spontaneous uterine rupture, a possible correlation between recurrent uterine rupture and cervical dysplasia was considered for this patient.

병․의원에 근무하는 방사선사들의 이직의사에 관련된 요인

김영란(Young-Ran Kim),이태용(Tae-Yong Lee),천해경(Hae-Kyung Cheon) 대한방사선과학회(구 대한방사선기술학회) 2009 방사선기술과학 Vol.32 No.4

병원규모에 따라 조직문화와 인사체계가 다르기 때문에 이들 병원에서 근무하는 방사선사의 이직요인에 차이가 있을 가능성이 충분히 있으므로, 본 연구는 대전광역시 지역 종합병원과 개인병원에 근무하는 방사선사를 대상으로 이들의 이직의사 수준을 알아보고 이직의사와 인구사회학적 특성, 직업관련 특성, 직무스트레스 요인, 직무만족도, 직무성과, 조직몰입 등의 제 요인과의 관련성을 알아보고자 하였다. 2008년 6월 1일부터 6월 30일까지 대전소재 5개 종합병원에서 근무하는 방사선사 158명, 의원에 종사하는 방사선사 117명 총 275명을 대상으로 자기기입식 설문조사(self-administered questionnaire)를 실시하였다. 위계적 다중회귀분석을 실시한 결과 개인병원은 교육수준, 직무스트레스 중 업무요구도, 직무만족도가 이직의사에 영향을 미쳤으며, 종합병원은 연령, 근무시간, 직무만족도, 조직몰입이 이직의사에 영향을 미쳤다. 이는 병원의 인사관리 및 조직관리 시 자료로 고려되어야 할 것으로 생각된다. his study was executed to find out the intensity of turnover and its associated factors of radiologic technologists who worked for private clinic and university hospitals in Daejoen. Such variables as social and demographic characteristics, job-related features, job stress, job satisfaction, job performance, organizational commitment and turnover intention were investigated based on the survey of randomly sampled 400 radiologic technologists. The results are summarized as follows. 1. College graduates of private clinic workers significantly higher than junior college graduates of them in the mean score for turnover intention. And low age groups, unmarried group, no religion group, low job career groups and low income groups of university hospital workers were significantly higher than high age groups, married group, religion group, high job career groups and high income groups of them respectively in the mean score for turn over intention. 2. private clinic and university hospital workers' low and high groups in the variables of job demand, job control, supervisor support, job satisfaction, organizational commitment showed significant difference in the mean score for turnover intention. specially private clinic workers' low and high groups in the variables of coworker support, job performance showed significant difference in the mean score for turnover intention. 3. A hierarchial multiple regression analysis was conducted to catch the influence of related variables on turnover intention according to private clinic workers and university hospital workers. As a result of the analysis, the higher the degrees of education and job demand were and the lower the degree of job satisfaction was for private clinic workers, the higher the degree of turnover intention was. And the lower the degrees of age, job career, job satisfaction and organizational commitment were for university hospital workers, the higher the degree of turnover intention was. In conclusion, it was found that job demand and job satisfaction for private clinic workers and job satisfaction and organizational commitment for university hospital workers influenced on turnover intention.

Radiator cooling fan용 스위치드 릴럭턴스 전동기의 구동 시스템

김영란(Young-Ran Kim),윤용호(Yong-Ho Yoon),이상석(Sang-Suck Lee),정동효(Dong-Hyo Jung),원충연(Chung-Yuen Won) 전력전자학회 2004 전력전자학술대회 논문집 Vol.- No.-

In automobile, the introduction of electronically commutated motors has been accompanied by a proliferation of electronic devices. With this proliferation of electronic devices, an emphasis has been placed on EMC issues. This paper is proposed to use SRM as a radiator cooling fan in automotive applications. To drive SRM, Energy efficient C-dump converter is applied. It is verified more efficient than other converters through simulation and experiments. And also SRM is valid automotive applications that have strict EMC standards. It is compared SRM with BLDC and DC motor by experiments.

종합병원 교대근무 여성들의 생활습관 및 영양섭취상태가 골밀도 값에 미치는 영향

김영란(Young-Ran Kim),이태용(Tae-Yong Lee),박영선(Young-sun Park),천해경(Hae-Kyung Cheon) 대한방사선과학회 2012 방사선기술과학 Vol.35 No.1

본 연구는 생활주기가 불규칙한 종합병원에 5년 이상 근무한 만 30세 이상의 교대근무여성 총 232명을 연구대상으로 생활습관과 영양섭취상태를 조사하고, 골밀도와의 관련성을 살펴봄으로써 교대근무여성의 골 질환 예방을 위한 기초자료를 제공하는데 목적이 있다. 연구의 목적을 이해하고 참여에 허락한 교대근무여성들의 골밀도를 측정하고, 혈액 검사를 통한 생화학적 검사로 혈청 알부민, 총 단백질, 총 콜레스테롤, 헤마토크리트, 헤모글로빈, 칼슘, 인등을 측정하였으며, 그 결과 일반적 특성 및 생활 습관, 총콜레스테롤, 총 단백질, 알부민, 칼슘, 인, 헤모글로빈, 헤마토크리트를 독립변수로, 골밀도를 종속변수로 하여 골밀도에 영향을 미치는 관련 변수들의 설명력을 파악하기 위해 다중회귀분석을 실시하였다. 분석결과 운동, 음주, 칼슘, 인이 유의한 변수로 선정되었으며, 이들의 설명력은 10.2%였다. 즉 운동을 하지 않은 군보다 운동을 한 군일수록, 비음주군보다 음주군일수록, 칼슘이 많은 군일수록, 인이 많은 군일수록 골밀도가 유의하게 높았다. 3교대 조사대상자들의 불규칙한 생활습관으로 인한 골다공증을 예방하기 위해서는 규칙적인 운동이 필요하며 칼슘과 인을 1 : 1 비율로 섭취하는 식이습관이 중요하다고 판단된다. The purpose of this study is to provide preliminary data for bone disease prevention by examining the correlation between bone mineral density, and lifestyle and nutritional status of female shift workers, at general hospitals with an irregular life cycle. The subjects for this study were 232 female shift workers, over 30 years old, who worked at a general hospital more than 5 years. From the subjects, who understood the purpose of this study and decided to be participated, we measured serum albumin, total brotein, total cholesterol, hematocrit, hemoglobin, calcium, phosphorus from blood test, and obtained bone mineral density. To analyze the effectiveness of the variables for explanation power, we established the studied values as independent variables, bone minral density as a dependent variable. Exercise, the number of drinking , calcium, and phosphorus were selected as significant variables and the explanation power was 10.2%. The bone mineral density were significantly higher at the subjects who had exercise, higher calcium and phosphorus possession, and drank alcohol than the opposite cases. Regular exercise, and 1:1 intake of calcium and phosphorous were important to prevent osteoporosis for the subjects who were working three shifts which cause irregular lifestyle.