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      • KCI등재

        망막분지정맥폐쇄 황반부종에서의 유리체강내 트리암시놀론 주입술 후 시력호전의 예후인자

        김숙진,문연성,Suk Jin Kim,Yeon Sung Moon 대한안과학회 2012 대한안과학회지 Vol.53 No.1

        Purpose: To evaluate prognostic factors for improvement of visual acuity after intravitreal triamcinolone acetonide injection (IVTA) for treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods: Sixty-eight eyes of 68 consecutive patients treated with IVTA for ME due to BRVO were retrospectively reviewed. Patients were categorized into 2 groups according to the final visual acuity. The ‘gainer group’ consisted of eyes with a gain of 2 or more Snellen chart lines and the ‘non-gainer group’ consisted of eyes with less than 2 lines improvement or which had worsened at the last follow-up visit. Comparative clinical characteristics and ophthalmoscopic examinations were analyzed between the 2 groups. Results: Out of the 68 eyes, 38 (56%) showed improved vision and were categorized as the gainer group; 30 eyes (44%) were categorized as the non-gainer group. The duration of symptoms in the non-gainer group was longer than the gainer group. Additionally, patients with a better baseline vision were expected to show greater improvement. The number of early visual acuity gainers who showed visual improvement at 1 month after IVTA was significantly higher in the gainer group. The number of eyes with angiographically documented macular ischemia was significantly higher in the non-gainer group. Existence of subretinal fluid has been identified as a positive factor for visual improvement. Conclusions: The cases with early treatment, good baseline visual acuity, case of favorable response to the initial IVTA, absence of macular ischemia, and baseline subretinal fluid are favorable prognostic factors for the outcome of visual acuity after IVTA for ME due to BRVO. J Korean Ophthalmol Soc 2012;53(1):49-58

      • KCI등재

        편측성 급성 특발성 황반병증에서의 다양한 진단 이미지 검사

        김숙진,김기석,Suk Jin Kim,Ki Seok Kim 대한안과학회 2015 대한안과학회지 Vol.56 No.1

        Purpose: To report multimodality diagnostic imaging in a case of unilateral acute idiopathic maculopathy. Case summary: A 32-year-old woman with reduced vision in the right eye had experienced fatigue and flu-like symptoms, including sore throat and fever a few days before. Her best corrected visual acuity (BCVA) was 1.0 in the right eye. There were no cells in the anterior chamber and vitreous. Fundus photographs of the right eye on presentation showed gray-white thickening of the fovea and retinal hemorrhage next to the fovea. Fluorescein angiography demonstrated ring-shaped mottled hyperfluorescence in the early phase and dye pooling in the late phase. Spectral-domain optical coherence tomography (OCT) showed abnormal hyper-reflective thickening at the level of the outer retina and retinal pigment epithelium (RPE) and detachment of the neurosensory retina in the foveal lesion. The inner segment/outer segment junction and photoreceptor elevation/disruption was noted. Nineteen months after onset, the BCVA of the right eye was 1.0 and fundus photographs showed increased retinal pigment hyperplasia, and residual RPE changes resembling a bull’s eye maculopathy. The OCT of the right macula showed that the inner segment/outer segment junction elevation/disruption almost completely regressed. The patient was diagnosed with unilateral acute idiopathic maculopathy. Conclusions: We report a typical case with flu-like symptoms of unilateral acute idiopathic maculopathy. It is a very rare macular disease and a case such as ours with long-term follow-up using multimodality diagnostic imaging has not been previously reported. J Korean Ophthalmol Soc 2015;56(1):142-147

      • KCI등재

        갑상선안병증 환자의 일차배양한 안와섬유모세포에 대한 알파-토코트리에놀의 항섬유화 효과

        김숙진,강행구,강성모,Suk Jin Kim,Haeng Ku Kang,Sung Mo Kang 대한안과학회 2012 대한안과학회지 Vol.53 No.2

        Purpose: To evaluate the antiproliferative and antifibrotic effects of α-tocotrienols in primary cultured orbital fibroblasts from thyroid-associated ophthalmopathy (TAO) patients. Methods: Orbital fibroblasts were cultured (5 eyes from TAO patients, 5 eyes from normal patients) and classified into a control group, α-tocotrienol group and α-tocopherol group. The cell viability was measured using the 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyl tetrazolium bromide (MTT) assay. The proliferation of orbital fibroblasts was measured using the Click-iTTM assay. The collagen production of the control and α-tocotrienol groups was measured using a hydroxyproline assay. Results: The α-tocotrienol and α-tocopherol groups showed no cytotoxicity up to 150 μm in orbital fibroblasts from TAO and normal patients. The proliferation of orbital fibroblasts from TAO and normal patients was significantly inhibited with α -tocotrienol at 80 μm and 120 μm. The collagen production of orbital fibroblasts from TAO patients was significantly inhibited with α-tocotrienol at 120 μm. Conclusions: The results from the present study indicate that non-toxic concentrations of α-tocotrienol have significant antiproliferative and antifibrotic effects on orbital fibroblasts from TAO patients. J Korean Ophthalmol Soc 2012;53(2):323-332

      • KCI등재

        양안 황반부 모세혈관 확장증과 연관된 양안 황반 원공 1예

        김숙진,김기석,Suk Jin Kim,MD,Ki Seok Kim,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.9

        Purpose: To report a case of bilateral macular holes in a patient with bilateral macular telangiectasia (Mac Tel). Case summary: A 61-year-old male presented with decreased central vision in both eyes. His best corrected visual acuity (BCVA) was 0.8 in the right eye and 0.6 in the left eye. On fundoscopy, fluorescein angiography (FAG), and optical coherence tomography (OCT), he was diagnosed with Mac Tel type 2 combined with stage 1A of the right eye and stage 1B impending macular hole in the left eye. Two years and 8 months later, the BCVA of both eyes was unchanged. On fundoscopy, FAG and OCT, there were no definitive changes in both eyes. The patient was observed without treatment. Conclusions: Patients with Mac Tel type 2 may be predisposed to the development of a macular hole.

      • KCI등재
      • KCI등재

        몽골과 미얀마 식물 14종의 3T3-L1 및 HepG2 세포에서 지질 축적 억제효과

        김숙진,김건희,Kim, SukJin,Kim, Gun-Hee 한국식생활문화학회 2021 韓國食生活文化學會誌 Vol.36 No.1

        This study examined the antioxidative and lipid accumulation inhibitory effects of 14 plants from Mongolia and Myanmar on 3T3-L1 and HepG2 cells. The total phenolic and flavonoid contents (TPC and TFC) of 14 plant extracts were measured, and the antioxidative activities were analyzed using DPPH, ABTS, FRAP, and ORAC. After measuring the pancreatic lipase levels and performing the thiobarbituric acid assay, the degree of lipid accumulation was determined by lipid (Oil Red O) staining and triglyceride assay in 3T3-L1 and HepG2 cells. M. paniculate (259.43 mgGAE/g) and C. benghalensis (130.78 mgNAE/g) had the highest TPC and TFC, respectively, among the 14 plants. R. acicularis Lindl. had the highest antioxidant activity in DPPH. The ABTS, FRAP, and ORAC results showed that the antioxidant activity of 11 species was higher than that of the positive control. The pancreatic lipase inhibitory effect of C. angustifolium Scop. was reduced to 23.65% at 0.1 mg/mL, and the level of lipid peroxidation of C. abrorescens Lam. was 0.63 nmol/mg. Five selected plants inhibited the lipid accumulation and triglyceride content, respectively, in 3T3-L1 and HepG2 cells. These results provide scientific evidence for developing functional foods using 14 plants from Mongolia and Myanmar, which have antioxidant activities and lipid accumulation reduction effects.

      • 2020 이주 노동자 자살예방을 위한 정신건강실태조사

        김숙진(Suk Jin Kim),송후림(Hoo Rim Song),김미선(Mi Sun Kim),이애란(Ae ran Lee),김유나(Yu Na Kim),김선영(Sun Young Kim),이서정(Seo Jung Lee) 대한사회정신의학회 2022 사회정신의학 Vol.27 No.1

        목 적 : 본 연구는 이주 노동자 자살 예방사업 일환으로 이주 노동자들의 전반적 정신건강 실태와 자살에 대한 인식 및 경험에 대해 파악하여 시사점을 도출하고자 하였다. 방 법 : 2020년 6월 11일부터 7월 23일까지 국내에 거주하는 네팔, 중국, 미얀마 3개국 출신의 이주 노동자 총 102명을 대상으로 전반적 인구학적 정보 및 정신건강 실태 조사를 위해 우울감에 대한 자가 척도(The Center for Epidemiologic Studies Depression Scale [이하CES-D])를 수집하였다. 결 과 : 조사 참여자들은 스스로 느끼는 자신의 전반적 건강 상태가 보통 이상인 경우가 95명(93.1%), 주관적 행복감이 보통 수준 이상인 경우 90명(88.2%)이었다. 자가 보고형 우울 척도인 CES-D의 평균 점수는 13.9±10.4점으로 나타났다. CES-D 점수 분포는 15점 이하로 정상 범위가 68명(66.6%), 16-20점 사이로 경도 우울 상태가 13명(12.7%), 21-24점으로 중등도 우울 상태가 6명(5.8%), 25점 이상으로 고도 우울 상태가 15명(14.7%)이었다. 출신 3개국 간 CES-D 평균 점수는 통계학적으로 차이가 없었으나, 21점 이상 우울군은 네팔 출신 노동자들이 높게 나타났다. 결 론 : 본 연구에서는 다수의 이주 노동자들의 우울 점수가 정상 범위로 나타났으나, 우울 상태에 해당되는 경우에는 경도나 중등도 우울 상태인 비율보다 상대적으로 고도 우울 상태인 비율이 높게 나타났다. 이는 향후 이주민 노동자들 전반에 걸친 정신건강 서비스에 더하여 고도의 우울, 즉, 자살 고위험군을 발굴하고 이에 초점을 맞춘 서비스 개발이 필요함을 시사한다. Objectives : This study aimed to examine Korean migrant workers’ mental health status and perceptions and the experiences of suicide as part of suicide prevention program to derive its social implications. Methods : A sample of 102 migrant workers from Nepal, China, and Myanmar residing in Korea from June 11th to July 23rd, 2020 completed a self-administered depression scale (The Center for Epidemiologic Studies Depression Scale [CES-D]). Re-sponses were collected to investigate participants’ demographic data and mental health condition. Results : Of the survey participants, 95 (93.1%) had greater than average mental health status, and 90 (88.2%) participants' subjective feeling of their well-being was above average. The average score for CES-D was 13.9±10.4 points. The distribution of CES-D scores was in the normal range (≤15 points) in 68 (66.6%) participants, 13 (12.7%) participants had mild depressive status, 6 (5.8%) participants had moderate depressive status (21-24 points), and 15 (14.7%) participants had a high depressive status (≥25 points). There was no statistically significant difference in the average CES-D scores of migrant workers from the three countries of origin, but workers from Nepal showed higher scores in the high depressive status group, with scores of 21 or higher. Conclusion : In this study, most migrant workers demonstrated a normal mental health status. Regarding those in a depressive state, the proportion of those in a high depressive state was relatively higher than that of those in a mild or moderate depressive state. This result suggests that in addition to mental health services targeting migrant workers, it is necessary to discover groups at high risk of high-level depression and suicide to develop services focusing on them.

      • KCI등재

        생물권보전지역의 지속가능한 발전 -운곡습지의 생태관광을 중심으로-

        김숙진 ( Sook-jin Kim ) 한국사진지리학회 2017 한국사진지리학회지 Vol.27 No.1

        운곡습지는 1981년 영광원자력발전소를 건설하면서 냉각수 공급을 위한 댐건설로 사람들의 인적이 끊기자폐경된 논밭이 원시습지 형태로 자연 복원되어, 2011년 습지보호지역과 람사르 습지로 등록되었고, 2013년에는 유네스코 생물권보전지역으로 지정되었다. 본 연구는 운곡습지 사례를 통해 우리나라 환경정책이라는 큰 틀에서 자연환경보전 정책의 패러다임 변화가 어떻게 운곡습지에 대한 재인식과 보전에 영향을 미쳤는지, 그리고 최근 생태관광을 통해 지속가능한 발전을 꾀하게 되었는지 그 변화양상을 고찰하였다. 운곡습지 용계마을은 지속가능한 발전의 핵심으로 여겨지는 주민들의 적극적 참여를 기반으로 마을기업을 중심으로 생태체험 프로그램을 운영하고 있으며, 최근에는 생물권보전지역 인증로고 제도나 람사르습지 도시 인증과 같은 브랜드화 노력을 통해 보전뿐만 아니라 지역의 지속가능한 발전을 위한 지역경제 활성화를 꾀하고 있어 다른 지역의 생태관광에 중요한 시사점을 제공한다. Ungok Wetland was restored as primitive wetland after being left out for thirty years since Ungok dam had been built to provide coolant for Yeonggwang Nuclear Power Plant. It was designated as wetland conservation area and Ramsar Wetland in 2011 and UNESCO Biosphere Reserves in 2013. This paper investigates how the paradigmatic shifts in the Korean environmental policy have affected the recognition and conservation of Ungok Wetland, and how the community of Yonggye Maeul has pursued eco-tourism for sustainable development. Yonggye Maeul runs ecological experience programs through its Maeul enterprise based on community`s active participation, and recently attempts for branding of Biosphere Reserves and Ramsar Wetland City Accreditation aiming for economic revitalization and eventually sustainable development.

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