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김성규,Kim, Seong-Kyu 한국항해항만학회 2001 한국항해학회지 Vol.25 No.2
This paper presents the educational methodology shipboard training methods of Maritime Colleges in U.S.A. and the fields of engagement in business of the graduates from them. There are two Maritime Academies, i.e. U.S. Merchant Marine Academy (USMMA) and U.S. Coast Guard Academy, which are supported by federal government and six Maritime Colleges operated by each State. Maritime Administration (MARAD) in the Department of Transportation (DOT) supports the training of merchant marine officers and crew members with a focus on safety in U.S. waterborne commerce. The shipboard training methods are not unique, but have various process. One is continuous sea term training onboard during sophomore (100 days) and junior year (200 days) in case of USMMA, the other is summer sea term training onboard every three months during freshman, sophomore and junior years in case of SUNY Maritime College. They offer also one month ship simulator training ashore. The employment status for the 1999 year graduates from USMMA shows 43 percent in the field of maritime afloat, 34 percent of maritime ashore, 22 percent of active duty military and 1 percent of others.
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독소루비신을 함유하고 단백질로 수식된 양이온성 리포솜의 제조 및 혈장 단백흡착 특성
김성규,정순화,정석현,성하수,지상철,조선행,신병철,Kim, Sung-Kyu,Jung, Soon-Hwa,Jung, Suk-Hyun,Seong, Ha-Soo,Chi, Sang-Cheol,Cho, Sun-Hang,Shin, Byung-Cheol 대한화학회 2008 대한화학회지 Vol.52 No.1
나노 또는 마이크로 크기를 가지는 구형의 약물 전달체이다. 그러나 일반적인 리포솜은 혈류 순환시 혈장 단백질과의 흡착이 일어나 안정성이 떨어지고, 세망내피계의 대식세포에 의해 옵소닌작용이 일어나 혈중에서 쉽게 소실되는 단점이 있다. 이에 본 연구에서는 모델단백질로 소혈청 알부민(BSA)을 사용하였고, BSA의 등전점보다 높은 pH를 나타내는 수용액에 용해하여 BSA가 음이온성을 갖도록 제조하였으며 이를 양이온성 리포솜 표면에 정전기적 인력에 의해 결합시켰다. 그리고 리포솜 표면에 코팅된 알부민을 60oC 이상의 온도에서 변성시켜 알부민이 코팅된 리포솜을 제조하였다. 대조 리포솜과 양이온성 리포솜의 입자크기는 104±1nm를 나타내었고, 변성된 알부민이 결합된 리포솜은 109±1nm의 입자크기를 나타내었다. 모델약물로서는 독소루비신(doxorubicin, DOX)을 사용하였고, 이온구배에 의한 리모트 로딩 방법을 사용하여 리포솜 내부에 DOX를 봉입시켰다. 혈장 내에서 리포솜의 안정성을 평가한 결과, 알부민이 결합된 리포솜은 입자크기의 변화가 관찰되지 않았고, 대조 리포솜과 양이온 리포솜에 비해 단백질 흡착이 억제되어 변성된 알부민으로 코팅된 리포솜은 혈류 내에서 장기 순환이 가능한 약물전달체로서 유용할 것이라 사료된다. are nanometer or micrometer scale vesicles that can be used as drug delivery carriers. However, plain liposomes are plagued by rapid opsonization, making their circulation time in bloodstream be shortened. In this study, model protein, bovine serum albumin (BSA)-coated liposomes were prepared by coating cationic liposomes with BSA molecules at higher pH than isoelectric point of BSA. The BSA molecules coated on the liposomal surface were denatured by thermal treatment at above 60oC. While both plain and cationic liposomes had about mean particle diameter of 1041 nm, BSA-coated cationic liposomes (BCL) had mean particle diameter of 1091 nm. Encapsulation of model drug, doxorubicin (DOX), in liposomes were carried out by using remote loading method and the loading efficiency of DOX to liposomes was about 90%. The mean particle diameter of BCL did not increase in blood plasma and adsorption of plasma protein was much less than plain or cationic liposomes. These results suggest that BCL can be used as a long-circulating liposomes in bloodstream.
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해운물류정보(海運物流情報)시스템의 활성화요인(活性化要因)이 물류성과(物流成果)에 미치는 영향(影響)에 관한 연구(硏究)
김성규,조성무,이용호,안기명,Kim, Seong-Kyu,Cho, Sung-Mou,Lee, Yong-Ho,An, Ki-Myung 한국항해항만학회 2001 한국항해학회지 Vol.25 No.2
The information technology(IT) development of telecommunication, along with the information analyzation over the world, enables the firms to process their inner and outer operations through Electronic Data Interchange (EDI) system. And the concept of logistics has become more important to the enterprises in strategic sense because it had aggrandized itself to more comprehensive and integrative concept. Also the world shipping market is more competitive than any other market. In these environment, to maintain competitive power, shipping firms process operations by Logistics Information system(LIS), And then, reduce the working processes, working time and its costs. So the LIS has become more important in developing our national logistics system and industry. Therefore, this study purposes on empirically analyzing the activation factors of shipping LIS and the relationship these, factors with logistic performances in the shipping industry. Considering environments of Shipping logistics information system, this study sets up the research model and hypothesis to examine the activation factors of shipping LIS and the relationship these factors with logistic performances. We used the field data on the 163 numbers of firms(29 overseas shipping companies and 133 forwarding Agency) to get the empirical evidence. According to the study results, The shipping LIS activation factors which the sample firms recognized as important: were top managers support, well structured communication channel, strategic plans connection and inner information analyzation level. And IS organization & human resources, IS discipline & training, software development, IS organizational alignment, database management system, information standardization, competitive advantage, financial support and government support represent partially significant. Also, the current shipping LISs main problems are expensive system cost, standardization of working processs, institutions imperfection and systems interaction defect. So these problems must be improved to activate shipping LIS.
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김성규(Kim, Seong-kyu) 충남대학교 충청문화연구소 2013 충청문화연구 Vol.11 No.-
The focus of this paper is to examine his attitude of composing poems and sense of direction shown in the first collection of poems of Hwang, Ji-woo, Birds Also Leave The World. ‘Anatomy of Criticism’, written by Northrop Frye, and his work of criticism is the material of intertextuality chosen to study and advance this paper. The combination of Frye and Hwang seems rather strange, unfamiliar and disparate like Hwang’s poems. However, I confirmed a possibility of the combination of both parties as follows: First, the gloomy reality in their literary works is described as the same image of winter. Second, although his poetry shows twisted language structure, the narrative method of Hwang can be explained by Frye’s view of irony and satire. Third, both authors pursue a liberal, classless and civilized society through either literature or criticism. Hwang, Ji-woo’s early poems reveal negative reality frankly through the narration depart from the standard pattern. It is composed in the way ingeniously twisted and disintegrated by irony and satire. This can be a series of process to move towards the utopia of spring, free from the painful awareness of reality, that is to say, Frye’s image of winter. Hwang’s poetry has great significance that he added his flexible intelligence to the rigidity of Korean popular literature in the 1980’s, studded with the poetry of work or job site, furthermore, his poetry was the indelible imprint of Korean literature that tried to straighten the distorted and heart-rending Korean history committed by a certain institution.
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김성규(金星奎) ( Kim Seong-kyu ) 한국어문교육연구회 2021 어문연구(語文硏究) Vol.49 No.1
1443년 훈민정음이 완성된 후 570여 년이 지난 현재 한글 문맹률은 매우 낮은 수준이다. 그렇다면 훈민정음이 창제된 후 전국적으로 한글이 전파되는 데 어느 정도의 시간이 걸렸을까? 이러한 의문과 관련해서는 16세기 후반에 한글이 지방에까지 광범위하게 보급되었을 것이라는 게 정설로 되어있다(안병희, 1985). 기존의 설을 따른다면 당시에 전국적으로 많은 사람이 한글을 읽을 수 있었으리라고 추정하게 된다. 그런데 1930년대의 한글 문해율이 30%에 불과하다는 조사 결과를 볼 때, 16세기 후반에 전국적으로 매우 많은 사람이 한글을 이해할 수 있었다고 하기는 어렵다. 이 논문에서는 조선왕조실록의 언문관련 자료와 문헌 간행지의 분포 등을 통해 15세기와 16세기의 한글 전파과정을 살펴보았다. 그 결과 당시에 한글을 이해할 수 있는 사람의 비율은 그리 높지 않았으며, 한글의 전파도 지역에 따라 산발적으로 일어났으리라고 추정하였다. As of 570 years after the invention of Hangeul, the illiteracy rate of Hangeul became very low in Korea. Then, how long did it take for Hangeul to spread nationwide after Hangeul was invented? Regarding this question, Ahn(1985) has stated that Hangeul had been spread to local regions already in the late 16th century, which is unlikely given that the literacy rate of Hangeul in the 1930s was only 30%. In this paper, we examine the status of Hangeul propagation in the 15th-16th century based on the Annals of Joseon Dynasty(Joseonwangjosillok) and the regional distribution of publications on that period. The results show that the literacy rate in the late 16C was not as high as expected in the literature and that Hangeul was spread rather sporadically across different regions.
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김성규 ( Seong Kyu Kim ),김소영 ( So Young Kim ) 한국문법교육학회 2013 문법 교육 Vol.19 No.-
This paper aims to analyze phonological issues of school grammar and grammar for establishing standard grammar. This work is needed because both of them has become developed differently, and differences of them are very huge. In this paper I analyze two kinds of school grammar textbooks: <munbeop> and <dokseowa munbeop>, argue that phonological knowledge and pronunciation education should be regarded as distinguishable things in education fields. Furthermore contents of school grammar should be comprised vocal language data with synchronic perspectives. Moreover I present main phonological arguments which are found among 16 korean phonology textbooks, that are composed of position of diphthong / / in phonological system and the number of monophthongs and so on.
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