졸-겔법을 이용하여 알콕사이드 전구체로부터 합성된 Polyimide-silica 혼성체의 특성

김병우,이성환,김성완,박재현,김준호,박성수,박희찬,Kim, Byoung-Woo,Lee, Sung-Hwan,Kim, Sung-Wan,Park, Jae-Hyun,Kim, Jun-Ho,Park, Seong-Soo,Park, Hee-Chan 한국세라믹학회 2002 한국세라믹학회지 Vol.39 No.11

Polyimide와 silica에 물리적 또는 화학적으로 결합된 Polyimide/silica(PI/silica) 혼성체들을 졸-겔법을 통하여 Polyamic Acid(PAA) 또는 end-capped PAA 용액에 tetraethoxysilane을 가수 분해 및 축 중합시켜서 제조하였다. PAA 용액은 dimethylacetamide 용액 내에서 pyromellitic dianhydride와 oxydianiline 단량체들을 개환 반응으로 합성하였다. End-capped PAA 용액은 PAA 용액에 3-aminopropyltriethoxysilane을 첨가하여 제조하였다. 적외선 분광기, 시차 열분석기, X-선 회절 분석기, 주사 전자현미경 및 인장 강도 시험기를 통하여 PI/silica 혼성체 시편들의 특성을 분석하였다. 혼성체 시편들의 물성은 PI와 silica간의 결합형 및 silica의 함량에 의해 영향을 받는다는 것을 확인하였다. Polyimide/silica(PI/silica) hybrid materials having physical or chemical bonds between the PI and silica network were prepared using sol-gel process through hydrolysis and polycondensation of tetraethoxysilane with the polyamic Acid(PAA) or end-capped PAA solution. PAA solution was synthesized by ring opening reaction of pyromellitic dianhydride and oxydianiline monomers in dimethyl acetamide solution. End-capped PAA solution was synthesized by the addition of 3-aminopropyltriethoxysilane in PAA solution. PI/silica hybrid samples were characterized by infrared spectroscopy, differential thermogravimetry, X-ray diffractometry, scanning electron microscopy, and tensile tester. It has been demonstrated that the properties of hybrid samples were affected by the silica content and the bond type between PI and silica.

생물정보시스템을 이용한 Local Animal BLAST Search System 구축

김병우,이근우,김효선,노승희,이윤호,김시동,전진태,이지웅,조용민,정일정,이정규,Kim, Byeong-Woo,Lee, Geun-Woo,Kim, Hyo-Seon,No, Seung-Hui,Lee, Yun-Ho,Kim, Si-Dong,Jeon, Jin-Tae,Lee, Ji-Ung,Jo, Yong-Min,Jeong, Il-Jeong,Lee, Jeong-Gyu 한국생물정보시스템생물학회 2006 Bioinformatics and Biosystems Vol.1 No.2

BLAST(Basic Local Alignment Search Tool)는 서열 데이터베이스 탐색을 위하여 가장 많이 사용되는 프로그램이다. 전체 서열간의 최적 글로벌 정렬을 수행하는 대신에 지역적 유사성이 있는 부분을 찾아 서열 짝짓기를 수행하는 특징을 갖는다. 일반적인 연구자들은 서열 상동성 검색을 위해 NCBI에 접속하여 웹 브라우저를 통해 온라인으로 BLAST를 수행하게 되는데, 이 경우 사용자 각각의 네트워크 환경이나 입력할 데이터양에 따른 검색속도의 지연 및 제한 등과 같은 여러 문제에 부딪히게 되고, 또한 보안유지가 필요한 서열 데이터의 유출 가능성이 존재한다. 그러므로 대량의 서열 데이터에 대하여 빠르고 안전하게 BLAST 상동성 검색이 가능한 Local BLAST 검색 시스템의 필요성이 증대되고 있다. 본 연구에서는 NCBI의 Genbank에서 공개된 동물의 발현 유전자 단편들(ESTs)에 대한 데이터를 이용하여 소, 돼지, 닭, 등의 경제형질과 연관된 유용 유전자만을 추출하여 이들만으로 구성된 새로운 데이터베이스를 구축하였고, 또한 이들을 사용할 수 있는 새로운 검색시스템을 개발하였다 자체 제작한 Perl script를 사용하여 필요한 데이터를 축종별로 추출 하여 새로운 DB를 구축하였으며 이 속에는 소의 경우 650,046개, 돼지의 경우 368,120개, 닭의 경우 693,005개의 발현 유전자 단편들(ESTs)이 포함된다. 또한 이들 DB 분석이 가능한 Local Animal BLAST Web 검색시스템(http://bioinfo.kohost.net)을 고성능 병렬 PC Cluster 시스템과 연동하도록 자체 구축함으로써 본 시스템이 보다 효율적인 생물정보학 연구수행이 기여할 것으로 기대된다. The Basic Local Alignment Search Tool (BLAST) is one of the most established software in bioinformatics research and it compares a query sequence against the libraries of known sequences in order to investigate sequence similarity. Expressed Sequence Tags (ESTs) are single-pass sequence reads from mRNA (or cDNA) and represent the expression for a given cDNA library and the snapshot of genes expressed in a given tissue and/or at a given developmental stage. Therefore, ESTs can be very valuable information for functional genomics and bioinformatics researches. Although major bio database (DB) websites including NCBI are providing BLAST services and EST data, local DB and search system is demanding for better performance and security issue. Here we present animal EST DBs and local BLAST search system. The animal ESTs DB in NCBI Genbank were divided by animal species using the Perl script we developed. and we also built the new extended DB search systems fur the new data (Local Animal BLAST Search System: http://bioinfo.kohost.net), which was constructed on the high-capacity PC Cluster system fur the best performance. The new local DB contains 650,046 sequences for Bos taurus(cattle), 368,120 sequences for Sus scrofa (pig), 693,005 sequences for Gallus gallus (fowl), respectively.

단계양수시험으로부터 우물수두손실 항을 이용한 단열의 고.저 투수성 평가

김병우,김형수,김건영,고용권,Kim, Byung-Woo,Kim, Hyoung-Soo,Kim, Geon-Young,Koh, Yong-Kwon 한국방사성폐기물학회 2012 방사성폐기물학회지 Vol.10 No.1

Rorabaugh(1953)에 의해 재정리된 단계양수시험 해석해 $s_w=BQ+CQ^p$는 단열암반대수층에서 비선형으로 증가하는 수위강하에 매우 적합하며, 현장에서 관측된 수위강하 값과 추정된 수위강하 사이의 제곱근 평균제곱오차(RMSE) 값이 매우 낮음을 보여주었다. 우물수두손실($CQ^p$)의 $C$ 값은 $3.689{\times}10^{-19}{\sim}5.825{\times}10^{-7}$, $P$ 값은 3.459~8.290의 범위로 산정되었으며, 지표로부터 하부심도로 내려 갈수록 양수율 증가에 따른 수위강하는 매우 크게 나타났다. 단열암반대수층에서의 우물수두손실은 다공질매질에서와 달리 단열특성(단열의 틈, 간격, 상호 연결성)에 의한 영향으로 나타나므로, 우물수두손실의 $C$ 와 $P$ 값은 단열암 반대수층의 난류구간과 고 저 투수성 단열암반의 특성을 해석하는데 매우 중요하다. 그 결과, 우물수두손실 항의 $C$ 와 $P$ 값에 대한 회귀분석 결과로부터 암반대수층의 난류구간과 수리특성의 관계가 파악되었으며, $C$ 와 $P$ 값의 관계가 단열암반대수층의 수리특성 해석에 있어 매우 유용함을 확인할 수 있었다. The equation of the step-drawdown test "$s_w=BQ+CQ^p$" written by Rorabaugh (1953) is suitable for drawdown increased non-linearly in the fractured rocks. It was found that value of root mean square error (RMSE) between observed and calculated drawdowns was very low. The calculated $C$ (well head loss coefficient) and $P$ (well head loss exponent) value of well head losses ($CQ^p$) ranged $3.689{\times}10^{-19}{\sim}5.825{\times}10^{-7}$ and 3.459~8.290, respectively. It appeared that the deeper depth in pumping well the larger drawdowns due to pumping rate increase. The well head loss in the fractured rocks, unlike that in porous media, is affected by properties of fractures (fractures of aperture, spacing, and connection) around pumping well. The $C$ and $P$ value in the well head loss is very important to interpret turbulence interval and properties of high or low permeability of fractured rock. As a result, regression analysis of $C$ and $P$ value in the well head losses identified the relationship of turbulence interval and hydraulic properties. The relationship between $C$ and $P$ value turned out very useful to interpret hydraulic properties of the fractured rocks.

하이브리드 자동차의 에너지저장장치 기술특성

김병우,Kim, Byeong-U 전력전자학회 2007 전력전자학회지 Vol.12 No.5

무형자본으로서의 R&D와 경제성장

김병우,Kim, Byeong-U 과학기술정책연구원 2006 혁신정책 Brief Vol.17 No.-

산양산삼 추출물이 지방세포의 분화에 미치는 영향

김병우,권기록,Kim, Byoung-Woo,Kwon, Ki-Rok 대한약침학회 2007 Journal of pharmacopuncture Vol.10 No.3

Objectives The purpose of this study is to investigate the effects of cultivated wild ginseng extract on primary cultured preadipocyte and adipocytes. Methods Diminish preadipocyte proliferation does primary role to reduce obesity. So, preadipocytes and adipocytes were performed on cell cultures with using Sprague-Dawley rats and treated with 0.01-1mg/ml cultivated wild ginseng extract. Result At all concentrations, cultivated wild ginseng extract wasn't show the suppress proliferation of preadipocytes significantly and failed to show effects on decomposition of adipocytes except high dosage. Conclusion Based on these findings, cultivated wild ginseng is not a suitable choice for the treatment of localized obesity.

Improvement of the Decolorization of Azo Dye by Anaerobic Sludge Bioaugmented with Desulfovibrio desulfuricans

김병우,안진영,Soo-Young Kim 한국생물공학회 2007 Biotechnology and Bioprocess Engineering Vol.12 No.3

A culture of anaerobic sludge was bioaugmented with Desulfovibrio desulfuricans for the color removal of authentic textile wastewater containing a substantial amount of sulfate, in order to improve the decolorization process. The sulfide produced by sulfate respiration of D. desulfuricans can chemically reduce azo bonds to produce a colorless metabolite in the form of aromatic amines. In the case where the culture of anaerobic sludge was bioaugmented with D. desulfuricans, the decolorization of C.I. Reactive Black 5 showed an increase of more than 14% after 48 h in comparison with that in the culture of anaerobic sludge alone. In the decolorization of authentic textile wastewater, the color removal (about 69.0%) was improved by the mixed culture of anaerobic sludge and D. desulfuricans, compared with results obtained with only anaerobic sludge as reported in our previous work, suggesting that bioaugmentation by D. desulfuricans can be useful for the decolorization of wastewater that contains complex dye compounds and sulfate.

천화산가미방(天花散加味方)이 고지방식이에 의한 당뇨병 유발 쥐의 혈청 Glucose농도와 지질구성에 미치는 영향

김병우,Kim Byoung-Woo 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.2

Effects of Cheunhwasangamibang on serum glucose and lipid composition were investigated in high fat diet induced diabetic rat. Plasma glucose and free fatty acids concentration showed a high reduction in Cheunhwasangamibang groups compared to those of control group and these values decreased to increasing Cheunhwasangamibang concentration. Plasma ${\beta}$-lipoprotein and triglyceride concentration showed a low values in Cheunhwasangamibang groups, however these values showed no significantly different in 4 ml and 6 ml treatment groups. Total cholesterol concentration showed no significantly different in control group and 2 ml Cheunhwasangamibang group, however these values in 4 ml and 6 ml treatment groups showed a reduction compared to those of control group. Plasma LDL-cholesterol concentration showed a reduction in Cheunhwasangamibang group and HDL-cholesterol showed no significantly different in all treatment groups.

영상기반의 해상 무인항공기 위치결정 방법

김병우,홍순헌(Hong, Soonheon),김태우(Kim, Taewoo),백승일(Baek, Seungil) 대한토목학회 2017 대한토목학회 학술대회 Vol.2017 No.10

자동차 HUD 표시장치의 인식특성에 관한 연구

김병우,조현덕,이영석,Kim, Byeong-Woo,Cho, Hyun-Duck,Lee, Young-Suk 한국반도체디스플레이기술학회 2008 반도체디스플레이기술학회지 Vol.7 No.3

The Paper presents some potential new uses for Head-Up Displays (HUDs) in vehicular applications, where the information conveyed to the driver goes well beyond the content of today's production HUDs. Such information potentially related to the use of cellular telephones, navigation systems, vehicle to roadside communications systems, and many others. Improvements in flat panel display technologies are enabling the presentation of larger, more reconfigurable, more daylight-viewable HUD images. In addition, A Formal test and evaluation is proposed to ensure that new information displays support the driver tasks. The above developments suggest increased future opportunities for HUDs to present useful information in an as-needed, eyes-on-the-road manner.