곡면에 부착 가능한 GPS/GLONASS 마이크로스트립 능동 안테나

김미숙,손석보,주한기,배준성,김준오,Kim, Mi-Suk,Son, Seok-Bo,Joo, Hahn-Kie,Bae, Joon-Sung,Kim, Joon-O 한국군사과학기술학회 2011 한국군사과학기술학회지 Vol.14 No.1

In this paper, dual-feed circularly polarized microstrip patch antenna for GPS L1, GPS L2, GLONASS L1 signal was fabricated by using stacked patch. It was fed by dual coaxial probe on the patch at 50ohm impedance, and was simulated to resonate at GPS L1, GPS L2, GLONASS L1. To realize characteristics of right hand circular polarization using dual-feed stacked patch antenna and hybrid coupler for $90^{\circ}$ phase difference. Output of hybrid coupler was contacted input of Low Noise Amplifier(LNA). The LNA using dual band pass filter was designed and fabricated. The measured results of the implemented antenna is VSWR < 1.5 : 1 and the gain of 32dB(Zenith) over at GPS L1, L2, GLONASS L1.

과학영재교육의 추진과 현안

김미숙,Kim, Mi-Suk 한국과학기술단체총연합회 2007 과학과 기술 Vol.40 No.5

사람의 신경교종 세포주에서 아데노바이러스 벡터를 이용한 p16/INK4a 유전자 전달에 의한 종양성장 억제

김미숙,권희충,강희석,박인철,이창훈,김창민,이춘택,홍석일,이승훈,Kim, Mi-Suk,Kwon, Hee-Chung,Kang, Hee-Seog,Park, In-Chul,Rhee, Chang-Hun,Kim, Chang-Min,Lee, Choon-Taek,Hong, Seok-Il,Lee, Seung-Hoon 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.4

Objective : p16/INK4a, a kind of tumor suppressor genes, encodes a specific inhibitor of the cyclin D-dependent kinases CDK4 and CDK6. This prevents the association of CDK4 with cyclin D1, and subsequently inhibits phosphorylation of retinoblastoma tumor suppressor protein(pRb), thus preventing exit from the G1 phase. According to previous reports, over 50% of glioma tissue and 80% of glioma cell lines have been demonstrated inactivation of p16/INK4a gene. The purpose of this study was to determine whether recombinant adenovirus-p16 virus is a suitable candidate for gene replacement therapy in cases of glioma. Methods : Three human glioma cell lines(U251MG, U87MG and U373MG) that express mutant p16 protein were used. Replication-deficient adenovirus was utilized as an expression vector to transfer exogenous p16 cDNA into the cells ; control cells were infected with the Ad-${\beta}$-gal expressing ${\beta}$-galactosidase. To monitor gene transfer and the expression of exogenous genes, we used Western Blotting analysis. Flow cytometry studies of cellular DNA content were performed to determine the cell cycle phenotype of the glioma cells before and after treatment. Results : We showed here that restoration of p16/INK4a expression in p16 negative U87MG, U251MG and partially deleted U373MG by Ad-CMV-p16 induced growth suppression in vitro. Flow cytometric study revealed that Ad-CMV-p16 infected U87MG cells were arrested during the G0-G1 phase of the cell cycle. Expression of p16 transferred by Ad-CMV-p16 in glioma cells was highly efficient and maintained for more than seven days. Conclusions : Our results suggest that Ad-CMV-p16 gene therapy strategy is potentially useful and warrants further clinical investigation for the treatment of gliomas.

중국과 베트남 초기 경제특구와 비교를 통한 북한 경제특구 평가

김미숙,최대식,김두환,Kim, Mi-Suk,Choi, Dae-Sik,Kim, Doo-Whan 한국토지주택공사 토지주택연구원 2016 LHI journal of land, housing, and urban affairs Vol.7 No.4

1990년대 초반 나선특구 지정을 시작으로 추진한 북한의 경제특구 개발전략이 아직까지 이렇다 할 성과를 내고 있지 못한 이유는 무엇인가? 북한은 중국 베트남의 '점진적' 개혁 개방 또는 경제개발에 성공할 수 있을 것인가? 그러기 위한 조건은 무엇인가? 이 연구는 중국, 베트남, 북한의 경제특구 사례를 '맥락과 목적', '개발 관리제도', '입지와 인프라 공급'의 범주에서 비교 평가하였다. 사례비교 결과 북한의 경제특구 전략은 먼저 역사적 맥락과 추진 목적 측면에서 중국 베트남과 차이를 보이고 있다. 중국, 베트남과 마찬가지로 외자유치를 목적으로 하였지만, 북한의 경제특구는 '경제개혁(또는 시장도입) 없는 개방'이어서 중국과 베트남의 경제특구가 가지는 '국가경제 전반의 개혁을 목표로 한 테스트베드로서 개방'과 그 성격을 달리한다. 이러한 차이가 소극적인 분권화 수준과 입지선택으로 귀결되었으며, 상대적으로 토지제도와 세제혜택 등에서 중국, 베트남과 비교해 불리하지 않았음에도 불구하고 북한 경제특구 전략이 성과를 내지 못하였다. 사례비교를 통해 도출한 시사점은 다음과 같다. 첫째, 북한의 경제특구 전략이 성공하기 위해서는 먼저 포괄적이고 장기적인 경제개발 계획 하에 경제특구 전략을 배치하여야 한다. 그것의 실내용은 외부 경제체제와 호환되는 '신뢰할 수 있는 시장경제'의 확대가 되어야 한다. 이를 위해 북한은 정치 외교적 차원에서 체제안정을 확보해야 할 것이며, 역으로 그것이 외부에서 북한의 개방과 협력을 이끌어 내기 위한 조건이 될 것이다. 둘째, 개발관리체계에서 분권화와 입지선택에서 더 과감한 시도를 해야 한다. 대도시 또는 외부와 연계가 용이한 지역의 노동력과 인프라를 활용하는 전략, 분권화를 통해 창조적인 제도 실험이 가능하게 하는 시도가 필요하다. 셋째, 인프라건설자본 부족을 해결하기 위해 BOT 방식 등을 적극 도입할 필요가 있다. North Korea(NK) has designated the special economic zones(SEZs) since the first one in Rason. But, why have the SEZs in NK still not been developed successfully? This study comparatively evaluated the SEZs in China, Vietnam and NK, with respect to 'context/purpose', 'development/management system', and 'location/infrastructure.' NK's strategies for the SEZs were different from those of China and Vietnam in terms of historical context and development purpose. China and Vietnam chose the market opening policy aiming to reform their national economy, while NK tried the opening policy without the economic reform. This difference made NK's decentralization and location strategies marginal. In spite of the positive land system and tax benefit of NK, the strategies couldn't make a successful result. The implications of this comparative study are as follows. Firstly, NK needs to establish a strategy for the SEZs in accord with the comprehensive and long-term plan for economic development and 'trustworthy and substantial market-systems' being compatible with outside world. For that, NK has to secure the regime stability in political and diplomatic dimensions. Secondly, NK has to carry out policies of decentralization and location of the SEZs more positively. Thirdly, in order to solve the problem related to lack of infrastructure capital, NK needs to utilize a BOT scheme.

식이섬유 수준이 유색육용계의 육질에 미치는 영향

김미숙,문윤희,임사비나,김대진,Kim, Mi-Suk,Moon, Yoon-Hee,Lim, Sabina,Kim, Dae-Jin 한국생명과학회 1997 생명과학회지 Vol.7 No.4

This study was conducted to investigate the effect of dietary fiber(DF) levels on the meat quality in colored broiler. Colored broiler were fed on containing corn-soy basal diet(DF 5%) and high level(DF 6,7 and 8%) of dietary fiber diets for 7 weeks. Dietary fiber level of diet was make up by adding some alffalfa meal. Colored broiler meats were stored at 3$\circ$ for 24hr after skaughter, and used to analyze physico-chemical properties. Proximate component, pH, shear force value, myofibril fragmentation index, water holding capacity, cooking loss, protein extractability, fatty acid composition, Hunter's L, a value and palatability of cooked meat were not significantly affected by dietary fiber levels, whereas the Hunter's value of meat was significantly affected bty dietary fiber levels for the final period of feeding. Crude protein content, myofibril fragmentation index, water holding capacity, protein extractability and Hunter's b value of breast meat's were higher than thigh meat's, but crude fat content, pH, shear force value, cooking loss, palmitoleic acid, linolenic acid, and Hunter's a value were lower, regardless of dietary fiber level.

토지정책 추진체계 변화 연구

김미숙,윤정란,박상학,Kim, Mi-Suk,Yun, Jeong-Ran,Park, Sang-Hak 한국토지주택공사 토지주택연구원 2011 LHI journal of land, housing, and urban affairs Vol.2 No.4

본 연구는 토지이용을 둘러싼 정책 환경변화에 따라 우리나라의 토지정책 추진체계의 변화가 필요한 시점에서 지금까지 우리나라 토지정책추진체계를 분석하고 향후 방향을 제시하고자 하였다. 이를 위해 1960년대 이후부터 최근까지 시대별 유형별로 우리나라 토지정책의 변화에 따라 토지정책의 추진체계가 어떻게 변화하였는지 추이를 살펴보았다. 분석결과 우리나라 토지정책 추진체계의 특징은 첫째, 1960년대 이래 최근까지 대규모 및 신속한 개발을 뒷받침하는 방향으로 정립되어 왔다. 둘째, 경제개발이후 우리나라의 토지정책 추진체계는 영역별로 전문화를 이루어왔지만, 개발과 보전이 조화를 이룰 수 있도록 통합적 관리를 위한 조직체계는 부족했다. 셋째, 토지이용관련 중앙정부의 권한을 지방에 이양 및 토지개발에서 민간 및 주민참여를 확대해왔다. 넷째, 토지와 관련된 정보 관리 목적이 조세징수에서 점차 토지시장 관리, 계획적 토지이용이라는 측면으로 강조점이 변화되어가고 있는데, 계획적 이용과 관리에는 부합하지 못하고 있다. 본 연구의 시사점 및 향후 추진체계의 개편 방향은 첫째, 토지이용을 둘러싼 여건변화 및 외국의 사례를 볼 때 토지수요가 안정화될 가능성이 높으므로, 대규모 개발 중심의 추진체계에서 탈피할 필요가 있다. 둘째, 향후 인구감소 및 기후변화 등으로 토지자원의 효율적 이용 및 보전적 토지이용이 중요해질 것이므로 이에 대응할 수 있는 추진체계가 필요하다. 셋째, 다양한 주체의 참여 확대와 실질적인 역할을 할 수 있는 방안이 필요하다. 넷째, 토지정보관리를 통합적 체계적으로 구축할 수 있는 추진체계 정비가 필요가 있다. The goal of this research is to suggest the desirable directions of the land policies implement system based on analysis of existing those of Korea with the paradigm shift of land policies. We classify the land policies into land ownership, land use, land development and land management ones, and then analyze their implement system characteristics. The results are follows : firstly, the land policies implement systems have been set to large scale and rapid development. Secondly, although the systems have been specialized by their areas, the comprehensive manage systems for the harmony between development and conservation are lacking. Thirdly, the parts of the central government powers related to land use has been hand covered to local governments. And the participations of residences private companies have enlarged in the land development. Fourthly, the purposes of the information management on land use have been changed from tax collection into planned land use, but the information management has not met the need of planned land use. This study shows that firstly, the implement system focusing on large development projects might be no longer effective because of high possibility of the property prices stabilization, so moderately small ones must be found. Secondly, the system cope with the climate change and to realize the efficient utility of land is needed. Thirdly, it is necessary to take the actual measures to participate a variety of subjects. Fourthly, the system modification of the land information manage system as land policies infra is also needed to establish integral land policies.

낙동강 부영양화와 수질환경요인의 통계적 분석

김미숙,정영륜,서의훈,송원섭,Kim, Mi-Suk,Chung, Young-Ryun,Suh, Euy-Hoon,Song, Won-Sup 한국조류학회(藻類) 2002 ALGAE Vol.17 No.2

Influences of vrious environmental factors on the eutrophication of Nakdong River were analyzed statistically using water samples collected from 1 January, 1999, to 30 September, 2001 at Namji area. The relationships between the concentration of chlorophyll α (eutrophication index) and environmental factors and were analyzed to develop a statistical model which can predict the status of eutrophication. The concentation of chlorophyll α ranged from 66.2 mg · $m^{-3}$ to 70.8 mg · $m^{-3}$ during dry winter season and the average concentration during this study period was 35.5 mg · $m^{-3}$ Namji area of Nakdong River was in the hypereutrohic stage in terms of water quality. Stephanodiscus sp. and Aulacoseria granulata var. angustissima were dominant species during the witnter to spring time and summer to autumn period, respectively. Based on the correlation analysis and the analysis of variance between chlorophyll α concentration and environmental factors, significantly high positive relationships were found in the order of BOD> pH> COD > KMnO₄ consumption > DO > conductivity > alkalinity. In contrast to these factors, significantly negrative relationships were found as in the order of $PO₄^{3-}-P$ >water level>the rate of Namgang-dam discharge > NH₃-N> the rate of Andong-dam discharge> the rate of Hapchoen-dam discharge. Based on the factors analysis of environmental factors on the concentration of chlorophyll α, we obtained five factors as follows. The first factor included water level, pH, turbiditiy, conductivity, alkalinity and the rate of Namgang-dam discharge. The second factor included water temperature DO, NH₄+-N, NO₃- -N. The third factor included KMnO₄ consumption COD and BOD. The fourth factor included the rate of Andong-dam discharge, the rate of Hapcheon-dam discharge, and the rate of Imha-dam discharge. The final factor included T-N T-P and $PO₄^{3-}-P$ > concentration. We derived two statistica models that can predict the occurrence of eutrophication based on the factors by factor analysis, using regression analysis. The first model is the stepwise regression model whose independent variables are the factors produced by factor analysis : chl α (mg · $m^{-3}$ = 42.923+(18.637 factor 3) + (-17.147 factor 1) + (-12.095 factor 5) + (-4.828 factor 4). The second model is the alternative stepwise regression model whose independent variables are the sums of the standardized main component variables:chl α (mg · $m^{-3}$ = 37.295+(7.326 Zfactor 3) + (-2.704 Zfactor 1)+(-2.341 Zfactor 5).

새로운 정공차폐 층 (Hole blocking layer)으로 DCJTB 도핑된 24MeSAlq를 이용한 백색유기발광다이오드

김미숙,임종태,염근영,Kim, Mi-Suk,Lim, Jong-Tae,Yeom, Geun-Young 한국재료학회 2006 한국재료학회지 Vol.16 No.4

To obtain balanced white-emission and high efficiency of the organic light-emitting diodes (OLEDs), a deep blue emitter made of N,N'-diphenyl-N,N'-bis(1-naphthyl)- (1,1'-biphenyl)-4,4'-diamine (NPB) emitter and a new red emitter made of the Bis(2,4 -dimethyl-8-quinolinolato)(triphenylsilanolato)aluminum(III) (24MeSAlq) doped with red fluorescent 4-(dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H -pyran (DCJTB) were used and the device was tuned by varying the thickness of the DCJTB-doped 24MeSAlq and $Alq_3$. For the white OLED with 10 nm thickness DCJTB (0.5%) doped 24MeSAlq and 45 nm thick $Alq_3$, the maximum luminance of about 29,700 $Cd/m^2$ could be obtained at 14.8 V. Also, Commission Internationale d'Eclairage (CIE) chromaticity coordinates of (0.32, 0.28) at about 100 $Cd/m^2$, which is very close to white light equi-energy point (0.33, 0.33), could be obtained.

암 치료를 위한 보론 중성자 포획치료의 현황

김미숙,Kim, Mi-Suk 한국동위원소협회 1997 동위원소회보 Vol.12 No.4

한국 영재교육, 어디까지 왔으며 무엇이 문제인가- 영재교육 도입 5년 양적.질적성과 긍정적

김미숙,Kim, Mi-Suk 한국과학기술단체총연합회 2008 과학과 기술 Vol.41 No.5