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고주파유도결합에 의해 여기된 물플라즈마로부터 수소생산에서 메탄가스 첨가효과
김대운,정용호,추원일,장수욱,이봉주,김영호,이승헌,권성구,Kim, Dae-Woon,Jung, Yong-Ho,Choo, Won-Il,Jang, Soo-Ouk,Lee, Bong-Ju,Kim, Young-Ho,Lee, Seung-Heun,Kwon, Sung-Ku 한국전기전자재료학회 2009 전기전자재료학회논문지 Vol.22 No.5
Hydrogen was produced from water plasma excited in high frequency (HF) inductively coupled tubular reactor. Mass spectrometry was used to monitor gas phase species at various process conditions, Water dissociation rate depend on the process parameters such as ICP power, $H_{2}O$ flow-rate and process pressure, Water dissociation percent in ICP reactor decrease with increase of chamber pressure, while increase with increase of ICP power and $H_{2}O$ flow rate. The effect of $CH_4$ gas addition to a water plasma on the hydrogen production has been studied in a HF ICP tubular reactor. The main roles of $CH_4$ additive gas in $H_{2}O$ plasma are to react with 0 radical for forming $CO_x$ and CHO and resulting additional $H_2$ production. Furthermore, $CH_4$ additives in $H_{2}O$ plasma is to suppress reverse-reaction by scavenging 0 radical. But, process optimization is needed because $CH_4$ addition has some negative effects such as cost increase and $CO_x$ emission.
사람의 자궁 내막 조직내에서 Phosphodiesterase IV Inhibitor에 의한 IL-12의 조절 및 이에 따른 Th-1, Th-2 cytokine 분비 양상의 변화
박원일 ( Park Won Il ),김은경 ( Kim Eun Gyeong ),고덕성 ( Go Deog Seong ),홍서유 ( Hong Seo Yu ),나중열 ( Na Jung Yeol ),김대운 ( Kim Dae Un ),신정환 ( Sin Jeong Hwan ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.8
목적 : 사람의 초기 임신 과정에서 phosphodiesterase type IV inhibitor인 rolipram이 탈락막내 IL-12를 억제하고 이에 따라 Th-1 계열의 cytokine이 감소하고 Th-2 cytokine이 증가하는지를 규명하는 것이 목적이다. 연구 방법 : 임신 12주 이전에 계류 유산으로 진단받은 10명과 정상임신에서 임신 중절 수술을 시행받은 10명에서 자궁 소파술을 통하여 탈락막 조직을 획득한 후 조직을 rolipram으로 Objective : To assess the capability of phosphodiesterase type IV inhibitor (rolipram) to suppress IL-12 in human decidua and the subsequent changes of Th-2 cytokine (IL-10) and Th-1 cytokine (TNF-α). Methods : Decidual tissues of 10 first-trimester pregn
조기 및 후기 산후출혈의 혈관조영술 소견 및 초선택적 동맥색전술의 치료 효과
김재령 ( Jae Ryoung Kim ),조영권 ( Young Kwon Cho ),김혜민 ( Hye Min Kim ),최은주 ( Eun Joo Choi ),김대운 ( Dae Woon Kim ),서용수 ( Yong Soo Seo ),이진용 ( Jin Yong Lee ),박원일 ( Won Il Park ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.1
목적: 자궁동맥색전술은 산후출혈의 치료에 이미 보편적으로 이용되고 있다. 그러나 조기 및 후기 산후출혈에서 동맥조영술상의 차이가 있는지는 아직 잘 알려지지 않았다. 본 연구의 목적은 조기 및 후기 산후출혈에서 동맥조영술상의 차이가 있는지를 규명하고 자궁동맥색전술의 산후출혈의 치료효과를 확인하는 것이다. 연구 방법: 산후출혈로 동맥색전술을 시행받은 12명의 환자의 의무기록과 동맥조영술 사진을 후향적으로 분석하였다. 출혈시간, 분만방법, 치료효과, 동맥조영술 소견을 일차적 분석항목으로 정하였다. 결과: 12명 중 11명에서 초선택적 색전술로 효과적 지혈이 가능했다. 1명은 양수색전증과 범발성 혈관내응고로 사망하였다. 혈관조영술상 조기 산후출혈에서 자궁적출술을 받지 않은 5명 모두에서 자궁 크기가 커져있는 자궁이완증의 소견이 관찰되었고 후기 산후출혈에서는 5예 모두에서 거짓동맥류가 확인되었다. 결론: 초선택적 색전술은 효과적인 산후출혈의 치료법이다. 후기 산후출혈의 경우는 거짓동맥류가 중요한 원인으로 생각된다. Objective: Treatment of postpartum bleeding with uterine artery embolization has been well-described so far. However, angiographic differences between early and late postpartum bleeding has not been elucidated. The purpose of this study was to evaluate angiographic differences between early and late postpartum bleeding and therapeutic effect of superselective embolization. Methods: Medical records and angiographic images of 12 patients (7 early and 5 late) with postpartum bleeding were evaluated. Timing of bleeding, mode of delivery, angiographic findings and treatment outcome were primary variables evaluated. Results: Among 12 patients, 11 patients had been successfully treated with superselective embolization. One patient with amniotic fluid embolism and disseminated intravascular coagulation had expired. Among the early postpartum bleeding, uterine atony was found in every patients except post-cesarean hysterectomy cases. Pseudoaneurysm of uterine artery was found in all patients with late postpartum bleeding. Conclusion: Superselective embolization is an effective method to control postpartum bleeding. Pseudoaneurysm of uterine artery is a main cause of late postpartum bleeding.
임신 중기 triple marker screenig test의 다운 증후군의 예측성에 대한 고찰
한경철(Kyoung Chul Han),김대운(Dae Woon Kim),정수미(Su Mi Jeong),양원규(Won Kyu Yang),박철범(Chul Beom Park),신봉규(Bong Kyu Shin),신정환(Jeong Hwan Shin),홍서유(Seo You Hong) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.9
본 연구에서는 임신 중기에 행해지는 산전 검진인 triple marker screening test의 다운 증후군 예측성에 대한 신뢰도에 대해 고찰을 하고자 하였으며 구체적으로, 첫째, 선별 검사상 양성인 산모의 경우 향후 그 임신의 결과를 분석하였고, 둘째, 분만된 신생아에서 염색체 이상을 보인 경우 그 신생아의 임신시에 시행한 선별검사와의 상관관계를 비교 분석하였다. 검사를 시행한 산모 3700명중 67명(1.81%)이 검사 양성, 67명중 1명이 실제로 다운 증후군 이었으며, 검사 음성은 3633명(98.18%)이었고 이중에서 4 명이 염색체 이상으로 분만되었으며, 4명중 다운 증후군은 2명이었다. 분석 결과 본원에서 시행한 다중 혈청 지표 선별 검사의 다운 증후군에 대한 민감도는 33.3% 특이도는 98.2%로 문헌에서 보고 되고 있는 결과와 비교 해볼 때 상당히 낮은 민감도를 나타냈다. 따라서 이에 대한 원인에 대해 고찰해보았다. Objective: To assess the reliability of triple marker screening test in midtrimester pregnancy for fetal Down syndrome. Methods: From October 1, 1996 to May 31, 1998 at Nowon Eulji Hospital, 3700 Pregnant women underwent serum tiple marker screening for Down syndrome during 15-20weeks of gestational age. The results of serum triple marker screenig tests for Down syndrome and the outcomes of pregnancies were retrospectively assesed. Results: Sixty seven of 3700 cases(1.81%) were positive in screening test, and 3633(98.18%) cases were negative. Among 67 cases of positive screening test , 1 case(1.49%) was diagnosed as Down syndrome. Among 3633 cases of negative screening test, 4 cases(0.1%) were diagnosed as chromosomal abnormalies postnatally. Two of these 4 cases of chromosomal abnormalies were Down syndrome. Conclusion: With this results, sensitivity of triple marker screeing test for Down syndrome is very low as 33.3%. In order to increase the sensitivity, some compensatory adjustment is required in triple marker screening test.
조산 예측인자로서 자궁경관 분비물내 인슐린 유사 성장인자 결합 단백질 - 1
신봉규(Bong Kwy Shine),김상준(Sang Jun Kim),박원일(Won Il Park),김주오(Joo Oh Kim),김대운(Dae Woon Kim),홍서유(Seo You Hong),윤혜선(Hye Sun Yoon) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.12
N/A Objective : The phosphorylated isoforms of insulin-like growth factor-binding protein-1 (IGFBP-1) were produced by the decidua. The aim of this study was to evaluate whether the presence of phosphorylated IGFBP-1 (phIGFBP-1) in cervical secretions of pregnant women with preterm uterine contractions can predict an increased risk of preterm delivery and infectious complications. Method : The prospective study of 32 pregnant women who admitted under the diagnosis of preterm labor with intact membrane at gestational age of 24+0 to 36+0 weeks. Phsphorylated IGFBP-1 was qualitatively assayed using immunochromatography in cervical swab samples at the time of admission. The interval between the test and delivery, gestational age, duration of tocolysis, birth weight, CRP, ESR and the presence of neonatal infection were compared between positive and negative groups. Results : There was no differnce in age, obstetric histories and gestational age and Bishop score at the time of admission between two groups. Eight pregnacies out of 13 positive group and two pregnacies out of 19 negative group resulted in preterm birth. The sensitivity and specificity of the phIGFBP-1 test to predict preterm birth were 80.0% and 77.3%, respectively. The mean getational age and interval between the test and delivery were 38.36 weeks and 45.0 days and 35.78 weeks and 35.46 days in negative and positive group respectively. The birth weight of the babies was significantly higher in negative group. The duration of tocolysis was longer in positive group with marginal statistical significance. The CRP, ESR and WBC count were not different. One postpartum sepsis, one neonatal death and one necrotizing enterocolitis were complicated in positive group. Conclusion : The presence of phIGFBP-1 is an usful marker to predict preterm birth in case of regular uterine contraction with intact fetal membranes
자궁강내 인공수정으로 임신된 쌍태아 중 한 명에서 발견된 치사성 이형증
박태웅 ( Tae Woung Park ),박원일 ( Won Il Park ),김대운 ( Dae Woon Kim ),신영진 ( Young Jin Shin ),김은경 ( Eun Kyung Kim ) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.11
Twin gestations complicated by a single anomalus fetus present difficulties in obstetric management. It is unclear how the presence of a congenital anomaly in one twin affects its normal sibling. Parents may elect for obstetric management option such as e