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위식도 역류성질환 관련 인후두역류(Laryngopharyngeal Refulx : LPR)증상을 호소하는 환자에서의 라니티딘의 치료효과 연구
장혁순,고윤우,김광현,김민식,김상윤,김영모,도남용,백정환,안순현,엄재욱,양훈식,우훈영,이형석,Chang, H.S.,Ko, Y.W.,Kim, K.H.,Kim, Y.M.,Kim, S.Y.,Kim, Y.M.,Do, M.Y.,Beak, C.H.,Ahn, S.H.,Eom, J.W.,Yang, H.S.,Woo, H.Y.,Lee, H.S. 대한기관식도과학회 2004 大韓氣管食道科學會誌 Vol.10 No.2
Background : LPRD(Laryngopharyngeal reflux disease) gives rise to inflammatory change in the pharyngolaryngeal tissue with various otolaryngologic symptoms. Ranitidine, histamine H2receptor antagonists, are currently used as therapeutic medications. However, the efficacy of Ranitidine on LPRD has not been proven yet. Objectives : We intended to analyze the efficacy of the Ranitidine on LPRD. Materials :md Methods : In 20 multicenter, 607 patients with LPR(laryngopharyngeal reflux) symptom were observed to evaluate their symptoms and laryngoscopic findings after 4 weeks, 8 weeks, and 12 weeks of treatment of Ranitidine. Results : The symptom of LPR including globus sensation, sore throat hoarseness, regurgitatioin are improved after 4 weeks $86.2\%,\;8 weeks\;91.5\%,\;12 weeks\;92.9\%$ of Ranitidine treatment and improved after 4 weeks $91.5\%,\;8 weeks\;94.5\%,\;12 weeks\; 97.2\%$ of Ranitidine combined with prokinetics. The rates of sore throat, chronic cough, globus sensation improvement at 8 weeks after treatment are $26.7\%,\;16.7\%,\;16\%$. Conclusion : In patient with LPR, Ranitidine treatment reduces LPR symptoms very effectively.
Methionine 급여수준이 돼지의 정액성상에 미치는 영향
김광현(K . H . Kim),문승주(S . J . Moon) 한국축산학회 1990 한국축산학회지 Vol.32 No.12
This study was carried out to investigated the influence of methionine addition on semen quality of boar, 12 crossbred boars were allotted to 4 treatments; NRC methionine requirement(A), additions of 7g(B), 14g(C), and 21g (D) to NRC methionine requirement. The results obtained are summarized as follows; 1. Semen volume and total sperm number of the treatment B and C were increased significantly(p $lt;0.05) as compared with treatment A and D. But sperm number mortility index and abnormal sperm percent were not different from treatments. 2. The amino acid contents of boar semen plasma were not different from treatments. However, the treatment A showed slightly lower cystine and methionine contents than other treatments.
저단백질사료 급여시 육성돈의 Methionine 요구량에 대한 연구
김광현(K . H . Kim),곽종형(C . H . Kwack),김용식(Y . S . Kim),전우복(W . B . Chun),이상진(S . J . Lee) 한국축산학회 1990 한국축산학회지 Vol.32 No.12
This study was conducted to determine the optimumn level of DL-methionine for pro-finishing piglets fed 12% CP corn-soy diet fortified with 0.24% L-lysine and 0.06%, L-threonine. Onehundred and twenty growing pigs(L × W × D :34.4kg BW) were randomly allotted to 4 supplemental levels of DL-methionine treatments(0, 0.035, 0.07 and 0.105%) for 36 days feeding trial Each treatment consisted of 3 replicates and 10 pigs per replicate, respectively. A metabolic trial was conducted with 12 pigs for 5 days after the feeding trial. Results obtained were summarized as follows: l. Although there was no statistical differences among treatments, the average daily weight gain in 0.07% treatment and feed intake in basal diet were a little higher than the other treatments. However, there was a significant difference(p$lt;.05) between 0.07% and other groups in feed conversion. 2. Although there was no significant differences among treatments, the highest values of crude protein digestibility, TDN and nitrogen retention were obtained with the 0.07% treatment. However. the methionine availability value(88.82%) of 0.07% treatment was significantly(p$lt;.05) higher than those of the other treatments. 3. The free S-containing amino acid level of plasma tended to increased as dietary level of methionine increased. However, the plasma urea-N level was the lowest in 0.07% treatment. 4. The total non-sulfur free essential amino acid level of plasma was lowest in 0.07% treatment and tended to increase as the methionine level increased to 0.105%. It could be concluded that the optimum level of DL-methionine supplementation for growing piglets fed 12% CP corn-soy diet is 0.07%, resulting in 0.45% S-containing amino acids in the diet.
Methionine 의 첨가수준이 돼지의 성장 및 도체 생산에 미치는 영향
김광현(K . H . Kim),문승주(S . J . Moon) 한국축산학회 1991 한국축산학회지 Vol.33 No.4
This study was conducted to determine the effects of DL-methionine addition level on the growth of swine and pork carcass quality. One hundred and twenty weanling pigs (L × W × D; 9.2㎏ BW) were randomly allotted to 4 supplemental levels of DL-methionine treatments (0, 0.035, 0.07 and 0.105%) in a 144-day feeding trial. Each treatment consisted of 3 replicates and 10 pigs per replicate, respectively. After the feeding trial. fourty eight pigs were slaughtered for carcass quality evaluation. Results obtained were summarized as follows ; l. There was significant difference(p$lt;.05) among treatments, the best values of daily weight gain and feed conversion were recorded with the 0.07% treatment. Although there were no statistical differences among treatments. daily feed intake was better in 0.07% treatment than the other treatments. 2. Carcass quality was not significantly affected by methionine levels.
저단백질사료 급여시 비육돈의 Methionine 요구량에 대한 연구
김광현(K . H . Kim),곽종형(C . H . Kwack) 한국축산학회 1990 한국축산학회지 Vol.32 No.12
This study was conducted to determine the optimum level of DL-methionine for finishing pigs fed 10% CP corn-soy diet fortified with 0.30% L-lysine and 0.09% L-threonine. One hundred and twenty finishing pigs (L × W × D: 56.6kg BW) were randomly allotted to 4 supplemental levels of DL-methionine treatments(0, 0.035, 0.07 and 0.105%) for 63 days per replicate. respectively. A metabolic trial was conducted with 12 pigs for 5 days after the feeding trial. Results obtained were summarized as follows; 1. There was significant difference(p$lt;.05) among treatments, the best value of daily weight gain and feed conversion were recorded with the 0.07% treatment. Daily feed intake were better in 0.035% treatment than the other treatments. 2. Although there was no significant differences among treatments, the highest values of crude protein digestibility, TDN and nitrogen retention were recorded with the 0.07% treatment. However, the methionine availability value(89.28%) of 0.07% treatment was significantly(p$lt;.05) higher than those of the other treatments. 3. The free S-containing amino acid level of plasma tended to increase as dietary level of methionine increased. However, the plasma urea-N level was the lowest in 0.07% treatment. 4. The total non-sulfar free essential amino acid level of plasma was lowest in 0.07% treatment and showed tendency to increase as the methionine level increased to 0.105%. It could be concluded that the optimum level of DL-methionine supplementation for finishing pigs fed 10% CP corn soy diet is 0.07%, resulting in 0.40% S-containing amino acids in the diet.