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주입 전하량의 실시간 제어에 의한 PPLN 제작 및 분극반전 과정 분석
권재영,김현덕,송재원,Kwon, Jai-Young,Kim, Hyun-Deok,Song, Jae-Won 한국광학회 2006 한국광학회지 Vol.17 No.3
효율적인 PPLN 제작을 위하여 DC 전계를 인가하면서 $LiNbO_3$에 인가되는 전압 및 전류를 실시간으로 측정할 수 있는 실험 장치를 제안하였다. 제안된 실험 장치를 사용함으로써 PPLN의 분극반전에 필요한 충분한 전하량을 공급하기 위한 전계인가시간을 수초 단위로 증가시킬 수 있어 $LiNbO_3$에 주입되는 전하량의 조절을 용이하게 할 수 있었다. 또한 PPLN의 분극반전 과정을 단계별로 분류하고 각 단계별 실험결과를 바탕으로 분석함으로써 최적의 PPLN 제작조건을 구할 수 있었다. We proposed a PPLN fabrication setup that measures the voltage and current applied to $LiNbO_3$ in real time during application of a DC electric field. Because the duration for transferring a sufficient electron charge to $LiNbO_3$ increases, we are able to control the electron charge flow transferred to $LiNbO_3$ efficiently. We divided the domain inversion process of PPLN into 5 states: Nucleation (state 1), Spread of the domain inversion region under the electrode(state 2), Accumulation of the electron charge at the insulator/$LiNbO_3$ interface(state 3), Domain inversion under the insulator layer after breakdown(state 4), and Lowering the electric field applied to $LiNbO_3$ (state 5). We have found that the Threshold Point is essential for the domain inversion and that the domain inversion process must be stopped within state 3 for the optimum PPLN. Using these results, we could fabricate a stable and reproducible PPLN efficiently.
김인세,권재영,백승완,정규섭,Kim, Inn-Se,Kwon, Jae-Young,Baik, Seong-Wan,Chung, Kyoo-Sub The Korean Journal of Pain 1993 The Korean Journal of Pain Vol.6 No.2
세포막에서 마취제의 작용점을 규명하기 위하여, 마취제의 많은 부분을 차지하는 n-Alkanol을 이용하여, 소의 synaptosomal plasma membrane vesicles(SPMV)에서 n-Alkanol의 침투 정도를 형광 probe를 이용한 형광소광법을 통하여 검색하였다. n-Alkanols는 SPMV 외부 단층(outer monolayer)의 표면에 주로 분포하되 그 탄소수에 비례하여 소수성 부위에 분포되는 양이 증가되는 경향을 나타내었다(1-decanol은 제외). Methanol, Ethanol, 1-propanol, 1-butanol, 1-pentano, 1-hexanol, 1-heptanol, 1-octanol, 1-nonanol 및 1-decanil은 SPMV 외부 단층의 표면(친수성 부위)에 분포되는 것에 비하여 각각 949, 416.8, 214.8, 90.3, 53.7, 15.20, 6.80, 2.00, 1.03 및 2.40 배가 된다는 것을 확인하였다. 1-decanol은 $C_{10}$인데도 불구하고 $C_8$인 1-octanol에 비하여 적은 양이 소수성 부위에 침투 분포한다는 것이 확인되었다.
김해영(Hae Young Kim),조용훈(Yong Hoon Cho),박수은(Su Eun Park),권재영(Jae Young Kwon),이동형(Dong Hyung Lee) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.2
Purpose: The authors applied fetal stabilization and evaluated its efficacy as a therapeutic modality in the management of several congenital anomalies that can lead to perinatal respiratory distress, such as a congenital diaphragmatic hernia (CDH), large cervical lymphangioma or gastroschisis, etc. Methods: Between Oct. 2000 and Dec. 2004, 12 newborns, with a congenital diaphragmatic hernia or gastroschisis, were observed and fetal stabilization was applied to 4 neonates. Their clinical characteristics were then retrospectively reviewed. The protocol of this procedure was as followed, (1) monitoring of the fetal respiratory movement and heart beat using Doppler ultrasonography, (2) the intravenous administration of morphine (20 to 30 ㎎) and diazepam (5 ㎎) to the mother, (3) proceed to a cesarean section when any interruptions in the fetal movement were confirmed, (4) an intravenous injection of a pancuronimum (0.5 ㎎) through the umbilical vein, (5) an immediate tracheal intubation before disruption of the placenta, (6) clamping of the umbilical cord, (7) attempt a mechanical ventilation after delivery, (8) maintain percutaneous intravenous catheterization (PIC) and (9) evaluation of the neonate. Results: Of the 10 neonates with a CDH and the 2 with gastroschisis, fetal stabilization was applied to 3 CDH and 1 gastroschisis neonates, respectively. The survival rates were 85.7% that of conventional therapy, 66.7% for fetal stabilization in the CDH neonates and 100% for those with gastroschisis. Relatively, in those with a CDH where fetal stabilization was applied, large defects were observed and they were diagnosed at an earlier period, which could affect the mortality. Conclusion: In our experience, fetal stabilization seems to be useful as another alternative therapeutic modality for the control of respiratory distress in the management of a CDH and gastroschisis. However, further experiences with more clinical results will be required
권수아 ( Su Ah Kwon ),김은수 ( Eun Soo Kim ),박성천 ( Sung Chun Park ),김혜진 ( Hye Jin Kim ),권재영 ( Jae Young Kwon ),백승훈 ( Seung Hoon Baek ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.1
We report a case of unintentional intraoperative awareness during sevoflurane-remifentanil anesthesia in a 26 years old woman undergoing elective minimal invasive mitral valvuloplasty. Cardioprotective effects of sevoflurane were clinically most apparent when administered throughout the surgical procedure. Also use of sevoflurane during cardiopulmonary bypass decreases incidence of awareness. Although awareness during cardiac anesthesia has been previously described with sevoflurane, the implication of this case is that unexpected awareness can occur in patients with sevoflurane during cardiopulmonary bypass on cardiac surgery. Therefore, more attention is needed to use sevoflurane during cardiopulmonary bypass. (Korean J Anesthesiol 2009; 57: 100~3)
안면경련의 치료에 있어 CT 유도화 화학적 안면신경차단
정진우(Jin Ou Jeong),권재영(Jae Young Kwon),김해규 대한통증학회 1993 The Korean Journal of Pain Vol.6 No.2
Hemifacial spasm is a distressing condition characterized by involuntary, intermittent, uni- lateral twitching of all or parts of the muscles innervated by the facial nerve. This occurrence is most common in middle-aged women. Because etiology of idiopathic hemifacial spasm has remained undefined, no causative agent nor reliable treatment has been established. This report describes a case of CT guided chemical facial nerve block for the treatment of hemifacial spasm. An injection of small amount(0.1 ml) of alcohol(95%) provided relief of the facial spasms.
경동맥의 내막-중막 두께와 마취유도 시의 혈역학적 반응과의 상관관계
권수아 ( Su Ah Kwon ),김은수 ( Eun Soo Kim ),박성천 ( Sung Chun Park ),김경훈 ( Kyung Hoon Kim ),김해규 ( Hae Kyu Kim ),권재영 ( Jae Young Kwon ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.5
Background: The carotid intima-media thickness (IMT) have been known to be related to the degree of atherosclerosis and cardiovascular risk factors. The aim of this study was to elucidate the relationship of IMT and the hemodynamic changes during anesthetic induction. Methods: Two hundred fourteen patients scheduled for general anesthesia were studied. The blood pressures and heart rates during anesthetic induction and endotracheal intubation were measured. IMT was measured at right common carotid artery using M-mode ultrasonography after anesthesia, Results: Mean IMT of the patients was 0.611±0.146 (0.34-0.96) mm. IMT was significantly related with age, systolic blood pressure, the changes of blood pressure after induction, and the changes of blood pressure after intubation. IMT was not related for basal heart rate and the changes of heart rate during anesthetic induction and intubation. Conclusions: IMT is related with the magnitude of blood pressure decreasing during anesthetic induction and increasing during intubation. The further study is needed to evaluate the relationship of IMT and hemodynamic changes during other anesthetic practice. (Korean J Anesthesiol 2009;56:519~24)
소의 대뇌피질로부터 분리된 Synaptosomal Plasma Membrane Vesicle에서의 n - Alkanols의 침투정도
김인세(Inn Se Kim),권재영(Jae Young Kwon),백승완(S 대한통증학회 1993 The Korean Journal of Pain Vol.6 No.2
세포막에서 마취제의 작용점을 규명하기 위하여, 마취제의 많은 부분을 차지하는 n-Alkanol을 이용하여 , 소의 synaptosomal plasma membrane vesicles (SPMV)에서 n-Alkanol의 침투 정도를 형광 probe를 이용한 형광소광법을 통하여 검색하였다. n-Alkanols는 SPMV 외부 단층 (outer monolayer) 의 표면에 주로 분포하되 그 탄소수에 비례하여 소수성 부위에 분포된는 양이 증가되는 경향을 나타 N/A
백서의 좌골신경 손상에 미치는 저출력 레이저의 효과 ( IR - Laser )
정진우(Jin Ou Jeong),권재영(Jae Young Kwon),김해규 대한통증학회 1992 The Korean Journal of Pain Vol.5 No.1
N/A This study examined the microscopic changes following irradiation of infrared low dose laser on injured sciatic nerves of rats. In these days, many clinicians use the low-dose laser therapy in pain clinicians use the low-dose laser therapy in pain clinic on various fields and dieases. But the basic mechanism and indications were not known completely. Low-dose IR(infrared) laser irradiation applied to a crushed injured sciatic nerve of rats in the right leg in bilaterally inflicted crush injury. The results were as follows I) There are a little histological differences between laser treated group and nontreated group. 2) Low power IR-laser irradiation, when applied to the injured sciatic nerve, increased vascu- larization and relatively well conserved tissue organization. 3) There are little histological difference in distal muscle biopsy, but atrophic muscle fibers were seen partially. 4) We found out that more hypertrophic epineurium was present in laser-treated group.