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김민지 ( Min Ji Kim ),국진이 ( Ji Ni Kuk ),성지현 ( Ji Hyun Sung ),현창림 ( Chang Lim Hyun ),심순섭 ( Soon Sup Shim ),박철민 ( Chul Min Park ),김성엽 ( Sung Yob Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.6
Angiomyofi broblastoma (AMFB) is a rare mesenchymal tumor mostly involving the female lower genital tract. Although a large number of cases of vulva and vagina has been reported, a report on a case of the uterine cervix is uncommon. Despite unknown pathogenesis of AMFB, positive immunoreactivity for hormonal receptor of AMFB allows to make an assumption that the hormonal stimuli may have a role on the development of AMFB. Therefore, it is potential that estrogenic effect of tamoxifen gives stimuli on hormonally responsible mesenchymal cells, resulting in AMFB. We report a case of AMFB of the uterine cervix in a breast cancer patient with prolonged tamoxifen treatment with brief literature review.