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여성의 출산력과 초경 및 폐경 연령에 대한 설문지의 신뢰도
고광필,박수경,김연주,배지숙,전재관,곽진,유근영,Ko, Kwang-Pil,Park, Sue-Kyung,Kim, Yeon-Ju,Bae, Ji-Suk,Jun, Jae-Kwan,Gwack, Jin,Yoo, Keun-Young 대한예방의학회 2008 예방의학회지 Vol.41 No.3
Objectives : This study was performed to evaluate the reproducibility of a questionnaire concerned with reproductive history and to ascertain which characteristics of the subjects (age, the visit-revisit intervals, education and chronic disease) are associated with good reliability in the Korean Multi-Center Cancer Cohort (KMCC) study. Materials and Methods: A total of 19,688 participants were enrolled between 1993 and 2004. Among them, we selected 386 participants who were aged 40 or more and who re-visited within 8 years after the first visit. Reliability was measured by the percent agreement according to error range for the continuous variables and the percent agreement and kappa statistics for the categorical variables. Results : The pregnancy histories were reliable (kappa=0.67) and the reasons for being menopausal among the postmenopausal women were also reliable (kappa=0.92). The percent agreement of the breast-feeding history was high (96.1%), although the kappa statistic was low. For the continuous variables, when the error range of one variable was considered to be reliable, the percent agreement of the age at menarche and the age at the first full term pregnancy was good (69.4% and 83.6%), whereas that of the age at menopause was low (51.5%). The factors associated with high reliability were a younger age, the presence of chronic disease and a short visit-revisit time interval. Conclusions : The agreements for parity, the reasons for menopause, and the breastfeeding history in the reproductive history questionnaire used in the KMCC were relatively good. The questionnaire for the menarche age and the menopausal age might have lower reliability due to the difference between Korean age and American age. To obtain reliable information, more attention should be given to the items in questionnaire-based surveys, and especially for surveying old-aged women.
곽진,황승식,고광필,전재관,박수경,장성훈,신해림,유근영,Gwack, Jin,Hwang, Seung-Sik,Ko, Kwang-Pil,Jun, Jae-Kwan,Park, Sue-Kyung,Chang, Soung-Hoon,Shin, Hai-Rim,Yoo, Keun-Young 대한예방의학회 2007 예방의학회지 Vol.40 No.1
Objectives : Chronic infections with hepatitis B or C and alcoholic cirrhosis are three well-known major risk factors for liver cancer. Diabetes has also been suggested as a potential risk factor. However, the findings of previous studies have been controversial in terms of the causal association. Therefore, the aim of this study was to evaluate the association between serum glucose levels and liver cancer development in a Korean cohort. Methods : Thirty-six liver cancer cases were identified in the Korean Multi-Center Cancer Cohort (KMCC). Baseline information on lifestyle characteristics was obtained via questionnaire. Serum glucose levels were measured at the study's enrollment. Relative risks (RRs) were estimated using a Cox proportional hazard regression model. The adjusting variables included age, gender, smoking history, alcohol consumption, body mass index, and hepatitis B surface antigen (HBsAg) seropositivity. Results : The RRs of serum glucose for liver caner were 1.20 (95% CI = 0.48-2.99) for the category of 100 to 125 mg/dL of serum glucose and 2.77 (95% CI = 1.24-6.18) for the >126 mg/dL serum glucose category (both compared to the <100 mg/dL category). In a subgroup analysis, the RR of serum glucose among those who were both HBsAg seronegative and non-drinkers was 4.46 (95% CI = 1.09-18.28) for those with glucose levels >100 mg/dL. Conclusions : The results of this study suggest that a high level of serum glucose can increase liver cancer risk independently of hepatitis infection and drinking history in Koreans. This study implies that glucose intolerance may be an independent risk factor for liver cancer.
조사 계절에 따른 식품섭취빈도 조사의 평균 섭취 횟수와 섭취량 변화
양재정,임현술,고광필,안윤진,안윤옥,박수경,Yang, Jae-Jeong,Lim, Hyun-Sul,Ko, Kwang-Pil,Ahn, Youn-Jhin,Ahn, Yoon-Ok,Park, Sue-Kyung 대한예방의학회 2007 예방의학회지 Vol.40 No.3
Objectives : This study was conducted to investigate the systematic error, such as seasonal change or inadequate food items, in a food frequency questionnaire administered to workers in a Nuclear Power Plant, Korea. Methods : We performed three repeat-tests with 28 subjects on May 13, July 8 and Dec 16, 1992. Our food frequency questionnaire (FFQ) comprised 84 foods organized into 7 food-groups, and was composed of the items of usual intake frequency (8 categories) and the amount per intake (3 or 4 categories) over the previous year. We compared the means of intake frequency and the frequency of the portion-size according to each season using Repeated Measures ANOVA and Pearson's chisquare test with Fisher's exact test. Results : We found the significant seasonal changes of several food items in intake frequency measurement. These items were typical seasonal foods such as mandarin orange, plum and green vegetables, while the single questions consisted of inadequate food items such as thick beef or similar soup and various kimchi products. Significant seasonal changes in portion-size were found in only two items: cooked rice-brown and fresh frozen fishes. Conclusions : The systematic errors observed could caused loss of validity in the FFQ. Consideration should be given for seasonal variation in FFQ survey and methodological concerns are needed to improve the quality for measuring usual diet pattern.
이은하,박수경,고광필,조인성,장성훈,신해림,강대희,유근영,Lee, Eun-Ha,Park, Sue-K.,Ko, Kwang-Pil,Cho, In-Seong,Chang, Soung-Hoon,Shin, Hai-Rim,Kang, Dae-Hee,Yoo, Keun-Young 대한예방의학회 2010 예방의학회지 Vol.43 No.2
Objectives: The aim of this study was to evaluate the association between cigarette smoking and total mortality, cancer mortality and other disease mortalities in Korean adults. Methods: A total of 14 161 subjects of the Korean Multi-center Cancer Cohort who were over 40 years of age and who were cancer-free at baseline enrollment reported their lifestyle factors, including the smoking status. The median follow-up time was 6.6 years. During the follow-up period from 1993 to 2005, we identified 1159 cases of mortality, including 260 cancer mortality cases with a total of 91 987 person-years, by the national death certificate. Cox proportional hazard regression model was used to estimate the hazard ratio (HR) of cigarette smoking for total mortality, cancer mortality and disease-specific mortality, as adjusted for age, gender, the geographic area and year of enrollment, the alcohol consumption status, the education level and the body mass index (BMI). Results: Cigarette smoking was significantly associated with an increased risk of total mortality, all-cancer mortality and lung cancer mortality (p-trend, < 0.01, <0.01, <0.01, respectively). Compared to non-smoking, current smokers were at a higher risk for mortality [HR (95% CI)=1.3 (1.1 - 1.5) for total mortality; HR (95% CI)=1.6 (1.1 -2.2) for all-cancer mortality; HR (95% CI)=3.9 (1.9-7.7) for lung cancer mortality]. Conclusions: This study's results suggest that cigarette smoking might be associated with total mortality, all-cancer mortality and especially lung cancer mortality among Korean adults.
급수압 변화에 따른 대변기와 세면기의 급배수 소음 특성에 관한 실험적 연구
이태강(Lee, Tai-Gang),고광필(Ko, Kwang-Pil),최은석(Choi, Eun-Suk),김항(Kim, Hang),김선우(Kim, Sun-Woo) 한국소음진동공학회 2007 한국소음진동공학회 논문집 Vol.17 No.3
This study aims to evaluate noise emission from water supply and drain installations in apartment bathroom. These noise were one of the most annoying noise sources in apartment houses. Especially, drain plumbing system have used bellow bathroom ceiling, it was very discomfort to hear the noise in bellow apartment. Noise of closets and faucets were measured which were main noise source, then these noise were evaluate and analyzed the emitting characteristics varying the supplying water pressure. As increasing the water pressure, also total noise level of the water supplying stool noise and faucet noise were increased. Especially the water closet showed remarkably the increasing noise level in middle and high frequency bandwidth, while the noise level of faucets increased in $50\;Hz{\sim}250\;Hz$ of low frequency bandwidth. Vortex closet were favorable to syphon closet, and lever faucet were favorable to conventional lavatory faucet on reducing the noise. Above these results could be used in basic data establishing KS (Korean Standard) for evaluation and rating procedure and measures reducing these noise.