폐로 전이한 악성 에나멜모세포종의 세침흡인 세포학적 소견 - 1예 보고 -

강윤경,박인애,임창윤,함의근,이상국,Kang, Yun-Kyung,Park, In-Ae,Lim, Chang-Yun,Ham, Eui-Keun,Lee, Sang-Kook 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.2

We describe the cytologic features of metastatic ameloblastoma which presented as multiple bilateral lung nodules. The patient was a 22-year-old male who had recurrent ameloblastoma of the mandible 7 years after the diagnosis of primary lesion. Fine needle aspiration of one of the pulmonary nodules revealed patchy arrangement of cell clusters with outer palisading columnar cells and inner irregular loose polygonal cells. Most of tumor cells had plenty cytoplasm and ovoid nuclei which lacked either pleomorphism or hyperchromatism. The cytologic findings corresponded with histologic features of the primary site which was also benign looking ameloblastoma.

염분(鹽分)과 태양광(太陽光)에 동시(同時) 노출(露出)된 염색모발(染色毛髮)의 색상변화(色相變化)

강윤경 ( Yun Kyung Kang ),조지훈 ( Ji Hoon Cho ) 한국미용학회 2008 한국미용학회지 Vol.14 No.1

Because three sides of our country is surrounded by the sea, chances are very high for our hair to be exposed to the saline air. Expecially, during the summer vacation time on the seashore, because our hair is directly open to the strong ultraviolet and the seawater, our hair is highly likely to be damaged. Until now, there have been several researches investigating effects of the solar light exposure on the chemico-physical change of hair; however, effects of the saline water on hair have not been fully investigated. Therefore, in this thesis, the color change of the dyed hair is experimentally evaluated after dipping the hair in the saline water and exposing to the solar light. SEM images are also taken to compare and analyze the color change of the dyed hair with the degree of the surface damage. Through experiments, greater color change is measured on the hair which is dipped in the saline water with higher concentration and exposed to the solar light for longer period of time. This result means that the hair gets sensitive to the solar light leading to greater color change if the hair is affected to the saline water. Damaged hair also shows greater color change than the virgin hair because damaged hair is more sensitive to the solar light due to the surface damage. From surface investigation based on SEM images, hairs with greater color change have greater damages on its surface. Finally, the degree of color change and the surface damage of hair is greater for the hair dyed with reddish color (Black<Brown<Red<Yellow), which means that the hair dyed by red or yellow color reacts more actively with the solar light than the hair dyed by black or brown color.

소형챔버를 이용한 건축자재의 휘발성유기화합물과 폼알데하이드의 흡착성능에 관한 연구

강윤경(Kang Yoon-Kyung),임정연(Lim Jung-Yeon),장성기(Jang Seong-Ki),이윤규(Lee Yun-Gyu) 대한건축학회 2009 대한건축학회논문집 Vol.25 No.5

In this study, we are investigate for functional building materials such as hygrothermal, adsorption, mold or bacteria growth resistance, an anion emission, far-infrared radiation functional building material in Korea. Also, the performance of sorptive building materials to indoor air pollutant is studied in this paper. The effects of sorptive building materials with respect to reduction of BTEXS(Benzene, Toluene, Ethylbenzene, Xylene, Styrene) mixed gas and formaldehyde concentrations were evaluated during 7days using the small chamber system. A ceiling board(product A) and a wall board(product C) showed decreasing effects of 89% and 92% for formaldehyde, respectively. Also, another wall board(product D) showed decreasing effect of 66% for BTEXS mixed gas. However, another ceiling board(product B) showed no significant decreasing effect.

소형챔버를 이용한 건축자재의 휘발성유기화합물과 폼알데하이드 방출량 평가

강윤경(Yoon-Kyung Kang),김현진(Hyun-Jin Kim),이윤규(Yun-Gyu Lee) 한국실내환경학회 2008 한국실내환경학회지 Vol.5 No.3

This study was performed to analysis the concentration of TVOC, 5VOC and formaldehyde for building material of total 262 using 20L test chamber. The concentration of TVOC, 5VOC and formaldehyde were measured 1.001㎎/㎡ㆍh, 43.032㎍/㎡ㆍh, 0.012㎎/㎡ㆍh, respectively. TVOC concentration of paint and floor covering occupied the largest concentration of the indoor building materials as 2.689㎎/㎡ㆍh, 2.120㎎/㎡ㆍh, respectively. 5VOC concentration of floor covering was measured 106.636㎍/㎡ㆍh. Toulene and xylene were occupied the largest part of the 5VOC as 51.2% and 33.1%, respectively. The concentration of formaldehyde for furniture materials occupied the largest concentration of the indoor building material as 0.072㎎/㎡h.

대장 용종에서 렙틴 발현에 따른 임상병리학적인 특성의 차이

옥경선 ( Kyung Sun Ok ),김유선 ( You Sun Kim ),김형훈 ( Hyung Hun Kim ),류수형 ( Soo Hyung Ryu ),이정환 ( Jung Hwan Lee ),문정섭 ( Jeong Seop Moon ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2010 대한소화기학회지 Vol.56 No.1

Background/Aims: Colorectal adenoma and cancer are known to be associated with obesity. Leptin, an adipocyte-derived hormone that plays a crucial role in obesity has been suggested as a growth factor in colon cancer. However, the association between adenoma and leptin remains controversial. We evaluated the leptin expression in human colorectal adenoma and its correlation to clinicopathologic factors. Methods: Leptin expression was assessed by immunohistochemistry in 91 samples of colorectal adenoma larger than 5 mm, which were removed by endoscopic polypectomy. All patients underwent colonoscopy for cancer screening at Seoul Paik Hospital from 2007 to 2008 and we only included the patients less than 50 years of age. Leptin expression and its relationship with clinicopathologic features were analyzed. Results: Eighty samples were available for the interpretation of leptin expression and showed positive in 42 (52.5%) cases and negative in 38 (47.5%) cases. As body mass index (BMI) increased based on World Health Organization (WHO) classification the positivity of leptin expression also increased (ptrend=0.02), in leptin positive group, the correlation of leptin expression with adenoma size and histological showed positive tendency without statistical significance. Conclusions: Leptin expression of colorectal adenoma was associated with BMI. The question of whether leptin contributes to colorectal adenoma development is unresolved and will require additional studies. (Korean J Gastroenterol 2010;56:20-26)

접형동, 사골동의 비강형 자연살해/T 세포 림프종에 의한 안와첨증후군 1예

백승화,염동주,강윤경,성미선,문상웅,Seung Hwa Baik,Dong Ju Yeom,Yun Kyung Kang,Mi Sun Sung,Sang Woong Moon 대한안과학회 2010 대한안과학회지 Vol.51 No.2

Purpose: To report a case of nasal-type NK/T cell lymphoma occurring in the sphenoid and ethmoid sinuses of an orbital apex syndrome patient. Case summary: A 61-year-old male patient visited our hospital for the impairment of vision in the right eye for the previous month, and for right-side blepharoptosis, pain around the eyeball, and limitation of extraocular movement in the right eye for three days earlier. In MRI (magnetic resonance image) and CT (computed tomography), shades with vague boundaries were observed in the right sphenoid and ethmoid sinuses, and open biopsy and decompression were performed for the lesions. After the surgery, the vision of the right eye increased, and improvement was observed in the right blepharoptosis, the pain around the eyeball, and in the limitation of motility of the extraocular muscle in the right eye. The patient was diagnosed with nasal type NK/T cell lymphoma in biopsy, and radiotherapy and chemotherapy were performed. J Korean Ophthalmol Soc 2010;51(2):286-291

쥐의 타액선 방사선조사 후 만성반응에 Pentoxifylline과 Diltiazem이 미치는 영향

서현숙,양광모,강윤경,Suh, Hyun-Suk,Yang, Kwang-Mo,Kang, Yun-Kyung 대한방사선종양학회 1999 Radiation Oncology Journal Vol.17 No.3

목적 : 두경부암 환자들은 방사선조사 후 부작용으로 타액선의 기능부전인 구강건조증이 흔히 유발되어 치료 후 회복이 늦어지고 삶의 질이 저하된다. 방사선조사와 함께 혈류개선제로 알려져 있는 pentoxifylline (PTX)과 칼슘 통로차단제로 알려져 있는 diltiazem (DTZ)을 단독 또는 병합으로 투여한 후 타액선의 만성변화를 분석하여 이 약제들의 방사선손상 억제 가능성을 분석해 보고자 하였다. 대상 및 방법 : Sprague-Dawley 쥐 16마리를 네 군 즉, 1) 방사선조사 단독군, 2) 방사선조사와 PTX 투여군, 3) 방사선조사와 DTZ 투여군, 4) 방사선조사와 PTX, DTZ의 병합투여군으로 분류하였다. 4 MV 선형가속기를 이용하여 16 Gy 일회로 타액선 부위에 방사선조사를 시행하였다. PTX은 방사선조사 20분 전에 kg당 50 mg을, DTZ은 방사선조사 30분 전에 kg당 20 mg을 복강 내로 각각 투여하였다. 방사선조사후 10주와 16주후에 타액선을 절제하여 H&염색을 하여 병리학적 소견을 관찰하였고 만성변화의 객관적 지표인 세포질내 공포 형성의 정도를 백분율로 측정하여 각 군간의 평균값을 비교하여 통계적인 유의성을 $x^2$-검사에 의해 확인하였다. 결과 : 방사선조사 10주 후 타액선의 선방세포질 내에서 다수의 공포형성이 관찰되었으며 방사선조사와 PTX 투여군, 또는 PTX과 DTZ 병합투여군에서는 이들 세포질내 공포 형성이 통계적으로 의미 있게 감소하였다(p vaiue, 0.001). 그러나 DTZ 투여군에서는 세포질내 공포 형성 정도가 방사선조사단 독군에 비해 통계적으로 의미 있게 감소되지 않았다(p value, >0.05). 방사선조사 후 16주에 관찰한 실험 군들에서도 선방세포질내 공포형성의 차이가 10주군들과 각기 유사한 소견을 보였으며 10주와 다른 점은 선방세포의 전체 수가 감소된 것과 간질 내 섬유화의 증가였다. 결론 : 방사선조사를 받은 쥐의 타액선에서 PTX 투여, 혹은 PTX과 DTZ 병합 투여결과 만성손상이 감소되었음을 관찰하였고 이로 미루어 보아 PTX이 방사선조사후 발생하는 구강건조증을 예방하는 효과적인 약제가 될 수 있으리라 생각한다. Purpose : To elucidate the effects of pentoxifylline and diltiazem on the late response of the salivary glands of the rat after irradiation. Materials and Methods : Sixteen Sprague-Dawley rats were divided into 4 groups : (a) irradiation alone (b) irradiation with pentixifylline (PTX) (c) irradiation with diltiazem (DTZ) (d) irradiation with both PTX and DTZ. Irradiation was given in a single fraction of 16 Gy using 4 MV photon energy through an anterior port encompassing the left side of the salivary gland leaving the right side of salivary gland as a control. PTX, 20 mg/kg and/or DTZ, 50 mg/kg were infused intraperitoneally before irradiation, Two rats from each group were sacrificed on the 10th week and the rest was sacrificed on the 16th week after irradiation. Histopathologic examinations were undertaken for each section and the proportion of vacuolated cells out of the total number of cells under light microscopic fields was calculated. The statistical significance in the difference of the proportion of the vacuolated cells among the experimental groups was evaluated by a $x^2$-test. Results : Irradiated salivary glands of the 10th week group revealed markedly increased number of vacuolated cells compared to those of unirradiated control. The proportion of vacuolated cells was significantly reduced in both the PTX group (p value=0.001) and the combined PTX and DTX group compared to those of irradiation alone group. The DTZ alone group did not reveal the significant reduction of vacuolated cells compared to those of irradiation alone group (p value, >0.05). The 16th week groups revealed similar findings to those of the 10th week group, but the degree of chronic inflammatory cell infiltrates and interstitial fibrosis was increased and the number of acinar cells was reduced compared to those of the 10th week group. Conclusions : PTX significantly reduced the late radiation response of salivary glands, but DTZ did not reduce the same degree as PTX did. Taking the positive results of this study into consideration, it seems reasonable to apply PTX into the clinical trial for the head and neck irradiation to reduce the late radiation sequelae of salivary glands in the near future. At the same time the further experiment to clarify the subcellar mechni는 involved in PTX should be preceded.

Lycoris 속의 RAPD 분석과 자생지 분포 및 개화특성에 따른 유연관계

차재영,정연옥,신상민,강윤경,박종군,박노복,Cha, Jae-Young,Jung, Yen-Ok,Shin, Sang-Min,Kang, Yun-Kyung,Park, Jong-Kun,Park, Nou-Bog 한국생명과학회 2006 생명과학회지 Vol.16 No.7

Ten species of Lycoris was selected for establishment of phylogenetic relationships using random amplified polymorphic DNA (RAPD) analysis, the native distribution and flowering characterestics. On the basis of the dendrogram constructed with the similarity coefficients, 10 Lycoris species were divided into two clusters. L. sprengeri and L. incannta were showed very high similarity in the RAPD analysis, same flowering time and flower color as pink. The leaf of L. squamigera. L. sanguinea, L. koreana, L. sprengeri and L. incanata emergenced in spring. The L. squamigera and L. sanguinea were showed high similarity in same cluster. Also L. koreana, L. sprengeri and L. incanata were showed high similarity in same cluster. The flower of L. radiata, L. radiata var pumila, L. albiflora and L. traubii was spider. These species was showed very low similarity in another Lycoris species. 본 연구에서는 RAPD 분석 기법과 자생지 분포와 개화특징을 이용한 유연관계를 분석하기 위하여 10종의 Lycoris 종을 선별하여 연구를 수행하였다. 10종의 상사화 종은 크게 두 군집으로 분류되었다. L. sprengeri와 L. incanata은 가장 높은 상동성을 보였으며, 같은 개화 시기와 분홍색의 화색을 가지고 있었다. 춘기출엽형은 L. squamigera, L. sanguinea, L. koreana, L. sprengeri 그리고 L. incanata이었으며, L. squamigera와 L. sanguinea는 같은 군집 안에서 높은 상동성을 보였다. 또한 L. koreana, L. sprengeri 그리고 L. sprengeri 그리고 L. incanata도 군집안에서 높은 상동성을 보였다. L. radiata, L. radiata var pumila, L. albiflora 그리고 L. traubii의 꽃은 spider형이며 이러한 종은 다른 종과의 유연관계가 매우 낮은 상동성을 보였다.

비대칭적인 네트워크 환경에서의 Out-of-Order 패킷 감소를 위한 MPTCP 중복패킷 전송에 관한 연구

박지훈(Jihoon Park),강윤경(Yun Kyung Kang),김대영(Dae-Young Kim) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2

현대의 네트워크상에서 발생되는 트래픽은 라이브 비디오 스트리밍과 같은 낮은 지연을 요구하는 실시간 애플리케이션 서비스 트래픽이 주를 이룬다. 이때 MPTCP를 사용하게 될 시 여러 경로를 동시에 가용하여 질 높은 서비스를 제공할 수 있게 된다. 하지만 MPTCP에서 사용되는 여러 네트워크 환경이 비대칭적일 경우엔 OFO 패킷이 생성되어 HoL 차단 현상이 발생된다. MPTCP는 TCP와 같이 올바른 순서로 정렬된 데이터만을 상위 계층으로 전달한다. 따라서 OFO 패킷으로 인한 HoL 차단 현상이 일어날 시 MPTCP는 데이터를 상위 계층으로 전달하지 못해 결국 실시간 앱 서비스는 잦은 지연현상을 겪게 된다. 본 연구에서는 이러한 비대칭적인 네트워크 환경에서의 OFO 패킷 생성으로 인한 서비스 지연 문제를 해결하기 위해 중복 패킷 아이디어를 채택하였고 여러 경로를 통한 중복 패킷 전송 방식이 다른 스케줄러와 비교하여 OFO 패킷을 얼마나 감소시키는지 실험해보았다.

소아에서 결핵성 중이염 1례

김은아,함세창,김영균,박용원,강윤경,Kim, Eun Ah,Ham, Se Chang,Kim, Young Kyoun,Park, Yong Won,Kang, Yun Kyung 대한소아감염학회 2002 Pediatric Infection and Vaccine Vol.9 No.1

결핵성 중이염은 매우 드문 질환이나 최근 결핵의 유병률이 증가하는 추세이므로 장기간의 항생제 치료에도 반응하지 않는 만성 중이염의 경우 결핵성 중이염의 가능성을 염두에 두어 감별진단 하여야 한다. 이런 관심은 조기 진단과 이에 따른 적절한 치료를 하게 되어 고막 파열, 청력 소실 및 안면신경마비와 같은 중한 합병증을 줄일 수 있을 것이다. Tuberculous otitis media is a very rare disease in extrapulmonary tuberculosis and in chronic otitis media nowadays. The characteristic signs seem to have altered from the past ones. And the suspicion index is very low that there is often a considerable delay prior to diagnosis. This might result in irreversible complications such as hearing loss, facial nerve paralysis and labyrinthitis. It is difficult to be defined by culture, so many patients with tuberculous otitis media are subjected to have surgery without a correct etiologic diagnosis. Therefore bacteriologic study of secretion and pathologic examinations of biopsied tissue are mandatory. We report one year and 11 months old boy with tuberculous otitis media having painful otorrhea and perforated tympanic membrane diagnosed by histologic finding and polymerase chain reaction(PCR). And we would like to emphasize the fact that tuberculous otitis media must be considered in the differential diagnosis of persistent suppurative otitis media despite appropriate antibiotic therapy considering the increasing tendency in incidence of Tuberculosis in Korea these days.