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강원준,Won Jun Kang,M.D.,Ph.D. 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.3
Radioactive iodine therapy is widely used in patients diagnosed with differentiated thyroid cancer. Clinicians have been supplied with several guidelines on how to ablate thyroid tissue or treat thyroid cancer. Here, we review the general procedures involved in patient preparation and special considerations that must be taken before initiating radioactive iodine therapy. <B>(Ko</B><B></B><B>rean J Endocrine Surg 2008;8: 167-170)</B>
Tc-99m 표지 항과립구항체 면역신티그라피를 이용한 골수염의 진단
강원준,정준기,여정석,홍미경,정재민,이동수,이상훈,최인호,이명철 ( Won Jun Kang,June Key Chung,Jeong Seok Yeo,Mee Kyoung Hong,Jae Min Jeong,Dong Soo Lee,Sang Hoon Lee,In Ho Choi,Myung Chul Lee ) 대한핵의학회 1998 핵의학 분자영상 Vol.32 No.4
Purpose: The purpose of this study was to evaluate the diagnostic accuracy of Tc-99m labeled antigranulocyte antibody immunoscintigrapy in the diagnosis of osteomyelitis and compare with the results of triphasic bone scan. Materials and Methods: The study popula- tion was 39 patients (22 male, 17 female) who had uncertain diagnoses of osteomyelitis. Fifteen patients had history of orthopedic surgery, and 5 had previous fracture. One milligram of monoclonal antibody against NCA-95 was labeled with 370 MBq of Tc-99m, injected intravenously, and 4 hour images were obtained. Triphasic bone scan images were obtained in 30 p;tients. The final diagnosis was confirmed by bacteriologic culture, biopsy or long term clinical follow up. Results: Twenty one patients were confirmed to have osteomyelitis (1 acute, 20 chronic). Eighteen patients were without osteomyelitis. Antigranulocyte antibody immunoscintigraphy had a sensitivity of 71% (15/21), and a specificity of 89% (16/18), while the sensitivity and specificity of triphasic bone scan was 93% (13/14) and 38% (6/16), respectively. Antigranulocyte antibody scan showed higher specificity of 100% (11/11) in comparison with 33% (3/9) of triphasic bone scan in patients with history of orthopedic surgery or fracture. Conclusion: Antigranulocyte antibody immunoscintigraphy is more specific than that of triphasic bone scan and may be helpful in patients with history of surgery or fracture. However, sensitivity is lower than triphasic bone scan in the detection of chronic osteomyelitis. (Korean J Nucl Med 1998;32:344-53)
BLT 방정식을 이용하여 사각 aperture 사이를 통과한 고출력 전자파가 공진기 내부에 미치는 영향에 관한 연구
강원준(Won-june Kang),이비오(Vea-o Lee),문상곤(Sang-kon Mun),김준호(Jun-ho Kim),정용식(Young-seek Chung) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.7
In this paper, we studied on the influence of the EM waves on the cavity with rectangular apertures using BLT equation. The proposed method can solve the electromagnetic coupling on the cavity with rectangular apertures. Also, we expect that this paper will help design shielding structures for high power EM waves. The simulation results were compared with those of the full wave analysis and agreed with those of results.
특발성 폐섬유증에서 발견된 폐결절의 악성여부 감별에서 F-18 FDG PET의 유용성
김범산 ( Bom Sahn Kim ),강원준 ( Won Jun Kang ),이동수 ( Dong Soo Lee ),정준기 ( June Key Chung ),이명철 ( Myung Chul Lee ) 대한핵의학회 2006 핵의학 분자영상 Vol.40 No.3
목적: 특발성 폐섬유증(Idiopathic pulmonary fibrosis: IPF)에서 폐암의 발생빈도가 정상인에 비하여 증가되어 있음이 알려져 있다. IPF 환자의 흉부전산화단층촬영(chest CT)에서 폐 결절이 관찰되는 경우 폐암의 발생과 자체 IPF자체의 결절을 감별하기 어렵다. 이 연구에서는 IPF 환자의 chest CT에서 관찰된 결절의 악성 여부를 FDG PET을 이용해 분석하였다. 대상 및 방법: IPF로 진단된 환자 중, chest CT에서 악성 결절이 의심되어 FDG PET을 시행한 16명을 대상으로 하였다. 총 16명 (남: 14, 여: 2, 나이: 67.53±9.83세)의 환자에서 관찰된 28개의 결절에 대하여 FDG PET과 CT소견을 분석하였다. 대상 환자 중 2명은 소세포암과 성문하암으로 치료 받은 병력이 있었으며, 나머지 환자는 악성종양의 기왕력이 없었다. 결절의 악성도 여부는 조직검사와 CT 추적검사로 판정하였다. 결과: 10개의 결절은 폐암으로 진단되었고, 18개의 결절은 양성 결절로 판정되었다(조직병리검사: 6예, chest CT 추적검사: 22예). FDG PET의 예민도는 100%이었으며 특이도는 94.4%이었다. 크기와 형태 및 크기 변화 등을 참고한 CT의 예민도는 70%이었고, 특이도는 44.4%이었다. 악성 결절의 maxSUV는 7.68±3.96, 양성 결절은 1.22±0.65이었다(p<0.001). 폐섬유증부위에서 측정한 maxSUV는 1.80±0.43로써 악성 결절보다 낮은 값이었으며, 양성 결절보다는 높은 값이었다(p<0.001; p<0.001). CT에서 측정한 악성 결절의 크기는 23.95±10.15 mm, 양성결절은 10.83±5.23 mm이었다(p<0.02). 결론: FDG PET은 IPF 환자의 CT에서 발견된 폐 결절을 감별하는데 도움이 되었다. Purpose: Incidence of lung cancer in patients with idiopathic pulmonary fibrosis (IPF) is known to be higher than that in general population. However, it is difficult to discriminate pulmonary nodule in patients with IPF, because underlying IPF can be expressed as lung nodules. We evaluated the diagnostic performance of FDG PET in discriminating lung nodule in patients with IPF. Methods: We retrospectively reviewed 28 lung nodules in 16 subjects (age; 67.53±9.83, M:F=14:2). Two patients had previous history of malignant cancer (small cell lung cancer and subglottic cancer). The diagnostic criteria on chest CT were size, morphology and serial changes of size. FDG PET was visually interpreted, and maximal SUV was calculated for quantitative analysis. Results: From 28 nodules, 18 nodules were interpreted as benign nodules, 10 nodules as malignant nodules by histopahthology or follow-up chest CT. The sensitivity and specificity of FDG PET were 100% and 94.4%, while those of CT were 70.0% and 44.4%, respectively. Malignant nodule was higher maxSUV than that of benign lung nodules (7.68±3.96 vs. 1.22±0.65, p<0.001). Inflammatory lesion in underlying IPF was significantly lower maxSUV than that of malignant nodules (1.80±0.43, p<0.001). The size of malignant and benign nodule were 23.95±10.15 mm and 10.83 ±5.23 mm (p<0.01). Conclusion: FDG PET showed superior diagnostic performance to chest CT in differentiating lung nodules in patients with underlying IPF. FDG PET could be used to evaluate suspicious malignant lung nodule detected by chest in patients with IPF. (Nucl Med Mol Imaging 2006;40(3):163-168)